Result of FASTA (omim) for
pF1KF0417
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KF0417, 539 aa
1>>>pF1KF0417 539 - 539 aa - 539 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0201+/-0.000361; mu= -1.3563+/- 0.022
mean_var=320.8215+/-66.370, 0's: 0 Z-trim(123.7): 143 B-trim: 330 in 1/57
Lambda= 0.071605
statistics sampled from 43899 (44081) to 43899 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.517), width: 16
Scan time: 12.860
The best scores are: opt bits E(85289)
XP_011540757 (OMIM: 612836) PREDICTED: 1-phosphati (1580) 2573 279.8 4.3e-74
XP_011540758 (OMIM: 612836) PREDICTED: 1-phosphati (1580) 2573 279.8 4.3e-74
XP_016858360 (OMIM: 612836) PREDICTED: 1-phosphati (1670) 2573 279.8 4.5e-74
XP_016858359 (OMIM: 612836) PREDICTED: 1-phosphati (1678) 2573 279.8 4.5e-74
NP_001289941 (OMIM: 612836) 1-phosphatidylinositol (1129) 2565 278.8 6e-74
NP_055453 (OMIM: 612836) 1-phosphatidylinositol 4, (1416) 1434 162.1 1e-38
XP_016858362 (OMIM: 612836) PREDICTED: 1-phosphati (1475) 1434 162.1 1.1e-38
XP_016858361 (OMIM: 612836) PREDICTED: 1-phosphati (1511) 1434 162.1 1.1e-38
NP_001289942 (OMIM: 612836) 1-phosphatidylinositol (1019) 1403 158.8 7.6e-38
XP_016858363 (OMIM: 612836) PREDICTED: 1-phosphati (1094) 1403 158.8 8e-38
NP_055811 (OMIM: 612835) 1-phosphatidylinositol 4, (1655) 774 94.0 3.9e-18
XP_005247296 (OMIM: 612835) PREDICTED: 1-phosphati (1673) 774 94.0 3.9e-18
XP_016861413 (OMIM: 612835) PREDICTED: 1-phosphati (1684) 774 94.0 4e-18
XP_011510866 (OMIM: 612835) PREDICTED: 1-phosphati (1685) 774 94.0 4e-18
XP_016861418 (OMIM: 612835) PREDICTED: 1-phosphati (1002) 618 77.7 1.9e-13
NP_001124433 (OMIM: 612835) 1-phosphatidylinositol (1002) 618 77.7 1.9e-13
XP_011510869 (OMIM: 612835) PREDICTED: 1-phosphati (1014) 618 77.7 1.9e-13
XP_016861417 (OMIM: 612835) PREDICTED: 1-phosphati (1014) 618 77.7 1.9e-13
XP_016861416 (OMIM: 612835) PREDICTED: 1-phosphati (1021) 618 77.7 2e-13
XP_011510867 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 618 77.9 2.8e-13
XP_016861415 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 618 77.9 2.8e-13
XP_011510868 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 618 77.9 2.8e-13
XP_016861414 (OMIM: 612835) PREDICTED: 1-phosphati (1681) 618 77.9 2.8e-13
NP_001124432 (OMIM: 612835) 1-phosphatidylinositol (1693) 618 77.9 2.8e-13
XP_016861412 (OMIM: 612835) PREDICTED: 1-phosphati (1704) 618 77.9 2.8e-13
XP_011510864 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 618 77.9 2.8e-13
XP_011510863 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 618 77.9 2.8e-13
XP_005247295 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 618 77.9 2.8e-13
XP_011510862 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 618 77.9 2.8e-13
XP_016859829 (OMIM: 600597) PREDICTED: inactive ph ( 997) 356 50.6 2.7e-05
XP_005246701 (OMIM: 600597) PREDICTED: inactive ph (1016) 356 50.6 2.7e-05
XP_011509653 (OMIM: 600597) PREDICTED: inactive ph (1016) 356 50.6 2.7e-05
XP_016859828 (OMIM: 600597) PREDICTED: inactive ph (1016) 356 50.6 2.7e-05
XP_005246700 (OMIM: 600597) PREDICTED: inactive ph (1021) 356 50.6 2.8e-05
NP_006217 (OMIM: 600597) inactive phospholipase C- (1095) 356 50.6 2.9e-05
NP_116115 (OMIM: 605939) 1-phosphatidylinositol 4, ( 762) 338 48.6 8.1e-05
XP_016860605 (OMIM: 605939) PREDICTED: 1-phosphati ( 794) 338 48.6 8.3e-05
NP_055999 (OMIM: 614276) inactive phospholipase C- (1001) 339 48.8 9.2e-05
XP_016861514 (OMIM: 614276) PREDICTED: inactive ph (1001) 339 48.8 9.2e-05
XP_006713136 (OMIM: 614276) PREDICTED: inactive ph (1022) 339 48.8 9.3e-05
XP_016861513 (OMIM: 614276) PREDICTED: inactive ph (1127) 339 48.9 0.0001
XP_016861512 (OMIM: 614276) PREDICTED: inactive ph (1127) 339 48.9 0.0001
NP_001137854 (OMIM: 614276) inactive phospholipase (1127) 339 48.9 0.0001
XP_016861511 (OMIM: 614276) PREDICTED: inactive ph (1127) 339 48.9 0.0001
NP_588614 (OMIM: 608795) 1-phosphatidylinositol 4, ( 789) 331 47.9 0.00014
XP_016875675 (OMIM: 608075) PREDICTED: 1-phosphati ( 359) 316 46.0 0.00023
XP_016875674 (OMIM: 608075) PREDICTED: 1-phosphati ( 400) 316 46.1 0.00025
XP_016875673 (OMIM: 608075) PREDICTED: 1-phosphati ( 422) 316 46.1 0.00026
XP_016875672 (OMIM: 608075) PREDICTED: 1-phosphati ( 466) 316 46.1 0.00027
XP_016875671 (OMIM: 608075) PREDICTED: 1-phosphati ( 471) 316 46.2 0.00028
>>XP_011540757 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1580 aa)
initn: 2591 init1: 2555 opt: 2573 Z-score: 1451.2 bits: 279.8 E(85289): 4.3e-74
Smith-Waterman score: 2590; 88.0% identity (91.6% similar) in 440 aa overlap (79-505:750-1185)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
XP_011 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR-
720 730 740 750 760 770
110 120 130 140 150 160
pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
780 790 800 810 820 830
170 180 190 200 210 220
pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
840 850 860 870 880 890
230 240 250 260 270 280
pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
900 910 920 930 940 950
290 300 310 320 330 340
pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATC
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_011 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATC
960 970 980 990 1000 1010
350 360 370 380 390 400
pF1KF0 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
1020 1030 1040 1050 1060 1070
410 420 430 440 450 460
pF1KF0 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
1080 1090 1100 1110 1120 1130
470 480 490 500 510
pF1KF0 KLEEIRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRV
:::::::::::::: .:: : : .. ::: :: :::
XP_011 KLEEIRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRP
1140 1150 1160 1170 1180 1190
520 530
pF1KF0 LVLVALYPWHCLRGTLLPWLACGP
XP_011 PYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVI
1200 1210 1220 1230 1240 1250
>--
initn: 861 init1: 815 opt: 815 Z-score: 469.7 bits: 98.2 E(85289): 2e-19
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 115 aa overlap (1-115:1-115)
10 20 30 40 50 60
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLFLSANILPVVERCMGAMQEGMQMVKLRGGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMAPPTAGPLPGPALPPEDPGPDPESRWLFLSANILPVVERCMGAMQEGMQMVKLRGGSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KF0 GLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPFVEVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNCCFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KF0 IIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRT
XP_011 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
130 140 150 160 170 180
>>XP_011540758 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1580 aa)
initn: 2591 init1: 2555 opt: 2573 Z-score: 1451.2 bits: 279.8 E(85289): 4.3e-74
Smith-Waterman score: 2590; 88.0% identity (91.6% similar) in 440 aa overlap (79-505:750-1185)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
XP_011 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR-
720 730 740 750 760 770
110 120 130 140 150 160
pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
780 790 800 810 820 830
170 180 190 200 210 220
pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
840 850 860 870 880 890
230 240 250 260 270 280
pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
900 910 920 930 940 950
290 300 310 320 330 340
pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATC
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_011 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATC
960 970 980 990 1000 1010
350 360 370 380 390 400
pF1KF0 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
1020 1030 1040 1050 1060 1070
410 420 430 440 450 460
pF1KF0 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
1080 1090 1100 1110 1120 1130
470 480 490 500 510
pF1KF0 KLEEIRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRV
:::::::::::::: .:: : : .. ::: :: :::
XP_011 KLEEIRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRP
1140 1150 1160 1170 1180 1190
520 530
pF1KF0 LVLVALYPWHCLRGTLLPWLACGP
XP_011 PYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVI
1200 1210 1220 1230 1240 1250
>--
initn: 861 init1: 815 opt: 815 Z-score: 469.7 bits: 98.2 E(85289): 2e-19
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 115 aa overlap (1-115:1-115)
10 20 30 40 50 60
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLFLSANILPVVERCMGAMQEGMQMVKLRGGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMAPPTAGPLPGPALPPEDPGPDPESRWLFLSANILPVVERCMGAMQEGMQMVKLRGGSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KF0 GLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPFVEVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNCCFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KF0 IIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRT
XP_011 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
130 140 150 160 170 180
>>XP_016858360 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1670 aa)
initn: 2591 init1: 2555 opt: 2573 Z-score: 1450.9 bits: 279.8 E(85289): 4.5e-74
Smith-Waterman score: 2590; 88.0% identity (91.6% similar) in 440 aa overlap (79-505:840-1275)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
XP_016 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR-
810 820 830 840 850 860
110 120 130 140 150 160
pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
870 880 890 900 910 920
170 180 190 200 210 220
pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
930 940 950 960 970 980
230 240 250 260 270 280
pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
990 1000 1010 1020 1030 1040
290 300 310 320 330 340
pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATC
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATC
1050 1060 1070 1080 1090 1100
350 360 370 380 390 400
pF1KF0 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
1110 1120 1130 1140 1150 1160
410 420 430 440 450 460
pF1KF0 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
1170 1180 1190 1200 1210 1220
470 480 490 500 510
pF1KF0 KLEEIRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRV
:::::::::::::: .:: : : .. ::: :: :::
XP_016 KLEEIRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRP
1230 1240 1250 1260 1270 1280
520 530
pF1KF0 LVLVALYPWHCLRGTLLPWLACGP
XP_016 PYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVI
1290 1300 1310 1320 1330 1340
>--
initn: 815 init1: 815 opt: 815 Z-score: 469.4 bits: 98.2 E(85289): 2.1e-19
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 115 aa overlap (1-115:91-205)
10 20 30
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLF
::::::::::::::::::::::::::::::
XP_016 LPPVDGRPQLVIPASPSFQLLPPPTVLSPSMMAPPTAGPLPGPALPPEDPGPDPESRWLF
70 80 90 100 110 120
40 50 60 70 80 90
pF1KF0 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
130 140 150 160 170 180
100 110 120 130 140 150
pF1KF0 DSIQEVSEGRQSEVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLV
:::::::::::::::::::::::::
XP_016 DSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYL
190 200 210 220 230 240
>>XP_016858359 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1678 aa)
initn: 2591 init1: 2555 opt: 2573 Z-score: 1450.9 bits: 279.8 E(85289): 4.5e-74
Smith-Waterman score: 2590; 88.0% identity (91.6% similar) in 440 aa overlap (79-505:848-1283)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
XP_016 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR-
820 830 840 850 860 870
110 120 130 140 150 160
pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
880 890 900 910 920 930
170 180 190 200 210 220
pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
940 950 960 970 980 990
230 240 250 260 270 280
pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
1000 1010 1020 1030 1040 1050
290 300 310 320 330 340
pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATC
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATC
1060 1070 1080 1090 1100 1110
350 360 370 380 390 400
pF1KF0 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS
1120 1130 1140 1150 1160 1170
410 420 430 440 450 460
pF1KF0 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ
1180 1190 1200 1210 1220 1230
470 480 490 500 510
pF1KF0 KLEEIRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRV
:::::::::::::: .:: : : .. ::: :: :::
XP_016 KLEEIRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRP
1240 1250 1260 1270 1280 1290
520 530
pF1KF0 LVLVALYPWHCLRGTLLPWLACGP
XP_016 PYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVI
1300 1310 1320 1330 1340 1350
>--
initn: 834 init1: 815 opt: 815 Z-score: 469.4 bits: 98.2 E(85289): 2.1e-19
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 115 aa overlap (1-115:99-213)
10 20 30
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLF
::::::::::::::::::::::::::::::
XP_016 LPPVDGRPQLVIPASPSFQLLPPPTVLSPSMMAPPTAGPLPGPALPPEDPGPDPESRWLF
70 80 90 100 110 120
40 50 60 70 80 90
pF1KF0 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
130 140 150 160 170 180
100 110 120 130 140 150
pF1KF0 DSIQEVSEGRQSEVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLV
:::::::::::::::::::::::::
XP_016 DSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYL
190 200 210 220 230 240
>>NP_001289941 (OMIM: 612836) 1-phosphatidylinositol 4,5 (1129 aa)
initn: 2555 init1: 2555 opt: 2565 Z-score: 1448.6 bits: 278.8 E(85289): 6e-74
Smith-Waterman score: 2565; 92.8% identity (96.0% similar) in 403 aa overlap (79-481:726-1126)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
NP_001 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRG
700 710 720 730 740 750
110 120 130 140 150 160
pF1KF0 PDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDH
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 E--IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDH
760 770 780 790 800 810
170 180 190 200 210 220
pF1KF0 DPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLR
820 830 840 850 860 870
230 240 250 260 270 280
pF1KF0 GPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVA
880 890 900 910 920 930
290 300 310 320 330 340
pF1KF0 DDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCM
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 DDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATCM
940 950 960 970 980 990
350 360 370 380 390 400
pF1KF0 KCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSR
1000 1010 1020 1030 1040 1050
410 420 430 440 450 460
pF1KF0 EAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQK
1060 1070 1080 1090 1100 1110
470 480 490 500 510 520
pF1KF0 LEEIRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSPRVLVLVALYPWHCLR
:::::::::::::
NP_001 LEEIRSKSPMFSAVRN
1120
>--
initn: 609 init1: 532 opt: 537 Z-score: 316.4 bits: 69.3 E(85289): 7e-11
Smith-Waterman score: 537; 85.7% identity (88.8% similar) in 98 aa overlap (18-115:2-91)
10 20 30 40 50 60
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLFLSANILPVVERCMGAMQEGMQMVKLRGGSK
:.::: : . :: . ::::::::::::::::::::::
NP_001 MEEPGP-PGG----LSQDQ---VERCMGAMQEGMQMVKLRGGSK
10 20 30
70 80 90 100 110 120
pF1KF0 GLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPFVEVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNCCFS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KF0 IIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRT
NP_001 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
100 110 120 130 140 150
>>NP_055453 (OMIM: 612836) 1-phosphatidylinositol 4,5-bi (1416 aa)
initn: 1434 init1: 1395 opt: 1434 Z-score: 815.9 bits: 162.1 E(85289): 1e-38
Smith-Waterman score: 1463; 54.9% identity (65.8% similar) in 506 aa overlap (79-527:753-1240)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
NP_055 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR-
730 740 750 760 770 780
110 120 130 140 150 160
pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
790 800 810 820 830
170 180 190 200 210 220
pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
840 850 860 870 880 890
230 240 250 260 270 280
pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
900 910 920 930 940 950
290 300 310 320 330
pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLD--------GPG
::::::::::::::::::::::::::: : .. . : :: :. :::
NP_055 ADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLP----PLCSLETIAEEPAPGPG
960 970 980 990 1000 1010
340 350 360 370
pF1KF0 PAGMAATCMKCV-------VGSCAGVNTGGLQRERP----PSP-------GPASR----Q
: ::. . .: :.: . . :.: : : : : :
NP_055 PPPPAAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQ
1020 1030 1040 1050 1060 1070
380 390 400 410 420
pF1KF0 AAIRQQPRA--------RADSLGA----PCCGLDPHAIP----GRSREAPKGPGAW-RQG
. :.:::. :. : : : : : : : . .: . : :
NP_055 TDGRSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLE
1080 1090 1100 1110 1120 1130
430 440 450 460 470
pF1KF0 P-GGSGSMSSDSSSPDSPGIPERS-PRWPEGACRQ--PGALQGEMSALFAQKLEEIRSKS
: : :.::.:: .: . . : : : :. :: .:.. : .:
NP_055 PCGHRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPP---------RPHS
1140 1150 1160 1170 1180
480 490 500 510 520 530
pF1KF0 PMFSAGKPLLPCVVLPHA-PGMAGPGS----PAAASAWTVSPRVLVLVALYPWHCLRGTL
::..: :: :. .. :.. . :. : . ...::. : :: ::
NP_055 A--SAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVG
1190 1200 1210 1220 1230 1240
pF1KF0 LPWLACGP
NP_055 VQDCPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLR
1250 1260 1270 1280 1290 1300
>--
initn: 603 init1: 543 opt: 543 Z-score: 318.5 bits: 70.1 E(85289): 5.3e-11
Smith-Waterman score: 544; 73.9% identity (82.6% similar) in 115 aa overlap (20-115:4-118)
10 20 30 40
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESR------WL-----FLSANIL--------PVVER
: :.:.:: :: ....... :.:::
NP_055 MSGPWPSPDSRTKGTVAWLAEVLLWVGGSVVLSSEWQLGPLVER
10 20 30 40
50 60 70 80 90 100
pF1KF0 CMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQ
50 60 70 80 90 100
110 120 130 140 150 160
pF1KF0 SEVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALV
::::::::::::::
NP_055 SEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLA
110 120 130 140 150 160
>>XP_016858362 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1475 aa)
initn: 1434 init1: 1395 opt: 1434 Z-score: 815.7 bits: 162.1 E(85289): 1.1e-38
Smith-Waterman score: 1463; 54.9% identity (65.8% similar) in 506 aa overlap (79-527:812-1299)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
XP_016 RVDSSNYNPQPFWNAGCQMGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR-
790 800 810 820 830 840
110 120 130 140 150 160
pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
850 860 870 880 890
170 180 190 200 210 220
pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
900 910 920 930 940 950
230 240 250 260 270 280
pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
960 970 980 990 1000 1010
290 300 310 320 330
pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLD--------GPG
::::::::::::::::::::::::::: : .. . : :: :. :::
XP_016 ADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLP----PLCSLETIAEEPAPGPG
1020 1030 1040 1050 1060 1070
340 350 360 370
pF1KF0 PAGMAATCMKCV-------VGSCAGVNTGGLQRERP----PSP-------GPASR----Q
: ::. . .: :.: . . :.: : : : : :
XP_016 PPPPAAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQ
1080 1090 1100 1110 1120 1130
380 390 400 410 420
pF1KF0 AAIRQQPRA--------RADSLGA----PCCGLDPHAIP----GRSREAPKGPGAW-RQG
. :.:::. :. : : : : : : : . .: . : :
XP_016 TDGRSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLE
1140 1150 1160 1170 1180 1190
430 440 450 460 470
pF1KF0 P-GGSGSMSSDSSSPDSPGIPERS-PRWPEGACRQ--PGALQGEMSALFAQKLEEIRSKS
: : :.::.:: .: . . : : : :. :: .:.. : .:
XP_016 PCGHRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPP---------RPHS
1200 1210 1220 1230 1240
480 490 500 510 520 530
pF1KF0 PMFSAGKPLLPCVVLPHA-PGMAGPGS----PAAASAWTVSPRVLVLVALYPWHCLRGTL
::..: :: :. .. :.. . :. : . ...::. : :: ::
XP_016 A--SAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVG
1250 1260 1270 1280 1290 1300
pF1KF0 LPWLACGP
XP_016 VQDCPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLR
1310 1320 1330 1340 1350 1360
>--
initn: 834 init1: 815 opt: 815 Z-score: 470.1 bits: 98.2 E(85289): 1.9e-19
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 115 aa overlap (1-115:99-213)
10 20 30
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLF
::::::::::::::::::::::::::::::
XP_016 LPPVDGRPQLVIPASPSFQLLPPPTVLSPSMMAPPTAGPLPGPALPPEDPGPDPESRWLF
70 80 90 100 110 120
40 50 60 70 80 90
pF1KF0 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
130 140 150 160 170 180
100 110 120 130 140 150
pF1KF0 DSIQEVSEGRQSEVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLV
:::::::::::::::::::::::::
XP_016 DSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYL
190 200 210 220 230 240
>>XP_016858361 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1511 aa)
initn: 1434 init1: 1395 opt: 1434 Z-score: 815.6 bits: 162.1 E(85289): 1.1e-38
Smith-Waterman score: 1463; 54.9% identity (65.8% similar) in 506 aa overlap (79-527:848-1335)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
XP_016 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR-
820 830 840 850 860 870
110 120 130 140 150 160
pF1KF0 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD
880 890 900 910 920 930
170 180 190 200 210 220
pF1KF0 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL
940 950 960 970 980 990
230 240 250 260 270 280
pF1KF0 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV
1000 1010 1020 1030 1040 1050
290 300 310 320 330
pF1KF0 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLD--------GPG
::::::::::::::::::::::::::: : .. . : :: :. :::
XP_016 ADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLP----PLCSLETIAEEPAPGPG
1060 1070 1080 1090 1100 1110
340 350 360 370
pF1KF0 PAGMAATCMKCV-------VGSCAGVNTGGLQRERP----PSP-------GPASR----Q
: ::. . .: :.: . . :.: : : : : :
XP_016 PPPPAAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQ
1120 1130 1140 1150 1160 1170
380 390 400 410 420
pF1KF0 AAIRQQPRA--------RADSLGA----PCCGLDPHAIP----GRSREAPKGPGAW-RQG
. :.:::. :. : : : : : : : . .: . : :
XP_016 TDGRSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLE
1180 1190 1200 1210 1220 1230
430 440 450 460 470
pF1KF0 P-GGSGSMSSDSSSPDSPGIPERS-PRWPEGACRQ--PGALQGEMSALFAQKLEEIRSKS
: : :.::.:: .: . . : : : :. :: .:.. : .:
XP_016 PCGHRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPP---------RPHS
1240 1250 1260 1270 1280
480 490 500 510 520 530
pF1KF0 PMFSAGKPLLPCVVLPHA-PGMAGPGS----PAAASAWTVSPRVLVLVALYPWHCLRGTL
::..: :: :. .. :.. . :. : . ...::. : :: ::
XP_016 A--SAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVG
1290 1300 1310 1320 1330
pF1KF0 LPWLACGP
XP_016 VQDCPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLR
1340 1350 1360 1370 1380 1390
>--
initn: 834 init1: 815 opt: 815 Z-score: 470.0 bits: 98.2 E(85289): 1.9e-19
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 115 aa overlap (1-115:99-213)
10 20 30
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLF
::::::::::::::::::::::::::::::
XP_016 LPPVDGRPQLVIPASPSFQLLPPPTVLSPSMMAPPTAGPLPGPALPPEDPGPDPESRWLF
70 80 90 100 110 120
40 50 60 70 80 90
pF1KF0 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
130 140 150 160 170 180
100 110 120 130 140 150
pF1KF0 DSIQEVSEGRQSEVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLV
:::::::::::::::::::::::::
XP_016 DSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYL
190 200 210 220 230 240
>>NP_001289942 (OMIM: 612836) 1-phosphatidylinositol 4,5 (1019 aa)
initn: 1911 init1: 1393 opt: 1403 Z-score: 800.5 bits: 158.8 E(85289): 7.6e-38
Smith-Waterman score: 1403; 86.4% identity (93.0% similar) in 243 aa overlap (79-321:773-1013)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
NP_001 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRG
750 760 770 780 790 800
110 120 130 140 150 160
pF1KF0 PDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDH
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 E--IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDH
810 820 830 840 850 860
170 180 190 200 210 220
pF1KF0 DPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLR
870 880 890 900 910 920
230 240 250 260 270 280
pF1KF0 GPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVA
930 940 950 960 970 980
290 300 310 320 330 340
pF1KF0 DDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCM
::::::::::::::::::::::::::. .: .:
NP_001 DDVVPPGPGPAPEAPAQEGPGSGSPRAATPPTVQPGNHR
990 1000 1010
350 360 370 380 390 400
pF1KF0 KCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSR
>--
initn: 581 init1: 532 opt: 533 Z-score: 314.7 bits: 68.9 E(85289): 8.6e-11
Smith-Waterman score: 533; 80.6% identity (83.5% similar) in 103 aa overlap (13-115:38-138)
10 20 30 40
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLFLSANILPVVERC
:: : .:: . : . ::::
NP_001 LSVSRCAGTEGVRPVCSWAGTADSGLDSLDPAAP--SPGTSYSRRLNGERRGEKERVERC
10 20 30 40 50 60
50 60 70 80 90 100
pF1KF0 MGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KF0 EVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVR
:::::::::::::
NP_001 EVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLAR
130 140 150 160 170 180
>>XP_016858363 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1094 aa)
initn: 2194 init1: 1393 opt: 1403 Z-score: 800.1 bits: 158.8 E(85289): 8e-38
Smith-Waterman score: 1403; 86.4% identity (93.0% similar) in 243 aa overlap (79-321:848-1088)
50 60 70 80 90 100
pF1KF0 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY
:.. ... . : : :.. . :.: . .:
XP_016 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRG
820 830 840 850 860 870
110 120 130 140 150 160
pF1KF0 PDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDH
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 E--IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDH
880 890 900 910 920 930
170 180 190 200 210 220
pF1KF0 DPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLR
940 950 960 970 980 990
230 240 250 260 270 280
pF1KF0 GPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVA
1000 1010 1020 1030 1040 1050
290 300 310 320 330 340
pF1KF0 DDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCM
::::::::::::::::::::::::::. .: .:
XP_016 DDVVPPGPGPAPEAPAQEGPGSGSPRAATPPTVQPGNHR
1060 1070 1080 1090
350 360 370 380 390 400
pF1KF0 KCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSR
>--
initn: 834 init1: 815 opt: 815 Z-score: 471.8 bits: 98.0 E(85289): 1.5e-19
Smith-Waterman score: 815; 100.0% identity (100.0% similar) in 115 aa overlap (1-115:99-213)
10 20 30
pF1KF0 MMAPPTAGPLPGPALPPEDPGPDPESRWLF
::::::::::::::::::::::::::::::
XP_016 LPPVDGRPQLVIPASPSFQLLPPPTVLSPSMMAPPTAGPLPGPALPPEDPGPDPESRWLF
70 80 90 100 110 120
40 50 60 70 80 90
pF1KF0 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSANILPVVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISI
130 140 150 160 170 180
100 110 120 130 140 150
pF1KF0 DSIQEVSEGRQSEVFQRYPDGSFDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLV
:::::::::::::::::::::::::
XP_016 DSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYL
190 200 210 220 230 240
539 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:37:43 2016 done: Sat Nov 5 06:37:45 2016
Total Scan time: 12.860 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]