FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0027, 377 aa 1>>>pF1KSDA0027 377 - 377 aa - 377 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2055+/-0.000373; mu= 17.2443+/- 0.023 mean_var=64.8349+/-12.754, 0's: 0 Z-trim(112.4): 16 B-trim: 0 in 0/52 Lambda= 0.159283 statistics sampled from 21287 (21298) to 21287 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.25), width: 16 Scan time: 7.410 The best scores are: opt bits E(85289) XP_016884160 (OMIM: 604004,605908) PREDICTED: memb ( 377) 2454 572.8 4.5e-163 NP_055981 (OMIM: 604004,605908) membrane protein M ( 377) 2454 572.8 4.5e-163 NP_631941 (OMIM: 604004,605908) membrane protein M ( 377) 2454 572.8 4.5e-163 XP_011528980 (OMIM: 604004,605908) PREDICTED: memb ( 322) 1945 455.8 6.4e-128 >>XP_016884160 (OMIM: 604004,605908) PREDICTED: membrane (377 aa) initn: 2454 init1: 2454 opt: 2454 Z-score: 3048.7 bits: 572.8 E(85289): 4.5e-163 Smith-Waterman score: 2454; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KSD MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD YDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLK 310 320 330 340 350 360 370 pF1KSD EFDKEKAWRAVVVQMAQ ::::::::::::::::: XP_016 EFDKEKAWRAVVVQMAQ 370 >>NP_055981 (OMIM: 604004,605908) membrane protein MLC1 (377 aa) initn: 2454 init1: 2454 opt: 2454 Z-score: 3048.7 bits: 572.8 E(85289): 4.5e-163 Smith-Waterman score: 2454; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KSD MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD YDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLK 310 320 330 340 350 360 370 pF1KSD EFDKEKAWRAVVVQMAQ ::::::::::::::::: NP_055 EFDKEKAWRAVVVQMAQ 370 >>NP_631941 (OMIM: 604004,605908) membrane protein MLC1 (377 aa) initn: 2454 init1: 2454 opt: 2454 Z-score: 3048.7 bits: 572.8 E(85289): 4.5e-163 Smith-Waterman score: 2454; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377) 10 20 30 40 50 60 pF1KSD MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD YDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 YDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLK 310 320 330 340 350 360 370 pF1KSD EFDKEKAWRAVVVQMAQ ::::::::::::::::: NP_631 EFDKEKAWRAVVVQMAQ 370 >>XP_011528980 (OMIM: 604004,605908) PREDICTED: membrane (322 aa) initn: 1945 init1: 1945 opt: 1945 Z-score: 2417.6 bits: 455.8 E(85289): 6.4e-128 Smith-Waterman score: 1981; 85.4% identity (85.4% similar) in 377 aa overlap (1-377:1-322) 10 20 30 40 50 60 pF1KSD MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIK-- 250 260 270 280 290 310 320 330 340 350 360 pF1KSD YDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLK ::::::: XP_011 -----------------------------------------------------VARSPLK 300 370 pF1KSD EFDKEKAWRAVVVQMAQ ::::::::::::::::: XP_011 EFDKEKAWRAVVVQMAQ 310 320 377 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:27:33 2016 done: Wed Nov 2 23:27:34 2016 Total Scan time: 7.410 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]