FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0032, 1050 aa 1>>>pF1KSDA0032 1050 - 1050 aa - 1050 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3237+/-0.000517; mu= 21.7512+/- 0.032 mean_var=75.5594+/-15.756, 0's: 0 Z-trim(108.2): 347 B-trim: 393 in 1/50 Lambda= 0.147547 statistics sampled from 15954 (16311) to 15954 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.532), E-opt: 0.2 (0.191), width: 16 Scan time: 11.930 The best scores are: opt bits E(85289) NP_055421 (OMIM: 605200) probable E3 ubiquitin-pro (1050) 7061 1513.8 0 XP_005263384 (OMIM: 605200) PREDICTED: probable E3 (1050) 7061 1513.8 0 XP_016864295 (OMIM: 605200) PREDICTED: probable E3 (1042) 6985 1497.6 0 XP_005263386 (OMIM: 605200) PREDICTED: probable E3 (1042) 6985 1497.6 0 NP_001258531 (OMIM: 605200) probable E3 ubiquitin- ( 932) 6231 1337.1 0 XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ( 924) 6155 1320.9 0 XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ( 903) 5982 1284.1 0 XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ( 896) 5976 1282.8 0 XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ( 993) 4601 990.2 0 NP_071362 (OMIM: 609248) probable E3 ubiquitin-pro (1057) 3972 856.3 0 NP_056416 (OMIM: 609248) probable E3 ubiquitin-pro (1049) 3969 855.6 0 XP_016864297 (OMIM: 605200) PREDICTED: probable E3 ( 580) 3837 827.4 0 XP_011537898 (OMIM: 609248) PREDICTED: probable E3 ( 987) 3705 799.4 0 XP_011537897 (OMIM: 609248) PREDICTED: probable E3 (1011) 3499 755.6 3.2e-217 XP_011537896 (OMIM: 609248) PREDICTED: probable E3 (1011) 3499 755.6 3.2e-217 XP_011537894 (OMIM: 609248) PREDICTED: probable E3 (1081) 3497 755.2 4.5e-217 XP_011537895 (OMIM: 609248) PREDICTED: probable E3 (1073) 3483 752.2 3.5e-216 XP_011530699 (OMIM: 605200) PREDICTED: probable E3 ( 494) 3256 703.6 6.8e-202 NP_001265115 (OMIM: 609248) probable E3 ubiquitin- ( 794) 2947 638.0 6.2e-182 NP_001265114 (OMIM: 609248) probable E3 ubiquitin- ( 979) 2729 591.7 6.8e-168 NP_001305434 (OMIM: 605200) probable E3 ubiquitin- ( 368) 2466 535.4 2.3e-151 XP_011537899 (OMIM: 609248) PREDICTED: probable E3 ( 960) 1893 413.7 2.5e-114 XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ( 936) 1727 378.4 1.1e-103 XP_016863822 (OMIM: 609249) PREDICTED: probable E3 ( 614) 1282 283.5 2.5e-75 NP_001158608 (OMIM: 609249) probable E3 ubiquitin- ( 986) 1024 228.7 1.2e-58 NP_060382 (OMIM: 609249) probable E3 ubiquitin-pro (1022) 1024 228.7 1.3e-58 XP_016878044 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_016878041 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_016878043 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_006720739 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_005268324 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 NP_570853 (OMIM: 105830,601623) ubiquitin-protein ( 852) 960 215.1 1.4e-54 XP_005268328 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_006720738 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_016878040 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_016878042 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_005268326 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_005268325 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 XP_005268327 (OMIM: 105830,601623) PREDICTED: ubiq ( 852) 960 215.1 1.4e-54 NP_570854 (OMIM: 105830,601623) ubiquitin-protein ( 872) 960 215.1 1.4e-54 XP_016878038 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 960 215.1 1.4e-54 XP_016878037 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 960 215.1 1.4e-54 XP_016878036 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 960 215.1 1.4e-54 XP_016878039 (OMIM: 105830,601623) PREDICTED: ubiq ( 872) 960 215.1 1.4e-54 XP_016878034 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 960 215.1 1.4e-54 NP_000453 (OMIM: 105830,601623) ubiquitin-protein ( 875) 960 215.1 1.4e-54 XP_016878035 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 960 215.1 1.4e-54 XP_016878033 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 960 215.1 1.4e-54 XP_011520297 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 960 215.1 1.4e-54 XP_011520296 (OMIM: 105830,601623) PREDICTED: ubiq ( 875) 960 215.1 1.4e-54 >>NP_055421 (OMIM: 605200) probable E3 ubiquitin-protein (1050 aa) initn: 7061 init1: 7061 opt: 7061 Z-score: 8118.4 bits: 1513.8 E(85289): 0 Smith-Waterman score: 7061; 100.0% identity (100.0% similar) in 1050 aa overlap (1-1050:1-1050) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN 970 980 990 1000 1010 1020 1030 1040 1050 pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA :::::::::::::::::::::::::::::: NP_055 LLDLPKYSSKEILSARLTQALDNYEGFSLA 1030 1040 1050 >>XP_005263384 (OMIM: 605200) PREDICTED: probable E3 ubi (1050 aa) initn: 7061 init1: 7061 opt: 7061 Z-score: 8118.4 bits: 1513.8 E(85289): 0 Smith-Waterman score: 7061; 100.0% identity (100.0% similar) in 1050 aa overlap (1-1050:1-1050) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN 970 980 990 1000 1010 1020 1030 1040 1050 pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA :::::::::::::::::::::::::::::: XP_005 LLDLPKYSSKEILSARLTQALDNYEGFSLA 1030 1040 1050 >>XP_016864295 (OMIM: 605200) PREDICTED: probable E3 ubi (1042 aa) initn: 6997 init1: 4327 opt: 6985 Z-score: 8031.0 bits: 1497.6 E(85289): 0 Smith-Waterman score: 6985; 99.2% identity (99.2% similar) in 1050 aa overlap (1-1050:1-1042) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ ::::::::::::::::::::::::::::::::::::: ::::::::::::::: XP_016 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGM--------DTVTLCSYPFIFDAQ 610 620 630 640 650 670 680 690 700 710 720 pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN 960 970 980 990 1000 1010 1030 1040 1050 pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA :::::::::::::::::::::::::::::: XP_016 LLDLPKYSSKEILSARLTQALDNYEGFSLA 1020 1030 1040 >>XP_005263386 (OMIM: 605200) PREDICTED: probable E3 ubi (1042 aa) initn: 6997 init1: 4327 opt: 6985 Z-score: 8031.0 bits: 1497.6 E(85289): 0 Smith-Waterman score: 6985; 99.2% identity (99.2% similar) in 1050 aa overlap (1-1050:1-1042) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ ::::::::::::::::::::::::::::::::::::: ::::::::::::::: XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGM--------DTVTLCSYPFIFDAQ 610 620 630 640 650 670 680 690 700 710 720 pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN 960 970 980 990 1000 1010 1030 1040 1050 pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA :::::::::::::::::::::::::::::: XP_005 LLDLPKYSSKEILSARLTQALDNYEGFSLA 1020 1030 1040 >>NP_001258531 (OMIM: 605200) probable E3 ubiquitin-prot (932 aa) initn: 6231 init1: 6231 opt: 6231 Z-score: 7164.3 bits: 1337.1 E(85289): 0 Smith-Waterman score: 6231; 100.0% identity (100.0% similar) in 932 aa overlap (119-1050:1-932) 90 100 110 120 130 140 pF1KSD VACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWH :::::::::::::::::::::::::::::: NP_001 MTTEDSVAVPRLIQKLNQQTILQVSCGNWH 10 20 30 150 160 170 180 190 200 pF1KSD CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS 40 50 60 70 80 90 210 220 230 240 250 260 pF1KSD GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA 100 110 120 130 140 150 270 280 290 300 310 320 pF1KSD GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG 160 170 180 190 200 210 330 340 350 360 370 380 pF1KSD TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV 220 230 240 250 260 270 390 400 410 420 430 440 pF1KSD DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH 280 290 300 310 320 330 450 460 470 480 490 500 pF1KSD FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL 340 350 360 370 380 390 510 520 530 540 550 560 pF1KSD ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL 400 410 420 430 440 450 570 580 590 600 610 620 pF1KSD YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL 460 470 480 490 500 510 630 640 650 660 670 680 pF1KSD MWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM 520 530 540 550 560 570 690 700 710 720 730 740 pF1KSD LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK 580 590 600 610 620 630 750 760 770 780 790 800 pF1KSD EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH 640 650 660 670 680 690 810 820 830 840 850 860 pF1KSD FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE 700 710 720 730 740 750 870 880 890 900 910 920 pF1KSD QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS 760 770 780 790 800 810 930 940 950 960 970 980 pF1KSD ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD 820 830 840 850 860 870 990 1000 1010 1020 1030 1040 pF1KSD RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS 880 890 900 910 920 930 1050 pF1KSD LA :: NP_001 LA >>XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ubi (924 aa) initn: 6167 init1: 3497 opt: 6155 Z-score: 7076.9 bits: 1320.9 E(85289): 0 Smith-Waterman score: 6155; 99.1% identity (99.1% similar) in 932 aa overlap (119-1050:1-924) 90 100 110 120 130 140 pF1KSD VACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWH :::::::::::::::::::::::::::::: XP_016 MTTEDSVAVPRLIQKLNQQTILQVSCGNWH 10 20 30 150 160 170 180 190 200 pF1KSD CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS 40 50 60 70 80 90 210 220 230 240 250 260 pF1KSD GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA 100 110 120 130 140 150 270 280 290 300 310 320 pF1KSD GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG 160 170 180 190 200 210 330 340 350 360 370 380 pF1KSD TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV 220 230 240 250 260 270 390 400 410 420 430 440 pF1KSD DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH 280 290 300 310 320 330 450 460 470 480 490 500 pF1KSD FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL 340 350 360 370 380 390 510 520 530 540 550 560 pF1KSD ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL 400 410 420 430 440 450 570 580 590 600 610 620 pF1KSD YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL 460 470 480 490 500 510 630 640 650 660 670 680 pF1KSD MWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM ::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_016 MWFLHQAGM--------DTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM 520 530 540 550 560 690 700 710 720 730 740 pF1KSD LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK 570 580 590 600 610 620 750 760 770 780 790 800 pF1KSD EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH 630 640 650 660 670 680 810 820 830 840 850 860 pF1KSD FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE 690 700 710 720 730 740 870 880 890 900 910 920 pF1KSD QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS 750 760 770 780 790 800 930 940 950 960 970 980 pF1KSD ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD 810 820 830 840 850 860 990 1000 1010 1020 1030 1040 pF1KSD RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS 870 880 890 900 910 920 1050 pF1KSD LA :: XP_016 LA >>XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ubi (903 aa) initn: 6393 init1: 5979 opt: 5982 Z-score: 6878.0 bits: 1284.1 E(85289): 0 Smith-Waterman score: 5982; 98.4% identity (99.3% similar) in 903 aa overlap (1-901:1-902) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE 790 800 810 820 830 840 850 860 870 880 890 pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQ--EFVDAYVNYVF ::::::::::::::::::::::::::::::::::::::::::::::. .: : .. . : XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRKKNDFED-FAVFRF 850 860 870 880 890 900 910 920 930 940 950 pF1KSD QISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSAT ... XP_005 RLTR 900 >>XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ubi (896 aa) initn: 5976 init1: 5976 opt: 5976 Z-score: 6871.1 bits: 1282.8 E(85289): 0 Smith-Waterman score: 5976; 100.0% identity (100.0% similar) in 886 aa overlap (1-886:1-886) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI :::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRLSKKPQLWGK 850 860 870 880 890 910 920 930 940 950 960 pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP >>XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ubi (993 aa) initn: 4586 init1: 4586 opt: 4601 Z-score: 5288.7 bits: 990.2 E(85289): 0 Smith-Waterman score: 6579; 94.6% identity (94.6% similar) in 1050 aa overlap (1-1050:1-993) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS :::::::::::::::: XP_005 AKTKMLQTDAELQMQV-------------------------------------------- 670 730 740 750 760 770 780 pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT ::::::::::::::::::::::::::::::::::::::::::::::: XP_005 -------------IFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT 680 690 700 710 720 790 800 810 820 830 840 pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE 730 740 750 760 770 780 850 860 870 880 890 900 pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI 790 800 810 820 830 840 910 920 930 940 950 960 pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP 850 860 870 880 890 900 970 980 990 1000 1010 1020 pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN 910 920 930 940 950 960 1030 1040 1050 pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA :::::::::::::::::::::::::::::: XP_005 LLDLPKYSSKEILSARLTQALDNYEGFSLA 970 980 990 >>NP_071362 (OMIM: 609248) probable E3 ubiquitin-protein (1057 aa) initn: 3818 init1: 2042 opt: 3972 Z-score: 4564.7 bits: 856.3 E(85289): 0 Smith-Waterman score: 3972; 56.0% identity (78.7% similar) in 1057 aa overlap (1-1049:1-1056) 10 20 30 40 50 60 pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL ::::: :.:: :.. . :: ::. :. .. :..:.:: :.::.:.:: ::::: NP_071 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT : ::::::. .::::. :: :.:. :.:::.:.:::.:.::...:: :::::::. NP_071 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS .:. . ::: :..:.. :.::.:: .: :::. .. : ::.:..:::::: . .:.: NP_071 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR :: ..:: :::. ::::::::::.:.::::.:::: :. :::::.::.:: : .: :: NP_071 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA .::.::: :::.:::.::: :::::::::. :::::.: . :.:::.:.::::: ::.:: NP_071 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK :::::: ::::::: ::.:: :. :::::: : : : : ::: : ..:: : . NP_071 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA : ::.:::::::.: :. .: .: ::: : .. .:. : : . : . . NP_071 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE . : . .::..: ::::: . :.:..:. .. :.:.:..:.::.::.. .: .: . NP_071 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP :. :.:. :::.:.:: :::::.:.:: ::: ::..::. . :..::.. :.. :. : NP_071 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP 490 500 510 520 530 540 550 560 570 580 590 pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPV---LFNNYITAALKLLEKL :::.:::: . : :.:.:.:.: .:..::. : . : .::... .:::.:: : NP_071 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD YKVNLKVKHV-EYDTFYIPEISNLVDIQEDYLMWFLHQA-GMKARPSIIQ--DT-VTLCS ..:: :. .. .:: ::: :...:.::..::. : .:: :: . .. . : ::.:. NP_071 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD YPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLV :::.::::::: .::::: ::::.:.. :. ::: :. : . . .: :.: :::.:.: NP_071 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF-LPVIESVNPCLILVVRRENIV 670 680 690 700 710 720 730 740 750 760 770 pF1KSD GDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDS :::.. : ..:: :::::::: ::.::::::: ::::::...:::.: :::: ::.:: NP_071 GDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS 720 730 740 750 760 770 780 790 800 810 820 830 pF1KSD NLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSP :.:::: : . . :::::. ::::::: :.::::::::::::::. ::.:.::::: : NP_071 RLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMP 780 790 800 810 820 830 840 850 860 870 880 890 pF1KSD TEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDA :::.:.::::: .:.:::::::::: :..:. : :.:. .: ...: :.:::::::: NP_071 DVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDA 840 850 860 870 880 890 900 910 920 930 940 950 pF1KSD YVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYK ::.:.:. :: . :: .:: :::::::: ::::.::.::..::.::.:.:::... :: NP_071 YVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYK 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KSD GDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYL :.: : :::.:.:::.:::.::::::.::::::::::::: :: ::..:::::..::::: NP_071 GEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYL 960 970 980 990 1000 1010 1020 1030 1040 1050 pF1KSD PVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSLA ::.:::.::::::::. :: : ..: ::.:. ::::: NP_071 PVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI 1020 1030 1040 1050 1050 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:30:10 2016 done: Wed Nov 2 23:30:12 2016 Total Scan time: 11.930 Total Display time: 0.480 Function used was FASTA [36.3.4 Apr, 2011]