FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0162, 705 aa 1>>>pF1KF0162 705 - 705 aa - 705 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2242+/-0.000335; mu= 16.6549+/- 0.021 mean_var=106.9228+/-21.430, 0's: 0 Z-trim(117.2): 78 B-trim: 0 in 0/56 Lambda= 0.124034 statistics sampled from 28821 (28903) to 28821 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.339), width: 16 Scan time: 11.790 The best scores are: opt bits E(85289) NP_113676 (OMIM: 611865) lethal(3)malignant brain ( 705) 4871 882.7 0 XP_011528723 (OMIM: 611865) PREDICTED: lethal(3)ma ( 614) 4273 775.6 0 XP_011528722 (OMIM: 611865) PREDICTED: lethal(3)ma ( 687) 4014 729.3 1.2e-209 XP_016884466 (OMIM: 611865) PREDICTED: lethal(3)ma ( 595) 3538 644.1 4.7e-184 XP_016884468 (OMIM: 611865) PREDICTED: lethal(3)ma ( 495) 3455 629.2 1.2e-179 XP_016884467 (OMIM: 611865) PREDICTED: lethal(3)ma ( 495) 3455 629.2 1.2e-179 XP_016884465 (OMIM: 611865) PREDICTED: lethal(3)ma ( 621) 3267 595.6 1.9e-169 XP_016884469 (OMIM: 611865) PREDICTED: lethal(3)ma ( 408) 2845 519.9 7.4e-147 NP_056293 (OMIM: 608802) lethal(3)malignant brain ( 772) 703 136.9 2.9e-31 NP_115479 (OMIM: 608802) lethal(3)malignant brain ( 840) 703 136.9 3.1e-31 XP_016881566 (OMIM: 617135) PREDICTED: lethal(3)ma ( 370) 684 133.2 1.8e-30 XP_006722427 (OMIM: 617135) PREDICTED: lethal(3)ma ( 485) 674 131.5 7.5e-30 XP_016881564 (OMIM: 617135) PREDICTED: lethal(3)ma ( 488) 674 131.5 7.5e-30 XP_016881565 (OMIM: 617135) PREDICTED: lethal(3)ma ( 488) 674 131.5 7.5e-30 XP_011524067 (OMIM: 617135) PREDICTED: lethal(3)ma ( 497) 674 131.5 7.6e-30 XP_011524065 (OMIM: 617135) PREDICTED: lethal(3)ma ( 521) 674 131.5 7.9e-30 XP_011524064 (OMIM: 617135) PREDICTED: lethal(3)ma ( 567) 674 131.6 8.4e-30 XP_016881563 (OMIM: 617135) PREDICTED: lethal(3)ma ( 574) 674 131.6 8.5e-30 NP_001317488 (OMIM: 617135) lethal(3)malignant bra ( 614) 674 131.6 9e-30 XP_011524063 (OMIM: 617135) PREDICTED: lethal(3)ma ( 623) 674 131.6 9.1e-30 NP_775735 (OMIM: 617135) lethal(3)malignant brain ( 623) 674 131.6 9.1e-30 XP_011524062 (OMIM: 617135) PREDICTED: lethal(3)ma ( 642) 674 131.6 9.3e-30 XP_011524061 (OMIM: 617135) PREDICTED: lethal(3)ma ( 651) 674 131.6 9.4e-30 XP_011524060 (OMIM: 617135) PREDICTED: lethal(3)ma ( 651) 674 131.6 9.4e-30 XP_011524059 (OMIM: 617135) PREDICTED: lethal(3)ma ( 651) 674 131.6 9.4e-30 XP_016871955 (OMIM: 615392) PREDICTED: scm-like wi ( 894) 504 101.3 1.7e-20 NP_001025051 (OMIM: 615392) scm-like with four MBT ( 894) 504 101.3 1.7e-20 XP_011517913 (OMIM: 615392) PREDICTED: scm-like wi ( 894) 504 101.3 1.7e-20 NP_001018049 (OMIM: 615392) scm-like with four MBT ( 894) 504 101.3 1.7e-20 XP_011539342 (OMIM: 616396) PREDICTED: polycomb pr ( 523) 471 95.2 6.8e-19 XP_006717553 (OMIM: 615392) PREDICTED: scm-like wi ( 725) 472 95.5 7.8e-19 XP_011539336 (OMIM: 616396) PREDICTED: polycomb pr ( 621) 471 95.3 7.8e-19 NP_001165690 (OMIM: 616396) polycomb protein SCMH1 ( 648) 471 95.3 8.1e-19 XP_011539334 (OMIM: 616396) PREDICTED: polycomb pr ( 670) 471 95.3 8.3e-19 XP_006710525 (OMIM: 616396) PREDICTED: polycomb pr ( 670) 471 95.3 8.3e-19 XP_016856187 (OMIM: 616396) PREDICTED: polycomb pr ( 618) 467 94.6 1.3e-18 NP_001026864 (OMIM: 616396) polycomb protein SCMH1 ( 660) 467 94.6 1.3e-18 XP_011539335 (OMIM: 616396) PREDICTED: polycomb pr ( 660) 467 94.6 1.3e-18 XP_016856189 (OMIM: 616396) PREDICTED: polycomb pr ( 564) 463 93.8 2e-18 NP_036368 (OMIM: 616396) polycomb protein SCMH1 is ( 591) 463 93.8 2e-18 XP_011539337 (OMIM: 616396) PREDICTED: polycomb pr ( 613) 463 93.8 2.1e-18 XP_006724521 (OMIM: 300208) PREDICTED: sex comb on ( 609) 459 93.1 3.4e-18 XP_016884710 (OMIM: 300208) PREDICTED: sex comb on ( 609) 459 93.1 3.4e-18 NP_001165691 (OMIM: 616396) polycomb protein SCMH1 ( 577) 458 92.9 3.7e-18 NP_001165689 (OMIM: 616396) polycomb protein SCMH1 ( 577) 458 92.9 3.7e-18 XP_016884708 (OMIM: 300208) PREDICTED: sex comb on ( 700) 459 93.2 3.8e-18 NP_006080 (OMIM: 300208) sex comb on midleg-like p ( 700) 459 93.2 3.8e-18 XP_016884709 (OMIM: 300208) PREDICTED: sex comb on ( 700) 459 93.2 3.8e-18 XP_016856188 (OMIM: 616396) PREDICTED: polycomb pr ( 599) 458 92.9 3.8e-18 XP_006710527 (OMIM: 616396) PREDICTED: polycomb pr ( 599) 458 92.9 3.8e-18 >>NP_113676 (OMIM: 611865) lethal(3)malignant brain tumo (705 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 4713.5 bits: 882.7 E(85289): 0 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 705 aa overlap (1-705:1-705) 10 20 30 40 50 60 pF1KF0 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_113 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI 610 620 630 640 650 660 670 680 690 700 pF1KF0 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD ::::::::::::::::::::::::::::::::::::::::::::: NP_113 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 670 680 690 700 >>XP_011528723 (OMIM: 611865) PREDICTED: lethal(3)malign (614 aa) initn: 4273 init1: 4273 opt: 4273 Z-score: 4136.0 bits: 775.6 E(85289): 0 Smith-Waterman score: 4273; 100.0% identity (100.0% similar) in 614 aa overlap (92-705:1-614) 70 80 90 100 110 120 pF1KF0 GELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSN :::::::::::::::::::::::::::::: XP_011 MCGIVGTREAFFSKTKRFCSVSCSRSYSSN 10 20 30 130 140 150 160 170 180 pF1KF0 SKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFDW 40 50 60 70 80 90 190 200 210 220 230 240 pF1KF0 GKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAGY 100 110 120 130 140 150 250 260 270 280 290 300 pF1KF0 RVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRL 160 170 180 190 200 210 310 320 330 340 350 360 pF1KF0 VGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGD 220 230 240 250 260 270 370 380 390 400 410 420 pF1KF0 SDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRAV 280 290 300 310 320 330 430 440 450 460 470 480 pF1KF0 YTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASS 340 350 360 370 380 390 490 500 510 520 530 540 pF1KF0 HAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMK 400 410 420 430 440 450 550 560 570 580 590 600 pF1KF0 LEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQL 460 470 480 490 500 510 610 620 630 640 650 660 pF1KF0 QPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKIS 520 530 540 550 560 570 670 680 690 700 pF1KF0 SEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD :::::::::::::::::::::::::::::::::::::::::::: XP_011 SEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 580 590 600 610 >>XP_011528722 (OMIM: 611865) PREDICTED: lethal(3)malign (687 aa) initn: 4014 init1: 4014 opt: 4014 Z-score: 3884.9 bits: 729.3 E(85289): 1.2e-209 Smith-Waterman score: 4014; 100.0% identity (100.0% similar) in 574 aa overlap (132-705:114-687) 110 120 130 140 150 160 pF1KF0 FFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGT :::::::::::::::::::::::::::::: XP_011 RIGKQGNCRPPRCICSALGLLAPWMAVVLSQGKPPTKKAKVLHKAAWSAKIGAFLHSQGT 90 100 110 120 130 140 170 180 190 200 210 220 pF1KF0 GQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNS 150 160 170 180 190 200 230 240 250 260 270 280 pF1KF0 DAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAVLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILV 210 220 230 240 250 260 290 300 310 320 330 340 pF1KF0 PPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTR 270 280 290 300 310 320 350 360 370 380 390 400 pF1KF0 MAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHP 330 340 350 360 370 380 410 420 430 440 450 460 pF1KF0 TFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMI 390 400 410 420 430 440 470 480 490 500 510 520 pF1KF0 CVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKA 450 460 470 480 490 500 530 540 550 560 570 580 pF1KF0 APSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWV 510 520 530 540 550 560 590 600 610 620 630 640 pF1KF0 DCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPL 570 580 590 600 610 620 650 660 670 680 690 700 pF1KF0 RQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQ 630 640 650 660 670 680 pF1KF0 ETDD :::: XP_011 ETDD >>XP_016884466 (OMIM: 611865) PREDICTED: lethal(3)malign (595 aa) initn: 3538 init1: 3538 opt: 3538 Z-score: 3425.4 bits: 644.1 E(85289): 4.7e-184 Smith-Waterman score: 3544; 90.9% identity (93.4% similar) in 572 aa overlap (136-705:43-595) 110 120 130 140 150 160 pF1KF0 TKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAW-SAKIGAFLHSQGTGQL : .: : :: :: ...: .... XP_016 GSLFFALNSLIVSAFSFPGSCIILVSNTYNPICFVKSLPLRAWASATVSGFCDELNSSDQ 20 30 40 50 60 70 170 180 190 200 210 220 pF1KF0 ADGTPTGQDALVLGF-DWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDA .:: .:. .: : : .:.::::::::::::::::::::::: XP_016 GDG---------MGYLNWLK----------PGLRIKKVPLYDQWEDVMKGMKVEVLNSDA 80 90 100 110 230 240 250 260 270 280 pF1KF0 VLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPSRVYWIASVIQTAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPP 120 130 140 150 160 170 290 300 310 320 330 340 pF1KF0 RTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMA 180 190 200 210 220 230 350 360 370 380 390 400 pF1KF0 VVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTF 240 250 260 270 280 290 410 420 430 440 450 460 pF1KF0 RKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICV 300 310 320 330 340 350 470 480 490 500 510 520 pF1KF0 DGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAP 360 370 380 390 400 410 530 540 550 560 570 580 pF1KF0 SRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDC 420 430 440 450 460 470 590 600 610 620 630 640 pF1KF0 ESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQ 480 490 500 510 520 530 650 660 670 680 690 700 pF1KF0 GSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQET 540 550 560 570 580 590 pF1KF0 DD :: XP_016 DD >>XP_016884468 (OMIM: 611865) PREDICTED: lethal(3)malign (495 aa) initn: 3455 init1: 3455 opt: 3455 Z-score: 3346.3 bits: 629.2 E(85289): 1.2e-179 Smith-Waterman score: 3455; 100.0% identity (100.0% similar) in 495 aa overlap (211-705:1-495) 190 200 210 220 230 240 pF1KF0 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG :::::::::::::::::::::::::::::: XP_016 MKGMKVEVLNSDAVLPSRVYWIASVIQTAG 10 20 30 250 260 270 280 290 300 pF1KF0 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR 40 50 60 70 80 90 310 320 330 340 350 360 pF1KF0 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG 100 110 120 130 140 150 370 380 390 400 410 420 pF1KF0 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA 160 170 180 190 200 210 430 440 450 460 470 480 pF1KF0 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS 220 230 240 250 260 270 490 500 510 520 530 540 pF1KF0 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM 280 290 300 310 320 330 550 560 570 580 590 600 pF1KF0 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ 340 350 360 370 380 390 610 620 630 640 650 660 pF1KF0 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI 400 410 420 430 440 450 670 680 690 700 pF1KF0 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD ::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 460 470 480 490 >>XP_016884467 (OMIM: 611865) PREDICTED: lethal(3)malign (495 aa) initn: 3455 init1: 3455 opt: 3455 Z-score: 3346.3 bits: 629.2 E(85289): 1.2e-179 Smith-Waterman score: 3455; 100.0% identity (100.0% similar) in 495 aa overlap (211-705:1-495) 190 200 210 220 230 240 pF1KF0 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG :::::::::::::::::::::::::::::: XP_016 MKGMKVEVLNSDAVLPSRVYWIASVIQTAG 10 20 30 250 260 270 280 290 300 pF1KF0 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR 40 50 60 70 80 90 310 320 330 340 350 360 pF1KF0 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG 100 110 120 130 140 150 370 380 390 400 410 420 pF1KF0 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA 160 170 180 190 200 210 430 440 450 460 470 480 pF1KF0 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS 220 230 240 250 260 270 490 500 510 520 530 540 pF1KF0 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM 280 290 300 310 320 330 550 560 570 580 590 600 pF1KF0 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ 340 350 360 370 380 390 610 620 630 640 650 660 pF1KF0 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI 400 410 420 430 440 450 670 680 690 700 pF1KF0 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD ::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 460 470 480 490 >>XP_016884465 (OMIM: 611865) PREDICTED: lethal(3)malign (621 aa) initn: 3822 init1: 3267 opt: 3267 Z-score: 3163.1 bits: 595.6 E(85289): 1.9e-169 Smith-Waterman score: 3691; 80.4% identity (85.1% similar) in 705 aa overlap (1-705:1-621) 10 20 30 40 50 60 pF1KF0 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS :::::::::::::::::::::::::::. :: . . :. XP_016 AGELPTSPLHLLSPGTPRSLDGSGSEPG----------------KT--------TDQKSQ 70 80 90 130 140 150 160 170 180 pF1KF0 NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD . .. .. . . :: .. .. . :... ... .: ::. XP_016 SPAQGCLVCQNWSLPPLSRDRTAGR--WDTN-----RTRRSG--------------LGLR 100 110 120 130 190 200 210 220 230 240 pF1KF0 WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG :. :: .: ..: . .... : XP_016 LGE-----------------VPEGSQ----LQGCSRQLFQ------------------AR 140 150 250 260 270 280 290 300 pF1KF0 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR 160 170 180 190 200 210 310 320 330 340 350 360 pF1KF0 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG 220 230 240 250 260 270 370 380 390 400 410 420 pF1KF0 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA 280 290 300 310 320 330 430 440 450 460 470 480 pF1KF0 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS 340 350 360 370 380 390 490 500 510 520 530 540 pF1KF0 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM 400 410 420 430 440 450 550 560 570 580 590 600 pF1KF0 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ 460 470 480 490 500 510 610 620 630 640 650 660 pF1KF0 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI 520 530 540 550 560 570 670 680 690 700 pF1KF0 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD ::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD 580 590 600 610 620 >>XP_016884469 (OMIM: 611865) PREDICTED: lethal(3)malign (408 aa) initn: 2845 init1: 2845 opt: 2845 Z-score: 2757.5 bits: 519.9 E(85289): 7.4e-147 Smith-Waterman score: 2845; 100.0% identity (100.0% similar) in 408 aa overlap (298-705:1-408) 270 280 290 300 310 320 pF1KF0 HPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHIKMVESMKYPFRQGM :::::::::::::::::::::::::::::: XP_016 MKRLVGSRTLPVDFHIKMVESMKYPFRQGM 10 20 30 330 340 350 360 370 380 pF1KF0 RLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHG 40 50 60 70 80 90 390 400 410 420 430 440 pF1KF0 IKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICV 100 110 120 130 140 150 450 460 470 480 490 500 pF1KF0 ATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIELTPPKGYEAQT 160 170 180 190 200 210 510 520 530 540 550 560 pF1KF0 FNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLS 220 230 240 250 260 270 570 580 590 600 610 620 pF1KF0 IHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAAEPATPLKAKEATKKKKKQFG 280 290 300 310 320 330 630 640 650 660 670 680 pF1KF0 KKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKA 340 350 360 370 380 390 690 700 pF1KF0 SSPELPVSVENIKQETDD :::::::::::::::::: XP_016 SSPELPVSVENIKQETDD 400 >>NP_056293 (OMIM: 608802) lethal(3)malignant brain tumo (772 aa) initn: 622 init1: 330 opt: 703 Z-score: 682.2 bits: 136.9 E(85289): 2.9e-31 Smith-Waterman score: 703; 36.4% identity (63.0% similar) in 357 aa overlap (293-634:208-555) 270 280 290 300 310 320 pF1KF0 GTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHI--KMVESMK :..:: .. . : ::.. . : : NP_056 PEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQ--KAITAPVSLFQDSQAVTHNK 180 190 200 210 220 230 330 340 350 360 370 pF1KF0 YPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSD-DDFWCHMWSPLIHPVG :. ::.:: .: .. : . .: : : :::: . :: :. ::: . :: :::.: NP_056 NGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHF-DGYSECHDFWVNANSPDIHPAG 240 250 260 270 280 290 380 390 400 410 420 430 pF1KF0 WSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVP-YLFKKVRAVYTEGGWFEEGMKLEA : ...:: .. . .. ... .:. .:.: .:: . : :. :::::: NP_056 WFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLG-FQVGMKLEA 300 310 320 330 340 350 440 450 460 470 480 490 pF1KF0 IDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIE .: .: . .:::.: :. :. ... :. : :..: :: : :. .:::. NP_056 VDRMNPSLVCVASVTDVV-DSRFLVHFDNW--DDTYDYWC-DPSSPYIHPVGWCQKQGKP 360 370 380 390 400 500 510 520 530 540 550 pF1KF0 LTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV ::::. : . ..: ::.:::.: ..:.:. :.. : :.: :.::::::: .: :: : NP_056 LTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVR-PPHSFLVNMKLEAVDRRNPALIRV 410 420 430 440 450 460 560 570 580 590 600 610 pF1KF0 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAA-EPAT--- :.:. : . ..::::::. :: :.: . :::.:.::: ::. ::::.. ::.. NP_056 ASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASP 470 480 490 500 510 520 620 630 640 650 660 pF1KF0 ----PLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPG ::. . . . .... .... : NP_056 GGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRL 530 540 550 560 570 580 >>NP_115479 (OMIM: 608802) lethal(3)malignant brain tumo (840 aa) initn: 622 init1: 330 opt: 703 Z-score: 681.7 bits: 136.9 E(85289): 3.1e-31 Smith-Waterman score: 703; 36.4% identity (63.0% similar) in 357 aa overlap (293-634:276-623) 270 280 290 300 310 320 pF1KF0 GTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKRLVGSRTLPVDFHI--KMVESMK :..:: .. . : ::.. . : : NP_115 PEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQ--KAITAPVSLFQDSQAVTHNK 250 260 270 280 290 300 330 340 350 360 370 pF1KF0 YPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDGDSD-DDFWCHMWSPLIHPVG :. ::.:: .: .. : . .: : : :::: . :: :. ::: . :: :::.: NP_115 NGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHF-DGYSECHDFWVNANSPDIHPAG 310 320 330 340 350 360 380 390 400 410 420 430 pF1KF0 WSRRVGHGIKMSE--RRSDMAHHPTFRKIYCDAVP-YLFKKVRAVYTEGGWFEEGMKLEA : ...:: .. . .. ... .:. .:.: .:: . : :. :::::: NP_115 WFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLG-FQVGMKLEA 370 380 390 400 410 420 440 450 460 470 480 490 pF1KF0 IDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHASSHAIFPATFCQKNDIE .: .: . .:::.: :. :. ... :. : :..: :: : :. .:::. NP_115 VDRMNPSLVCVASVTDVV-DSRFLVHFDNW--DDTYDYWC-DPSSPYIHPVGWCQKQGKP 430 440 450 460 470 500 510 520 530 540 550 pF1KF0 LTPPKGY-EAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGMKLEAVDLMEPRLICV ::::. : . ..: ::.:::.: ..:.:. :.. : :.: :.::::::: .: :: : NP_115 LTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVR-PPHSFLVNMKLEAVDRRNPALIRV 480 490 500 510 520 530 560 570 580 590 600 610 pF1KF0 ATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQLQPPVAA-EPAT--- :.:. : . ..::::::. :: :.: . :::.:.::: ::. ::::.. ::.. NP_115 ASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPREPSSASP 540 550 560 570 580 590 620 630 640 650 660 pF1KF0 ----PLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPG ::. . . . .... .... : NP_115 GGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRL 600 610 620 630 640 650 705 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:07:03 2016 done: Fri Nov 4 20:07:04 2016 Total Scan time: 11.790 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]