FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0188, 1277 aa 1>>>pF1KF0188 1277 - 1277 aa - 1277 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.1961+/-0.000474; mu= -5.0083+/- 0.029 mean_var=341.3325+/-69.066, 0's: 0 Z-trim(120.1): 237 B-trim: 140 in 2/52 Lambda= 0.069420 statistics sampled from 34577 (34885) to 34577 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.409), width: 16 Scan time: 13.100 The best scores are: opt bits E(85289) NP_001159743 (OMIM: 613324) spermatogenesis-associ (1277) 8684 885.0 0 NP_001273721 (OMIM: 613324) spermatogenesis-associ (1339) 8684 885.0 0 NP_694568 (OMIM: 613324) spermatogenesis-associate ( 652) 4446 460.3 1.9e-128 NP_001273724 (OMIM: 613324) spermatogenesis-associ ( 574) 3793 394.9 8.5e-109 NP_001273723 (OMIM: 613324) spermatogenesis-associ ( 596) 3793 394.9 8.8e-109 NP_001273722 (OMIM: 613324) spermatogenesis-associ ( 512) 2644 279.7 3.4e-74 NP_056135 (OMIM: 605216) rho guanine nucleotide ex ( 690) 2352 250.6 2.7e-65 XP_005263738 (OMIM: 605216) PREDICTED: rho guanine (1876) 2352 250.9 6e-65 XP_005263744 (OMIM: 605216) PREDICTED: rho guanine ( 567) 2320 247.3 2.2e-64 NP_127462 (OMIM: 605216) rho guanine nucleotide ex ( 670) 2225 237.9 1.8e-61 XP_011509576 (OMIM: 605216) PREDICTED: rho guanine (1870) 2200 235.7 2.3e-60 XP_011529192 (OMIM: 300429,300607) PREDICTED: rho ( 516) 2165 231.8 9.5e-60 XP_016884854 (OMIM: 300429,300607) PREDICTED: rho ( 516) 2165 231.8 9.5e-60 XP_016884853 (OMIM: 300429,300607) PREDICTED: rho ( 521) 2165 231.8 9.6e-60 XP_016884852 (OMIM: 300429,300607) PREDICTED: rho ( 521) 2165 231.8 9.6e-60 XP_016884855 (OMIM: 300429,300607) PREDICTED: rho ( 516) 2163 231.6 1.1e-59 NP_056000 (OMIM: 300429,300607) rho guanine nucleo ( 516) 2163 231.6 1.1e-59 XP_005262306 (OMIM: 300429,300607) PREDICTED: rho ( 523) 2163 231.6 1.1e-59 NP_001317424 (OMIM: 300429,300607) rho guanine nuc ( 495) 2084 223.7 2.5e-57 XP_005262307 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57 XP_005262308 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57 XP_016884856 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57 XP_016884857 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57 XP_005263745 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57 XP_011509578 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57 XP_011509579 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57 XP_005263746 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57 NP_001166950 (OMIM: 300429,300607) rho guanine nuc ( 463) 1847 199.9 3.4e-50 XP_011529194 (OMIM: 300429,300607) PREDICTED: rho ( 456) 1844 199.6 4.1e-50 XP_016884862 (OMIM: 300429,300607) PREDICTED: rho ( 414) 1808 196.0 4.6e-49 NP_001166951 (OMIM: 300429,300607) rho guanine nuc ( 414) 1808 196.0 4.6e-49 XP_016884864 (OMIM: 300429,300607) PREDICTED: rho ( 385) 1611 176.2 3.8e-43 XP_016884865 (OMIM: 300429,300607) PREDICTED: rho ( 375) 1607 175.8 4.9e-43 XP_016884866 (OMIM: 300429,300607) PREDICTED: rho ( 365) 1599 175.0 8.4e-43 XP_016884867 (OMIM: 300429,300607) PREDICTED: rho ( 362) 1595 174.6 1.1e-42 XP_016884868 (OMIM: 300429,300607) PREDICTED: rho ( 344) 1520 167.1 1.9e-40 XP_016884859 (OMIM: 300429,300607) PREDICTED: rho ( 472) 1407 155.8 6.3e-37 XP_016884858 (OMIM: 300429,300607) PREDICTED: rho ( 479) 1407 155.8 6.4e-37 XP_016884860 (OMIM: 300429,300607) PREDICTED: rho ( 451) 1328 147.9 1.5e-34 XP_016884861 (OMIM: 300429,300607) PREDICTED: rho ( 451) 1328 147.9 1.5e-34 XP_016884869 (OMIM: 300429,300607) PREDICTED: rho ( 305) 1280 143.0 3e-33 XP_016884863 (OMIM: 300429,300607) PREDICTED: rho ( 412) 1088 123.8 2.4e-27 NP_079446 (OMIM: 612139) phosphatidylinositol 3,4, ( 979) 651 80.4 6.9e-14 XP_011515914 (OMIM: 612139) PREDICTED: phosphatidy (1157) 651 80.4 7.9e-14 NP_079146 (OMIM: 612139) phosphatidylinositol 3,4, (1606) 651 80.5 1e-13 NP_065871 (OMIM: 606905) phosphatidylinositol 3,4, (1659) 602 75.6 3.1e-12 XP_016859720 (OMIM: 605216) PREDICTED: rho guanine (1441) 541 69.5 1.9e-10 XP_006723397 (OMIM: 611893,616763) PREDICTED: plec (1327) 397 55.0 4e-06 XP_016882640 (OMIM: 611893,616763) PREDICTED: plec (1371) 397 55.0 4.1e-06 XP_016882639 (OMIM: 611893,616763) PREDICTED: plec (1374) 397 55.0 4.1e-06 >>NP_001159743 (OMIM: 613324) spermatogenesis-associated (1277 aa) initn: 8684 init1: 8684 opt: 8684 Z-score: 4716.7 bits: 885.0 E(85289): 0 Smith-Waterman score: 8684; 100.0% identity (100.0% similar) in 1277 aa overlap (1-1277:1-1277) 10 20 30 40 50 60 pF1KF0 MTQAAVRPWAPCLENMTTAPNGLGPGPAAPCAGSDLKDAKMVTSLACGNGVCGCSPGGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTQAAVRPWAPCLENMTTAPNGLGPGPAAPCAGSDLKDAKMVTSLACGNGVCGCSPGGDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 DTQEAKLSPAKLVRLFSTSRKRTGAHPERPHSMVLVGNSSTWNTLASFRKMGSFKKLKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTQEAKLSPAKLVRLFSTSRKRTGAHPERPHSMVLVGNSSTWNTLASFRKMGSFKKLKSS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 VLKGIQSREGSNACSKGEASEHGLGKSIPNGAVPGAQASRGSPLAPGPACGALRPAEWGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLKGIQSREGSNACSKGEASEHGLGKSIPNGAVPGAQASRGSPLAPGPACGALRPAEWGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 LDGSDLEDTDDAFQRSTHRSRSLRRAYGLGRICLLDAPQNHATPTIATGQVPAVCEILVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDGSDLEDTDDAFQRSTHRSRSLRRAYGLGRICLLDAPQNHATPTIATGQVPAVCEILVR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 DPENNSMGYRRSKSTDNLAFLKKSSFKRKSTSNLADLRTAHDARVPQRTLSSSSTDSQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPENNSMGYRRSKSTDNLAFLKKSSFKRKSTSNLADLRTAHDARVPQRTLSSSSTDSQKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 GSGRTKRWRSPIRAKDFDRVFKLVSNVTEAAWRRESPRSGAPSPGEASLRLQAHSRLHDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGRTKRWRSPIRAKDFDRVFKLVSNVTEAAWRRESPRSGAPSPGEASLRLQAHSRLHDD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 YSRRVSRSTEQDSRRGGAVMHGTTATCTVAPGFGSATSKGPHLDADTAVFPLETKSSWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSRRVSRSTEQDSRRGGAVMHGTTATCTVAPGFGSATSKGPHLDADTAVFPLETKSSWAV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 ESDSSCTCSSLPSPIVQDVLSKDSCDPNAGSQLTFDPEQPPTPLRPTTPKPQSPQSPQSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESDSSCTCSSLPSPIVQDVLSKDSCDPNAGSQLTFDPEQPPTPLRPTTPKPQSPQSPQSP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 GAGSASCHSNHSALSANSEESEGRAEEPAQREPGPVSLQDPLEATHGDEGSKDLLVNIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAGSASCHSNHSALSANSEESEGRAEEPAQREPGPVSLQDPLEATHGDEGSKDLLVNIGV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 AAGPEEKEKEEVVPDGPWRRSSSQDEERTEAQRTPKRRWGSGRRPRPRPFSDYGQLASRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGPEEKEKEEVVPDGPWRRSSSQDEERTEAQRTPKRRWGSGRRPRPRPFSDYGQLASRS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 LSIPEDSVAADPQKEDRVDEDPQASMTSASPEDQNAPVGCPKGARRRRPISVIGGVSLYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSIPEDSVAADPQKEDRVDEDPQASMTSASPEDQNAPVGCPKGARRRRPISVIGGVSLYG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KF0 TNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRAS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KF0 NVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVVCAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVVCAEAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KF0 WDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KF0 STPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KF0 MFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KF0 NNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KF0 YTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KF0 LIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KF0 RDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KF0 NQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKR 1210 1220 1230 1240 1250 1260 1270 pF1KF0 KSSLFWHTFNRLTPFRK ::::::::::::::::: NP_001 KSSLFWHTFNRLTPFRK 1270 >>NP_001273721 (OMIM: 613324) spermatogenesis-associated (1339 aa) initn: 8684 init1: 8684 opt: 8684 Z-score: 4716.4 bits: 885.0 E(85289): 0 Smith-Waterman score: 8684; 100.0% identity (100.0% similar) in 1277 aa overlap (1-1277:63-1339) 10 20 30 pF1KF0 MTQAAVRPWAPCLENMTTAPNGLGPGPAAP :::::::::::::::::::::::::::::: NP_001 DVQGRCECQDGIPGDEGLELRSADSAVPVAMTQAAVRPWAPCLENMTTAPNGLGPGPAAP 40 50 60 70 80 90 40 50 60 70 80 90 pF1KF0 CAGSDLKDAKMVTSLACGNGVCGCSPGGDTDTQEAKLSPAKLVRLFSTSRKRTGAHPERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CAGSDLKDAKMVTSLACGNGVCGCSPGGDTDTQEAKLSPAKLVRLFSTSRKRTGAHPERP 100 110 120 130 140 150 100 110 120 130 140 150 pF1KF0 HSMVLVGNSSTWNTLASFRKMGSFKKLKSSVLKGIQSREGSNACSKGEASEHGLGKSIPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSMVLVGNSSTWNTLASFRKMGSFKKLKSSVLKGIQSREGSNACSKGEASEHGLGKSIPN 160 170 180 190 200 210 160 170 180 190 200 210 pF1KF0 GAVPGAQASRGSPLAPGPACGALRPAEWGTLDGSDLEDTDDAFQRSTHRSRSLRRAYGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAVPGAQASRGSPLAPGPACGALRPAEWGTLDGSDLEDTDDAFQRSTHRSRSLRRAYGLG 220 230 240 250 260 270 220 230 240 250 260 270 pF1KF0 RICLLDAPQNHATPTIATGQVPAVCEILVRDPENNSMGYRRSKSTDNLAFLKKSSFKRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RICLLDAPQNHATPTIATGQVPAVCEILVRDPENNSMGYRRSKSTDNLAFLKKSSFKRKS 280 290 300 310 320 330 280 290 300 310 320 330 pF1KF0 TSNLADLRTAHDARVPQRTLSSSSTDSQKLGSGRTKRWRSPIRAKDFDRVFKLVSNVTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSNLADLRTAHDARVPQRTLSSSSTDSQKLGSGRTKRWRSPIRAKDFDRVFKLVSNVTEA 340 350 360 370 380 390 340 350 360 370 380 390 pF1KF0 AWRRESPRSGAPSPGEASLRLQAHSRLHDDYSRRVSRSTEQDSRRGGAVMHGTTATCTVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AWRRESPRSGAPSPGEASLRLQAHSRLHDDYSRRVSRSTEQDSRRGGAVMHGTTATCTVA 400 410 420 430 440 450 400 410 420 430 440 450 pF1KF0 PGFGSATSKGPHLDADTAVFPLETKSSWAVESDSSCTCSSLPSPIVQDVLSKDSCDPNAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGFGSATSKGPHLDADTAVFPLETKSSWAVESDSSCTCSSLPSPIVQDVLSKDSCDPNAG 460 470 480 490 500 510 460 470 480 490 500 510 pF1KF0 SQLTFDPEQPPTPLRPTTPKPQSPQSPQSPGAGSASCHSNHSALSANSEESEGRAEEPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQLTFDPEQPPTPLRPTTPKPQSPQSPQSPGAGSASCHSNHSALSANSEESEGRAEEPAQ 520 530 540 550 560 570 520 530 540 550 560 570 pF1KF0 REPGPVSLQDPLEATHGDEGSKDLLVNIGVAAGPEEKEKEEVVPDGPWRRSSSQDEERTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REPGPVSLQDPLEATHGDEGSKDLLVNIGVAAGPEEKEKEEVVPDGPWRRSSSQDEERTE 580 590 600 610 620 630 580 590 600 610 620 630 pF1KF0 AQRTPKRRWGSGRRPRPRPFSDYGQLASRSLSIPEDSVAADPQKEDRVDEDPQASMTSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQRTPKRRWGSGRRPRPRPFSDYGQLASRSLSIPEDSVAADPQKEDRVDEDPQASMTSAS 640 650 660 670 680 690 640 650 660 670 680 690 pF1KF0 PEDQNAPVGCPKGARRRRPISVIGGVSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDQNAPVGCPKGARRRRPISVIGGVSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKA 700 710 720 730 740 750 700 710 720 730 740 750 pF1KF0 VSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQ 760 770 780 790 800 810 760 770 780 790 800 810 pF1KF0 ASPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWW 820 830 840 850 860 870 820 830 840 850 860 870 pF1KF0 WGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVI 880 890 900 910 920 930 880 890 900 910 920 930 pF1KF0 REIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEK 940 950 960 970 980 990 940 950 960 970 980 990 pF1KF0 QYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQ 1000 1010 1020 1030 1040 1050 1000 1010 1020 1030 1040 1050 pF1KF0 QMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERK 1060 1070 1080 1090 1100 1110 1060 1070 1080 1090 1100 1110 pF1KF0 RKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVS 1120 1130 1140 1150 1160 1170 1120 1130 1140 1150 1160 1170 pF1KF0 CKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKK 1180 1190 1200 1210 1220 1230 1180 1190 1200 1210 1220 1230 pF1KF0 QEDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPH 1240 1250 1260 1270 1280 1290 1240 1250 1260 1270 pF1KF0 QGLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK 1300 1310 1320 1330 >>NP_694568 (OMIM: 613324) spermatogenesis-associated pr (652 aa) initn: 4446 init1: 4446 opt: 4446 Z-score: 2426.9 bits: 460.3 E(85289): 1.9e-128 Smith-Waterman score: 4446; 100.0% identity (100.0% similar) in 652 aa overlap (626-1277:1-652) 600 610 620 630 640 650 pF1KF0 LASRSLSIPEDSVAADPQKEDRVDEDPQASMTSASPEDQNAPVGCPKGARRRRPISVIGG :::::::::::::::::::::::::::::: NP_694 MTSASPEDQNAPVGCPKGARRRRPISVIGG 10 20 30 660 670 680 690 700 710 pF1KF0 VSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 VSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRR 40 50 60 70 80 90 720 730 740 750 760 770 pF1KF0 QMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 QMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVV 100 110 120 130 140 150 780 790 800 810 820 830 pF1KF0 CAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 CAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEEL 160 170 180 190 200 210 840 850 860 870 880 890 pF1KF0 SENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 SENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQC 220 230 240 250 260 270 900 910 920 930 940 950 pF1KF0 RKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 RKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAI 280 290 300 310 320 330 960 970 980 990 1000 1010 pF1KF0 YSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 YSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQL 340 350 360 370 380 390 1020 1030 1040 1050 1060 1070 pF1KF0 AELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 AELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDIL 400 410 420 430 440 450 1080 1090 1100 1110 1120 1130 pF1KF0 DRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 DRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELV 460 470 480 490 500 510 1140 1150 1160 1170 1180 1190 pF1KF0 DLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 DLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMG 520 530 540 550 560 570 1200 1210 1220 1230 1240 1250 pF1KF0 MEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_694 MEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGL 580 590 600 610 620 630 1260 1270 pF1KF0 AEPKRKSSLFWHTFNRLTPFRK :::::::::::::::::::::: NP_694 AEPKRKSSLFWHTFNRLTPFRK 640 650 >>NP_001273724 (OMIM: 613324) spermatogenesis-associated (574 aa) initn: 3793 init1: 3793 opt: 3793 Z-score: 2074.2 bits: 394.9 E(85289): 8.5e-109 Smith-Waterman score: 3793; 100.0% identity (100.0% similar) in 556 aa overlap (722-1277:19-574) 700 710 720 730 740 750 pF1KF0 SARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQA :::::::::::::::::::::::::::::: NP_001 MVARGEIARFWSLESLHLVSSDGGTEPSALVDDNGSEEDFSYEDLCQA 10 20 30 40 760 770 780 790 800 810 pF1KF0 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW 50 60 70 80 90 100 820 830 840 850 860 870 pF1KF0 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR 110 120 130 140 150 160 880 890 900 910 920 930 pF1KF0 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ 170 180 190 200 210 220 940 950 960 970 980 990 pF1KF0 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ 230 240 250 260 270 280 1000 1010 1020 1030 1040 1050 pF1KF0 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR 290 300 310 320 330 340 1060 1070 1080 1090 1100 1110 pF1KF0 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC 350 360 370 380 390 400 1120 1130 1140 1150 1160 1170 pF1KF0 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ 410 420 430 440 450 460 1180 1190 1200 1210 1220 1230 pF1KF0 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ 470 480 490 500 510 520 1240 1250 1260 1270 pF1KF0 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK :::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK 530 540 550 560 570 >>NP_001273723 (OMIM: 613324) spermatogenesis-associated (596 aa) initn: 3793 init1: 3793 opt: 3793 Z-score: 2074.0 bits: 394.9 E(85289): 8.8e-109 Smith-Waterman score: 3793; 100.0% identity (100.0% similar) in 556 aa overlap (722-1277:41-596) 700 710 720 730 740 750 pF1KF0 SARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQA :::::::::::::::::::::::::::::: NP_001 KKQRKKLDQGLILKKEKYRKEKKCASLSFEVSSDGGTEPSALVDDNGSEEDFSYEDLCQA 20 30 40 50 60 70 760 770 780 790 800 810 pF1KF0 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW 80 90 100 110 120 130 820 830 840 850 860 870 pF1KF0 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR 140 150 160 170 180 190 880 890 900 910 920 930 pF1KF0 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ 200 210 220 230 240 250 940 950 960 970 980 990 pF1KF0 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ 260 270 280 290 300 310 1000 1010 1020 1030 1040 1050 pF1KF0 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR 320 330 340 350 360 370 1060 1070 1080 1090 1100 1110 pF1KF0 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC 380 390 400 410 420 430 1120 1130 1140 1150 1160 1170 pF1KF0 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ 440 450 460 470 480 490 1180 1190 1200 1210 1220 1230 pF1KF0 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ 500 510 520 530 540 550 1240 1250 1260 1270 pF1KF0 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK :::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK 560 570 580 590 >>NP_001273722 (OMIM: 613324) spermatogenesis-associated (512 aa) initn: 2644 init1: 2644 opt: 2644 Z-score: 1453.0 bits: 279.7 E(85289): 3.4e-74 Smith-Waterman score: 3252; 88.8% identity (88.8% similar) in 556 aa overlap (722-1277:19-512) 700 710 720 730 740 750 pF1KF0 SARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQA :::::::::::::::::::::::::::::: NP_001 MVARGEIARFWSLESLHLVSSDGGTEPSALVDDNGSEEDFSYEDLCQA 10 20 30 40 760 770 780 790 800 810 pF1KF0 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW 50 60 70 80 90 100 820 830 840 850 860 870 pF1KF0 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR :::::::::::::::: NP_001 GRSEDKEAWFPASFVR-------------------------------------------- 110 120 880 890 900 910 920 930 pF1KF0 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ :::::::::::::::::::::::::::::::::::::::::: NP_001 ------------------GYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ 130 140 150 160 940 950 960 970 980 990 pF1KF0 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ 170 180 190 200 210 220 1000 1010 1020 1030 1040 1050 pF1KF0 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR 230 240 250 260 270 280 1060 1070 1080 1090 1100 1110 pF1KF0 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC 290 300 310 320 330 340 1120 1130 1140 1150 1160 1170 pF1KF0 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ 350 360 370 380 390 400 1180 1190 1200 1210 1220 1230 pF1KF0 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ 410 420 430 440 450 460 1240 1250 1260 1270 pF1KF0 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK :::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK 470 480 490 500 510 >>NP_056135 (OMIM: 605216) rho guanine nucleotide exchan (690 aa) initn: 2275 init1: 1140 opt: 2352 Z-score: 1293.1 bits: 250.6 E(85289): 2.7e-65 Smith-Waterman score: 2352; 60.3% identity (81.9% similar) in 587 aa overlap (696-1277:118-690) 670 680 690 700 710 720 pF1KF0 ELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSD : .:::.: ::...: .. .. . : NP_056 RLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTAMP-D 90 100 110 120 130 140 730 740 750 760 770 780 pF1KF0 GGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGG--EQLAINELISDGNVVCAEALWDH :. . .. .:. :::::. :.:: ..: .: .::: ::::::::::::.:::::::::: NP_056 GALDTAVCADEVGSEEDL-YDDLHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDH 150 160 170 180 190 200 790 800 810 820 830 840 pF1KF0 VTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTP ::::::::::::::::.:..:.:..::::: : :.:::::::::::::.: ..... NP_056 VTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLA 210 220 230 240 250 260 850 860 870 880 890 900 pF1KF0 SEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFT .. :... . .:.::::::: ::..::: ::::::::::::.:::::.. ::. NP_056 GNSGAEDGGAEAQS---SKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFS 270 280 290 300 310 320 910 920 930 940 950 960 pF1KF0 VAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNH :: ::::::::::. :. :.: ::...:.:.:::::.:.:::..: : ::::::::: NP_056 EEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNH 330 340 350 360 370 380 970 980 990 1000 1010 1020 pF1KF0 PGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTT :.::.::. : : .:: .:::::::::.::::..::::::::::::::::::::::::: NP_056 PNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTH 390 400 410 420 430 440 1030 1040 1050 1060 1070 1080 pF1KF0 QEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIH .: :.....:: .:::::: :::::::.::.:::::.:: :: ::: :.: ::::::. NP_056 PQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIY 450 460 470 480 490 500 1090 1100 1110 1120 1130 1140 pF1KF0 SGELTKITK-QGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRD :::::..:. :.::::: ::::::::. :::::::::.:::::::::: .:.::: ::.: NP_056 SGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKD 510 520 530 540 550 560 1150 1160 1170 1180 1190 1200 pF1KF0 KDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISENQ .: ..:.::::.: .: . .:.:..: :.: :::.: : ::..:: :.: :. :.: : NP_056 RDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQ 570 580 590 600 610 620 1210 1220 1230 1240 1250 1260 pF1KF0 KKLAMLNAQKAG-HGKSKGYNR-CPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKR .: :::::.: :: :. .: : .. .:.: ..:.. :::::. ::::.: NP_056 RKQAMLNASKQQVTGKPKAVGRPCYLT---------RQKHPALPSNRPQQQVLVLAEPRR 630 640 650 660 670 1270 pF1KF0 KSSLFWHTFNRLTPFRK : : :::...::.:::: NP_056 KPSTFWHSISRLAPFRK 680 690 >>XP_005263738 (OMIM: 605216) PREDICTED: rho guanine nuc (1876 aa) initn: 2338 init1: 1140 opt: 2352 Z-score: 1287.1 bits: 250.9 E(85289): 6e-65 Smith-Waterman score: 2458; 39.4% identity (62.8% similar) in 1254 aa overlap (77-1277:677-1876) 50 60 70 80 90 100 pF1KF0 CGNGVCGCSPGGDTDTQEAKLSPAKLVRLFSTSRKRT--GAHPERPHSMVLVGNSSTWNT : .: .: : . : : . . ..... . XP_005 NAGPVPETLPRDFPKERPESPLSTGETPCESPTRGKTPAGNECELPAAPIQGAGDGALQR 650 660 670 680 690 700 110 120 130 140 150 160 pF1KF0 LASFRKMGSFKKLKSSVLKGIQSREGSNACSKGEASEHGLGKSIPNGAVPG-AQASRGS- .:. ..: ... . ...: . .::. : :. :. : : : :.::. XP_005 VAQAAELGRVLVPQAASEETPSTEEPPGERLRGESRSSGSGERGPEEAPEGGAAAARGQR 710 720 730 740 750 760 170 180 190 200 210 220 pF1KF0 PLAPGPACGALRPAE--WGTLDGSDLEDTDDAFQRSTHRSRSLRRAYGLGRICLLDAPQN : .: ::.: . : :.. .:.. : :.:. :: ..: . XP_005 PRVP-----ALEPPQPPRGLRKGAQEPGKRPTFSKVT----SFRK----GRPLATESPGG 770 780 790 800 810 230 240 250 260 270 pF1KF0 HATPTIATGQVPAVC-EILVRDPENNSMGYRRSKSTDNLAFLKKSSFKRKSTSNLADLRT .:: . . : : :. . : ... : :.. . . .: :: XP_005 VPAPTTEGRRWGSSGPEGLPRENPPAAAG----RDAPPLHHGDASAWPEFVPQAAGD-RT 820 830 840 850 860 280 290 300 310 320 330 pF1KF0 AHDARVPQR----TLSSSSTDSQKLGSGRTKRWRSPIRAKDFDRVFKLVSNVTEA-AWRR : : . . :.: . .:.. .. : : .. .::. . . : :: :. . .. XP_005 AGPAGAGHTGTSGDLGSRGPSSESCNAKRLKTTEKKLRAR-LALAHKTFSNFIESIVLEK 870 880 890 900 910 920 340 350 360 370 380 390 pF1KF0 ESPRSGAPSPGEASLRLQAHSRLHDDYSRRVSRSTEQDSRRGGAVMHGTTATCTVAPGFG :. . .:: .. . .:::.. : .: . : . ... . ...:. XP_005 ENTHERSPSSPKGE---KEKSRLRQGSWRAFLKSKDAGSPKKPTLVSLPLGPEVLSPAET 930 940 950 960 970 980 400 410 420 430 440 450 pF1KF0 SATSKGPHLDADTAVFPLETKSSWAVESDSSCTCSSLPSPIVQDVLSKDSCDPNAGSQLT .. . : . :: .. :: :. ::: :: . . .:. : XP_005 DSHCEERAEDKEGYVF----SDHWAPPLASTPLSSSLVSP-----EHRRKSEPTIKCTAT 990 1000 1010 1020 1030 460 470 480 490 500 510 pF1KF0 FDPEQP-PTPLRPTTPKPQSPQSPQSPGAGSASCHSNHSA--LSANSEESEGRAEEPAQR . . :. . : :: ::.. :: : . :: :. .. . : : XP_005 QEGGRYLPSGIFPEKSWLASPGSPRAQQAGIAHTLPSSSACCLAYENPGTPCRPTSPKPL 1040 1050 1060 1070 1080 1090 520 530 540 550 560 pF1KF0 EPGPVSLQDPLEATHGDEGSKDLLVNIGV------AAGPEEKEKEEVVPDGPWR-----R : : . . :. . .:: .:..: ..: :. : .: : . XP_005 SPRPSAQRMGLH--YPGRGSAISMVSLGSYSYVDSSSGDPERPK---IPKGQTSFLLSLQ 1100 1110 1120 1130 1140 1150 570 580 590 600 610 pF1KF0 SSSQDEERTEAQRTPKRRWGSGRRP--RPRPFSD----YGQLASR--SLSIPEDSVAADP . .:::.. :... . : : : : : :. . . :.. : : . . .: XP_005 TLNQDEQKEESREGGQGPRGLGTVPWLRDLPGSENHMPWEEPAGEKPSCSHSQKAFHMEP 1160 1170 1180 1190 1200 1210 620 630 640 650 660 pF1KF0 QKEDRVDED--PQASMT-SASPEDQNAPVGCPKGARRRRPISVIGGVSLYGTNQTEELDN .. : : . :: .:: . :.: .: :.:: . : : : ..:.. XP_005 AQKPCFTTDMVTWALLCISAETVRGEAP-SQPRGIPHRSPVSV-DDLWLEKT-QRKKLQK 1220 1230 1240 1250 1260 670 680 690 700 710 pF1KF0 LLTQPASRPPMPA-HQ----------VPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMR .. : . : :. . .... : .:::.: ::...: .. XP_005 Q-AHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTP 1270 1280 1290 1300 1310 1320 720 730 740 750 760 770 pF1KF0 ASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGG--EQLAINELISDGNVVC .. . ::. . .. .:. :::::. :.:: ..: .: .::: ::::::::::::.::: XP_005 GTAMP-DGALDTAVCADEVGSEEDL-YDDLHSSSHHYSHPGGGGEQLAINELISDGSVVC 1330 1340 1350 1360 1370 1380 780 790 800 810 820 830 pF1KF0 AEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELS :::::::::::::::::::::::.:..:.:..::::: : :.:::::::::::::.: . XP_005 AEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPA 1390 1400 1410 1420 1430 1440 840 850 860 870 880 890 pF1KF0 ENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCR .... .. :... . .:.::::::: ::..::: ::::::::::::.:::: XP_005 DDDAPLAGNSGAEDGGAEAQS---SKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCR 1450 1460 1470 1480 1490 1500 900 910 920 930 940 950 pF1KF0 KHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIY :.. ::. :: ::::::::::. :. :.: ::...:.:.:::::.:.:::..: : :: XP_005 KRADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIY 1510 1520 1530 1540 1550 1560 960 970 980 990 1000 1010 pF1KF0 SEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLA ::::::::.::.::. : : .:: .:::::::::.::::..::::::::::::::::::: XP_005 SEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLA 1570 1580 1590 1600 1610 1620 1020 1030 1040 1050 1060 1070 pF1KF0 ELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILD :::::: .: :.....:: .:::::: :::::::.::.:::::.:: :: ::: :.: XP_005 ELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLV 1630 1640 1650 1660 1670 1680 1080 1090 1100 1110 1120 1130 pF1KF0 RSSELIHSGELTKITK-QGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELV ::::::.:::::..:. :.::::: ::::::::. :::::::::.:::::::::: .:.: XP_005 RSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVV 1690 1700 1710 1720 1730 1740 1140 1150 1160 1170 1180 1190 pF1KF0 DLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMG :: ::.:.: ..:.::::.: .: . .:.:..: :.: :::.: : ::..:: :.: : XP_005 DLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETG 1750 1760 1770 1780 1790 1800 1200 1210 1220 1230 1240 1250 pF1KF0 MEISENQKKLAMLNAQKAG-HGKSKGYNR-CPVAPPHQGLHPIHQRHITMPTSVPQQQVF . :.: :.: :::::.: :: :. .: : .. .:.: ..:.. :::::. XP_005 FSITELQRKQAMLNASKQQVTGKPKAVGRPCYLT---------RQKHPALPSNRPQQQVL 1810 1820 1830 1840 1850 1260 1270 pF1KF0 GLAEPKRKSSLFWHTFNRLTPFRK ::::.:: : :::...::.:::: XP_005 VLAEPRRKPSTFWHSISRLAPFRK 1860 1870 >>XP_005263744 (OMIM: 605216) PREDICTED: rho guanine nuc (567 aa) initn: 2309 init1: 1140 opt: 2320 Z-score: 1277.0 bits: 247.3 E(85289): 2.2e-64 Smith-Waterman score: 2320; 61.5% identity (82.6% similar) in 564 aa overlap (719-1277:17-567) 690 700 710 720 730 740 pF1KF0 KAVSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDL :. . ::. . .. .:. :::::. :.:: XP_005 MRGAVSRSWSLESLRSATAAMPDGALDTAVCADEVGSEEDL-YDDL 10 20 30 40 750 760 770 780 790 800 pF1KF0 CQASPRYLQPGG--EQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASN ..: .: .::: ::::::::::::.::::::::::::::::::::::::::.:..:.: XP_005 HSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATN 50 60 70 80 90 100 810 820 830 840 850 860 pF1KF0 KDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMR ..::::: : :.:::::::::::::.: ..... .. :... . .:.::: XP_005 REWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLAGNSGAEDGGAEAQS---SKDQMR 110 120 130 140 150 160 870 880 890 900 910 920 pF1KF0 TNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLK :::: ::..::: ::::::::::::.:::::.. ::. :: ::::::::::. :. :.: XP_005 TNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFSEEQLRTIFGNIEDIYRCQKAFVK 170 180 190 200 210 220 930 940 950 960 970 980 pF1KF0 DLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEAC ::...:.:.:::::.:.:::..: : ::::::::::.::.::. : : .:: .::::: XP_005 ALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEAC 230 240 250 260 270 280 990 1000 1010 1020 1030 1040 pF1KF0 RLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLI ::::.::::..::::::::::::::::::::::::: .: :.....:: .:::::: :: XP_005 RLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLI 290 300 310 320 330 340 1050 1060 1070 1080 1090 1100 pF1KF0 NERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITK-QGKSQQRTFFLFD :::::.::.:::::.:: :: ::: :.: ::::::.:::::..:. :.::::: ::::: XP_005 NERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFD 350 360 370 380 390 400 1110 1120 1130 1140 1150 1160 pF1KF0 HQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYL :::. :::::::::.:::::::::: .:.::: ::.:.: ..:.::::.: .: . .: XP_005 HQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHL 410 420 430 440 450 460 1170 1180 1190 1200 1210 1220 pF1KF0 FCAKKQEDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAG-HGKSKGYNR- .:..: :.: :::.: : ::..:: :.: :. :.: :.: :::::.: :: :. .: XP_005 LCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQRKQAMLNASKQQVTGKPKAVGRP 470 480 490 500 510 520 1230 1240 1250 1260 1270 pF1KF0 CPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK : .. .:.: ..:.. :::::. ::::.:: : :::...::.:::: XP_005 CYLT---------RQKHPALPSNRPQQQVLVLAEPRRKPSTFWHSISRLAPFRK 530 540 550 560 >>NP_127462 (OMIM: 605216) rho guanine nucleotide exchan (670 aa) initn: 1611 init1: 1140 opt: 2225 Z-score: 1224.6 bits: 237.9 E(85289): 1.8e-61 Smith-Waterman score: 2225; 60.5% identity (81.1% similar) in 562 aa overlap (696-1251:118-668) 670 680 690 700 710 720 pF1KF0 ELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSD : .:::.: ::...: .. .. . : NP_127 RLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTAMP-D 90 100 110 120 130 140 730 740 750 760 770 780 pF1KF0 GGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGG--EQLAINELISDGNVVCAEALWDH :. . .. .:. :::::. :.:: ..: .: .::: ::::::::::::.:::::::::: NP_127 GALDTAVCADEVGSEEDL-YDDLHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDH 150 160 170 180 190 200 790 800 810 820 830 840 pF1KF0 VTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTP ::::::::::::::::.:..:.:..::::: : :.:::::::::::::.: ..... NP_127 VTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLA 210 220 230 240 250 260 850 860 870 880 890 900 pF1KF0 SEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFT .. :... . .:.::::::: ::..::: ::::::::::::.:::::.. ::. NP_127 GNSGAEDGGAEAQ---SSKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFS 270 280 290 300 310 320 910 920 930 940 950 960 pF1KF0 VAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNH :: ::::::::::. :. :.: ::...:.:.:::::.:.:::..: : ::::::::: NP_127 EEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNH 330 340 350 360 370 380 970 980 990 1000 1010 1020 pF1KF0 PGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTT :.::.::. : : .:: .:::::::::.::::..::::::::::::::::::::::::: NP_127 PNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTH 390 400 410 420 430 440 1030 1040 1050 1060 1070 1080 pF1KF0 QEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIH .: :.....:: .:::::: :::::::.::.:::::.:: :: ::: :.: ::::::. NP_127 PQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIY 450 460 470 480 490 500 1090 1100 1110 1120 1130 1140 pF1KF0 SGELTKITK-QGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRD :::::..:. :.::::: ::::::::. :::::::::.:::::::::: .:.::: ::.: NP_127 SGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKD 510 520 530 540 550 560 1150 1160 1170 1180 1190 1200 pF1KF0 KDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISENQ .: ..:.::::.: .: . .:.:..: :.: :::.: : ::..:: :.: :. :.: : NP_127 RDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQ 570 580 590 600 610 620 1210 1220 1230 1240 1250 pF1KF0 KKLAMLNAQKAG-HGKSKGYNRCPVAPPHQ--GLHPIHQRHITMPTSVPQQQVFGLAEPK .: :::::.: :: :: : .::: . : .: .: : ::.: NP_127 RKQAMLNASKQQVTGKPKG--RRTAAPPPRLPGPYPAD----IIPFSEPQSQAS 630 640 650 660 670 1260 1270 pF1KF0 RKSSLFWHTFNRLTPFRK 1277 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:26:05 2016 done: Thu Nov 3 19:26:07 2016 Total Scan time: 13.100 Total Display time: 0.320 Function used was FASTA [36.3.4 Apr, 2011]