FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0025, 391 aa
  1>>>pF1KSDA0025 391 - 391 aa - 391 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9461+/-0.000297; mu= 10.6432+/- 0.019
 mean_var=132.5403+/-26.901, 0's: 0 Z-trim(121.1): 21  B-trim: 0 in 0/59
 Lambda= 0.111404
 statistics sampled from 37254 (37275) to 37254 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.437), width:  16
 Scan time:  8.150

The best scores are:                                      opt bits E(85289)
NP_055500 (OMIM: 608070) homocysteine-responsive e ( 391) 2718 447.7 2.2e-125
NP_001010989 (OMIM: 608070) homocysteine-responsiv ( 390) 2699 444.7 1.8e-124
NP_001259032 (OMIM: 608070) homocysteine-responsiv ( 275) 1718 286.9   4e-77


>>NP_055500 (OMIM: 608070) homocysteine-responsive endop  (391 aa)
 initn: 2718 init1: 2718 opt: 2718  Z-score: 2372.1  bits: 447.7 E(85289): 2.2e-125
Smith-Waterman score: 2718; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391)

               10        20        30        40        50        60
pF1KSD MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD YYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGE
              310       320       330       340       350       360

              370       380       390 
pF1KSD QTSPSFMSTAWLVFKTFFASLLPEGPPAIAN
       :::::::::::::::::::::::::::::::
NP_055 QTSPSFMSTAWLVFKTFFASLLPEGPPAIAN
              370       380       390 

>>NP_001010989 (OMIM: 608070) homocysteine-responsive en  (390 aa)
 initn: 2195 init1: 2195 opt: 2699  Z-score: 2355.6  bits: 444.7 E(85289): 1.8e-124
Smith-Waterman score: 2699; 99.7% identity (99.7% similar) in 391 aa overlap (1-391:1-390)

               10        20        30        40        50        60
pF1KSD MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDS
       ::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLLDHQCLRDLLPK-EKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDS
               70         80        90       100       110         

              130       140       150       160       170       180
pF1KSD SSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQ
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KSD YYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGA
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KSD NQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVM
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KSD YLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGE
     300       310       320       330       340       350         

              370       380       390 
pF1KSD QTSPSFMSTAWLVFKTFFASLLPEGPPAIAN
       :::::::::::::::::::::::::::::::
NP_001 QTSPSFMSTAWLVFKTFFASLLPEGPPAIAN
     360       370       380       390

>>NP_001259032 (OMIM: 608070) homocysteine-responsive en  (275 aa)
 initn: 1718 init1: 1718 opt: 1718  Z-score: 1505.6  bits: 286.9 E(85289): 4e-77
Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 250 aa overlap (1-250:1-250)

               10        20        30        40        50        60
pF1KSD MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD YYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVM
       ::::::::::                                                  
NP_001 NQNLRMNAQGITLGGFHLDRGRFRTSQMMVLLLTL                         
              250       260       270                              




391 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:26:20 2016 done: Wed Nov  2 23:26:21 2016
 Total Scan time:  8.150 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]