FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0162, 705 aa 1>>>pF1KF0162 705 - 705 aa - 705 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5843+/-0.000866; mu= 14.5401+/- 0.053 mean_var=104.5232+/-21.117, 0's: 0 Z-trim(110.0): 23 B-trim: 189 in 1/51 Lambda= 0.125449 statistics sampled from 11257 (11277) to 11257 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.346), width: 16 Scan time: 4.000 The best scores are: opt bits E(32554) CCDS14011.1 L3MBTL2 gene_id:83746|Hs108|chr22 ( 705) 4871 892.4 0 CCDS11581.2 MBTD1 gene_id:54799|Hs108|chr17 ( 628) 2380 441.6 1.7e-123 CCDS13319.1 L3MBTL1 gene_id:26013|Hs108|chr20 ( 772) 703 138.1 4.8e-32 CCDS46602.2 L3MBTL1 gene_id:26013|Hs108|chr20 ( 840) 703 138.1 5.1e-32 CCDS82238.1 L3MBTL4 gene_id:91133|Hs108|chr18 ( 614) 674 132.8 1.5e-30 CCDS11839.2 L3MBTL4 gene_id:91133|Hs108|chr18 ( 623) 674 132.8 1.5e-30 CCDS34538.1 L3MBTL3 gene_id:84456|Hs108|chr6 ( 755) 666 131.4 4.9e-30 CCDS34537.1 L3MBTL3 gene_id:84456|Hs108|chr6 ( 780) 666 131.4 5e-30 CCDS31138.1 SFMBT2 gene_id:57713|Hs108|chr10 ( 894) 504 102.1 3.7e-21 CCDS53304.1 SCMH1 gene_id:22955|Hs108|chr1 ( 648) 471 96.1 1.8e-19 CCDS30688.1 SCMH1 gene_id:22955|Hs108|chr1 ( 660) 467 95.3 3e-19 CCDS461.1 SCMH1 gene_id:22955|Hs108|chr1 ( 591) 463 94.6 4.5e-19 CCDS53301.1 SCMH1 gene_id:22955|Hs108|chr1 ( 577) 458 93.7 8.4e-19 CCDS53302.1 SCMH1 gene_id:22955|Hs108|chr1 ( 599) 458 93.7 8.6e-19 CCDS14185.1 SCML2 gene_id:10389|Hs108|chrX ( 700) 459 93.9 8.6e-19 CCDS2867.1 SFMBT1 gene_id:51460|Hs108|chr3 ( 866) 447 91.8 4.6e-18 >>CCDS14011.1 L3MBTL2 gene_id:83746|Hs108|chr22 (705 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 4766.2 bits: 892.4 E(32554): 0 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 705 aa overlap (1-705:1-705) 10 20 30 40 50 60 pF1KF0 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI 610 620 630 640 650 660 670 680 690 700 pF1KF0 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD ::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 670 680 690 700 >>CCDS11581.2 MBTD1 gene_id:54799|Hs108|chr17 (628 aa) initn: 2534 init1: 1027 opt: 2380 Z-score: 2330.5 bits: 441.6 E(32554): 1.7e-123 Smith-Waterman score: 2393; 57.1% identity (77.5% similar) in 617 aa overlap (26-639:1-596) 10 20 30 40 50 60 pF1KF0 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE .: :::: : . ::: ::: : : CCDS11 MFDGYDS-----CSEDTSSSSSSEESEE------E 10 20 70 80 90 100 110 pF1KF0 AGELPTS-PLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYS .. ::.. :. . . : . . : :.:::::.::.:.::.:::::::::::::::: CCDS11 VAPLPSNLPI-IKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYS 30 40 50 60 70 80 120 130 140 150 160 170 pF1KF0 SNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGF ::::::::::::::::::::::::.: ::..:. . :.: : . . : . . :: CCDS11 SNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQAT--LQNQAKTKAAVSMEGF 90 100 110 120 130 140 180 190 200 210 220 230 pF1KF0 DWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTA .::......:. ::::.::::.:. : :. ....::: :.: ::..:.:::.... : CCDS11 SWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KF0 GYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMK :: .::::::::::.. :::::. :.::.:::: ..: :::::::. :.:.::..:.: CCDS11 GYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVK 210 220 230 240 250 260 300 310 320 330 340 350 pF1KF0 RLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYED ::.:..::: :: :. :::.:::. ::.::::: .. :::.:::..::::::::.::. CCDS11 RLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEE 270 280 290 300 310 320 360 370 380 390 400 410 pF1KF0 G-DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKV . : ::::::: ::::: .:::: .:: .: :::.... . . :. :.:: :: CCDS11 SEDRTDDFWCHMHSPLIHHIGWSRSIGHRFK----RSDITKK---QDGHFDTPPHLFAKV 330 340 350 360 370 420 430 440 450 460 470 pF1KF0 RAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYH . : : ::.:::::::::::::..:::::. ::: ::.::: .::. ..:: :::::: CCDS11 KEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYH 380 390 400 410 420 430 480 490 500 510 520 530 pF1KF0 ASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKV :.: .:::. ::. : ::::::.:: :.: .::..: : ::: .::: : :::::.: CCDS11 ATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRV 440 450 460 470 480 490 540 550 560 570 580 590 pF1KF0 GMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTG :::::::::::::::::::: :..:::: ::::::. ::::::::::::.::::::.::: CCDS11 GMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTG 500 510 520 530 540 550 600 610 620 630 640 650 pF1KF0 YQLQPPVAAEPATPLKAKEATKKK-KKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGA ::::::.. .:. ::: :.: : .:.. . . CCDS11 YQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELLDGEDYNFLQGASDQ 560 570 580 590 600 610 660 670 680 690 700 pF1KF0 RKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD CCDS11 ESNGSANFYIKQEP 620 >>CCDS13319.1 L3MBTL1 gene_id:26013|Hs108|chr20 (772 aa) initn: 622 init1: 330 opt: 703 Z-score: 688.8 bits: 138.1 E(32554): 4.8e-32 Smith-Waterman score: 703; 36.4% identity (63.0% similar) in 357 aa overlap (293-634:208-555) 270 280 290 300 310 320 pF1KF0 GTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHI--KMVESMK :..:: .. . : ::.. . : : CCDS13 PEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQ--KAITAPVSLFQDSQAVTHNK 180 190 200 210 220 230 330 340 350 360 370 pF1KF0 YPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSD-DDFWCHMWSPLIHPVG :. ::.:: .: .. : . .: : : :::: . :: :. ::: . :: :::.: CCDS13 NGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHF-DGYSECHDFWVNANSPDIHPAG 240 250 260 270 280 290 380 390 400 410 420 430 pF1KF0 WSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVP-YLFKKVRAVYTEGGWFEEGMKLEA : ...:: .. . .. ... .:. .:.: .:: . : :. :::::: CCDS13 WFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLG-FQVGMKLEA 300 310 320 330 340 350 440 450 460 470 480 490 pF1KF0 IDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIE .: .: . .:::.: :. :. ... :. : :..: :: : :. .:::. CCDS13 VDRMNPSLVCVASVTDVV-DSRFLVHFDNW--DDTYDYWC-DPSSPYIHPVGWCQKQGKP 360 370 380 390 400 500 510 520 530 540 550 pF1KF0 LTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV ::::. : . ..: ::.:::.: ..:.:. :.. : :.: :.::::::: .: :: : CCDS13 LTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVR-PPHSFLVNMKLEAVDRRNPALIRV 410 420 430 440 450 460 560 570 580 590 600 610 pF1KF0 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAA-EPAT--- :.:. : . ..::::::. :: :.: . :::.:.::: ::. ::::.. ::.. CCDS13 ASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASP 470 480 490 500 510 520 620 630 640 650 660 pF1KF0 ----PLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPG ::. . . . .... .... : CCDS13 GGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRL 530 540 550 560 570 580 >>CCDS46602.2 L3MBTL1 gene_id:26013|Hs108|chr20 (840 aa) initn: 622 init1: 330 opt: 703 Z-score: 688.3 bits: 138.1 E(32554): 5.1e-32 Smith-Waterman score: 703; 36.4% identity (63.0% similar) in 357 aa overlap (293-634:276-623) 270 280 290 300 310 320 pF1KF0 GTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHI--KMVESMK :..:: .. . : ::.. . : : CCDS46 PEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQ--KAITAPVSLFQDSQAVTHNK 250 260 270 280 290 300 330 340 350 360 370 pF1KF0 YPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSD-DDFWCHMWSPLIHPVG :. ::.:: .: .. : . .: : : :::: . :: :. ::: . :: :::.: CCDS46 NGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHF-DGYSECHDFWVNANSPDIHPAG 310 320 330 340 350 360 380 390 400 410 420 430 pF1KF0 WSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVP-YLFKKVRAVYTEGGWFEEGMKLEA : ...:: .. . .. ... .:. .:.: .:: . : :. :::::: CCDS46 WFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLG-FQVGMKLEA 370 380 390 400 410 420 440 450 460 470 480 490 pF1KF0 IDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIE .: .: . .:::.: :. :. ... :. : :..: :: : :. .:::. CCDS46 VDRMNPSLVCVASVTDVV-DSRFLVHFDNW--DDTYDYWC-DPSSPYIHPVGWCQKQGKP 430 440 450 460 470 500 510 520 530 540 550 pF1KF0 LTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV ::::. : . ..: ::.:::.: ..:.:. :.. : :.: :.::::::: .: :: : CCDS46 LTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVR-PPHSFLVNMKLEAVDRRNPALIRV 480 490 500 510 520 530 560 570 580 590 600 610 pF1KF0 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAA-EPAT--- :.:. : . ..::::::. :: :.: . :::.:.::: ::. ::::.. ::.. CCDS46 ASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASP 540 550 560 570 580 590 620 630 640 650 660 pF1KF0 ----PLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPG ::. . . . .... .... : CCDS46 GGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRL 600 610 620 630 640 650 >>CCDS82238.1 L3MBTL4 gene_id:91133|Hs108|chr18 (614 aa) initn: 553 init1: 299 opt: 674 Z-score: 662.0 bits: 132.8 E(32554): 1.5e-30 Smith-Waterman score: 674; 35.7% identity (63.1% similar) in 333 aa overlap (281-604:43-364) 260 270 280 290 300 310 pF1KF0 ENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVD :: . .. .. :. :: .. . . ::. CCDS82 DSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWS-WEWYLKEQ--KAVAAPVE 20 30 40 50 60 320 330 340 350 360 pF1KF0 FHIKMVESMKYP-----FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDD . : ....: :. ::::: .: . : . : : : :::: .. : : CCDS82 LFSK---DQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDGYLSCYD 70 80 90 100 110 120 370 380 390 400 410 420 pF1KF0 FWCHMWSPLIHPVGWSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVPY-LFKKVRAVY :: . :: :::::: ... : ... . :.. .. .. . .: ::.. CCDS82 FWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFRNRSPNG 130 140 150 160 170 180 430 440 450 460 470 480 pF1KF0 TEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSH . :. ::::::.: : . .::::. .. : :.. :. :. :..: ..: CCDS82 PMSKEFQVGMKLEAVDRKNPSLVCVATIADIVED-RLLVHFDNWD--DSYDYWC-DVNSP 190 200 210 220 230 240 490 500 510 520 530 540 pF1KF0 AIFPATFCQKNDIELTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMK . :. .::.: : :.:: . ..:.: .::: :...:.:...:.: : ::: .:: CCDS82 YVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLP-HGFLPNMK 250 260 270 280 290 300 550 560 570 580 590 600 pF1KF0 LEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQL ::.:: .:::: :::. : . ...:::::: .:: ::. .::::.:.:::..::. : CCDS82 LEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPL 310 320 330 340 350 360 610 620 630 640 650 660 pF1KF0 QPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKIS . : CCDS82 EVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRL 370 380 390 400 410 420 >>CCDS11839.2 L3MBTL4 gene_id:91133|Hs108|chr18 (623 aa) initn: 553 init1: 299 opt: 674 Z-score: 661.9 bits: 132.8 E(32554): 1.5e-30 Smith-Waterman score: 674; 35.7% identity (63.1% similar) in 333 aa overlap (281-604:43-364) 260 270 280 290 300 310 pF1KF0 ENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVD :: . .. .. :. :: .. . . ::. CCDS11 DSKERLDQDGRLEQAEEEKKPKDSTTPLSHVPSAAAQGAWS-WEWYLKEQ--KAVAAPVE 20 30 40 50 60 320 330 340 350 360 pF1KF0 FHIKMVESMKYP-----FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDD . : ....: :. ::::: .: . : . : : : :::: .. : : CCDS11 LFSK---DQSFPEHENGFQIGMRLEGIDPRHPSVFCVLSVAEVCGYRLRLHFDGYLSCYD 70 80 90 100 110 120 370 380 390 400 410 420 pF1KF0 FWCHMWSPLIHPVGWSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVPY-LFKKVRAVY :: . :: :::::: ... : ... . :.. .. .. . .: ::.. CCDS11 FWTNAGSPDIHPVGWCEKTKHELHIPKGYRKDKFVWMDYLKACKLQNAPKKLFRNRSPNG 130 140 150 160 170 180 430 440 450 460 470 480 pF1KF0 TEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSH . :. ::::::.: : . .::::. .. : :.. :. :. :..: ..: CCDS11 PMSKEFQVGMKLEAVDRKNPSLVCVATIADIVED-RLLVHFDNWD--DSYDYWC-DVNSP 190 200 210 220 230 240 490 500 510 520 530 540 pF1KF0 AIFPATFCQKNDIELTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMK . :. .::.: : :.:: . ..:.: .::: :...:.:...:.: : ::: .:: CCDS11 YVQPVGWCQENGRTLIAPQGYPNPENFSWTEYLEATQTNAVPAKVFKMRLP-HGFLPNMK 250 260 270 280 290 300 550 560 570 580 590 600 pF1KF0 LEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQL ::.:: .:::: :::. : . ...:::::: .:: ::. .::::.:.:::..::. : CCDS11 LEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPL 310 320 330 340 350 360 610 620 630 640 650 660 pF1KF0 QPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKIS . : CCDS11 EVPQRTNDLKILPGQAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRL 370 380 390 400 410 420 >>CCDS34538.1 L3MBTL3 gene_id:84456|Hs108|chr6 (755 aa) initn: 520 init1: 318 opt: 666 Z-score: 652.8 bits: 131.4 E(32554): 4.9e-30 Smith-Waterman score: 666; 36.5% identity (63.5% similar) in 348 aa overlap (281-620:199-529) 260 270 280 290 300 310 pF1KF0 ENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVD .::. .: : .:: .. . ..:. CCDS34 MENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWC--WASYLEEE--KAVAVPAK 170 180 190 200 210 220 320 330 340 350 360 pF1KF0 FHIKMVESMKYP---FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSD-DDF . .: .:. : :. ::.:: :: . : . .: : : :..: . :: :: :: CCDS34 L-FKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHF-DGYSDCYDF 230 240 250 260 270 280 370 380 390 400 410 420 pF1KF0 WCHMWSPLIHPVGWSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVPY-LFKKVRAVYT : . . :::::: ...:: .. . .. .. . .. .:.: ::.. . CCDS34 WVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVI 290 300 310 320 330 340 430 440 450 460 470 480 pF1KF0 EGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHA .: :. ::::::.: : . :::::: ..:. ... :. .. :..: .::: CCDS34 PSG-FRVGMKLEAVDKKNPSFICVATVTD-MVDNRFLVHFDNW--DESYDYWC-EASSPH 350 360 370 380 390 490 500 510 520 530 540 pF1KF0 IFPATFCQKNDIELTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKL : :. .:... : : :: ... :.:..:::.:.: ::.: :.. : :::. ::: CCDS34 IHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVK-PPHGFQKKMKL 400 410 420 430 440 450 550 560 570 580 590 600 pF1KF0 EAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQ :.:: .: .: :::: . . ...:::::.. :: :.: .::::.::::: ::. :: CCDS34 EVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQ 460 470 480 490 500 510 610 620 630 640 650 660 pF1KF0 PPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISS ::. .::. ::.. CCDS34 PPL-----SPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIF 520 530 540 550 560 570 >>CCDS34537.1 L3MBTL3 gene_id:84456|Hs108|chr6 (780 aa) initn: 520 init1: 318 opt: 666 Z-score: 652.6 bits: 131.4 E(32554): 5e-30 Smith-Waterman score: 666; 36.5% identity (63.5% similar) in 348 aa overlap (281-620:224-554) 260 270 280 290 300 310 pF1KF0 ENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVD .::. .: : .:: .. . ..:. CCDS34 MENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWC--WASYLEEE--KAVAVPAK 200 210 220 230 240 320 330 340 350 360 pF1KF0 FHIKMVESMKYP---FRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSD-DDF . .: .:. : :. ::.:: :: . : . .: : : :..: . :: :: :: CCDS34 L-FKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHF-DGYSDCYDF 250 260 270 280 290 300 370 380 390 400 410 420 pF1KF0 WCHMWSPLIHPVGWSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVPY-LFKKVRAVYT : . . :::::: ...:: .. . .. .. . .. .:.: ::.. . CCDS34 WVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFENQNITVI 310 320 330 340 350 360 430 440 450 460 470 480 pF1KF0 EGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHA .: :. ::::::.: : . :::::: ..:. ... :. .. :..: .::: CCDS34 PSG-FRVGMKLEAVDKKNPSFICVATVTD-MVDNRFLVHFDNW--DESYDYWC-EASSPH 370 380 390 400 410 420 490 500 510 520 530 540 pF1KF0 IFPATFCQKNDIELTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKL : :. .:... : : :: ... :.:..:::.:.: ::.: :.. : :::. ::: CCDS34 IHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVK-PPHGFQKKMKL 430 440 450 460 470 480 550 560 570 580 590 600 pF1KF0 EAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQ :.:: .: .: :::: . . ...:::::.. :: :.: .::::.::::: ::. :: CCDS34 EVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPLQ 490 500 510 520 530 540 610 620 630 640 650 660 pF1KF0 PPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISS ::. .::. ::.. CCDS34 PPL-----SPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIF 550 560 570 580 590 >>CCDS31138.1 SFMBT2 gene_id:57713|Hs108|chr10 (894 aa) initn: 794 init1: 326 opt: 504 Z-score: 493.3 bits: 102.1 E(32554): 3.7e-21 Smith-Waterman score: 908; 34.2% identity (61.2% similar) in 497 aa overlap (158-636:25-500) 130 140 150 160 170 180 pF1KF0 LARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDWGKFLKD ..:.:.: . :.. ::.::..:.. CCDS31 MESTLSASNMQDPSSSPLEKCLGSANGNGDL--DSEEGSSLEETGFNWGEYLEE 10 20 30 40 50 190 200 210 220 230 240 pF1KF0 HSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGYRVLLRY . .::: . :::: . : . . :::.:: :.. :. .::.:..: : : .:::: CCDS31 TGASAAPHTSFKHVEISIQ-SNFQPGMKLEVANKNN--PD-TYWVATIITTCGQLLLLRY 60 70 80 90 100 250 260 270 280 290 300 pF1KF0 EGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTL :. .: ::::.. .:.::.:::. :.:.:.:: .:. :.::: .:.. :.:::: CCDS31 CGYGEDRRADFWCDVVIADLHPVGWCTQNNKVLMPPDAIKEKYTDWTEFLIRDLTGSRTA 110 120 130 140 150 160 310 320 330 340 350 360 pF1KF0 PVDFHIKMVESMKYPFRQ---GMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLY---EDGD :... .. : :. : .:. :... . .. : .:::::: : :: . CCDS31 PANL-LEGPLRGKGPIDLITVGSLIELQDSQNPFQYWIVSVIENVGGRLRLRYVGLEDTE 170 180 190 200 210 220 370 380 390 400 410 pF1KF0 SDDDFWCHMWSPLIHPVGWSR----RVGHGIKMSERRSDMAHHPTFRKIYCDAVPY---- : :. : . . ..:::: . :. .. . . :..: ::. . CCDS31 SYDQ-WLFYLDYRLRPVGWCQENKYRMDPPSEIYPLKMASEWKCTLEKSLIDAAKFPLPM 230 240 250 260 270 280 420 430 440 450 460 470 pF1KF0 -LFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDG-GPSTDG .:: . .. .: :::::... . : :.: ::. . .... .: : . CCDS31 EVFKDHADLRSH--FFTVGMKLETVNMCEPFYISPASVTKVFNNHFFQVTIDDLRPEPSK 290 300 310 320 330 340 480 490 500 510 520 530 pF1KF0 LDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDC :. .: ::.: .:.:. .: :: . ::::::: .: :.: .: .. .. :: : CCDS31 LSMLC-HADSLGILPVQWCLKNGVSLTPPKGYSGQDFDWADYHKQHGAQEAPPFCFRNTS 350 360 370 380 390 400 540 550 560 570 580 590 pF1KF0 PNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQW-VDCESPDIYP ..:: .::::::. .: .:::.: : ::. .:..: .. . :: :: ::.: CCDS31 FSRGFTKNMKLEAVNPRNPGELCVASVVSVKGRLMWLHLEGLQTPVPEVIVDVESMDIFP 410 420 430 440 450 460 600 610 620 630 640 pF1KF0 VGWCELTGYQLQPPVAAEPATPLKAKEATKKKKK-QFGKKRKRIPPTKTRPLRQGSKKPL ::::: ..: : : : ...::.: . .:..::: CCDS31 VGWCEANSYPLTAP----------HKTVSQKKRKIAVVQPEKQLPPTVPVKKIPHDLCLF 470 480 490 500 510 650 660 670 680 690 700 pF1KF0 LEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD CCDS31 PHLDTTGTVNGKYCCPQLFINHRCFSGPYLNKGRIAELPQSVGPGKCVLVLKEVLSMIIN 520 530 540 550 560 570 >>CCDS53304.1 SCMH1 gene_id:22955|Hs108|chr1 (648 aa) initn: 435 init1: 269 opt: 471 Z-score: 463.0 bits: 96.1 E(32554): 1.8e-19 Smith-Waterman score: 476; 32.5% identity (54.5% similar) in 332 aa overlap (396-696:34-359) 370 380 390 400 410 420 pF1KF0 FWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHP--TFRKIYCDAVPYLFKKVRAVYT :..: . : : .:: . . :: CCDS53 NVIDWSDVRKHKYGHLSESASQYQEAADILDLGHFTWDKYLKETC-SVPAPVHCFKQSYT 10 20 30 40 50 60 430 440 450 460 470 480 pF1KF0 E-GGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSH .. :. .::::: :: : . :.::: : . : . .:: .:. . : ..: CCDS53 PPSNEFKISMKLEAQDPRNTTSTCIATVVG-LTGARLRLRLDG---SDNKNDFWRLVDSA 70 80 90 100 110 490 500 510 520 530 pF1KF0 AIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKA--APSRLFNMD--CPNHGF-K : : :.:: : :: :.. .. .: .: :: . : :: :.:. . :.:.: : CCDS53 EIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFK 120 130 140 150 160 170 540 550 560 570 580 590 pF1KF0 VGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELT .:::::::: .:..:: ::. .: . . :::: . .: : .: ::.::::: :: CCDS53 MGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLT 180 190 200 210 220 230 600 610 620 630 pF1KF0 GYQLQPP--VAAEPATPLKAKEATKKKK------------------KQFGKKRKRIPPTK : .:::: .. : .: :.... .: .. :::: : : : CCDS53 GDNLQPPGTKVVIPKNPYPASDVNTEKPSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTL 240 250 260 270 280 290 640 650 660 670 680 690 pF1KF0 -TRPLRQGSK--KPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPV ..:. :: .:: .: : .:. : .. .. :: .. :. . CCDS53 ISHPISAPSKTAEPLKFPKKRGP-KPGSKRKPRTLLNPPPASPTTSTPEPDTSTVPQDAA 300 310 320 330 340 350 700 pF1KF0 SVENIKQETDD .. CCDS53 TIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHFGPARASVVLQQAVQACIDCAYH 360 370 380 390 400 410 705 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:07:02 2016 done: Fri Nov 4 20:07:02 2016 Total Scan time: 4.000 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]