FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0137, 1508 aa 1>>>pF1KF0137 1508 - 1508 aa - 1508 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1717+/-0.00105; mu= 14.8647+/- 0.062 mean_var=148.4281+/-31.093, 0's: 0 Z-trim(108.3): 87 B-trim: 0 in 0/50 Lambda= 0.105273 statistics sampled from 10026 (10104) to 10026 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.31), width: 16 Scan time: 4.690 The best scores are: opt bits E(32554) CCDS4330.1 GEMIN5 gene_id:25929|Hs108|chr5 (1508) 10267 1572.7 0 >>CCDS4330.1 GEMIN5 gene_id:25929|Hs108|chr5 (1508 aa) initn: 10267 init1: 10267 opt: 10267 Z-score: 8431.1 bits: 1572.7 E(32554): 0 Smith-Waterman score: 10267; 99.9% identity (100.0% similar) in 1508 aa overlap (1-1508:1-1508) 10 20 30 40 50 60 pF1KF0 MGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 VGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 VKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIID 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 ISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 YLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 SSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 VKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 FWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 PVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 EISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 ASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KF0 DGTAQVWDALREEPLCNFRGHQGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS43 DGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KF0 PQGKKSIELEKKRLSQPKAKPKKKKKPTLRTPVKLESIDGNEEESMKENSGPVENGVSDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PQGKKSIELEKKRLSQPKAKPKKKKKPTLRTPVKLESIDGNEEESMKENSGPVENGVSDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KF0 EGEEQAREPELPCGLAPAVSREPVICTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EGEEQAREPELPCGLAPAVSREPVICTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KF0 KKRKARSLLPLSTSLDHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KKRKARSLLPLSTSLDHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KF0 TLYRMIDIEGKGHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TLYRMIDIEGKGHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KF0 WLWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 WLWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KF0 VLKDLYLSWGTVLERDGHYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VLKDLYLSWGTVLERDGHYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KF0 DELSASLALRCAQELLLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DELSASLALRCAQELLLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KF0 SSSSYHTWNTGTEGPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SSSSYHTWNTGTEGPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KF0 LLHICHDLTLAVLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LLHICHDLTLAVLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KF0 KLGDHQSPATPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KLGDHQSPATPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDT 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KF0 ASTEETDPETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ASTEETDPETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQET 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KF0 LAEMIRQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LAEMIRQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KF0 ANQRMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ANQRMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYR 1450 1460 1470 1480 1490 1500 pF1KF0 RHCQTFCM :::::::: CCDS43 RHCQTFCM 1508 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:25:58 2016 done: Thu Nov 3 18:25:59 2016 Total Scan time: 4.690 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]