Result of FASTA (omim) for
pF1KSDA0023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0023, 2093 aa
1>>>pF1KSDA0023 2093 - 2093 aa - 2093 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.0276+/-0.000505; mu= -30.8714+/- 0.031
mean_var=716.5798+/-151.098, 0's: 0 Z-trim(121.5): 127 B-trim: 0 in 0/59
Lambda= 0.047912
statistics sampled from 38157 (38299) to 38157 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.449), width: 16
Scan time: 19.780
The best scores are: opt bits E(85289)
XP_006717355 (OMIM: 114350,613065) PREDICTED: nucl (2120) 8046 573.3 9.6e-162
XP_011517355 (OMIM: 114350,613065) PREDICTED: nucl (2120) 8017 571.3 3.9e-161
XP_005272273 (OMIM: 114350,613065) PREDICTED: nucl (2132) 5919 426.3 1.8e-117
NP_005076 (OMIM: 114350,613065) nuclear pore compl (2090) 5917 426.2 1.9e-117
NP_001305253 (OMIM: 114350,613065) nuclear pore co (2080) 5887 424.1 8e-117
XP_016870656 (OMIM: 114350,613065) PREDICTED: nucl (2119) 5878 423.5 1.2e-116
XP_005272276 (OMIM: 114350,613065) PREDICTED: nucl (2036) 5853 421.7 4e-116
NP_001305254 (OMIM: 114350,613065) nuclear pore co ( 916) 5306 383.7 5e-105
XP_005272275 (OMIM: 114350,613065) PREDICTED: nucl (2083) 5189 375.9 2.7e-102
XP_011517357 (OMIM: 114350,613065) PREDICTED: nucl (1908) 4833 351.2 6.3e-95
NP_002448 (OMIM: 158370) mucin-2 precursor [Homo s (5289) 547 55.2 2.2e-05
XP_016868343 (OMIM: 615753) PREDICTED: nuclear env ( 984) 513 52.4 2.9e-05
XP_006716259 (OMIM: 615753) PREDICTED: nuclear env ( 984) 513 52.4 2.9e-05
NP_742017 (OMIM: 615753) nuclear envelope pore mem ( 984) 513 52.4 2.9e-05
XP_016868342 (OMIM: 615753) PREDICTED: nuclear env ( 984) 513 52.4 2.9e-05
XP_005250783 (OMIM: 615753) PREDICTED: nuclear env (1249) 513 52.5 3.5e-05
NP_001244119 (OMIM: 615753) nuclear envelope pore ( 999) 504 51.8 4.5e-05
NP_001291288 (OMIM: 158373) mucin-5AC precursor [H (5654) 526 53.8 6.4e-05
XP_011515032 (OMIM: 615753) PREDICTED: nuclear env (1153) 473 49.7 0.00022
NP_001157934 (OMIM: 604609) mucin-12 precursor [Ho (5335) 489 51.2 0.00036
NP_001014364 (OMIM: 616284) filaggrin-2 [Homo sapi (2391) 474 50.0 0.00038
NP_001035194 (OMIM: 608424) mucin-17 precursor [Ho (4493) 467 49.7 0.0009
XP_005250784 (OMIM: 615753) PREDICTED: nuclear env (1190) 409 45.3 0.0049
NP_060876 (OMIM: 158372) mucin-4 isoform a precurs (5412) 434 47.4 0.0051
NP_005952 (OMIM: 158374) mucin-6 precursor [Homo s (2439) 409 45.5 0.0088
XP_011514552 (OMIM: 158371) PREDICTED: mucin-3A is (3076) 412 45.8 0.0092
XP_016867720 (OMIM: 158371) PREDICTED: mucin-3A is (3143) 412 45.8 0.0093
XP_011514551 (OMIM: 158371) PREDICTED: mucin-3A is (3245) 412 45.8 0.0096
XP_011514549 (OMIM: 158371) PREDICTED: mucin-3A is (3296) 412 45.8 0.0097
XP_011514548 (OMIM: 158371) PREDICTED: mucin-3A is (3313) 412 45.8 0.0098
NP_005951 (OMIM: 158371) mucin-3A precursor [Homo (3323) 412 45.8 0.0098
>>XP_006717355 (OMIM: 114350,613065) PREDICTED: nuclear (2120 aa)
initn: 7624 init1: 7362 opt: 8046 Z-score: 3024.8 bits: 573.3 E(85289): 9.6e-162
Smith-Waterman score: 12917; 98.1% identity (98.5% similar) in 2051 aa overlap (1-2041:42-2091)
10 20 30
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDS
::::::::::::::::::::::::::::::
XP_006 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
260 270 280 290 300 310
280 290 300 310 320 330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
380 390 400 410 420 430
400 410 420 430 440 450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
440 450 460 470 480 490
460 470 480 490 500 510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
500 510 520 530 540 550
520 530 540 550 560 570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
560 570 580 590 600 610
580 590 600 610 620 630
pF1KSD AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
620 630 640 650 660 670
640 650 660 670 680 690
pF1KSD SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
680 690 700 710 720 730
700 710 720 730 740 750
pF1KSD VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
740 750 760 770 780 790
760 770 780 790 800 810
pF1KSD HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
800 810 820 830 840 850
820 830 840 850 860 870
pF1KSD KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
860 870 880 890 900 910
880 890 900 910 920 930
pF1KSD LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
920 930 940 950 960 970
940 950 960 970 980 990
pF1KSD MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
980 990 1000 1010 1020 1030
1000 1010 1020 1030 1040 1050
pF1KSD SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
1040 1050 1060 1070 1080 1090
1060 1070 1080 1090 1100 1110
pF1KSD PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
1100 1110 1120 1130 1140 1150
1120 1130 1140 1150 1160
pF1KSD VVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_006 VVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
1160 1170 1180 1190 1200 1210
1170 1180 1190 1200 1210 1220
pF1KSD GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
1220 1230 1240 1250 1260 1270
1230 1240 1250 1260 1270 1280
pF1KSD ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
1280 1290 1300 1310 1320 1330
1290 1300 1310 1320 1330 1340
pF1KSD ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
1340 1350 1360 1370 1380 1390
1350 1360 1370 1380 1390 1400
pF1KSD PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
1400 1410 1420 1430 1440 1450
1410 1420 1430 1440 1450 1460
pF1KSD SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
1460 1470 1480 1490 1500 1510
1470 1480 1490 1500 1510 1520
pF1KSD TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
1520 1530 1540 1550 1560 1570
1530 1540 1550 1560 1570 1580
pF1KSD VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
1580 1590 1600 1610 1620 1630
1590 1600 1610 1620 1630 1640
pF1KSD SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
1640 1650 1660 1670 1680 1690
1650 1660 1670 1680 1690 1700
pF1KSD NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
1700 1710 1720 1730 1740 1750
1710 1720 1730 1740 1750 1760
pF1KSD GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
1760 1770 1780 1790 1800 1810
1770 1780 1790 1800 1810 1820
pF1KSD SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
1820 1830 1840 1850 1860 1870
1830 1840 1850 1860 1870 1880
pF1KSD FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
1880 1890 1900 1910 1920 1930
1890 1900 1910 1920 1930 1940
pF1KSD PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
1940 1950 1960 1970 1980 1990
1950 1960 1970 1980 1990 2000
pF1KSD SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
2000 2010 2020 2030 2040 2050
2010 2020 2030 2040 2050 2060
pF1KSD GGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKVW
:::: .. : . : : : . . :. : . : .. :
XP_006 GGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNS
2060 2070 2080 2090 2100 2110
2070 2080 2090
pF1KSD EQQQHHILRHARESECPHFRITVPTDFWFWDPE
XP_006 SVQGFGGWRS
2120
>>XP_011517355 (OMIM: 114350,613065) PREDICTED: nuclear (2120 aa)
initn: 7304 init1: 7042 opt: 8017 Z-score: 3013.9 bits: 571.3 E(85289): 3.9e-161
Smith-Waterman score: 12888; 98.0% identity (98.4% similar) in 2052 aa overlap (1-2041:42-2091)
10 20 30
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDS
::::::::::::::::::::::::::::::
XP_011 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
260 270 280 290 300 310
280 290 300 310 320 330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
380 390 400 410 420 430
400 410 420 430 440 450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
440 450 460 470 480 490
460 470 480 490 500 510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
500 510 520 530 540 550
520 530 540 550 560 570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
560 570 580 590 600 610
580 590 600 610 620 630
pF1KSD AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 AMKPSFPPSTSAVKVNLSENS-QSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
620 630 640 650 660 670
640 650 660 670 680
pF1KSD SVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSD
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSD
680 690 700 710 720 730
690 700 710 720 730 740
pF1KSD PVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTES
740 750 760 770 780 790
750 760 770 780 790 800
pF1KSD LHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQY
800 810 820 830 840 850
810 820 830 840 850 860
pF1KSD VKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVD
860 870 880 890 900 910
870 880 890 900 910 920
pF1KSD SLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLS
920 930 940 950 960 970
930 940 950 960 970 980
pF1KSD PMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDAR
980 990 1000 1010 1020 1030
990 1000 1010 1020 1030 1040
pF1KSD TSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKI
1040 1050 1060 1070 1080 1090
1050 1060 1070 1080 1090 1100
pF1KSD IPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVP
1100 1110 1120 1130 1140 1150
1110 1120 1130 1140 1150
pF1KSD QVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPA
:::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 QVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPA
1160 1170 1180 1190 1200 1210
1160 1170 1180 1190 1200 1210
pF1KSD SGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQ
1220 1230 1240 1250 1260 1270
1220 1230 1240 1250 1260 1270
pF1KSD GATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSG
1280 1290 1300 1310 1320 1330
1280 1290 1300 1310 1320 1330
pF1KSD TALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTST
1340 1350 1360 1370 1380 1390
1340 1350 1360 1370 1380 1390
pF1KSD QPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAG
1400 1410 1420 1430 1440 1450
1400 1410 1420 1430 1440 1450
pF1KSD SSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSA
1460 1470 1480 1490 1500 1510
1460 1470 1480 1490 1500 1510
pF1KSD TTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKE
1520 1530 1540 1550 1560 1570
1520 1530 1540 1550 1560 1570
pF1KSD PVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAA
1580 1590 1600 1610 1620 1630
1580 1590 1600 1610 1620 1630
pF1KSD ISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQL
1640 1650 1660 1670 1680 1690
1640 1650 1660 1670 1680 1690
pF1KSD TNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGV
1700 1710 1720 1730 1740 1750
1700 1710 1720 1730 1740 1750
pF1KSD FGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSS
1760 1770 1780 1790 1800 1810
1760 1770 1780 1790 1800 1810
pF1KSD SSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQAS
1820 1830 1840 1850 1860 1870
1820 1830 1840 1850 1860 1870
pF1KSD GFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANK
1880 1890 1900 1910 1920 1930
1880 1890 1900 1910 1920 1930
pF1KSD NPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFG
1940 1950 1960 1970 1980 1990
1940 1950 1960 1970 1980 1990
pF1KSD FSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAAS
2000 2010 2020 2030 2040 2050
2000 2010 2020 2030 2040 2050
pF1KSD AGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKV
::::: .. : . : : : . . :. : . : .. :
XP_011 AGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNN
2060 2070 2080 2090 2100
2060 2070 2080 2090
pF1KSD WEQQQHHILRHARESECPHFRITVPTDFWFWDPE
XP_011 SSVQGFGGWRS
2110 2120
>>XP_005272273 (OMIM: 114350,613065) PREDICTED: nuclear (2132 aa)
initn: 9589 init1: 5595 opt: 5919 Z-score: 2230.2 bits: 426.3 E(85289): 1.8e-117
Smith-Waterman score: 12867; 97.5% identity (98.0% similar) in 2063 aa overlap (1-2041:42-2103)
10 20 30
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDS
::::::::::::::::::::::::::::::
XP_005 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
260 270 280 290 300 310
280 290 300 310 320 330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
380 390 400 410 420 430
400 410 420 430 440 450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
440 450 460 470 480 490
460 470 480 490 500 510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
500 510 520 530 540 550
520 530 540 550 560 570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
560 570 580 590 600 610
580 590 600 610
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
::::::::::::::::::: .:::::::::::::::::::::::::::::
XP_005 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
620 630 640 650 660 670
620 630 640 650 660 670
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
680 690 700 710 720 730
680 690 700 710 720 730
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
740 750 760 770 780 790
740 750 760 770 780 790
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
800 810 820 830 840 850
800 810 820 830 840 850
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
860 870 880 890 900 910
860 870 880 890 900 910
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
920 930 940 950 960 970
920 930 940 950 960 970
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
980 990 1000 1010 1020 1030
980 990 1000 1010 1020 1030
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
1040 1050 1060 1070 1080 1090
1040 1050 1060 1070 1080 1090
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
1100 1110 1120 1130 1140 1150
1100 1110 1120 1130 1140
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_005 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
1160 1170 1180 1190 1200 1210
1150 1160 1170 1180 1190 1200
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
1220 1230 1240 1250 1260 1270
1210 1220 1230 1240 1250 1260
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
1280 1290 1300 1310 1320 1330
1270 1280 1290 1300 1310 1320
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
1340 1350 1360 1370 1380 1390
1330 1340 1350 1360 1370 1380
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
1400 1410 1420 1430 1440 1450
1390 1400 1410 1420 1430 1440
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
1460 1470 1480 1490 1500 1510
1450 1460 1470 1480 1490 1500
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
1520 1530 1540 1550 1560 1570
1510 1520 1530 1540 1550 1560
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
1580 1590 1600 1610 1620 1630
1570 1580 1590 1600 1610 1620
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
1640 1650 1660 1670 1680 1690
1630 1640 1650 1660 1670 1680
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
1700 1710 1720 1730 1740 1750
1690 1700 1710 1720 1730 1740
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
1760 1770 1780 1790 1800 1810
1750 1760 1770 1780 1790 1800
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
1820 1830 1840 1850 1860 1870
1810 1820 1830 1840 1850 1860
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
1880 1890 1900 1910 1920 1930
1870 1880 1890 1900 1910 1920
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
1940 1950 1960 1970 1980 1990
1930 1940 1950 1960 1970 1980
pF1KSD GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
2000 2010 2020 2030 2040 2050
1990 2000 2010 2020 2030 2040
pF1KSD KVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLC
:::::::::::::::: .. : . : : : . . :. : . : .. :
XP_005 KVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGS
2060 2070 2080 2090 2100 2110
2050 2060 2070 2080 2090
pF1KSD MERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
XP_005 GTGGFSFGSNNSSVQGFGGWRS
2120 2130
>>NP_005076 (OMIM: 114350,613065) nuclear pore complex p (2090 aa)
initn: 9592 init1: 5595 opt: 5917 Z-score: 2229.5 bits: 426.2 E(85289): 1.9e-117
Smith-Waterman score: 12879; 97.5% identity (98.0% similar) in 2062 aa overlap (1-2041:1-2061)
10 20 30 40 50 60
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
490 500 510 520 530 540
550 560 570 580
pF1KSD PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSE-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPV
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD NSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVP
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVP
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD SMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEEL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KSD KARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVE
730 740 750 760 770 780
770 780 790 800 810 820
pF1KSD EAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHL
790 800 810 820 830 840
830 840 850 860 870 880
pF1KSD EQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAV
850 860 870 880 890 900
890 900 910 920 930 940
pF1KSD PSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVR
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KSD STAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KSD TPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAP
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KSD SPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTA--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMG
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170
pF1KSD --------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAV
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAV
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KSD TSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGG
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KSD SKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGEL
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KSD LFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVL
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KSD GKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFS
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KSD FGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSA
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KSD LPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSL
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KSD VALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASST
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KSD TSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAAS
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KSD TAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAA
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KSD SVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQ
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KSD SNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGI
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KSD VFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSN
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940 1950
pF1KSD LFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPP
1930 1940 1950 1960 1970 1980
1960 1970 1980 1990 2000 2010
pF1KSD TFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGSLAMSLSPTLKGRLL
::::::::::::::::::::::::::::::::::::::::::::: .. : . : : :
NP_005 TFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFG-FGSSSNTTSFGTLA
1990 2000 2010 2020 2030
2020 2030 2040 2050 2060 2070
pF1KSD LMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKVWEQQQHHILRHARESECPHF
. . :. : . : .. :
NP_005 SQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS
2040 2050 2060 2070 2080 2090
>>NP_001305253 (OMIM: 114350,613065) nuclear pore comple (2080 aa)
initn: 9858 init1: 5595 opt: 5887 Z-score: 2218.4 bits: 424.1 E(85289): 8e-117
Smith-Waterman score: 12905; 98.1% identity (98.5% similar) in 2052 aa overlap (1-2041:1-2051)
10 20 30 40 50 60
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSENSSQSAPPMSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSENSSQSAPPMSP
550 560 570 580 590 600
610 620 630 640 650
pF1KSD FSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRIT
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 FSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRIT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD PPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQ
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD VGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNR
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD DSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD VPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFD
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD SDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRS
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD AFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD HAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQ
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120
pF1KSD AAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTA----------KT
:::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 AAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKT
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KSD PHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQF
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KSD SKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPE
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KSD SSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGET
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KSD LGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTS
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KSD SATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTV
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KSD PPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEV
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KSD SASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPA
1510 1520 1530 1540 1550 1560
1550 1560 1570 1580 1590 1600
pF1KSD TTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSA
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KSD EAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQT
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KSD GSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGF
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KSD SSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSP
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KSD GFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSS
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KSD GSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KSD GGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGG
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KSD VPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGR
::::::::::::::::::::::::::::::::::: .. : . : : : . . :.
NP_001 VPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSL
1990 2000 2010 2020 2030
2030 2040 2050 2060 2070 2080
pF1KSD EQAAPGRKSNESRSLGHLCMERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWF
: . : .. :
NP_001 SQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS
2040 2050 2060 2070 2080
>>XP_016870656 (OMIM: 114350,613065) PREDICTED: nuclear (2119 aa)
initn: 9557 init1: 5595 opt: 5878 Z-score: 2214.9 bits: 423.5 E(85289): 1.2e-116
Smith-Waterman score: 12900; 98.0% identity (98.5% similar) in 2051 aa overlap (1-2041:42-2090)
10 20 30
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDS
::::::::::::::::::::::::::::::
XP_016 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
260 270 280 290 300 310
280 290 300 310 320 330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
380 390 400 410 420 430
400 410 420 430 440 450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
440 450 460 470 480 490
460 470 480 490 500 510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
500 510 520 530 540 550
520 530 540 550 560 570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
560 570 580 590 600 610
580 590 600 610 620 630
pF1KSD AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 AMKPSFPPSTSAVKVNLSENS-QSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
620 630 640 650 660 670
640 650 660 670 680 690
pF1KSD SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
680 690 700 710 720 730
700 710 720 730 740 750
pF1KSD VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
740 750 760 770 780 790
760 770 780 790 800 810
pF1KSD HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
800 810 820 830 840 850
820 830 840 850 860 870
pF1KSD KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
860 870 880 890 900 910
880 890 900 910 920 930
pF1KSD LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
920 930 940 950 960 970
940 950 960 970 980 990
pF1KSD MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
980 990 1000 1010 1020 1030
1000 1010 1020 1030 1040 1050
pF1KSD SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
1040 1050 1060 1070 1080 1090
1060 1070 1080 1090 1100 1110
pF1KSD PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
1100 1110 1120 1130 1140 1150
1120 1130 1140 1150 1160
pF1KSD VVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 VVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
1160 1170 1180 1190 1200 1210
1170 1180 1190 1200 1210 1220
pF1KSD GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
1220 1230 1240 1250 1260 1270
1230 1240 1250 1260 1270 1280
pF1KSD ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
1280 1290 1300 1310 1320 1330
1290 1300 1310 1320 1330 1340
pF1KSD ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
1340 1350 1360 1370 1380 1390
1350 1360 1370 1380 1390 1400
pF1KSD PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
1400 1410 1420 1430 1440 1450
1410 1420 1430 1440 1450 1460
pF1KSD SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
1460 1470 1480 1490 1500 1510
1470 1480 1490 1500 1510 1520
pF1KSD TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
1520 1530 1540 1550 1560 1570
1530 1540 1550 1560 1570 1580
pF1KSD VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
1580 1590 1600 1610 1620 1630
1590 1600 1610 1620 1630 1640
pF1KSD SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
1640 1650 1660 1670 1680 1690
1650 1660 1670 1680 1690 1700
pF1KSD NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
1700 1710 1720 1730 1740 1750
1710 1720 1730 1740 1750 1760
pF1KSD GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
1760 1770 1780 1790 1800 1810
1770 1780 1790 1800 1810 1820
pF1KSD SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
1820 1830 1840 1850 1860 1870
1830 1840 1850 1860 1870 1880
pF1KSD FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
1880 1890 1900 1910 1920 1930
1890 1900 1910 1920 1930 1940
pF1KSD PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
1940 1950 1960 1970 1980 1990
1950 1960 1970 1980 1990 2000
pF1KSD SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
2000 2010 2020 2030 2040 2050
2010 2020 2030 2040 2050 2060
pF1KSD GGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKVW
:::: .. : . : : : . . :. : . : .. :
XP_016 GGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNS
2060 2070 2080 2090 2100
2070 2080 2090
pF1KSD EQQQHHILRHARESECPHFRITVPTDFWFWDPE
XP_016 SVQGFGGWRS
2110
>>XP_005272276 (OMIM: 114350,613065) PREDICTED: nuclear (2036 aa)
initn: 8862 init1: 5595 opt: 5853 Z-score: 2205.8 bits: 421.7 E(85289): 4e-116
Smith-Waterman score: 12043; 92.8% identity (93.3% similar) in 2063 aa overlap (1-2041:42-2007)
10 20 30
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDS
::::::::::::::::::::::::::::::
XP_005 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
260 270 280 290 300 310
280 290 300 310 320 330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
380 390 400 410 420 430
400 410 420 430 440 450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
:::::::::::::::::::::::::::::::::::::::::
XP_005 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSP-------------------
440 450 460 470
460 470 480 490 500 510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
XP_005 ------------------------------------------------------------
520 530 540 550 560 570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
:::::::::::::::::::::::::::::::::::::::::::
XP_005 -----------------ASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
480 490 500 510
580 590 600 610
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
::::::::::::::::::: .:::::::::::::::::::::::::::::
XP_005 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
580 590 600 610 620 630
680 690 700 710 720 730
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
640 650 660 670 680 690
740 750 760 770 780 790
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
700 710 720 730 740 750
800 810 820 830 840 850
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
760 770 780 790 800 810
860 870 880 890 900 910
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
820 830 840 850 860 870
920 930 940 950 960 970
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130 1140
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_005 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KSD GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KSD KVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLC
:::::::::::::::: .. : . : : : . . :. : . : .. :
XP_005 KVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGS
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090
pF1KSD MERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
XP_005 GTGGFSFGSNNSSVQGFGGWRS
2020 2030
>>NP_001305254 (OMIM: 114350,613065) nuclear pore comple (916 aa)
initn: 5364 init1: 5301 opt: 5306 Z-score: 2006.5 bits: 383.7 E(85289): 5e-105
Smith-Waterman score: 5306; 96.7% identity (97.7% similar) in 871 aa overlap (1171-2041:18-887)
1150 1160 1170 1180 1190 1200
pF1KSD QAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGT
::::::::::::::::::::::::::::::
NP_001 MKSSLLLRGVHFCFHLPGTAKIETAVTSTPSASGQFSKPFSFSPSGT
10 20 30 40
1210 1220 1230 1240 1250 1260
pF1KSD GFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSAS
50 60 70 80 90 100
1270 1280 1290 1300 1310 1320
pF1KSD NTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQ
110 120 130 140 150 160
1330 1340 1350 1360 1370 1380
pF1KSD ADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPA
170 180 190 200 210 220
1390 1400 1410 1420 1430 1440
pF1KSD ATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAA
230 240 250 260 270 280
1450 1460 1470 1480 1490 1500
pF1KSD TPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQ
290 300 310 320 330 340
1510 1520 1530 1540 1550 1560
pF1KSD QSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEA
350 360 370 380 390 400
1570 1580 1590 1600 1610 1620
pF1KSD VPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSG
410 420 430 440 450 460
1630 1640 1650 1660 1670 1680
pF1KSD SSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATP
470 480 490 500 510 520
1690 1700 1710 1720 1730 1740
pF1KSD QVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPAS
530 540 550 560 570 580
1750 1760 1770 1780 1790 1800
pF1KSD STPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGG
590 600 610 620 630 640
1810 1820 1830 1840 1850 1860
pF1KSD TSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGR
650 660 670 680 690 700
1870 1880 1890 1900 1910 1920
pF1KSD GGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQ
710 720 730 740 750 760
1930 1940 1950 1960 1970 1980
pF1KSD KPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFT
770 780 790 800 810 820
1990 2000 2010 2020 2030 2040
pF1KSD SPLGSTGGKVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNE
:::::::::::::::::::::::: .. : . : : : . . :. : . : ..
NP_001 SPLGSTGGKVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQS
830 840 850 860 870 880
2050 2060 2070 2080 2090
pF1KSD SRSLGHLCMERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
:
NP_001 SGFSGFGSGTGGFSFGSNNSSVQGFGGWRS
890 900 910
>>XP_005272275 (OMIM: 114350,613065) PREDICTED: nuclear (2083 aa)
initn: 8986 init1: 4992 opt: 5189 Z-score: 1957.6 bits: 375.9 E(85289): 2.7e-102
Smith-Waterman score: 12445; 95.1% identity (95.6% similar) in 2063 aa overlap (1-2041:42-2054)
10 20 30
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDS
::::::::::::::::::::::::::::::
XP_005 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
260 270 280 290 300 310
280 290 300 310 320 330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
380 390 400 410 420 430
400 410 420 430 440 450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
440 450 460 470 480 490
460 470 480 490 500 510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
500 510 520 530 540 550
520 530 540 550 560 570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
560 570 580 590 600 610
580 590 600 610
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
::::::::::::::::::: .:::::::::::::::::::::::::::::
XP_005 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
620 630 640 650 660 670
620 630 640 650 660 670
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
680 690 700 710 720 730
680 690 700 710 720 730
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
740 750 760 770 780 790
740 750 760 770 780 790
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
800 810 820 830 840 850
800 810 820 830 840 850
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
860 870 880 890 900 910
860 870 880 890 900 910
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
920 930 940 950 960 970
920 930 940 950 960 970
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
980 990 1000 1010 1020 1030
980 990 1000 1010 1020 1030
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
1040 1050 1060 1070 1080 1090
1040 1050 1060 1070 1080 1090
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
1100 1110 1120 1130 1140 1150
1100 1110 1120 1130 1140
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_005 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
1160 1170 1180 1190 1200 1210
1150 1160 1170 1180 1190 1200
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
:::::::::::::::::::::::
XP_005 NSLKPSGPTPASGQLSSGDKASG-------------------------------------
1220 1230
1210 1220 1230 1240 1250 1260
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ------------ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
1240 1250 1260 1270 1280
1270 1280 1290 1300 1310 1320
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
1290 1300 1310 1320 1330 1340
1330 1340 1350 1360 1370 1380
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
1350 1360 1370 1380 1390 1400
1390 1400 1410 1420 1430 1440
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
1410 1420 1430 1440 1450 1460
1450 1460 1470 1480 1490 1500
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
1470 1480 1490 1500 1510 1520
1510 1520 1530 1540 1550 1560
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
1530 1540 1550 1560 1570 1580
1570 1580 1590 1600 1610 1620
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
1590 1600 1610 1620 1630 1640
1630 1640 1650 1660 1670 1680
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
1650 1660 1670 1680 1690 1700
1690 1700 1710 1720 1730 1740
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
1710 1720 1730 1740 1750 1760
1750 1760 1770 1780 1790 1800
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
1770 1780 1790 1800 1810 1820
1810 1820 1830 1840 1850 1860
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
1830 1840 1850 1860 1870 1880
1870 1880 1890 1900 1910 1920
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
1890 1900 1910 1920 1930 1940
1930 1940 1950 1960 1970 1980
pF1KSD GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
1950 1960 1970 1980 1990 2000
1990 2000 2010 2020 2030 2040
pF1KSD KVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLC
:::::::::::::::: .. : . : : : . . :. : . : .. :
XP_005 KVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGS
2010 2020 2030 2040 2050 2060
2050 2060 2070 2080 2090
pF1KSD MERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
XP_005 GTGGFSFGSNNSSVQGFGGWRS
2070 2080
>>XP_011517357 (OMIM: 114350,613065) PREDICTED: nuclear (1908 aa)
initn: 8445 init1: 4514 opt: 4833 Z-score: 1825.2 bits: 351.2 E(85289): 6.3e-95
Smith-Waterman score: 11781; 98.8% identity (98.8% similar) in 1865 aa overlap (1-1843:42-1906)
10 20 30
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDS
::::::::::::::::::::::::::::::
XP_011 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
260 270 280 290 300 310
280 290 300 310 320 330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
320 330 340 350 360 370
340 350 360 370 380 390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
380 390 400 410 420 430
400 410 420 430 440 450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
440 450 460 470 480 490
460 470 480 490 500 510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
500 510 520 530 540 550
520 530 540 550 560 570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
560 570 580 590 600 610
580 590 600 610
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
::::::::::::::::::: .:::::::::::::::::::::::::::::
XP_011 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
620 630 640 650 660 670
620 630 640 650 660 670
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
680 690 700 710 720 730
680 690 700 710 720 730
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
740 750 760 770 780 790
740 750 760 770 780 790
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
800 810 820 830 840 850
800 810 820 830 840 850
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
860 870 880 890 900 910
860 870 880 890 900 910
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
920 930 940 950 960 970
920 930 940 950 960 970
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
980 990 1000 1010 1020 1030
980 990 1000 1010 1020 1030
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
1040 1050 1060 1070 1080 1090
1040 1050 1060 1070 1080 1090
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
1100 1110 1120 1130 1140 1150
1100 1110 1120 1130 1140
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
1160 1170 1180 1190 1200 1210
1150 1160 1170 1180 1190 1200
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
1220 1230 1240 1250 1260 1270
1210 1220 1230 1240 1250 1260
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
1280 1290 1300 1310 1320 1330
1270 1280 1290 1300 1310 1320
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
1340 1350 1360 1370 1380 1390
1330 1340 1350 1360 1370 1380
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
1400 1410 1420 1430 1440 1450
1390 1400 1410 1420 1430 1440
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
1460 1470 1480 1490 1500 1510
1450 1460 1470 1480 1490 1500
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
1520 1530 1540 1550 1560 1570
1510 1520 1530 1540 1550 1560
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
1580 1590 1600 1610 1620 1630
1570 1580 1590 1600 1610 1620
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
1640 1650 1660 1670 1680 1690
1630 1640 1650 1660 1670 1680
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
1700 1710 1720 1730 1740 1750
1690 1700 1710 1720 1730 1740
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
1760 1770 1780 1790 1800 1810
1750 1760 1770 1780 1790 1800
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
1820 1830 1840 1850 1860 1870
1810 1820 1830 1840 1850 1860
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
:::::::::::::::::::::::::::::::::::
XP_011 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQYL
1880 1890 1900
1870 1880 1890 1900 1910 1920
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
2093 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:24:28 2016 done: Wed Nov 2 23:24:31 2016
Total Scan time: 19.780 Total Display time: 1.500
Function used was FASTA [36.3.4 Apr, 2011]