FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0405, 402 aa 1>>>pF1KF0405 402 - 402 aa - 402 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0780+/-0.00037; mu= 18.0219+/- 0.023 mean_var=63.2233+/-13.059, 0's: 0 Z-trim(111.9): 32 B-trim: 0 in 0/51 Lambda= 0.161300 statistics sampled from 20648 (20679) to 20648 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.242), width: 16 Scan time: 8.340 The best scores are: opt bits E(85289) NP_663624 (OMIM: 110800,116700,600429) N-acetyllac ( 402) 2751 649.1 5.6e-186 XP_006715115 (OMIM: 110800,116700,600429) PREDICTE ( 402) 2751 649.1 5.6e-186 XP_005249056 (OMIM: 110800,116700,600429) PREDICTE ( 325) 2239 529.9 3.5e-150 XP_016866221 (OMIM: 110800,116700,600429) PREDICTE ( 318) 2077 492.2 7.6e-139 XP_011512770 (OMIM: 110800,116700,600429) PREDICTE ( 318) 2077 492.2 7.6e-139 NP_663630 (OMIM: 110800,116700,600429) N-acetyllac ( 402) 2047 485.3 1.2e-136 NP_001482 (OMIM: 110800,116700,600429) N-acetyllac ( 400) 2014 477.6 2.4e-134 XP_011512768 (OMIM: 110800,116700,600429) PREDICTE ( 339) 1387 331.6 1.7e-90 XP_005249054 (OMIM: 110800,116700,600429) PREDICTE ( 363) 1332 318.8 1.3e-86 NP_004742 (OMIM: 606836) beta-1,3-galactosyl-O-gly ( 438) 984 237.9 3.6e-62 NP_057675 (OMIM: 616782) beta-1,3-galactosyl-O-gly ( 453) 969 234.4 4.2e-61 NP_001091102 (OMIM: 600391) beta-1,3-galactosyl-O- ( 428) 921 223.2 9.2e-58 NP_001091103 (OMIM: 600391) beta-1,3-galactosyl-O- ( 428) 921 223.2 9.2e-58 NP_001481 (OMIM: 600391) beta-1,3-galactosyl-O-gly ( 428) 921 223.2 9.2e-58 XP_016870109 (OMIM: 600391) PREDICTED: beta-1,3-ga ( 428) 921 223.2 9.2e-58 XP_016870110 (OMIM: 600391) PREDICTED: beta-1,3-ga ( 428) 921 223.2 9.2e-58 NP_001091105 (OMIM: 600391) beta-1,3-galactosyl-O- ( 428) 921 223.2 9.2e-58 NP_001091104 (OMIM: 600391) beta-1,3-galactosyl-O- ( 428) 921 223.2 9.2e-58 XP_005257629 (OMIM: 264800,605822,608125) PREDICTE ( 833) 307 80.5 1.6e-14 NP_071450 (OMIM: 264800,605822,608125) xylosyltran ( 865) 307 80.5 1.7e-14 XP_016879029 (OMIM: 264800,608124,615777) PREDICTE ( 870) 264 70.5 1.7e-11 XP_016879028 (OMIM: 264800,608124,615777) PREDICTE ( 872) 264 70.5 1.7e-11 NP_071449 (OMIM: 264800,608124,615777) xylosyltran ( 959) 264 70.6 1.9e-11 >>NP_663624 (OMIM: 110800,116700,600429) N-acetyllactosa (402 aa) initn: 2751 init1: 2751 opt: 2751 Z-score: 3459.9 bits: 649.1 E(85289): 5.6e-186 Smith-Waterman score: 2751; 100.0% identity (100.0% similar) in 402 aa overlap (1-402:1-402) 10 20 30 40 50 60 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS 310 320 330 340 350 360 370 380 390 400 pF1KF0 PSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF :::::::::::::::::::::::::::::::::::::::::: NP_663 PSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF 370 380 390 400 >>XP_006715115 (OMIM: 110800,116700,600429) PREDICTED: N (402 aa) initn: 2751 init1: 2751 opt: 2751 Z-score: 3459.9 bits: 649.1 E(85289): 5.6e-186 Smith-Waterman score: 2751; 100.0% identity (100.0% similar) in 402 aa overlap (1-402:1-402) 10 20 30 40 50 60 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS 310 320 330 340 350 360 370 380 390 400 pF1KF0 PSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF :::::::::::::::::::::::::::::::::::::::::: XP_006 PSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF 370 380 390 400 >>XP_005249056 (OMIM: 110800,116700,600429) PREDICTED: N (325 aa) initn: 2239 init1: 2239 opt: 2239 Z-score: 2817.3 bits: 529.9 E(85289): 3.5e-150 Smith-Waterman score: 2239; 100.0% identity (100.0% similar) in 325 aa overlap (78-402:1-325) 50 60 70 80 90 100 pF1KF0 ACHQIFEGKVFYPTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDF :::::::::::::::::::::::::::::: XP_005 MVRSHYVTETLSEEEAGFPLAYTVTIHKDF 10 20 30 110 120 130 140 150 160 pF1KF0 GTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRL 40 50 60 70 80 90 170 180 190 200 210 220 pF1KF0 QADLNCLEDLVASEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QADLNCLEDLVASEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KF0 RTKYVHQELLNHKNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTKYVHQELLNHKNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KF0 SWSKDTYSPDEHFWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SWSKDTYSPDEHFWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGIC 220 230 240 250 260 270 350 360 370 380 390 400 pF1KF0 IYGNGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IYGNGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF 280 290 300 310 320 >>XP_016866221 (OMIM: 110800,116700,600429) PREDICTED: N (318 aa) initn: 2077 init1: 2077 opt: 2077 Z-score: 2613.7 bits: 492.2 E(85289): 7.6e-139 Smith-Waterman score: 2077; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS ::::::::: XP_016 WVTLNRIPGQKTEGTLAI 310 >>XP_011512770 (OMIM: 110800,116700,600429) PREDICTED: N (318 aa) initn: 2077 init1: 2077 opt: 2077 Z-score: 2613.7 bits: 492.2 E(85289): 7.6e-139 Smith-Waterman score: 2077; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309) 10 20 30 40 50 60 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS ::::::::: XP_011 WVTLNRIPGQKTEGTLAI 310 >>NP_663630 (OMIM: 110800,116700,600429) N-acetyllactosa (402 aa) initn: 1969 init1: 1969 opt: 2047 Z-score: 2574.5 bits: 485.3 E(85289): 1.2e-136 Smith-Waterman score: 2047; 73.1% identity (87.6% similar) in 402 aa overlap (2-402:1-402) 10 20 30 40 50 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAE-ACHQIFEGKVFY :. :..:.:. .:.:..::: :...: : . . :. . . ::.. .: . NP_663 MNFWRYCFFAFTLLSVVIFVRFYSSQLSPPKSYEKLNSSSERYFRKTACNHALEKMPVF 10 20 30 40 50 60 70 80 90 100 110 pF1KF0 PTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYM :: : . : . : .:....::.: ::::::.:::::...::::: ::::::::::: NP_663 LWENILPSPLRSVPCKDYLTQNHYITSPLSEEEAAFPLAYVMVIHKDFDTFERLFRAIYM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KF0 PQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVA ::::::::.:.:: .: .:.:::::: :::.::: :::::.::::::::::::.:::: NP_663 PQNVYCVHVDEKAPAEYKESVRQLLSCFQNAFIASKTESVVYAGISRLQADLNCLKDLVA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KF0 SEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNH ::::::::::::::::::::::::::.:::::::::::::::::::. :::::::: .. NP_663 SEVPWKYVINTCGQDFPLKTNREIVQHLKGFKGKNITPGVLPPDHAIKRTKYVHQEHTDK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KF0 KNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEH . .: .:. ::: :::...::::::::::::::..:::.:: :.:::.::::::::::: NP_663 GGFFVKNTNILKTSPPHQLTIYFGTAYVALTRDFVDFVLRDQRAIDLLQWSKDTYSPDEH 240 250 260 270 280 290 300 310 320 330 340 350 pF1KF0 FWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVN :::::::. ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_663 FWVTLNRVSGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVN 300 310 320 330 340 350 360 370 380 390 400 pF1KF0 SPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF ::::::::::::::::::::::::::::::::::::::::::: NP_663 SPSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF 360 370 380 390 400 >>NP_001482 (OMIM: 110800,116700,600429) N-acetyllactosa (400 aa) initn: 1959 init1: 1959 opt: 2014 Z-score: 2533.0 bits: 477.6 E(85289): 2.4e-134 Smith-Waterman score: 2014; 73.9% identity (87.3% similar) in 394 aa overlap (9-402:8-400) 10 20 30 40 50 60 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP :: :. :..::. .. . : : .:. :...: ....::. . NP_001 MPLSMRYLFIISVSSVIIFIVFSVFNFGGDPSFQRLNISDPLRLTQVCTSFINGKTRFL 10 20 30 40 50 70 80 90 100 110 120 pF1KF0 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP .: : ....: ::...:::.: ::.::: ::::: ..::. : :: ::::::::: NP_001 WKNKL-MIHEKSSCKEYLTQSHYITAPLSKEEADFPLAYIMVIHHHFDTFARLFRAIYMP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KF0 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS ::.::::.:.::: :: ::.:::::::::::::: : :::::::::::::::..:: : NP_001 QNIYCVHVDEKATTEFKDAVEQLLSCFPNAFLASKMEPVVYGGISRLQADLNCIRDLSAF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KF0 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK :: :::::::::::::::::.::::::::::::::::::::: ::.::::::::: :... NP_001 EVSWKYVINTCGQDFPLKTNKEIVQYLKGFKGKNITPGVLPPAHAIGRTKYVHQEHLGKE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KF0 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF ::::.:: :: ::::...::::.:::::.:.::::::.: :.:::.:::::.:::::: NP_001 LSYVIRTTALKPPPPHNLTIYFGSAYVALSREFANFVLHDPRAVDLLQWSKDTFSPDEHF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KF0 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS 300 310 320 330 340 350 370 380 390 400 pF1KF0 PSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF :::::::::::::::::::::::::::::::::::::::::: NP_001 PSLFANKFELNTYPLTVECLELRHRERTLNQSETAIQPSWYF 360 370 380 390 400 >>XP_011512768 (OMIM: 110800,116700,600429) PREDICTED: N (339 aa) initn: 1294 init1: 1294 opt: 1387 Z-score: 1745.5 bits: 331.6 E(85289): 1.7e-90 Smith-Waterman score: 1387; 63.5% identity (83.0% similar) in 323 aa overlap (2-323:1-321) 10 20 30 40 50 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAE-ACHQIFEGKVFY :. :..:.:. .:.:..::: :...: : . . :. . . ::.. .: . XP_011 MNFWRYCFFAFTLLSVVIFVRFYSSQLSPPKSYEKLNSSSERYFRKTACNHALEKMPVF 10 20 30 40 50 60 70 80 90 100 110 pF1KF0 PTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYM :: : . : . : .:....::.: ::::::.:::::...::::: ::::::::::: XP_011 LWENILPSPLRSVPCKDYLTQNHYITSPLSEEEAAFPLAYVMVIHKDFDTFERLFRAIYM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KF0 PQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVA ::::::::.:.:: .: .:.:::::: :::.::: :::::.::::::::::::.:::: XP_011 PQNVYCVHVDEKAPAEYKESVRQLLSCFQNAFIASKTESVVYAGISRLQADLNCLKDLVA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KF0 SEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNH ::::::::::::::::::::::::::.:::::::::::::::::::. :::::::: .. XP_011 SEVPWKYVINTCGQDFPLKTNREIVQHLKGFKGKNITPGVLPPDHAIKRTKYVHQEHTDK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KF0 KNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEH . .: .:. ::: :::...::::::::::::::..:::.:: :.:::.::::::::::: XP_011 GGFFVKNTNILKTSPPHQLTIYFGTAYVALTRDFVDFVLRDQRAIDLLQWSKDTYSPDEH 240 250 260 270 280 290 300 310 320 330 340 350 pF1KF0 FWVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVN :::::::. :. :. :.::.. XP_011 FWVTLNRVSDSPS--PSHSFTGQVLLQILLKCVLRTKQGSFL 300 310 320 330 >>XP_005249054 (OMIM: 110800,116700,600429) PREDICTED: N (363 aa) initn: 1277 init1: 1277 opt: 1332 Z-score: 1675.9 bits: 318.8 E(85289): 1.3e-86 Smith-Waterman score: 1332; 65.7% identity (83.3% similar) in 300 aa overlap (9-308:8-306) 10 20 30 40 50 60 pF1KF0 MMGSWKHCLFSASLISALIFVFVYNTELWENKRFLRAALSNASLLAEACHQIFEGKVFYP :: :. :..::. .. . : : .:. :...: ....::. . XP_005 MPLSMRYLFIISVSSVIIFIVFSVFNFGGDPSFQRLNISDPLRLTQVCTSFINGKTRFL 10 20 30 40 50 70 80 90 100 110 120 pF1KF0 TENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTIHKDFGTFERLFRAIYMP .: : ....: ::...:::.: ::.::: ::::: ..::. : :: ::::::::: XP_005 WKNKLMIH-EKSSCKEYLTQSHYITAPLSKEEADFPLAYIMVIHHHFDTFARLFRAIYMP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KF0 QNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGGISRLQADLNCLEDLVAS ::.::::.:.::: :: ::.:::::::::::::: : :::::::::::::::..:: : XP_005 QNIYCVHVDEKATTEFKDAVEQLLSCFPNAFLASKMEPVVYGGISRLQADLNCIRDLSAF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KF0 EVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPDHAVGRTKYVHQELLNHK :: :::::::::::::::::.::::::::::::::::::::: ::.::::::::: :... XP_005 EVSWKYVINTCGQDFPLKTNKEIVQYLKGFKGKNITPGVLPPAHAIGRTKYVHQEHLGKE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KF0 NSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLALDLLSWSKDTYSPDEHF ::::.:: :: ::::...::::.:::::.:.::::::.: :.:::.:::::.:::::: XP_005 LSYVIRTTALKPPPPHNLTIYFGSAYVALSREFANFVLHDPRAVDLLQWSKDTFSPDEHF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KF0 WVTLNRIPGVPGSMPNASWTGNLRAIKWSDMEDRHGGCHGHYVHGICIYGNGDLKWLVNS :::::::: XP_005 WVTLNRIPVFGRYKGWDVLDMDLWQQLDCQIVSLGTSQLLFPRMRHSESEKSCCAERQIV 300 310 320 330 340 350 >>NP_004742 (OMIM: 606836) beta-1,3-galactosyl-O-glycosy (438 aa) initn: 948 init1: 589 opt: 984 Z-score: 1237.1 bits: 237.9 E(85289): 3.6e-62 Smith-Waterman score: 984; 43.7% identity (73.5% similar) in 332 aa overlap (74-393:110-437) 50 60 70 80 90 100 pF1KF0 LLAEACHQIFEGKVFYPTENALKTTLDEATCYEYMVRSHYVTETLSEEEAGFPLAYTVTI : .. .. ... ::.::. ::.::...: NP_004 AVLQAILNNLEVKKKREPFTDTHYLSLTRDCEHFKAERKFIQFPLSKEEVEFPIAYSMVI 80 90 100 110 120 130 110 120 130 140 150 160 pF1KF0 HKDFGTFERLFRAIYMPQNVYCVHLDQKATDAFKGAVKQLLSCFPNAFLASKKESVVYGG :. . .::::.::.: :::.::::.:.:. ..:: ::: ..:::::.:.::: :::.. NP_004 HEKIENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAIISCFPNVFIASKLVRVVYAS 140 150 160 170 180 190 170 180 190 200 210 220 pF1KF0 ISRLQADLNCLEDLVASEVPWKYVINTCGQDFPLKTNREIVQYLKGFKGKNITPGVLPPD ::.::::::.:::. : ::::: .:::: :::.:.: :.:: :: ..:.: . .:: NP_004 WSRVQADLNCMEDLLQSSVPWKYFLNTCGTDFPIKSNAEMVQALKMLNGRNSMESEVPPK 200 210 220 230 240 250 230 240 250 260 270 280 pF1KF0 HAVGRTKYVHQELLNHKNSYVIKTTKLKTPPPHDMVIYFGTAYVALTRDFANFVLQDQLA : : :: : :.. ... . :.: : :::...... :.::.. .:::.. ::.. . NP_004 HKETRWKY-HFEVV--RDTLHL-TNKKKDPPPYNLTMFTGNAYIVASRDFVQHVLKNPKS 260 270 280 290 300 310 290 300 310 320 330 pF1KF0 LDLLSWSKDTYSPDEHFWVTLNRIPGVPGSMPN------ASWTGNLRAIKWSDME---DR .:. : :::::::::.:.::.: .:::.:: .. :. : .::. : :. NP_004 QQLIEWVKDTYSPDEHLWATLQRARWMPGSVPNHPKYDISDMTSIARLVKWQGHEGDIDK 320 330 340 350 360 370 340 350 360 370 380 390 pF1KF0 ---HGGCHGHYVHGICIYGNGDLKWLVNSPSLFANKFELNTYPLTVECLELRHRERTLNQ .. : : . ..::.:: :::.:.... :.::::. .. ...::: : ... NP_004 GAPYAPCSGIHQRAICVYGAGDLNWMLQNHHLLANKFDPKVDDNALQCLEEYLRYKAIYG 380 390 400 410 420 430 400 pF1KF0 SETAIQPSWYF .: NP_004 TEL 402 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:27:23 2016 done: Thu Nov 3 19:27:25 2016 Total Scan time: 8.340 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]