FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0267, 1101 aa 1>>>pF1KF0267 1101 - 1101 aa - 1101 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2872+/-0.000986; mu= 0.9957+/- 0.059 mean_var=297.8898+/-59.175, 0's: 0 Z-trim(114.9): 119 B-trim: 0 in 0/53 Lambda= 0.074310 statistics sampled from 15312 (15431) to 15312 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.474), width: 16 Scan time: 6.340 The best scores are: opt bits E(32554) CCDS30918.1 ARHGAP30 gene_id:257106|Hs108|chr1 (1101) 7429 810.7 0 CCDS72958.1 ARHGAP30 gene_id:257106|Hs108|chr1 ( 924) 6245 683.7 5e-196 CCDS1215.1 ARHGAP30 gene_id:257106|Hs108|chr1 ( 890) 4572 504.4 4.7e-142 CCDS54254.1 ARHGAP33 gene_id:115703|Hs108|chr19 (1123) 1076 129.6 3.8e-29 CCDS12477.1 ARHGAP33 gene_id:115703|Hs108|chr19 (1126) 1031 124.8 1.1e-27 CCDS31718.1 ARHGAP32 gene_id:9743|Hs108|chr11 (1738) 1027 124.5 2e-27 CCDS44769.1 ARHGAP32 gene_id:9743|Hs108|chr11 (2087) 1027 124.6 2.3e-27 CCDS43135.1 ARHGAP31 gene_id:57514|Hs108|chr3 (1444) 1000 121.6 1.3e-26 >>CCDS30918.1 ARHGAP30 gene_id:257106|Hs108|chr1 (1101 aa) initn: 7429 init1: 7429 opt: 7429 Z-score: 4317.8 bits: 810.7 E(32554): 0 Smith-Waterman score: 7429; 99.8% identity (99.9% similar) in 1101 aa overlap (1-1101:1-1101) 10 20 30 40 50 60 pF1KF0 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEV ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: CCDS30 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSLDSAGPRPEV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED 610 620 630 640 650 660 670 680 690 700 710 720 pF1KF0 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KF0 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KF0 EKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 EKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES 790 800 810 820 830 840 850 860 870 880 890 900 pF1KF0 GDGEAEGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 GDGEAEGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KF0 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KF0 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KF0 CTEGGDYCLIPRTPPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: CCDS30 CTEGGDYCLIPRTSPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL 1030 1040 1050 1060 1070 1080 1090 1100 pF1KF0 SSQRRSYAFETQANPGKGEGL ::::::::::::::::::::: CCDS30 SSQRRSYAFETQANPGKGEGL 1090 1100 >>CCDS72958.1 ARHGAP30 gene_id:257106|Hs108|chr1 (924 aa) initn: 6245 init1: 6245 opt: 6245 Z-score: 3632.8 bits: 683.7 E(32554): 5e-196 Smith-Waterman score: 6245; 99.6% identity (99.9% similar) in 924 aa overlap (178-1101:1-924) 150 160 170 180 190 200 pF1KF0 LMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFI ..:::::::::::::::::::::::::::: CCDS72 MKSKDIEASGFNGTAAFMEVRVQSIVVEFI 10 20 30 210 220 230 240 250 260 pF1KF0 LTHVDQLFGGAALSGGEVESGWRSLPGTRASGSPEDLMPRPLPYHLPSILQAGDGPPQMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LTHVDQLFGGAALSGGEVESGWRSLPGTRASGSPEDLMPRPLPYHLPSILQAGDGPPQMR 40 50 60 70 80 90 270 280 290 300 310 320 pF1KF0 PYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETKRKLPRGAEDREDKSNKGTLRPAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 PYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETKRKLPRGAEDREDKSNKGTLRPAKS 100 110 120 130 140 150 330 340 350 360 370 380 pF1KF0 MDSLSAAAGASDEPEGLVGPSSPRPSPLLPESLENDSIEAAEGEQEPEAEALGGTNSEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MDSLSAAAGASDEPEGLVGPSSPRPSPLLPESLENDSIEAAEGEQEPEAEALGGTNSEPG 160 170 180 190 200 210 390 400 410 420 430 440 pF1KF0 TPRAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLARLTRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 TPRAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLARLTRGL 220 230 240 250 260 270 450 460 470 480 490 500 pF1KF0 ECPALQHRPSPASGPGPGPGLGPGPPDEKLEASPASSPLADSGPDDLAPALEDSLSQEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 ECPALQHRPSPASGPGPGPGLGPGPPDEKLEASPASSPLADSGPDDLAPALEDSLSQEVQ 280 290 300 310 320 330 510 520 530 540 550 560 pF1KF0 DSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEEFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 DSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEEFS 340 350 360 370 380 390 570 580 590 600 610 620 pF1KF0 VEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEVEEENGEEVFLSAYDDLSPLLGPKPPIW :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS72 VEPPLDDLSLDEAQFVLAPSCCSLDSAGPRPEVEEENGEEVFLSAYDDLSPLLGPKPPIW 400 410 420 430 440 450 630 640 650 660 670 680 pF1KF0 KGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 KGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGK 460 470 480 490 500 510 690 700 710 720 730 740 pF1KF0 ASEDRGEAGGSQETKVRLREGSREETEAKEEKSKGQKKADSMEAKGVEEPGGDEYTDEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 ASEDRGEAGGSQETKVRLREGSREETEAKEEKSKGQKKADSMEAKGVEEPGGDEYTDEKE 520 530 540 550 560 570 750 760 770 780 790 800 pF1KF0 KEIEREEDEQREEAQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 KEIEREEDEQREEAQVEAGRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGY 580 590 600 610 620 630 810 820 830 840 850 860 pF1KF0 HEARKDQGDGEDSRSPEAATEGGAGEVSKERESGDGEAEGDQRAGGYYLEEDTLSEGSGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 HEARKDQGDGEDSRSPEAATEGGAGEVSKERESGDGEAEGDQRAGGYYLEEDTLSEGSGV 640 650 660 670 680 690 870 880 890 900 910 920 pF1KF0 ASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEPEGQPSPDGCLCPCSLGLGGVGMRLAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 ASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEPEGQPSPDGCLCPCSLGLGGVGMRLAST 700 710 720 730 740 750 930 940 950 960 970 980 pF1KF0 LVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVAPANPCPRPGRLDGTPGERAWGSRASRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVAPANPCPRPGRLDGTPGERAWGSRASRS 760 770 780 790 800 810 990 1000 1010 1020 1030 1040 pF1KF0 SWRNGGSLSFDAAVALARDRQRTEAQGVRRTQTCTEGGDYCLIPRTPPCSMISAHSPRPL :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: CCDS72 SWRNGGSLSFDAAVALARDRQRTEAQGVRRTQTCTEGGDYCLIPRTSPCSMISAHSPRPL 820 830 840 850 860 870 1050 1060 1070 1080 1090 1100 pF1KF0 SCLELPSEGAEGSGSRSRLSLPPREPQVPDPLLSSQRRSYAFETQANPGKGEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 SCLELPSEGAEGSGSRSRLSLPPREPQVPDPLLSSQRRSYAFETQANPGKGEGL 880 890 900 910 920 >>CCDS1215.1 ARHGAP30 gene_id:257106|Hs108|chr1 (890 aa) initn: 4681 init1: 4572 opt: 4572 Z-score: 2663.7 bits: 504.4 E(32554): 4.7e-142 Smith-Waterman score: 5624; 80.6% identity (80.7% similar) in 1101 aa overlap (1-1101:1-890) 10 20 30 40 50 60 pF1KF0 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 KDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAALSGGEVESGWRSLPGTRASGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PEDLMPRPLPYHLPSILQAGDGPPQMRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ETKRKLPRGAEDREDKSNKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ENDSIEAAEGEQEPEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PLHITSILSVPPNIISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEAS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEV ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: CCDS12 FSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSLDSAGPRPEV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EEENGEEVFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGED 610 620 630 640 650 660 670 680 690 700 710 720 pF1KF0 KQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKS :::::::::::::::::.: CCDS12 KQAEPGGRLDIREEAEGTP----------------------------------------- 670 730 740 750 760 770 780 pF1KF0 KGQKKADSMEAKGVEEPGGDEYTDEKEKEIEREEDEQREEAQVEAGRDLEQGAQEDQVAE CCDS12 ------------------------------------------------------------ 790 800 810 820 830 840 pF1KF0 EKWEVVQKQEAEGVREDEDKGQREKGYHEARKDQGDGEDSRSPEAATEGGAGEVSKERES CCDS12 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KF0 GDGEAEGDQRAGGYYLEEDTLSEGSGVASLEVDCAKEGNPHSSEMEEVAPQPPQPEEMEP :::::::::: CCDS12 --------------------------------------------------QPPQPEEMEP 680 910 920 930 940 950 960 pF1KF0 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EGQPSPDGCLCPCSLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVA 690 700 710 720 730 740 970 980 990 1000 1010 1020 pF1KF0 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSFDAAVALARDRQRTEAQGVRRTQT 750 760 770 780 790 800 1030 1040 1050 1060 1070 1080 pF1KF0 CTEGGDYCLIPRTPPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: CCDS12 CTEGGDYCLIPRTSPCSMISAHSPRPLSCLELPSEGAEGSGSRSRLSLPPREPQVPDPLL 810 820 830 840 850 860 1090 1100 pF1KF0 SSQRRSYAFETQANPGKGEGL ::::::::::::::::::::: CCDS12 SSQRRSYAFETQANPGKGEGL 870 880 890 >>CCDS54254.1 ARHGAP33 gene_id:115703|Hs108|chr19 (1123 aa) initn: 1114 init1: 996 opt: 1076 Z-score: 636.8 bits: 129.6 E(32554): 3.8e-29 Smith-Waterman score: 1123; 38.2% identity (57.8% similar) in 702 aa overlap (3-679:162-807) 10 20 30 pF1KF0 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQE :::. ...: ..::::::: :::..:::. CCDS54 PQGISSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQD 140 150 160 170 180 190 40 50 60 70 80 90 pF1KF0 VPQVLKSCAEFVEEYGVVDGIYRLSGVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSS :::::. :.::.: .:::::::::::::::::.::.::.::: :.: ..::::: ::: CCDS54 VPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSS 200 210 220 230 240 250 100 110 120 130 140 150 pF1KF0 LCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHL ::: ::::::.:::::.:: ::.::..: : ::::.. .:...:: :.:::::.:.::: CCDS54 LCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHL 260 270 280 290 300 310 160 170 180 190 200 210 pF1KF0 VHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVD ..:: ::.:.::::::::::::::::: ..:. :..:.::: ::::::.::::.::::: CCDS54 ARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVD 320 330 340 350 360 370 220 230 240 250 260 270 pF1KF0 QLFGGAALSGGEVESGWRSLPGTRA-SGSPEDLMPRPLPYHLPSILQAGD-GPPQMRPYH ::. . :.: .: :: .. .:: . : : . . : : : CCDS54 VLFSDTFTSAGLDPAGRCLLPRPKSLAGSCPST--RLLTLEEAQARTQGRLGTPTEPTTP 380 390 400 410 420 280 290 300 310 320 pF1KF0 TIIEIAEHKRKG--SLKVRK-----WRSIFNLGRSGHETKRK-LPRGAEDREDKSNKG-- ..::: . : :: :...: :::. ..: :: . : . .: CCDS54 KAPASPAERRKGERGEKQRKPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGSR 430 440 450 460 470 480 330 340 350 360 370 pF1KF0 ----TLRPAKSMDSLSA-AAGAS-DEPEGLVGP-SSPRPSPLLPESLENDSIEAAEGEQE ::: ::: .:::. :.::. .. . : : :: :. : : :. . . CCDS54 PDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGPA--PAGSCESLSSSSS 490 500 510 520 530 540 380 390 400 410 420 430 pF1KF0 PEAEALGGTNSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPN :. . ...: . :: .:. .:: . : . .: . . :: CCDS54 SESSSSESSSSSSESSAAGLGAL--SGSPSHRTSAWLDDGDELDFS-----------PPR 550 560 570 580 590 440 450 460 470 480 490 pF1KF0 IISNVSLARLTRGLECPALQHRPSPASGPGPGPGLGPGPPDEKLEASPASSPLADSGPDD . .. :::. : : : . :.: .:.:: : .: : : CCDS54 CLEGL------RGLDFDPLTFRCSSPTPGDPAPPASPAPPAPASAFPPRVTPQAISPRGP 600 610 620 630 640 500 510 520 530 540 pF1KF0 LAPALEDSLSQEVQDSFSFLEDSSSSEP---EWVGAEDGEVAQAEAAGAAFSPGED-DPG .:: .: .... .. : : : .:: : :.: . :.:::.. : CCDS54 TSPASPAAL--DISEPLAV-----SVPPAVLELLGA-GGAPASATPT-PALSPGRSLRP- 650 660 670 680 690 550 560 570 580 590 600 pF1KF0 MGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSA-GPR-PEVEEENGEE .: :: : .: :: : .: : .. .: :: :..: CCDS54 --HLIPLLLRG-------AEAPLTDACQQEM-------CSKLRGAQGPLGPDMESPLPPP 700 710 720 730 740 610 620 630 640 650 660 pF1KF0 VFLSAYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGG :: : : .: :: :. . : . : . : ... .: : . .:. : CCDS54 P-LSL---LRPGGAPPPPP-KNPARLMALALAERAQQVAEQQSQQECGGTPPASQS-PFH 750 760 770 780 790 670 680 690 700 710 720 pF1KF0 RLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREGSREETEAKEEKSKGQKKAD : .. :. : : CCDS54 R-SLSLEVGGEPLGTSGSGPPPNSLAHPGAWVPGPPPYLPRQQSDGSLLRSQRPMGTSRR 800 810 820 830 840 850 >>CCDS12477.1 ARHGAP33 gene_id:115703|Hs108|chr19 (1126 aa) initn: 1116 init1: 996 opt: 1031 Z-score: 610.7 bits: 124.8 E(32554): 1.1e-27 Smith-Waterman score: 1098; 37.3% identity (57.9% similar) in 689 aa overlap (3-647:298-963) 10 20 30 pF1KF0 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQE :::. ...: ..::::::: :::..:::. CCDS12 PQGISSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQD 270 280 290 300 310 320 40 50 60 70 80 90 pF1KF0 VPQVLKSCAEFVEEYGVVDGIYRLSGVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSS :::::. :.::.: .:::::::::::::::::.::.::.::: :.: ..::::: ::: CCDS12 VPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSS 330 340 350 360 370 380 100 110 120 130 140 150 pF1KF0 LCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHL ::: ::::::.:::::.:: ::.::..: : ::::.. .:...:: :.:::::.:.::: CCDS12 LCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHL 390 400 410 420 430 440 160 170 180 190 200 210 pF1KF0 VHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVD ..:: ::.:.::::::::::::::::: ..:. :..:.::: ::::::.::::.::::: CCDS12 ARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVD 450 460 470 480 490 500 220 230 240 250 260 pF1KF0 QLFGGAALSGGEVESGWRSLPGTRA-SGS-PEDLMPRPLPYHLPSILQAGD-GPPQMRPY ::. . :.: .: :: .. .:: : : : . . : : : CCDS12 VLFSDTFTSAGLDPAGRCLLPRPKSLAGSCPST---RLLTLEEAQARTQGRLGTPTEPTT 510 520 530 540 550 560 270 280 290 300 310 320 pF1KF0 HTIIEIAEHKRKG--SLKVRK-----WRSIFNLGRSGHETKRK-LPRGAEDREDKSNKG- ..::: . : :: :...: :::. ..: :: . : . .: CCDS12 PKAPASPAERRKGERGEKQRKPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGS 570 580 590 600 610 620 330 340 350 360 pF1KF0 -----TLRPAKSMDSLSAAAG-----------ASDEPEGLVGPS-SPRPS--PLLPESLE ::: ::: .:::. :. :: : ..:. : :: ::: .. : CCDS12 RPDTVTLRSAKSEESLSSQASGAELLGAGGAPASATPTPALSPGRSLRPHLIPLLLRGAE 630 640 650 660 670 680 370 380 390 400 410 pF1KF0 NDSIEAAEGEQEPEAE-ALG--GTNSEPGTPRAGRSAIRAGGS-----SRAERCAGVHIS .: . :. . . : : : . : : : .: ::. . : .. .. CCDS12 APLTDACQQEMCSKLRGAQGPLGPDMESPLPPPPLSLLRPGGAPPPPPKNPARLMALALA 690 700 710 720 730 740 420 430 440 450 460 470 pF1KF0 D-PYNVNLPLHITSILSVPPNIIS--NVSLARLTRGLECPALQHRPSPASGPGPGPGLGP . .: ..:: : . ::. . : . : : : :: . : CCDS12 ERAQQVAEQQSQQECGGTPPASQSPFHRSLSLEVGGEPLGTSGSGPPPNSLAHPGAWV-P 750 760 770 780 790 800 480 490 500 510 520 pF1KF0 GPPDEKLEASPASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSE-PEWVGAEDG ::: . . .: : .. : . . .: .: : .. ... . :: .. CCDS12 GPPPYLPRQQSDGSLLRSQRPMGTS---RRGLRGPAQVSAQLRAGGGGRDAPEAAAQSPC 810 820 830 840 850 860 530 540 550 560 570 580 pF1KF0 EVAQAEAAGAAFSPGEDDPGMGYLEELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCC : . . . :::. . : .::: :. . . :: :.. . .:. CCDS12 SVPSQVPTPGFFSPAPRE----CLPPFLGV-PKPGLYPLGPP----SFQPS----SPAPV 870 880 890 900 590 600 610 620 630 640 pF1KF0 SVDSAGPRPEVEEENGEEVFLS-AYDDLSPLLGPKPPIWKGSGSLEGEAAGCGRQALGQG .: :: ... ::... . .. :: :: :. :. . . . ::: CCDS12 WRSSLGPPAPLDR--GENLYYEIGASEGSPYSGPTRS-WSPFRSMPPDRLNASYGMLGQS 910 920 930 940 950 960 650 660 670 680 690 700 pF1KF0 GEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLREG CCDS12 PPLHRSPDFLLSYPPAPSCFPPDHLGYSAPQHPARRPTPPEPLYVNLALGPRGPSPASSS 970 980 990 1000 1010 1020 >>CCDS31718.1 ARHGAP32 gene_id:9743|Hs108|chr11 (1738 aa) initn: 1248 init1: 1001 opt: 1027 Z-score: 605.8 bits: 124.5 E(32554): 2e-27 Smith-Waterman score: 1198; 39.5% identity (62.0% similar) in 663 aa overlap (1-619:1-628) 10 20 30 40 50 pF1KF0 MKSR---QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLS :::: :: :..: ::::::::: ::: .:: ::::::.::. :.:.::.:::::::: CCDS31 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KF0 GVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEA ::.::::.::.::.::. ::: .. :.:::: :.:::: ::::::.:::::.::.::..: CCDS31 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KF0 VGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL :.. . :::.:: .:...:: :.::::::::::: .:.. . :::::.:::::::::: CCDS31 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KF0 LRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGG----AALSGGEVESGWRSL- ::::.::.. :.:::::::::.::.::::::.::: ::.: : :. : .:: CCDS31 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL 190 200 210 220 230 240 240 250 260 270 280 pF1KF0 ---PGTRASGSPEDLMPRPLPYHLPSI-----LQAGDGPPQMR-PYHTIIEIAEHKRKGS :.:. : . : . ...:.:: .. .:::::. .... . CCDS31 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ 250 260 270 280 290 300 290 300 310 320 330 pF1KF0 LKVRK-----WRSIFNLGRSGHETKRKLPRG-AEDREDKS-------NKGTLRPAKSMDS :..: :::.::::.:. .:::: :. .: : :. .:::: ::: .: CCDS31 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES 310 320 330 340 350 360 340 350 360 370 380 pF1KF0 LSAAAGASDEPEGLVGPSSPRPSPLLPESLENDSIEAAEGEQEPEAEALGGT-NSEPGTP :.. : : : : :: : .:.. :. . .: ::. :: . : CCDS31 LTSLH-AVDGDSKLFRPRRPRSS--------SDALSASFN-----GEMLGNRCNSYDNLP 370 380 390 400 390 400 410 420 430 440 pF1KF0 RAGRSAIRAGGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLARLTRGLEC . ..: . :: .:: : .. : .. ::.: . .:: ...: CCDS31 HDNESE-EEGGL--------LHI--PALMS-PHSAEDVDLSPPDI-GVASLDFDPMSFQC 410 420 430 440 450 450 460 470 480 490 500 pF1KF0 -PALQHRPSPASGPG--PGPGLGPGPP-----DEKLEASPASSPLADSGPDDLAPALEDS : . :: . .:: . : : . .: ..: . .. . ..: :... CCDS31 SPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSP-LQEK 460 470 480 490 500 510 510 520 530 540 550 560 pF1KF0 LSQEVQDSFSFLEDSSSSEPEWVGAEDGEVAQAEAAGAAFSPGEDDPGMGYLEEL-LGVG :: ..: ::.::. .. : : . : .: .:.:. : . . . CCDS31 LSPFFTLDLSPTEDKSSKPSSFT--EKVVYAFSPKIGRKLS---KSPSMSISEPISVTLP 520 530 540 550 560 570 580 590 600 610 pF1KF0 PQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSA---GPRPEVEEENGEEVFLSAYD-DL :.: : : ... . ..:. .: .: .: :. ...: : ::. .. CCDS31 PRVSE--VIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEV 570 580 590 600 610 620 620 630 640 650 660 670 pF1KF0 SPLLGPKPPIWKGSGSLEGEAAGCGRQALGQGGEEQACWEVGEDKQAEPGGRLDIREEAE .:: CCDS31 QPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPP 630 640 650 660 670 680 >>CCDS44769.1 ARHGAP32 gene_id:9743|Hs108|chr11 (2087 aa) initn: 1248 init1: 1001 opt: 1027 Z-score: 604.7 bits: 124.6 E(32554): 2.3e-27 Smith-Waterman score: 1198; 39.5% identity (62.0% similar) in 663 aa overlap (1-619:350-977) 10 20 pF1KF0 MKSR---QKGKKKGSAKERVFGCDLQEHLQ :::: :: :..: ::::::::: ::: CCDS44 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL 320 330 340 350 360 370 30 40 50 60 70 80 pF1KF0 HSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVSSNIQKLRQEFESERKPDLRRDVYLQDI .:: ::::::.::. :.:.::.::::::::::.::::.::.::.::. ::: .. :.::: CCDS44 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI 380 390 400 410 420 430 90 100 110 120 130 140 pF1KF0 HCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEF : :.:::: ::::::.:::::.::.::..::.. . :::.:: .:...:: :.:::::: CCDS44 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF 440 450 460 470 480 490 150 160 170 180 190 200 pF1KF0 LMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFI ::::: .:.. . :::::.::::::::::::::.::.. :.:::::::::.::.::::: CCDS44 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI 500 510 520 530 540 550 210 220 230 240 250 pF1KF0 LTHVDQLFGG----AALSGGEVESGWRSL----PGTRASGSPEDLMPRPLPYHLPSI--- :.::: ::.: : :. : .:: :.:. : . : . CCDS44 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN 560 570 580 590 600 610 260 270 280 290 300 pF1KF0 --LQAGDGPPQMR-PYHTIIEIAEHKRKGSLKVRK-----WRSIFNLGRSGHETKRKLPR ...:.:: .. .:::::. .... . :..: :::.::::.:. .:::: : CCDS44 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR 620 630 640 650 660 670 310 320 330 340 350 360 pF1KF0 G-AEDREDKS-------NKGTLRPAKSMDSLSAAAGASDEPEGLVGPSSPRPSPLLPESL . .: : :. .:::: ::: .::.. : : : : :: : CCDS44 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLH-AVDGDSKLFRPRRPRSS------- 680 690 700 710 720 730 370 380 390 400 410 pF1KF0 ENDSIEAAEGEQEPEAEALGGT-NSEPGTPRAGRSAIRAGGSSRAERCAGVHISDPYNVN .:.. :. . .: ::. :: . :. ..: . :: .:: : .. CCDS44 -SDALSASFN-----GEMLGNRCNSYDNLPHDNESE-EEGGL--------LHI--PALMS 740 750 760 770 420 430 440 450 460 470 pF1KF0 LPLHITSILSVPPNIISNVSLARLTRGLEC-PALQHRPSPASGPG--PGPGLGPGPP--- : .. ::.: . .:: ...: : . :: . .:: . : CCDS44 -PHSAEDVDLSPPDI-GVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKPSAN 780 790 800 810 820 830 480 490 500 510 520 530 pF1KF0 --DEKLEASPASSPLADSGPDDLAPALEDSLSQEVQDSFSFLEDSSSSEPEWVGAEDGEV : . .: ..: . .. . ..: :...:: ..: ::.::. .. : CCDS44 KKDAETGSSQCQTPGSTASSEPVSP-LQEKLSPFFTLDLSPTEDKSSKPSSFT--EKVVY 840 850 860 870 880 540 550 560 570 580 590 pF1KF0 AQAEAAGAAFSPGEDDPGMGYLEEL-LGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCS : . : .: .:.:. : . . . :.: : : ... . ..:. .: CCDS44 AFSPKIGRKLS---KSPSMSISEPISVTLPPRVSE--VIGTVSNTTAQNASSSTWDKCVE 890 900 910 920 930 940 600 610 620 630 640 pF1KF0 VDSA---GPRPEVEEENGEEVFLSAYD-DLSPLLGPKPPIWKGSGSLEGEAAGCGRQALG .: .: :. ...: : ::. ...:: CCDS44 ERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVA 950 960 970 980 990 1000 650 660 670 680 690 700 pF1KF0 QGGEEQACWEVGEDKQAEPGGRLDIREEAEGSPETKVEAGKASEDRGEAGGSQETKVRLR CCDS44 SGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGT 1010 1020 1030 1040 1050 1060 >>CCDS43135.1 ARHGAP31 gene_id:57514|Hs108|chr3 (1444 aa) initn: 1262 init1: 970 opt: 1000 Z-score: 591.3 bits: 121.6 E(32554): 1.3e-26 Smith-Waterman score: 1223; 30.2% identity (55.9% similar) in 1142 aa overlap (3-1004:6-1116) 10 20 30 40 50 pF1KF0 MKSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLS ..:: :.::.:. .::::: :.:. :::.:: ::::::::.: .:.:::::::: CCDS43 MKNKGAKQKLKRKGAAS--AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLS 10 20 30 40 50 60 70 80 90 100 110 pF1KF0 GVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEA ::.::::.::::: :.. ::: :.:::::::::.:::: ::::::.:::::.::.::.:: CCDS43 GVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KF0 VGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL :. : .:..: .:..::: .:::::.:.:::.:.::::..:::::::::.:::::: CCDS43 VSHCPEEGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KF0 LRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGAA---LSGGEVESGWRSL-- ::::.:::.: :: :::. ::::..:.::::.::::.:...: : . : . .:: CCDS43 LRSKEIEATGCNGDAAFLAVRVQQVVIEFILNHVDQIFNNGAPGSLENDENRPIMKSLTL 180 190 200 210 220 230 240 250 260 270 280 pF1KF0 PGTRASG---SPEDLMPRPLPYHLPSILQAGDG------PPQMRPYHTIIEIAEHKRKGS :. : :. . : : . :. . .. ::. .::..:. ..::: : CCDS43 PALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEIVPPMGTLFHTVLELPDNKRKLS 240 250 260 270 280 290 290 300 310 320 330 pF1KF0 LKVRKWRSIFNLGRSGHETKRKLPRGA----EDREDKSNKGTLRPAKSMDSLSAAAGASD : .::.::::::::: ..: :: :.. . .. . .:.:.::::::::: .. . CCDS43 SKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGK 300 310 320 330 340 350 340 350 360 370 pF1KF0 EPEGLVGPSSPRPSPLLPESLENDS-------IEAAEGE--QE---PEAEA--------- : .: . . . ..: . ... . ::: :: : ::. CCDS43 ETKGNFNRTVTTGGFFIPATKMHSTGTGSSCDLTKQEGEWGQEGMPPGAEGGFDVSSDRS 360 370 380 390 400 410 380 390 400 pF1KF0 -LGGTNSEPGT-----------PRAGRSAIRAGG-----------------------SSR : :....: :.. ..: . : : : CCDS43 HLQGAQARPPPEQLKVFRPVEDPESEQTAPKMLGMFYTSNDSPSKSVFTSSLFQMEPSPR 420 430 440 450 460 470 410 420 430 440 450 pF1KF0 AERCAGVHISDPYNVNLPLHITSILSV-------PPNIISNVS-LARLT-RGLECPALQH .: : ..::.:. :..::......:. ::. ....: : ... .: : . . CCDS43 NQRKA-LNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQSLSSLEEFSFHGSESGGWPE 480 490 500 510 520 530 460 470 480 490 500 510 pF1KF0 RPSPASGPGPGPGLGP--GPPDEK-LEASPASSPLADSGPDDLAPALEDSLSQEVQDSFS . .: .. . .. : : : . .:.. . . .. . ::.. . : . : . CCDS43 EEKPLGAETSAASVPKKAGLEDAKAVPEAPGTVECSKGLSQEPGAHLEEKKTPESSLSSQ 540 550 560 570 580 590 520 530 540 550 pF1KF0 FLED-SSSSEPEWVGAEDGEVAQAEAAGAAFSP------------GEDDPGMGYL----E :.. . .:: : : :... :.. :: ::: . . . . CCDS43 HLNELEKRPNPEKVVEEGREAGEMESSTLQESPRARAEAVLLHEMDEDDLANALIWPEIQ 600 610 620 630 640 650 560 570 580 590 600 610 pF1KF0 ELLGVGPQVEEFSVEPPLDDLSLDEAQFVLAPSCCSVDSAGPRPEVEEENGEEVFLSAYD . : . . ::.: :: :. . : .: .: :: : .. : . CCDS43 QELKIIESEEELSSLPP-PALKTSPIQPILE------SSLGPFIPSEPPGS----LPCGS 660 670 680 690 700 620 630 640 650 660 pF1KF0 DLSPLLGPKPPIWK---GSGSLEGEAAGCGR------QALGQGGEEQACWEVGEDKQAEP .:. : .: .. : .: ... .: :.: : :. ..: : CCDS43 FPAPVSTPLE-VWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKASP 710 720 730 740 750 760 670 680 690 700 710 pF1KF0 GGRLDIREEAEGSPE--------------TKVEAGKASEDRGEAGGSQETKVRLREGSRE . ... .. :: : : .:.. .: ... . .: . . . . . CCDS43 QATVEVGGPGNLSPPLPPAPPPPTPLEESTPVLLSKGGPEREDSSRKLRTDLYIDQLKSQ 770 780 790 800 810 820 720 730 740 750 760 pF1KF0 ETEAKEEKSKGQ----KKADSMEAKGVEEPG-GDEY-TDEKEKEIEREEDEQREEAQVEA .. .:. ...:....:.. : : . . .: :: .:.:. .. :. CCDS43 DSPEISSLCQGEEATPRHSDKQNSKNAASEGKGCGFPSPTREVEIVSQEEEDVTHS-VQE 830 840 850 860 870 880 770 780 790 800 810 820 pF1KF0 GRDLEQGAQEDQVAEEKWEVVQKQEAEGVREDEDKGQREKGYHEARKD--QGDGEDSR-S : .. ..:.. :.:. : . .. : :.:. . :: ..: : CCDS43 PSDCDEDDTVTDIAQHGLEMVEPWEEPQWVTSPLHSPTLKDAHKAQVQGLQGHQLEKRLS 890 900 910 920 930 940 830 840 850 860 870 880 pF1KF0 PEAATEGGAGEVSKERESGDGEAEGDQRAGGYYLEEDTLSEG--SGVASLEVDCAKEGNP . . . . . :: ... : . .. :: . :. . :. : CCDS43 HRPSLRQSHSLDSKPTVKSQWTLEVPSSSSCANLETERNSDPLQPQAPRREITGWDEKAL 950 960 970 980 990 1000 890 900 910 920 930 pF1KF0 HS-SEMEEVAPQPPQPEEMEPEG-QPSPDGCLCPCSLGLGG-VGMRLASTLVQVQQVRSV .: :. . :.. : : ::.: . : ::. : .: .:. . :..: .: CCDS43 RSFREFSGLKGAEAPPNQKGPSGVQPNP-AETSPISLAEGKELGTHLGHSSPQIRQ-GGV 1010 1020 1030 1040 1050 1060 940 950 960 970 980 990 pF1KF0 PVVPPKPQFAKMPSAMCSKIHVAPANPCPRPGRLDGTPGERAWGSRASRSSWRNGGSLSF : :. . . ::.. : ..: .:..:. : . . .: : ::.. CCDS43 P--GPESSKESSPSVQDS------TSPGEHPAKLQLKSTECGPPKGKNRPS-----SLNL 1070 1080 1090 1100 1000 1010 1020 1030 1040 1050 pF1KF0 DAAVALARDRQRTEAQGVRRTQTCTEGGDYCLIPRTPPCSMISAHSPRPLSCLELPSEGA : :. .: CCDS43 DPAIPIADLFWFENVASFSSPGMQVSEPGDPKVTWMTSSYCKADPWRVYSQDPQDLDIVA 1110 1120 1130 1140 1150 1160 1101 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:08:52 2016 done: Fri Nov 4 20:08:53 2016 Total Scan time: 6.340 Total Display time: 0.340 Function used was FASTA [36.3.4 Apr, 2011]