FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0040, 1050 aa 1>>>pF1KF0040 1050 - 1050 aa - 1050 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1642+/-0.00126; mu= 12.7688+/- 0.075 mean_var=137.2796+/-28.811, 0's: 0 Z-trim(105.4): 266 B-trim: 15 in 1/50 Lambda= 0.109464 statistics sampled from 8110 (8418) to 8110 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.259), width: 16 Scan time: 3.660 The best scores are: opt bits E(32554) CCDS32986.1 ANKRD27 gene_id:84079|Hs108|chr19 (1050) 6957 1111.6 0 CCDS6746.1 INVS gene_id:27130|Hs108|chr9 (1065) 367 70.9 1.6e-11 >>CCDS32986.1 ANKRD27 gene_id:84079|Hs108|chr19 (1050 aa) initn: 6957 init1: 6957 opt: 6957 Z-score: 5944.8 bits: 1111.6 E(32554): 0 Smith-Waterman score: 6957; 99.8% identity (99.9% similar) in 1050 aa overlap (1-1050:1-1050) 10 20 30 40 50 60 pF1KF0 MALYDEDLLKNPFYLALQKCRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MALYDEDLLKNPFYLALQKCRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 VEEHFQTLNGKDVFIQGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VEEHFQTLNGKDVFIQGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 ESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSANA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 ESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSANA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 LYTKCLQQLLRDSHLKMLAKQEAQMNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAAFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LYTKCLQQLLRDSHLKMLAKQEAQMNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAAFN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 KITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 RVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 YIRQGSLSAKPPESEGFGDRLFLKQRMSLLSQMTSSPTDCLFKHIASGNQKEVERLLSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 YIRQGSLSAKPPESEGFGDRLFLKQRMSLLSQMTSSPTDCLFKHIASGNQKEVERLLSQE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 DHDKDTVQKMCHPLCFCDDCEKLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DHDKDTVQKMCHPLCFCDDCEKLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLID 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 LLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 HEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 HEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKET 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 PLKCALNSKILSVMEAYHLSFERRQKSSEAPVQSPQRSVDSISQESSTSSFSSMSAGSRQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: CCDS32 PLKCALNSKILSVMEAYHLSFERRQKSSEAPVQSPQRSVDSISQESSTSSFSSMSASSRQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KF0 EETKKDYREVEKLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAADPEFCHPLCQCPKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 EETKKDYREVEKLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAADPEFCHPLCQCPKC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KF0 APAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIRLLLKHGANAGARNADQAVP :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: CCDS32 APAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KF0 LHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KF0 NKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 NKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCV 850 860 870 880 890 900 910 920 930 940 950 960 pF1KF0 ASLDDVAETDRKEYVTVKIRKKWNSKLYDLPDEPFTRQFYFVHSAGQFKGKTSREIMARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 ASLDDVAETDRKEYVTVKIRKKWNSKLYDLPDEPFTRQFYFVHSAGQFKGKTSREIMARD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KF0 RSVPNLTEGSLHEPGRQSVTLRQNNLPAQSGSHAAEKGNSDWPERPGLTQTGPGHRRMLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RSVPNLTEGSLHEPGRQSVTLRQNNLPAQSGSHAAEKGNSDWPERPGLTQTGPGHRRMLR 970 980 990 1000 1010 1020 1030 1040 1050 pF1KF0 RHTVEDAVVSQGPEAAGPLSTPQEVSASRS :::::::::::::::::::::::::::::: CCDS32 RHTVEDAVVSQGPEAAGPLSTPQEVSASRS 1030 1040 1050 >>CCDS6746.1 INVS gene_id:27130|Hs108|chr9 (1065 aa) initn: 393 init1: 223 opt: 367 Z-score: 320.3 bits: 70.9 E(32554): 1.6e-11 Smith-Waterman score: 427; 24.9% identity (54.1% similar) in 651 aa overlap (407-1014:24-663) 380 390 400 410 420 430 pF1KF0 FGDRLFLKQRMSLLSQMTSSPTDCLFKHIASGNQKEVERLLSQEDHDKDTVQKMCH-PLC .:.. ..::. .. :: ... . :: CCDS67 MNKSENLLFAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLM 10 20 30 40 50 440 450 460 470 480 490 pF1KF0 FCDDCEKL--VSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATD .: ..: ... :. . :. ....: : ::.:: :. .. ::... : : CCDS67 YCVLADRLDCADALLKAGADVNKTDHSQR--TALHLAAQKGNYRFMKLLLTRRANWMQKD 60 70 80 90 100 110 500 510 520 530 540 550 pF1KF0 YHGATPLHLACQKGYQSVTLLLLHYKASAEV--QDNNGNTPLHLACTYGHEDCVKALVYY . :::::. .. . :::.. : .:: ::.: .: :: . :.. . :: :. . CCDS67 LEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKH 120 130 140 150 160 170 560 570 580 590 600 pF1KF0 DVESCRLDIGNEKGDTPLHIAARWGYQGVIETL--LQNGASTEI----QNRLKETPLKCA : . . : . .: ::: :: ....:. . ..: :: :. .:::. : CCDS67 DSN---IGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFA 180 190 200 210 220 610 620 630 640 650 pF1KF0 L---NSKILSVMEAYH----LSFER--RQKSSEAPVQSPQRSVDSISQESSTSSFSSMSA . : ...:. .:. :.. : : . . . : . ........ : : CCDS67 VADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQ 230 240 250 260 270 280 660 670 680 690 700 pF1KF0 GSR--QEETKKDYREVEKLL----RAVADGDLEMVRYLLEW-----TEEDLEDAEDTVSA :. . ..... :. :.. . :.::: : . : ... :. . : CCDS67 GATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEG-RTSFMWAAGKGSDDVLRTMLSLKSD 290 300 310 320 330 340 710 720 730 740 750 760 pF1KF0 ADPEFCHPLCQCPKCAPAQK-RLAKVP---ASGLGVNVTSQDGSSPLHVAALHGRADLIR : .. : : . ... : .. :..:. .:: : :. :.:. CCDS67 IDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQ 350 360 370 380 390 400 770 780 790 800 810 820 pF1KF0 LLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGG :.: :: . . : :: : :. .: . :.... .:: .: .: ::: : :: CCDS67 TLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGG 410 420 430 440 450 460 830 840 850 860 870 pF1KF0 HHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGA-SVQVLNKRQR-TA . . .:.:....:. : ....: :::: . . .. ...::: .: :. :...: : CCDS67 YINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTP 470 480 490 500 510 520 880 890 900 910 920 930 pF1KF0 VDCA---EQNSKIMELLQVVPSCVASLDDVAETDRKE-YVTVKIRKKW-NSKLYDLPDEP .: : :.. :. .:. .:...:.: . : :.:: . . : . : CCDS67 LDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQ 530 540 550 560 570 580 940 950 960 970 980 990 pF1KF0 FTRQFYFVHSAGQFKGKTSREIMARDRSVPNLTEGSLHE-PGRQSVTLRQNNLPAQSGSH . .. . . : : ... .: :: . .: :. :.: ::. : :. CCDS67 LRKDAAAKKREEENKRKEAEQQKGR-RSPDSCRPQALPCLPSTQDVPSRQSRAP----SK 590 600 610 620 630 640 1000 1010 1020 1030 1040 1050 pF1KF0 AAEKGNSDWPERPGLTQTGPGHRRMLRRHTVEDAVVSQGPEAAGPLSTPQEVSASRS :: .: .. .:: CCDS67 QPPAGNVAQGPEPRDSRGSPGGSLGGALQKEQHVSSDLQGTNSRRPNETAREHSKGQSAC 650 660 670 680 690 700 1050 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:32:47 2016 done: Sat Nov 5 20:32:48 2016 Total Scan time: 3.660 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]