FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0417, 539 aa 1>>>pF1KF0417 539 - 539 aa - 539 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8116+/-0.000858; mu= 6.2823+/- 0.052 mean_var=275.9677+/-56.106, 0's: 0 Z-trim(116.3): 51 B-trim: 120 in 1/52 Lambda= 0.077205 statistics sampled from 16913 (16962) to 16913 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.521), width: 16 Scan time: 4.230 The best scores are: opt bits E(32554) CCDS59959.1 PLCH2 gene_id:9651|Hs108|chr1 (1416) 1434 173.2 1.8e-42 CCDS33881.1 PLCH1 gene_id:23007|Hs108|chr3 (1655) 774 99.8 2.7e-20 CCDS46940.1 PLCH1 gene_id:23007|Hs108|chr3 (1002) 618 82.2 3.2e-15 CCDS46939.1 PLCH1 gene_id:23007|Hs108|chr3 (1693) 618 82.4 4.6e-15 >>CCDS59959.1 PLCH2 gene_id:9651|Hs108|chr1 (1416 aa) initn: 1434 init1: 1395 opt: 1434 Z-score: 876.0 bits: 173.2 E(32554): 1.8e-42 Smith-Waterman score: 1463; 54.9% identity (65.8% similar) in 506 aa overlap (79-527:753-1240) 50 60 70 80 90 100 pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY :.. ... . : : :.. . :.: . .: CCDS59 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR- 730 740 750 760 770 780 110 120 130 140 150 160 pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD : . :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD 790 800 810 820 830 170 180 190 200 210 220 pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL 840 850 860 870 880 890 230 240 250 260 270 280 pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV 900 910 920 930 940 950 290 300 310 320 330 pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLD--------GPG ::::::::::::::::::::::::::: : .. . : :: :. ::: CCDS59 ADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLP----PLCSLETIAEEPAPGPG 960 970 980 990 1000 1010 340 350 360 370 pF1KF0 PAGMAATCMKCV-------VGSCAGVNTGGLQRERP----PSP-------GPASR----Q : ::. . .: :.: . . :.: : : : : : CCDS59 PPPPAAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQ 1020 1030 1040 1050 1060 1070 380 390 400 410 420 pF1KF0 AAIRQQPRA--------RADSLGA----PCCGLDPHAIP----GRSREAPKGPGAW-RQG . :.:::. :. : : : : : : : . .: . : : CCDS59 TDGRSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLE 1080 1090 1100 1110 1120 1130 430 440 450 460 470 pF1KF0 P-GGSGSMSSDSSSPDSPGIPERS-PRWPEGACRQ--PGALQGEMSALFAQKLEEIRSKS : : :.::.:: .: . . : : : :. :: .:.. : .: CCDS59 PCGHRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPP---------RPHS 1140 1150 1160 1170 1180 480 490 500 510 520 530 pF1KF0 PMFSAGKPLLPCVVLPHA-PGMAGPGS----PAAASAWTVSPRVLVLVALYPWHCLRGTL ::..: :: :. .. :.. . :. : . ...::. : :: :: CCDS59 A--SAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVG 1190 1200 1210 1220 1230 1240 pF1KF0 LPWLACGP CCDS59 VQDCPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLR 1250 1260 1270 1280 1290 1300 >-- initn: 603 init1: 543 opt: 543 Z-score: 339.7 bits: 74.0 E(32554): 1.3e-12 Smith-Waterman score: 544; 73.9% identity (82.6% similar) in 115 aa overlap (20-115:4-118) 10 20 30 40 pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESR------WL-----FLSANIL--------PVVER : :.:.:: :: ....... :.::: CCDS59 MSGPWPSPDSRTKGTVAWLAEVLLWVGGSVVLSSEWQLGPLVER 10 20 30 40 50 60 70 80 90 100 pF1KF0 CMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 CMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQ 50 60 70 80 90 100 110 120 130 140 150 160 pF1KF0 SEVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALV :::::::::::::: CCDS59 SEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLA 110 120 130 140 150 160 >>CCDS33881.1 PLCH1 gene_id:23007|Hs108|chr3 (1655 aa) initn: 762 init1: 673 opt: 774 Z-score: 477.9 bits: 99.8 E(32554): 2.7e-20 Smith-Waterman score: 774; 58.8% identity (79.9% similar) in 204 aa overlap (93-289:717-914) 70 80 90 100 110 pF1KF0 VRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSF-------DP : .: :.: . . ::. : :: CCDS33 GYVLKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQ---LPKPPDSMFGDRGEIIDP 690 700 710 720 730 740 120 130 140 150 160 170 pF1KF0 FVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDF ::::::::::::: ..::::::::::::.:::::.: ::::::::::::::::::::::: CCDS33 FVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDF 750 760 770 780 790 800 180 190 200 210 220 230 pF1KF0 IGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSL .::::..:::..::::::::::. :::::::.....: :: .: :::::: ..:. .: CCDS33 VGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIYGKNRQLQGLKGLFNKNPRHSS- 810 820 830 840 850 860 240 250 260 270 280 290 pF1KF0 DSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDVVPPG :. .. . :...::::::::::.:..: .. :: :.: .:. :... : CCDS33 -SENNSHYVRKRSIGDRILRRTASAPAKGRKKSKMGFQEMVE-IKDSVSEATRDQDGVLR 870 880 890 900 910 920 300 310 320 330 340 350 pF1KF0 PGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCVVGSC CCDS33 RTTRSLQARPVSMPVDRNLLGALSLPVSETAKDIEGKENSLAEDKDGRRKGKASIKDPHF 930 940 950 960 970 980 >>CCDS46940.1 PLCH1 gene_id:23007|Hs108|chr3 (1002 aa) initn: 745 init1: 613 opt: 618 Z-score: 386.7 bits: 82.2 E(32554): 3.2e-15 Smith-Waterman score: 724; 53.6% identity (72.8% similar) in 224 aa overlap (93-289:735-952) 70 80 90 100 110 pF1KF0 VRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSF-------DP : .: :.: . . ::. : :: CCDS46 GYVLKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQ---LPKPPDSMFGDRGEIIDP 710 720 730 740 750 760 120 130 140 150 160 170 pF1KF0 FVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDF ::::::::::::: ..::::::::::::.:::::.: ::::::::::::::::::::::: CCDS46 FVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDF 770 780 790 800 810 820 180 190 200 210 pF1KF0 IGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKV------------------- .::::..:::..::::::::::. :::::::.....: :: CCDS46 VGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIYGKWSPLILNPSYTILHFLGATK 830 840 850 860 870 880 220 230 240 250 260 270 pF1KF0 -KQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPEL .: :::::: ..:. .: :. .. . :...::::::::::.:..: .. :: :. CCDS46 NRQLQGLKGLFNKNPRHSS--SENNSHYVRKRSIGDRILRRTASAPAKGRKKSKMGFQEM 890 900 910 920 930 280 290 300 310 320 330 pF1KF0 VLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVL : .:. :... : CCDS46 VE-IKDSVSEATRDQDGVLRRTTRSLQARPVSMPVDRNLLGALSLPVSETAKDIEGKENS 940 950 960 970 980 990 >>CCDS46939.1 PLCH1 gene_id:23007|Hs108|chr3 (1693 aa) initn: 745 init1: 613 opt: 618 Z-score: 383.9 bits: 82.4 E(32554): 4.6e-15 Smith-Waterman score: 724; 53.6% identity (72.8% similar) in 224 aa overlap (93-289:735-952) 70 80 90 100 110 pF1KF0 VRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSF-------DP : .: :.: . . ::. : :: CCDS46 GYVLKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQ---LPKPPDSMFGDRGEIIDP 710 720 730 740 750 760 120 130 140 150 160 170 pF1KF0 FVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDF ::::::::::::: ..::::::::::::.:::::.: ::::::::::::::::::::::: CCDS46 FVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDF 770 780 790 800 810 820 180 190 200 210 pF1KF0 IGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKV------------------- .::::..:::..::::::::::. :::::::.....: :: CCDS46 VGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIYGKWSPLILNPSYTILHFLGATK 830 840 850 860 870 880 220 230 240 250 260 270 pF1KF0 -KQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPEL .: :::::: ..:. .: :. .. . :...::::::::::.:..: .. :: :. CCDS46 NRQLQGLKGLFNKNPRHSS--SENNSHYVRKRSIGDRILRRTASAPAKGRKKSKMGFQEM 890 900 910 920 930 280 290 300 310 320 330 pF1KF0 VLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVL : .:. :... : CCDS46 VE-IKDSVSEATRDQDGVLRRTTRSLQARPVSMPVDRNLLGALSLPVSETAKDIEGKENS 940 950 960 970 980 990 539 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:37:42 2016 done: Sat Nov 5 06:37:43 2016 Total Scan time: 4.230 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]