Result of FASTA (omim) for
pF1KF0052
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KF0052, 328 aa
1>>>pF1KF0052 328 - 328 aa - 328 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4439+/-0.000363; mu= -0.4600+/- 0.023
mean_var=267.3772+/-54.055, 0's: 0 Z-trim(122.8): 6 B-trim: 657 in 1/59
Lambda= 0.078435
statistics sampled from 41475 (41487) to 41475 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.486), width: 16
Scan time: 8.970
The best scores are: opt bits E(85289)
NP_071936 (OMIM: 608250) sin3 histone deacetylase ( 328) 2136 254.2 2.8e-67
XP_011536973 (OMIM: 608250) PREDICTED: sin3 histon ( 407) 2136 254.2 3.3e-67
XP_016875306 (OMIM: 608250) PREDICTED: sin3 histon ( 306) 1663 200.6 3.5e-51
XP_016875308 (OMIM: 608250) PREDICTED: sin3 histon ( 257) 1661 200.3 3.6e-51
XP_016875307 (OMIM: 608250) PREDICTED: sin3 histon ( 257) 1661 200.3 3.6e-51
XP_016875309 (OMIM: 608250) PREDICTED: sin3 histon ( 232) 1392 169.8 4.9e-42
>>NP_071936 (OMIM: 608250) sin3 histone deacetylase core (328 aa)
initn: 2136 init1: 2136 opt: 2136 Z-score: 1328.7 bits: 254.2 E(85289): 2.8e-67
Smith-Waterman score: 2136; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328)
10 20 30 40 50 60
pF1KF0 MSAAGLLAPAPAQAGAPPAPEYYPEEDEELESAEDDERSCRGRESDEDTEDASETDLAKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSAAGLLAPAPAQAGAPPAPEYYPEEDEELESAEDDERSCRGRESDEDTEDASETDLAKH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KF0 DEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYKERIRNAELFLQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYKERIRNAELFLQLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KF0 TEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KF0 MTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KF0 LPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVR
250 260 270 280 290 300
310 320
pF1KF0 KTSDSTKMRIYLGQLQRGLFVIRRRSAA
::::::::::::::::::::::::::::
NP_071 KTSDSTKMRIYLGQLQRGLFVIRRRSAA
310 320
>>XP_011536973 (OMIM: 608250) PREDICTED: sin3 histone de (407 aa)
initn: 2136 init1: 2136 opt: 2136 Z-score: 1327.5 bits: 254.2 E(85289): 3.3e-67
Smith-Waterman score: 2136; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:80-407)
10 20 30
pF1KF0 MSAAGLLAPAPAQAGAPPAPEYYPEEDEEL
::::::::::::::::::::::::::::::
XP_011 LPRTLLGRRRVPSAGGRGVRGPRSAAVRGDMSAAGLLAPAPAQAGAPPAPEYYPEEDEEL
50 60 70 80 90 100
40 50 60 70 80 90
pF1KF0 ESAEDDERSCRGRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESAEDDERSCRGRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEG
110 120 130 140 150 160
100 110 120 130 140 150
pF1KF0 TLQEYQKRMKKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLQEYQKRMKKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENL
170 180 190 200 210 220
160 170 180 190 200 210
pF1KF0 IAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYL
230 240 250 260 270 280
220 230 240 250 260 270
pF1KF0 LTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYH
290 300 310 320 330 340
280 290 300 310 320
pF1KF0 KSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
350 360 370 380 390 400
>>XP_016875306 (OMIM: 608250) PREDICTED: sin3 histone de (306 aa)
initn: 1663 init1: 1663 opt: 1663 Z-score: 1039.9 bits: 200.6 E(85289): 3.5e-51
Smith-Waterman score: 1663; 99.2% identity (100.0% similar) in 259 aa overlap (70-328:48-306)
40 50 60 70 80 90
pF1KF0 CRGRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRM
..::::::::::::::::::::::::::::
XP_016 KPSHCLQTEPQPNRFRETKTSLTFSVHPDGKRMYQDKLASLKRQLQQLQEGTLQEYQKRM
20 30 40 50 60 70
100 110 120 130 140 150
pF1KF0 KKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKK
80 90 100 110 120 130
160 170 180 190 200 210
pF1KF0 MIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMED
140 150 160 170 180 190
220 230 240 250 260 270
pF1KF0 LRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLES
200 210 220 230 240 250
280 290 300 310 320
pF1KF0 KDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
260 270 280 290 300
>>XP_016875308 (OMIM: 608250) PREDICTED: sin3 histone de (257 aa)
initn: 1661 init1: 1661 opt: 1661 Z-score: 1039.6 bits: 200.3 E(85289): 3.6e-51
Smith-Waterman score: 1661; 100.0% identity (100.0% similar) in 257 aa overlap (72-328:1-257)
50 60 70 80 90 100
pF1KF0 GRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKK
::::::::::::::::::::::::::::::
XP_016 MYQDKLASLKRQLQQLQEGTLQEYQKRMKK
10 20 30
110 120 130 140 150 160
pF1KF0 LDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMI
40 50 60 70 80 90
170 180 190 200 210 220
pF1KF0 ENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KF0 TLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKD
160 170 180 190 200 210
290 300 310 320
pF1KF0 NQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
220 230 240 250
>>XP_016875307 (OMIM: 608250) PREDICTED: sin3 histone de (257 aa)
initn: 1661 init1: 1661 opt: 1661 Z-score: 1039.6 bits: 200.3 E(85289): 3.6e-51
Smith-Waterman score: 1661; 100.0% identity (100.0% similar) in 257 aa overlap (72-328:1-257)
50 60 70 80 90 100
pF1KF0 GRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKK
::::::::::::::::::::::::::::::
XP_016 MYQDKLASLKRQLQQLQEGTLQEYQKRMKK
10 20 30
110 120 130 140 150 160
pF1KF0 LDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMI
40 50 60 70 80 90
170 180 190 200 210 220
pF1KF0 ENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KF0 TLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKD
160 170 180 190 200 210
290 300 310 320
pF1KF0 NQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
220 230 240 250
>>XP_016875309 (OMIM: 608250) PREDICTED: sin3 histone de (232 aa)
initn: 1392 init1: 1392 opt: 1392 Z-score: 875.7 bits: 169.8 E(85289): 4.9e-42
Smith-Waterman score: 1392; 100.0% identity (100.0% similar) in 215 aa overlap (114-328:18-232)
90 100 110 120 130 140
pF1KF0 LQQLQEGTLQEYQKRMKKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKK
::::::::::::::::::::::::::::::
XP_016 MISRNGTGLQLSGPLVHELFLQLETEQVERNYIKEKKAAVKEFEDKK
10 20 30 40
150 160 170 180 190 200
pF1KF0 VELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPA
50 60 70 80 90 100
210 220 230 240 250 260
pF1KF0 PAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLY
110 120 130 140 150 160
270 280 290 300 310 320
pF1KF0 YDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIR
170 180 190 200 210 220
pF1KF0 RRSAA
:::::
XP_016 RRSAA
230
328 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:05:05 2016 done: Fri Nov 4 20:05:07 2016
Total Scan time: 8.970 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]