Result of FASTA (omim) for pF1KSDA0032
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0032, 1050 aa
  1>>>pF1KSDA0032 1050 - 1050 aa - 1050 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3237+/-0.000517; mu= 21.7512+/- 0.032
 mean_var=75.5594+/-15.756, 0's: 0 Z-trim(108.2): 347  B-trim: 393 in 1/50
 Lambda= 0.147547
 statistics sampled from 15954 (16311) to 15954 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.532), E-opt: 0.2 (0.191), width:  16
 Scan time: 11.930

The best scores are:                                      opt bits E(85289)
NP_055421 (OMIM: 605200) probable E3 ubiquitin-pro (1050) 7061 1513.8       0
XP_005263384 (OMIM: 605200) PREDICTED: probable E3 (1050) 7061 1513.8       0
XP_016864295 (OMIM: 605200) PREDICTED: probable E3 (1042) 6985 1497.6       0
XP_005263386 (OMIM: 605200) PREDICTED: probable E3 (1042) 6985 1497.6       0
NP_001258531 (OMIM: 605200) probable E3 ubiquitin- ( 932) 6231 1337.1       0
XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ( 924) 6155 1320.9       0
XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ( 903) 5982 1284.1       0
XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ( 896) 5976 1282.8       0
XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ( 993) 4601 990.2       0
NP_071362 (OMIM: 609248) probable E3 ubiquitin-pro (1057) 3972 856.3       0
NP_056416 (OMIM: 609248) probable E3 ubiquitin-pro (1049) 3969 855.6       0
XP_016864297 (OMIM: 605200) PREDICTED: probable E3 ( 580) 3837 827.4       0
XP_011537898 (OMIM: 609248) PREDICTED: probable E3 ( 987) 3705 799.4       0
XP_011537897 (OMIM: 609248) PREDICTED: probable E3 (1011) 3499 755.6 3.2e-217
XP_011537896 (OMIM: 609248) PREDICTED: probable E3 (1011) 3499 755.6 3.2e-217
XP_011537894 (OMIM: 609248) PREDICTED: probable E3 (1081) 3497 755.2 4.5e-217
XP_011537895 (OMIM: 609248) PREDICTED: probable E3 (1073) 3483 752.2 3.5e-216
XP_011530699 (OMIM: 605200) PREDICTED: probable E3 ( 494) 3256 703.6 6.8e-202
NP_001265115 (OMIM: 609248) probable E3 ubiquitin- ( 794) 2947 638.0 6.2e-182
NP_001265114 (OMIM: 609248) probable E3 ubiquitin- ( 979) 2729 591.7 6.8e-168
NP_001305434 (OMIM: 605200) probable E3 ubiquitin- ( 368) 2466 535.4 2.3e-151
XP_011537899 (OMIM: 609248) PREDICTED: probable E3 ( 960) 1893 413.7 2.5e-114
XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ( 936) 1727 378.4 1.1e-103
XP_016863822 (OMIM: 609249) PREDICTED: probable E3 ( 614) 1282 283.5 2.5e-75
NP_001158608 (OMIM: 609249) probable E3 ubiquitin- ( 986) 1024 228.7 1.2e-58
NP_060382 (OMIM: 609249) probable E3 ubiquitin-pro (1022) 1024 228.7 1.3e-58
XP_016878044 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_016878041 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_016878043 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_006720739 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_005268324 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
NP_570853 (OMIM: 105830,601623) ubiquitin-protein  ( 852)  960 215.1 1.4e-54
XP_005268328 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_006720738 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_016878040 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_016878042 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_005268326 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_005268325 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
XP_005268327 (OMIM: 105830,601623) PREDICTED: ubiq ( 852)  960 215.1 1.4e-54
NP_570854 (OMIM: 105830,601623) ubiquitin-protein  ( 872)  960 215.1 1.4e-54
XP_016878038 (OMIM: 105830,601623) PREDICTED: ubiq ( 872)  960 215.1 1.4e-54
XP_016878037 (OMIM: 105830,601623) PREDICTED: ubiq ( 872)  960 215.1 1.4e-54
XP_016878036 (OMIM: 105830,601623) PREDICTED: ubiq ( 872)  960 215.1 1.4e-54
XP_016878039 (OMIM: 105830,601623) PREDICTED: ubiq ( 872)  960 215.1 1.4e-54
XP_016878034 (OMIM: 105830,601623) PREDICTED: ubiq ( 875)  960 215.1 1.4e-54
NP_000453 (OMIM: 105830,601623) ubiquitin-protein  ( 875)  960 215.1 1.4e-54
XP_016878035 (OMIM: 105830,601623) PREDICTED: ubiq ( 875)  960 215.1 1.4e-54
XP_016878033 (OMIM: 105830,601623) PREDICTED: ubiq ( 875)  960 215.1 1.4e-54
XP_011520297 (OMIM: 105830,601623) PREDICTED: ubiq ( 875)  960 215.1 1.4e-54
XP_011520296 (OMIM: 105830,601623) PREDICTED: ubiq ( 875)  960 215.1 1.4e-54


>>NP_055421 (OMIM: 605200) probable E3 ubiquitin-protein  (1050 aa)
 initn: 7061 init1: 7061 opt: 7061  Z-score: 8118.4  bits: 1513.8 E(85289):    0
Smith-Waterman score: 7061; 100.0% identity (100.0% similar) in 1050 aa overlap (1-1050:1-1050)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
              970       980       990      1000      1010      1020

             1030      1040      1050
pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA
       ::::::::::::::::::::::::::::::
NP_055 LLDLPKYSSKEILSARLTQALDNYEGFSLA
             1030      1040      1050

>>XP_005263384 (OMIM: 605200) PREDICTED: probable E3 ubi  (1050 aa)
 initn: 7061 init1: 7061 opt: 7061  Z-score: 8118.4  bits: 1513.8 E(85289):    0
Smith-Waterman score: 7061; 100.0% identity (100.0% similar) in 1050 aa overlap (1-1050:1-1050)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
              970       980       990      1000      1010      1020

             1030      1040      1050
pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA
       ::::::::::::::::::::::::::::::
XP_005 LLDLPKYSSKEILSARLTQALDNYEGFSLA
             1030      1040      1050

>>XP_016864295 (OMIM: 605200) PREDICTED: probable E3 ubi  (1042 aa)
 initn: 6997 init1: 4327 opt: 6985  Z-score: 8031.0  bits: 1497.6 E(85289):    0
Smith-Waterman score: 6985; 99.2% identity (99.2% similar) in 1050 aa overlap (1-1050:1-1042)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
       :::::::::::::::::::::::::::::::::::::        :::::::::::::::
XP_016 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGM--------DTVTLCSYPFIFDAQ
              610       620       630               640       650  

              670       680       690       700       710       720
pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
            660       670       680       690       700       710  

              730       740       750       760       770       780
pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
            720       730       740       750       760       770  

              790       800       810       820       830       840
pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
            780       790       800       810       820       830  

              850       860       870       880       890       900
pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
            840       850       860       870       880       890  

              910       920       930       940       950       960
pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
            900       910       920       930       940       950  

              970       980       990      1000      1010      1020
pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
            960       970       980       990      1000      1010  

             1030      1040      1050
pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA
       ::::::::::::::::::::::::::::::
XP_016 LLDLPKYSSKEILSARLTQALDNYEGFSLA
           1020      1030      1040  

>>XP_005263386 (OMIM: 605200) PREDICTED: probable E3 ubi  (1042 aa)
 initn: 6997 init1: 4327 opt: 6985  Z-score: 8031.0  bits: 1497.6 E(85289):    0
Smith-Waterman score: 6985; 99.2% identity (99.2% similar) in 1050 aa overlap (1-1050:1-1042)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
       :::::::::::::::::::::::::::::::::::::        :::::::::::::::
XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGM--------DTVTLCSYPFIFDAQ
              610       620       630               640       650  

              670       680       690       700       710       720
pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
            660       670       680       690       700       710  

              730       740       750       760       770       780
pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
            720       730       740       750       760       770  

              790       800       810       820       830       840
pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
            780       790       800       810       820       830  

              850       860       870       880       890       900
pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
            840       850       860       870       880       890  

              910       920       930       940       950       960
pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
            900       910       920       930       940       950  

              970       980       990      1000      1010      1020
pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
            960       970       980       990      1000      1010  

             1030      1040      1050
pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA
       ::::::::::::::::::::::::::::::
XP_005 LLDLPKYSSKEILSARLTQALDNYEGFSLA
           1020      1030      1040  

>>NP_001258531 (OMIM: 605200) probable E3 ubiquitin-prot  (932 aa)
 initn: 6231 init1: 6231 opt: 6231  Z-score: 7164.3  bits: 1337.1 E(85289):    0
Smith-Waterman score: 6231; 100.0% identity (100.0% similar) in 932 aa overlap (119-1050:1-932)

       90       100       110       120       130       140        
pF1KSD VACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWH
                                     ::::::::::::::::::::::::::::::
NP_001                               MTTEDSVAVPRLIQKLNQQTILQVSCGNWH
                                             10        20        30

      150       160       170       180       190       200        
pF1KSD CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS
               40        50        60        70        80        90

      210       220       230       240       250       260        
pF1KSD GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA
              100       110       120       130       140       150

      270       280       290       300       310       320        
pF1KSD GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG
              160       170       180       190       200       210

      330       340       350       360       370       380        
pF1KSD TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV
              220       230       240       250       260       270

      390       400       410       420       430       440        
pF1KSD DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH
              280       290       300       310       320       330

      450       460       470       480       490       500        
pF1KSD FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL
              340       350       360       370       380       390

      510       520       530       540       550       560        
pF1KSD ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL
              400       410       420       430       440       450

      570       580       590       600       610       620        
pF1KSD YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL
              460       470       480       490       500       510

      630       640       650       660       670       680        
pF1KSD MWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM
              520       530       540       550       560       570

      690       700       710       720       730       740        
pF1KSD LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK
              580       590       600       610       620       630

      750       760       770       780       790       800        
pF1KSD EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH
              640       650       660       670       680       690

      810       820       830       840       850       860        
pF1KSD FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE
              700       710       720       730       740       750

      870       880       890       900       910       920        
pF1KSD QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS
              760       770       780       790       800       810

      930       940       950       960       970       980        
pF1KSD ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD
              820       830       840       850       860       870

      990      1000      1010      1020      1030      1040        
pF1KSD RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS
              880       890       900       910       920       930

     1050
pF1KSD LA
       ::
NP_001 LA
         

>>XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ubi  (924 aa)
 initn: 6167 init1: 3497 opt: 6155  Z-score: 7076.9  bits: 1320.9 E(85289):    0
Smith-Waterman score: 6155; 99.1% identity (99.1% similar) in 932 aa overlap (119-1050:1-924)

       90       100       110       120       130       140        
pF1KSD VACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWH
                                     ::::::::::::::::::::::::::::::
XP_016                               MTTEDSVAVPRLIQKLNQQTILQVSCGNWH
                                             10        20        30

      150       160       170       180       190       200        
pF1KSD CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLS
               40        50        60        70        80        90

      210       220       230       240       250       260        
pF1KSD GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGA
              100       110       120       130       140       150

      270       280       290       300       310       320        
pF1KSD GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG
              160       170       180       190       200       210

      330       340       350       360       370       380        
pF1KSD TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAV
              220       230       240       250       260       270

      390       400       410       420       430       440        
pF1KSD DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEH
              280       290       300       310       320       330

      450       460       470       480       490       500        
pF1KSD FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYL
              340       350       360       370       380       390

      510       520       530       540       550       560        
pF1KSD ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVL
              400       410       420       430       440       450

      570       580       590       600       610       620        
pF1KSD YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYL
              460       470       480       490       500       510

      630       640       650       660       670       680        
pF1KSD MWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM
       :::::::::        :::::::::::::::::::::::::::::::::::::::::::
XP_016 MWFLHQAGM--------DTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFM
                      520       530       540       550       560  

      690       700       710       720       730       740        
pF1KSD LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTK
            570       580       590       600       610       620  

      750       760       770       780       790       800        
pF1KSD EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLH
            630       640       650       660       670       680  

      810       820       830       840       850       860        
pF1KSD FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIE
            690       700       710       720       730       740  

      870       880       890       900       910       920        
pF1KSD QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPS
            750       760       770       780       790       800  

      930       940       950       960       970       980        
pF1KSD ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSD
            810       820       830       840       850       860  

      990      1000      1010      1020      1030      1040        
pF1KSD RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFS
            870       880       890       900       910       920  

     1050
pF1KSD LA
       ::
XP_016 LA
         

>>XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ubi  (903 aa)
 initn: 6393 init1: 5979 opt: 5982  Z-score: 6878.0  bits: 1284.1 E(85289):    0
Smith-Waterman score: 5982; 98.4% identity (99.3% similar) in 903 aa overlap (1-901:1-902)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
              790       800       810       820       830       840

              850       860       870       880         890        
pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQ--EFVDAYVNYVF
       ::::::::::::::::::::::::::::::::::::::::::::::.  .: : .. . :
XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRKKNDFED-FAVFRF
              850       860       870       880       890          

      900       910       920       930       940       950        
pF1KSD QISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSAT
       ...                                                         
XP_005 RLTR                                                        
     900                                                           

>>XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ubi  (896 aa)
 initn: 5976 init1: 5976 opt: 5976  Z-score: 6871.1  bits: 1282.8 E(85289):    0
Smith-Waterman score: 5976; 100.0% identity (100.0% similar) in 886 aa overlap (1-886:1-886)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
       ::::::::::::::::::::::::::::::::::::::::::::::              
XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRLSKKPQLWGK    
              850       860       870       880       890          

              910       920       930       940       950       960
pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP

>>XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ubi  (993 aa)
 initn: 4586 init1: 4586 opt: 4601  Z-score: 5288.7  bits: 990.2 E(85289):    0
Smith-Waterman score: 6579; 94.6% identity (94.6% similar) in 1050 aa overlap (1-1050:1-993)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
       ::::::::::::::::                                            
XP_005 AKTKMLQTDAELQMQV--------------------------------------------
              670                                                  

              730       740       750       760       770       780
pF1KSD IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
                    :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -------------IFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
                     680       690       700       710       720   

              790       800       810       820       830       840
pF1KSD CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
           730       740       750       760       770       780   

              850       860       870       880       890       900
pF1KSD LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
           790       800       810       820       830       840   

              910       920       930       940       950       960
pF1KSD SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
           850       860       870       880       890       900   

              970       980       990      1000      1010      1020
pF1KSD TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
           910       920       930       940       950       960   

             1030      1040      1050
pF1KSD LLDLPKYSSKEILSARLTQALDNYEGFSLA
       ::::::::::::::::::::::::::::::
XP_005 LLDLPKYSSKEILSARLTQALDNYEGFSLA
           970       980       990   

>>NP_071362 (OMIM: 609248) probable E3 ubiquitin-protein  (1057 aa)
 initn: 3818 init1: 2042 opt: 3972  Z-score: 4564.7  bits: 856.3 E(85289):    0
Smith-Waterman score: 3972; 56.0% identity (78.7% similar) in 1057 aa overlap (1-1049:1-1056)

               10        20        30        40        50        60
pF1KSD MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
       :::::  :.:: :..   . :: ::.   :. .. :..:.::  :.::.:.:: ::::: 
NP_071 MLCWGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
       :  ::::::.  .::::. ::  :.:. :.:::.:.:::.:.::...::  :::::::. 
NP_071 NDLGQLGHEKSRKKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
       .:. . ::: :..:..  :.::.:: .: :::.  .. : ::.:..:::::: .  .:.:
NP_071 SEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
       :: ..:: :::. ::::::::::.:.::::.:::: :. :::::.::.::  :  .: ::
NP_071 PQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
       .::.::: :::.:::.::: :::::::::. :::::.: . :.:::.:.::::: ::.::
NP_071 SQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
       :::::: ::::::: ::.:: :. :::::: : : : :  ::: :  ..::     :  .
NP_071 CGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTSNRKSPFTVKGNWYPYNGQCLPDIDSEE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
       :  ::.:::::::.:   :. .: .:  :::  : ..    .:.  :  : .  : .  .
NP_071 YFCVKRIFSGGDQSFSHYSSPQNCGPPDDFRCPNPTKQIWTVNEALIQKWLSYPSGRFPV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
       .  : .   .::..: :::::  . :.:..:. .. :.:.:..:.::.::.. .: .: .
NP_071 EIANEIDGTFSSSGCLNGSFLAVSNDDHYRTGTRFSGVDMNAARLLFHKLIQPDHPQISQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
       :.  :.:. :::.:.:: :::::.:.:: ::: ::..::. . :..::.. :.. :.  :
NP_071 QVAASLEKNLIPKLTSSLPDVEALRFYLTLPECPLMSDSNNFTTIAIPFGTALVNLEKAP
              490       500       510       520       530       540

              550       560       570       580          590       
pF1KSD SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPV---LFNNYITAALKLLEKL
        :::.:::: . :  :.:.:.:.: .:..::.  :  . :    .::... .:::.:: :
NP_071 LKVLENWWSVLEPPLFLKIVELFKEVVVHLLKLYKIGIPPSERRIFNSFLHTALKVLEIL
              550       560       570       580       590       600

       600        610       620       630        640          650  
pF1KSD YKVNLKVKHV-EYDTFYIPEISNLVDIQEDYLMWFLHQA-GMKARPSIIQ--DT-VTLCS
       ..:: :. .. .:: ::: :...:.::..::. :  .:: :: .  .. .  :  ::.:.
NP_071 HRVNEKMGQIIQYDKFYIHEVQELIDIRNDYINWVQQQAYGMDVNHGLTELADIPVTICT
              610       620       630       640       650       660

            660       670       680       690       700       710  
pF1KSD YPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLV
       :::.::::::: .::::: ::::.:.. :. :::  :. :  . . .: :.: :::.:.:
NP_071 YPFVFDAQAKTTLLQTDAVLQMQMAIDQAHRQNVSSLF-LPVIESVNPCLILVVRRENIV
              670       680       690        700       710         

            720       730       740       750       760       770  
pF1KSD GDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDS
       :::.. :   ..:: :::::::: ::.::::::: ::::::...:::.: :::: ::.::
NP_071 GDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS
     720       730       740       750       760       770         

            780       790       800       810       820       830  
pF1KSD NLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSP
        :.::::  : . . :::::. ::::::: :.::::::::::::::. ::.:.::::: :
NP_071 RLIWFSDKTFEDSDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMP
     780       790       800       810       820       830         

            840       850       860       870       880       890  
pF1KSD TEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDA
         :::.:.::::: .:.::::::::::  :..:. : :.:. .: ...: :.::::::::
NP_071 DVGRSMQQLLDYPEDDIEETFCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDA
     840       850       860       870       880       890         

            900       910       920       930       940       950  
pF1KSD YVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYK
       ::.:.:. ::   . :: .:: :::::::: ::::.::.::..::.::.:.:::... ::
NP_071 YVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYK
     900       910       920       930       940       950         

            960       970       980       990      1000      1010  
pF1KSD GDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYL
       :.: : :::.:.:::.:::.::::::.::::::::::::: :: ::..:::::..:::::
NP_071 GEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSLKLVIQSTGGGEEYL
     960       970       980       990      1000      1010         

           1020      1030      1040      1050
pF1KSD PVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSLA
       ::.:::.::::::::. :: : ..: ::.:. ::::: 
NP_071 PVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI
    1020      1030      1040      1050       




1050 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:30:10 2016 done: Wed Nov  2 23:30:12 2016
 Total Scan time: 11.930 Total Display time:  0.480

Function used was FASTA [36.3.4 Apr, 2011]
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