FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0007, 690 aa 1>>>pF1KF0007 690 - 690 aa - 690 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8546+/-0.00103; mu= -3.3154+/- 0.062 mean_var=362.1777+/-75.822, 0's: 0 Z-trim(115.3): 19 B-trim: 448 in 1/53 Lambda= 0.067393 statistics sampled from 15882 (15898) to 15882 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.488), width: 16 Scan time: 4.260 The best scores are: opt bits E(32554) CCDS47295.1 FCHSD1 gene_id:89848|Hs108|chr5 ( 690) 4621 463.4 4.8e-130 CCDS8218.2 FCHSD2 gene_id:9873|Hs108|chr11 ( 740) 1238 134.5 5.2e-31 >>CCDS47295.1 FCHSD1 gene_id:89848|Hs108|chr5 (690 aa) initn: 4621 init1: 4621 opt: 4621 Z-score: 2448.2 bits: 463.4 E(32554): 4.8e-130 Smith-Waterman score: 4621; 100.0% identity (100.0% similar) in 690 aa overlap (1-690:1-690) 10 20 30 40 50 60 pF1KF0 MQPPPRKVKPAQEVKLRFLEQLSILQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MQPPPRKVKPAQEVKLRFLEQLSILQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 AGPFLKREGHRSGEMDSRGRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTGRSAKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 AGPFLKREGHRSGEMDSRGRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTGRSAKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 QVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 HSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 HSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 LSEHLRDPLTSLSHTELEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LSEHLRDPLTSLSHTELEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 FQPAGTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRRQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FQPAGTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRRQQA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 SEREAPSIEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQAQDEVEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SEREAPSIEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQAQDEVEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 ERRLSEARLSQRDLSPTAEDAELSDFEECEETGELFEEPAPQALATRALPCPAHVVFRYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ERRLSEARLSQRDLSPTAEDAELSDFEECEETGELFEEPAPQALATRALPCPAHVVFRYQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 AGREDELTITEGEWLEVIEEGDADEWVKARNQHGEVGFVPERYLNFPDLSLPESSQDSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 AGREDELTITEGEWLEVIEEGDADEWVKARNQHGEVGFVPERYLNFPDLSLPESSQDSDN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 PCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 SLLVEELLGPPGPPELSDPEQMLPSPSPPSFSPPAPTSVLDGPPAPVLPGDKALDFPGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SLLVEELLGPPGPPELSDPEQMLPSPSPPSFSPPAPTSVLDGPPAPVLPGDKALDFPGFL 610 620 630 640 650 660 670 680 690 pF1KF0 DMMAPRLRPMRPPPPPPAKAPDPGHPDPLT :::::::::::::::::::::::::::::: CCDS47 DMMAPRLRPMRPPPPPPAKAPDPGHPDPLT 670 680 690 >>CCDS8218.2 FCHSD2 gene_id:9873|Hs108|chr11 (740 aa) initn: 1185 init1: 478 opt: 1238 Z-score: 670.2 bits: 134.5 E(32554): 5.2e-31 Smith-Waterman score: 1549; 39.7% identity (67.7% similar) in 731 aa overlap (1-677:1-721) 10 20 30 40 50 60 pF1KF0 MQPPPRKVKPAQEVKLRFLEQLSILQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKL ::::::::: .::.: .::.. ::. .: : :::::.:..:...:::::::.:..::: CCDS82 MQPPPRKVKVTQELKNIQVEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGMQKL 10 20 30 40 50 60 70 80 90 100 110 pF1KF0 AGPFLKRE--GHRSGEMDSRGRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGG---TG :. .:::. : .. . .. :... .:. .:..:. .:.:.. . :... . : CCDS82 ASQYLKRDWPGVKADDRNDY-RSMYPVWKSFLEGTMQVAQSRMNICENYKNFISEPARTV 70 80 90 100 110 120 130 140 150 160 170 pF1KF0 RSAKEQVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRS :: ::: :.. ...: . :.:. ..:..:....: : . :.. ..::: :..:. : CCDS82 RSLKEQQLKRCVDQLTKIQTELQETVKDLAKGKKKYFETEQMAHAVREKA-DIEAK---S 120 130 140 150 160 170 180 190 200 210 220 230 pF1KF0 DHGIFHSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLK ..:.:: :::: :.::.:. .. ... :::.:::.:.:.::: :.::: .: ..: CCDS82 KLSLFQSRISLQKASVKLKARRSECNSKATHARNDYLLTLAAANAHQDRYYQTDLVNIMK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KF0 ALVSELSEHLRDPLTSLSHTELEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSP :: ... .::.: : ..:.::::. ... . . ...:.: . .:.::::: .:: CCDS82 ALDGNVYDHLKDYLIAFSRTELETCQAVQNTFQFLLENSSKVVRDYNLQLFLQENAVFHK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KF0 TPPQQFQPAGTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQ : :::: .: :: . :.. . .:.::... ..:.::..: : .:::. :: CCDS82 PQPFQFQPCDSDTSRQLE-SETGTTEEHSLNKEARKWATRVAREHKNIVHQQRVLNDLEC 300 310 320 330 340 350 360 370 380 390 400 410 pF1KF0 RRQQASEREAPSIEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQAQ . .::. .::...:.::.::.:.. ..:. ::: ::. :..:. ::: ::.:.. CCDS82 HGAAVSEQSRAELEQKIDEARENIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQVM 360 370 380 390 400 410 420 430 440 450 460 470 pF1KF0 DEVEQERRLSE-ARLSQRDLSPTAEDAELSDFEECEETGELFEEPAPQALAT-RALPCPA .:.:.:: : :. : :.: . :: :.. ..:.. . . .: : : CCDS82 EELENERWARPPAVTSNGTLHSLNADTEREEGEEFEDNMDVFDDSSSSPSGTLRNYPLTC 420 430 440 450 460 470 480 490 500 510 520 pF1KF0 HVVFRYQAGREDELTITEGEWLEVIEEGDADEWVKARNQHGEVGFVPERYLNFPD----L .::. :.:.. ::::: : : :::::.:: ..::::::. :.::.:::.::.:: : CCDS82 KVVYSYKASQPDELTIEEHEVLEVIEDGDMEDWVKARNKVGQVGYVPEKYLQFPTSNSLL 480 490 500 510 520 530 530 540 550 560 570 pF1KF0 SLPES-------SQDSDNPCGAE---------PTAFLAQALYSYTGQSAEELSFPEGALI :. .: :. :.: :: .. ...:::.: ::. .::::::::.: CCDS82 SMLQSLAALDSRSHTSSNSTEAELVSGSLNGDASVCFVKALYDYEGQTDDELSFPEGAII 540 550 560 570 580 590 580 590 600 610 620 630 pF1KF0 RLLPRA-QDGVDDGFWRGEFGGRVGVFPSLLVEELLGPP-GPPELSDPEQMLPSPSPPSF :.: . :: :::::.:::.::.:::::.::::: . : :. :::.: . CCDS82 RILNKENQD--DDGFWEGEFNGRIGVFPSVLVEELSASENGDTPWMREIQISPSPKPHAS 600 610 620 630 640 650 640 650 660 pF1KF0 SPPAPTSVLDGPPAPVLPG-DK--ALDFP---------------GFLDM--MAP-----R :: : . : ::. :. :: .: :: :: . .: . CCDS82 LPPLP--LYDQPPSSPYPSPDKRSSLYFPRSPSANEKSLHAESPGFSQASRHTPETSYGK 660 670 680 690 700 710 670 680 690 pF1KF0 LRPMRPPPPPPAKAPDPGHPDPLT :::.: :::: CCDS82 LRPVRAAPPPPTQNHRRPAEKIEDVEITLV 720 730 740 690 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:33:44 2016 done: Sat Nov 5 06:33:44 2016 Total Scan time: 4.260 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]