Result of FASTA (omim) for
pF1KSDA0019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0019, 828 aa
1>>>pF1KSDA0019 828 - 828 aa - 828 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5593+/-0.000437; mu= -8.6297+/- 0.027
mean_var=340.1867+/-71.328, 0's: 0 Z-trim(120.6): 200 B-trim: 0 in 0/56
Lambda= 0.069537
statistics sampled from 35764 (35982) to 35764 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.422), width: 16
Scan time: 12.450
The best scores are: opt bits E(85289)
NP_055503 (OMIM: 605405) USP6 N-terminal-like prot ( 828) 5642 580.5 1e-164
NP_001073960 (OMIM: 605405) USP6 N-terminal-like p ( 845) 5630 579.3 2.4e-164
XP_016872460 (OMIM: 605405) PREDICTED: USP6 N-term ( 846) 5630 579.3 2.4e-164
XP_016872462 (OMIM: 605405) PREDICTED: USP6 N-term ( 851) 5630 579.4 2.4e-164
XP_006717605 (OMIM: 605405) PREDICTED: USP6 N-term ( 856) 5630 579.4 2.4e-164
XP_011518064 (OMIM: 605405) PREDICTED: USP6 N-term ( 856) 5630 579.4 2.4e-164
XP_011518065 (OMIM: 605405) PREDICTED: USP6 N-term ( 672) 4585 474.4 7.1e-133
XP_016872461 (OMIM: 605405) PREDICTED: USP6 N-term ( 672) 4585 474.4 7.1e-133
XP_011522361 (OMIM: 604334) PREDICTED: ubiquitin c ( 786) 918 106.6 4.5e-22
XP_011522360 (OMIM: 604334) PREDICTED: ubiquitin c (1031) 918 106.7 5.5e-22
XP_011522358 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
XP_011522356 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
XP_016880779 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
NP_004496 (OMIM: 604334) ubiquitin carboxyl-termin (1406) 918 106.8 7.1e-22
XP_011522354 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
XP_011522353 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
XP_011522357 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
XP_011522355 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
XP_011522352 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 918 106.8 7.1e-22
NP_001291213 (OMIM: 604334) ubiquitin carboxyl-ter (1406) 918 106.8 7.1e-22
NP_001001417 (OMIM: 610144) TBC1 domain family mem ( 549) 863 101.0 1.5e-20
NP_115634 (OMIM: 610809) TBC1 domain family member ( 549) 860 100.7 1.9e-20
XP_016885746 (OMIM: 610806) PREDICTED: TBC1 domain ( 549) 859 100.6 2e-20
NP_001001418 (OMIM: 610806) TBC1 domain family mem ( 549) 858 100.5 2.2e-20
NP_001116863 (OMIM: 607741) TBC1 domain family mem ( 549) 858 100.5 2.2e-20
NP_001278391 (OMIM: 610810) TBC1 domain family mem ( 549) 856 100.3 2.5e-20
XP_006722317 (OMIM: 610808) PREDICTED: TBC1 domain ( 549) 853 100.0 3.1e-20
NP_001278395 (OMIM: 610808) TBC1 domain family mem ( 549) 853 100.0 3.1e-20
NP_001116864 (OMIM: 610811) TBC1 domain family mem ( 549) 850 99.7 3.8e-20
XP_006722118 (OMIM: 610811) PREDICTED: TBC1 domain ( 549) 850 99.7 3.8e-20
XP_005258037 (OMIM: 610144) PREDICTED: TBC1 domain ( 610) 792 93.9 2.3e-18
XP_005258038 (OMIM: 610806) PREDICTED: TBC1 domain ( 610) 788 93.5 3.1e-18
XP_011523116 (OMIM: 610806) PREDICTED: TBC1 domain ( 610) 787 93.4 3.3e-18
XP_006721967 (OMIM: 610806) PREDICTED: TBC1 domain ( 610) 787 93.4 3.3e-18
XP_005276971 (OMIM: 610810) PREDICTED: TBC1 domain ( 610) 785 93.2 3.8e-18
XP_011523475 (OMIM: 610811) PREDICTED: TBC1 domain ( 610) 779 92.6 5.7e-18
XP_011523474 (OMIM: 610811) PREDICTED: TBC1 domain ( 610) 779 92.6 5.7e-18
XP_011522359 (OMIM: 604334) PREDICTED: ubiquitin c (1384) 704 85.3 2e-15
XP_006721971 (OMIM: 610806) PREDICTED: TBC1 domain ( 390) 679 82.4 4.2e-15
XP_011545761 (OMIM: 610806) PREDICTED: TBC1 domain ( 559) 681 82.7 4.9e-15
XP_011523478 (OMIM: 610811) PREDICTED: TBC1 domain ( 390) 675 82.0 5.5e-15
XP_016880135 (OMIM: 610806) PREDICTED: TBC1 domain ( 559) 673 81.9 8.5e-15
XP_011523477 (OMIM: 610811) PREDICTED: TBC1 domain ( 559) 669 81.5 1.1e-14
XP_006721970 (OMIM: 610806) PREDICTED: TBC1 domain ( 527) 650 79.6 4e-14
XP_006722119 (OMIM: 610811) PREDICTED: TBC1 domain ( 527) 646 79.2 5.3e-14
XP_006721968 (OMIM: 610806) PREDICTED: TBC1 domain ( 588) 579 72.5 6.1e-12
XP_011523476 (OMIM: 610811) PREDICTED: TBC1 domain ( 588) 575 72.1 8.1e-12
XP_016857774 (OMIM: 602942) PREDICTED: ecotropic v ( 741) 525 67.2 3.1e-10
XP_016857773 (OMIM: 602942) PREDICTED: ecotropic v ( 777) 525 67.2 3.3e-10
XP_016857772 (OMIM: 602942) PREDICTED: ecotropic v ( 785) 525 67.2 3.3e-10
>>NP_055503 (OMIM: 605405) USP6 N-terminal-like protein (828 aa)
initn: 5642 init1: 5642 opt: 5642 Z-score: 3078.3 bits: 580.5 E(85289): 1e-164
Smith-Waterman score: 5642; 100.0% identity (100.0% similar) in 828 aa overlap (1-828:1-828)
10 20 30 40 50 60
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD RTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD DGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD NKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD GTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAV
730 740 750 760 770 780
790 800 810 820
pF1KSD SVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL
790 800 810 820
>>NP_001073960 (OMIM: 605405) USP6 N-terminal-like prote (845 aa)
initn: 5630 init1: 5630 opt: 5630 Z-score: 3071.6 bits: 579.3 E(85289): 2.4e-164
Smith-Waterman score: 5630; 99.9% identity (100.0% similar) in 827 aa overlap (2-828:19-845)
10 20 30 40
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYK
.:::::::::::::::::::::::::::::::::::::::::
NP_001 MRTEAVVNSQGQTDYLTKDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD VTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD QLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD VKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD FVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLR
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD IWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQ
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD ISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD ESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD YNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD EVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALYP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD PSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSP
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD KHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPV
670 680 690 700 710 720
710 720 730 740 750 760
pF1KSD DTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPK
730 740 750 760 770 780
770 780 790 800 810 820
pF1KSD YSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQ
790 800 810 820 830 840
pF1KSD ESVLL
:::::
NP_001 ESVLL
>>XP_016872460 (OMIM: 605405) PREDICTED: USP6 N-terminal (846 aa)
initn: 5630 init1: 5630 opt: 5630 Z-score: 3071.6 bits: 579.3 E(85289): 2.4e-164
Smith-Waterman score: 5630; 99.9% identity (100.0% similar) in 827 aa overlap (2-828:20-846)
10 20 30 40
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVY
.::::::::::::::::::::::::::::::::::::::::
XP_016 MCRVWPETKHSRLAEQCEKDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD KVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD LQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRY
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD GVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD FFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD RIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD QISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD RESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSR
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD QYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGP
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD AEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALY
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD PPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNS
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD PKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KSD VDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLP
730 740 750 760 770 780
770 780 790 800 810 820
pF1KSD KYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSI
790 800 810 820 830 840
pF1KSD QESVLL
::::::
XP_016 QESVLL
>>XP_016872462 (OMIM: 605405) PREDICTED: USP6 N-terminal (851 aa)
initn: 5630 init1: 5630 opt: 5630 Z-score: 3071.6 bits: 579.4 E(85289): 2.4e-164
Smith-Waterman score: 5630; 99.9% identity (100.0% similar) in 827 aa overlap (2-828:25-851)
10 20 30
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDA
.:::::::::::::::::::::::::::::::::::
XP_016 MIQVLQIVKELVTPSRQKAATVKEDSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD DYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD YKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD FRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD HAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTP
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD FTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDF
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD VIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD QDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD TVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD RHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPV
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD YHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSR
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD IEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDAS
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD RGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNR
790 800 810 820 830 840
820
pF1KSD DGLSIQESVLL
:::::::::::
XP_016 DGLSIQESVLL
850
>>XP_006717605 (OMIM: 605405) PREDICTED: USP6 N-terminal (856 aa)
initn: 5630 init1: 5630 opt: 5630 Z-score: 3071.5 bits: 579.4 E(85289): 2.4e-164
Smith-Waterman score: 5630; 99.9% identity (100.0% similar) in 827 aa overlap (2-828:30-856)
10 20 30
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIE
.::::::::::::::::::::::::::::::
XP_006 MTTLNPCPQRYVMTAASSSLGPRAKQEEKDSDQDVALKLAQERAEIVAKYDRGREGAEIE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD FHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD RDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD FSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCF
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD LDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFF
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD FEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD GRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRK
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD LPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAH
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD PALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD YSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSY
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD SNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLV
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD LPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSW
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD TRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAY
790 800 810 820 830 840
820
pF1KSD HYRNRDGLSIQESVLL
::::::::::::::::
XP_006 HYRNRDGLSIQESVLL
850
>>XP_011518064 (OMIM: 605405) PREDICTED: USP6 N-terminal (856 aa)
initn: 5630 init1: 5630 opt: 5630 Z-score: 3071.5 bits: 579.4 E(85289): 2.4e-164
Smith-Waterman score: 5630; 99.9% identity (100.0% similar) in 827 aa overlap (2-828:30-856)
10 20 30
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIE
.::::::::::::::::::::::::::::::
XP_011 MTTLNPCPQRYVMTAASSSLGPRAKQEEKDSDQDVALKLAQERAEIVAKYDRGREGAEIE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD FHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD RDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD FSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCF
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD LDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFF
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD FEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD GRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRK
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD LPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAH
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD PALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD YSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSY
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD SNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLV
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD LPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSW
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD TRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAY
790 800 810 820 830 840
820
pF1KSD HYRNRDGLSIQESVLL
::::::::::::::::
XP_011 HYRNRDGLSIQESVLL
850
>>XP_011518065 (OMIM: 605405) PREDICTED: USP6 N-terminal (672 aa)
initn: 4585 init1: 4585 opt: 4585 Z-score: 2506.5 bits: 474.4 E(85289): 7.1e-133
Smith-Waterman score: 4585; 100.0% identity (100.0% similar) in 672 aa overlap (157-828:1-672)
130 140 150 160 170 180
pF1KSD YSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYC
::::::::::::::::::::::::::::::
XP_011 MFRDRYGVKQQSLFHVLAAYSIYNTEVGYC
10 20 30
190 200 210 220 230 240
pF1KSD QGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KSD SKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKL
100 110 120 130 140 150
310 320 330 340 350 360
pF1KSD HKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KSD KKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPE
220 230 240 250 260 270
430 440 450 460 470 480
pF1KSD RAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPK
280 290 300 310 320 330
490 500 510 520 530 540
pF1KSD WNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGS
340 350 360 370 380 390
550 560 570 580 590 600
pF1KSD TASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFK
400 410 420 430 440 450
610 620 630 640 650 660
pF1KSD VQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNP
460 470 480 490 500 510
670 680 690 700 710 720
pF1KSD SRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPP
520 530 540 550 560 570
730 740 750 760 770 780
pF1KSD VDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPV
580 590 600 610 620 630
790 800 810 820
pF1KSD RYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL
::::::::::::::::::::::::::::::::::::::::::
XP_011 RYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL
640 650 660 670
>>XP_016872461 (OMIM: 605405) PREDICTED: USP6 N-terminal (672 aa)
initn: 4585 init1: 4585 opt: 4585 Z-score: 2506.5 bits: 474.4 E(85289): 7.1e-133
Smith-Waterman score: 4585; 100.0% identity (100.0% similar) in 672 aa overlap (157-828:1-672)
130 140 150 160 170 180
pF1KSD YSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYC
::::::::::::::::::::::::::::::
XP_016 MFRDRYGVKQQSLFHVLAAYSIYNTEVGYC
10 20 30
190 200 210 220 230 240
pF1KSD QGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KSD SKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKL
100 110 120 130 140 150
310 320 330 340 350 360
pF1KSD HKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KSD KKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPE
220 230 240 250 260 270
430 440 450 460 470 480
pF1KSD RAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPK
280 290 300 310 320 330
490 500 510 520 530 540
pF1KSD WNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGS
340 350 360 370 380 390
550 560 570 580 590 600
pF1KSD TASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFK
400 410 420 430 440 450
610 620 630 640 650 660
pF1KSD VQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNP
460 470 480 490 500 510
670 680 690 700 710 720
pF1KSD SRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPP
520 530 540 550 560 570
730 740 750 760 770 780
pF1KSD VDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPV
580 590 600 610 620 630
790 800 810 820
pF1KSD RYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL
::::::::::::::::::::::::::::::::::::::::::
XP_016 RYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL
640 650 660 670
>>XP_011522361 (OMIM: 604334) PREDICTED: ubiquitin carbo (786 aa)
initn: 934 init1: 900 opt: 918 Z-score: 517.3 bits: 106.6 E(85289): 4.5e-22
Smith-Waterman score: 926; 36.1% identity (64.3% similar) in 451 aa overlap (12-462:12-447)
10 20 30 40 50 60
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHN
:::: .:. :::.:.... : . . ::::.::: ::: .
XP_011 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMK
. .. . :. ::.::..:: :: ::.. :. :.:::::...:: ::..::.: ..:
XP_011 AREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYN
.. :. .:.:.. : :..::::: :.:.:..::::::.::. ::..: ::: ::
XP_011 LKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEK
:::::. .:.::::.:.:. :::::::::.:... .:.. :: . . .:...:.
XP_011 PEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMS
.. : : : :.. . . .. ... ..: . :.::.::.:. :::.:: ..
XP_011 VVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPIT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPG
::...:.::: : : ... . . ..:: :...:. : .: : . ::: :.
XP_011 SIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQS
:... : : : : . : .: :.. :.: :. .: . :: :
XP_011 KREQGSLAPR----PVPASRGGKTLCKGYRQAP-PGPPAQFQRPICSA------SPPWAS
370 380 390 400
430 440 450 460 470 480
pF1KSD RTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIR
: .:: . :. . .. . . : : .::: : :
XP_011 RFSTPCPGGAVREDTYPVGTQGVPSLALAQ----GGPQGSWRFLEWKSMPRLPTDLDIGG
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD KEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAE
XP_011 PWFPHYDFEWSCWVRAISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTANSSKIDRQKV
470 480 490 500 510 520
>>XP_011522360 (OMIM: 604334) PREDICTED: ubiquitin carbo (1031 aa)
initn: 934 init1: 900 opt: 918 Z-score: 515.6 bits: 106.7 E(85289): 5.5e-22
Smith-Waterman score: 926; 36.1% identity (64.3% similar) in 451 aa overlap (12-462:12-447)
10 20 30 40 50 60
pF1KSD MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHN
:::: .:. :::.:.... : . . ::::.::: ::: .
XP_011 MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMK
. .. . :. ::.::..:: :: ::.. :. :.:::::...:: ::..::.: ..:
XP_011 AREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYN
.. :. .:.:.. : :..::::: :.:.:..::::::.::. ::..: ::: ::
XP_011 LKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEK
:::::. .:.::::.:.:. :::::::::.:... .:.. :: . . .:...:.
XP_011 PEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMS
.. : : : :.. . . .. ... ..: . :.::.::.:. :::.:: ..
XP_011 VVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPIT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPG
::...:.::: : : ... . . ..:: :...:. : .: : . ::: :.
XP_011 SIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQS
:... : : : : . : .: :.. :.: :. .: . :: :
XP_011 KREQGSLAPR----PVPASRGGKTLCKGYRQAP-PGPPAQFQRPICSA------SPPWAS
370 380 390 400
430 440 450 460 470 480
pF1KSD RTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIR
: .:: . :. . .. . . : : .::: : :
XP_011 RFSTPCPGGAVREDTYPVGTQGVPSLALAQ----GGPQGSWRFLEWKSMPRLPTDLDIGG
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD KEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAE
XP_011 PWFPHYDFEWSCWVRAISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTANSSKIDRQKV
470 480 490 500 510 520
828 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:21:26 2016 done: Wed Nov 2 23:21:28 2016
Total Scan time: 12.450 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]