FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0165, 270 aa 1>>>pF1KF0165 270 - 270 aa - 270 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3153+/-0.00026; mu= 17.3654+/- 0.016 mean_var=91.3322+/-18.282, 0's: 0 Z-trim(122.5): 8 B-trim: 0 in 0/51 Lambda= 0.134203 statistics sampled from 40619 (40631) to 40619 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.807), E-opt: 0.2 (0.476), width: 16 Scan time: 7.880 The best scores are: opt bits E(85289) NP_666017 (OMIM: 608740) NFAT activation molecule ( 270) 1864 369.8 2.9e-102 XP_005261431 (OMIM: 608740) PREDICTED: NFAT activa ( 218) 1496 298.5 7e-81 NP_001305252 (OMIM: 608740) NFAT activation molecu ( 198) 1075 216.9 2.3e-56 >>NP_666017 (OMIM: 608740) NFAT activation molecule 1 is (270 aa) initn: 1864 init1: 1864 opt: 1864 Z-score: 1956.9 bits: 369.8 E(85289): 2.9e-102 Smith-Waterman score: 1864; 100.0% identity (100.0% similar) in 270 aa overlap (1-270:1-270) 10 20 30 40 50 60 pF1KF0 MENQPVRWRALPGLPRPPGLPAAPWLLLGVLLLPGTLRLAGGQSVTHTGLPIMASLANTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 MENQPVRWRALPGLPRPPGLPAAPWLLLGVLLLPGTLRLAGGQSVTHTGLPIMASLANTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 ISFSCRITYPYTPQFKVFTVSYFHEDLQGQRSPKKPTNCHPGLGTENQSHTLDCQVTLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 ISFSCRITYPYTPQFKVFTVSYFHEDLQGQRSPKKPTNCHPGLGTENQSHTLDCQVTLVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 PGASATGTYYCSVHWPHSTVRGSGTFILVRDAGYREPPQSPQKLLLFGFTGLLSVLSVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 PGASATGTYYCSVHWPHSTVRGSGTFILVRDAGYREPPQSPQKLLLFGFTGLLSVLSVVG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 TALLLWNKKRMRGPGKDPTRKCPDPRSASSPKQHPSESVYTALQRRETEVYACIENEDGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_666 TALLLWNKKRMRGPGKDPTRKCPDPRSASSPKQHPSESVYTALQRRETEVYACIENEDGS 190 200 210 220 230 240 250 260 270 pF1KF0 SPTAKQSPLSQERPHRFEDDGELNLVYENL :::::::::::::::::::::::::::::: NP_666 SPTAKQSPLSQERPHRFEDDGELNLVYENL 250 260 270 >>XP_005261431 (OMIM: 608740) PREDICTED: NFAT activation (218 aa) initn: 1496 init1: 1496 opt: 1496 Z-score: 1573.0 bits: 298.5 E(85289): 7e-81 Smith-Waterman score: 1496; 100.0% identity (100.0% similar) in 218 aa overlap (53-270:1-218) 30 40 50 60 70 80 pF1KF0 APWLLLGVLLLPGTLRLAGGQSVTHTGLPIMASLANTAISFSCRITYPYTPQFKVFTVSY :::::::::::::::::::::::::::::: XP_005 MASLANTAISFSCRITYPYTPQFKVFTVSY 10 20 30 90 100 110 120 130 140 pF1KF0 FHEDLQGQRSPKKPTNCHPGLGTENQSHTLDCQVTLVLPGASATGTYYCSVHWPHSTVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FHEDLQGQRSPKKPTNCHPGLGTENQSHTLDCQVTLVLPGASATGTYYCSVHWPHSTVRG 40 50 60 70 80 90 150 160 170 180 190 200 pF1KF0 SGTFILVRDAGYREPPQSPQKLLLFGFTGLLSVLSVVGTALLLWNKKRMRGPGKDPTRKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGTFILVRDAGYREPPQSPQKLLLFGFTGLLSVLSVVGTALLLWNKKRMRGPGKDPTRKC 100 110 120 130 140 150 210 220 230 240 250 260 pF1KF0 PDPRSASSPKQHPSESVYTALQRRETEVYACIENEDGSSPTAKQSPLSQERPHRFEDDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDPRSASSPKQHPSESVYTALQRRETEVYACIENEDGSSPTAKQSPLSQERPHRFEDDGE 160 170 180 190 200 210 270 pF1KF0 LNLVYENL :::::::: XP_005 LNLVYENL >>NP_001305252 (OMIM: 608740) NFAT activation molecule 1 (198 aa) initn: 1110 init1: 1055 opt: 1075 Z-score: 1133.1 bits: 216.9 E(85289): 2.3e-56 Smith-Waterman score: 1075; 96.9% identity (97.5% similar) in 161 aa overlap (1-159:1-161) 10 20 30 40 50 60 pF1KF0 MENQPVRWRALPGLPRPPGLPAAPWLLLGVLLLPGTLRLAGGQSVTHTGLPIMASLANTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MENQPVRWRALPGLPRPPGLPAAPWLLLGVLLLPGTLRLAGGQSVTHTGLPIMASLANTA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 ISFSCRITYPYTPQFKVFTVSYFHEDLQGQRSPKKPTNCHPGLGTENQSHTLDCQVTLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFSCRITYPYTPQFKVFTVSYFHEDLQGQRSPKKPTNCHPGLGTENQSHTLDCQVTLVL 70 80 90 100 110 120 130 140 150 160 170 pF1KF0 PGASATGTYYCSVHWPHSTVRGSGTFILVR--DAGYREPPQSPQKLLLFGFTGLLSVLSV :::::::::::::::::::::::::::::: ::: :: :. NP_001 PGASATGTYYCSVHWPHSTVRGSGTFILVREADAGSREGPHQEVPRSKICQQPQAASFRI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KF0 VGTALLLWNKKRMRGPGKDPTRKCPDPRSASSPKQHPSESVYTALQRRETEVYACIENED NP_001 CLHSSAAPRDRGLCLHRE 190 270 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:07:38 2016 done: Fri Nov 4 20:07:39 2016 Total Scan time: 7.880 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]