Result of FASTA (omim) for
pF1KSDA0037
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0037, 1080 aa
1>>>pF1KSDA0037 1080 - 1080 aa - 1080 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8733+/-0.000386; mu= 14.0947+/- 0.024
mean_var=90.9567+/-18.409, 0's: 0 Z-trim(114.3): 123 B-trim: 230 in 1/54
Lambda= 0.134480
statistics sampled from 23922 (24047) to 23922 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.282), width: 16
Scan time: 12.830
The best scores are: opt bits E(85289)
NP_001105 (OMIM: 600385) adenylate cyclase type 7 (1080) 7282 1423.6 0
XP_016878384 (OMIM: 600385) PREDICTED: adenylate c (1080) 7282 1423.6 0
XP_011521142 (OMIM: 600385) PREDICTED: adenylate c (1086) 7260 1419.3 0
XP_011521140 (OMIM: 600385) PREDICTED: adenylate c (1086) 7260 1419.3 0
XP_011521139 (OMIM: 600385) PREDICTED: adenylate c (1086) 7260 1419.3 0
XP_011521138 (OMIM: 600385) PREDICTED: adenylate c (1086) 7260 1419.3 0
XP_011521141 (OMIM: 600385) PREDICTED: adenylate c (1086) 7260 1419.3 0
XP_011521137 (OMIM: 600385) PREDICTED: adenylate c (1086) 7260 1419.3 0
XP_011521144 (OMIM: 600385) PREDICTED: adenylate c (1086) 7260 1419.3 0
XP_016878385 (OMIM: 600385) PREDICTED: adenylate c ( 886) 5950 1165.1 0
XP_016878386 (OMIM: 600385) PREDICTED: adenylate c ( 886) 5950 1165.1 0
XP_016878388 (OMIM: 600385) PREDICTED: adenylate c ( 723) 4834 948.6 0
XP_016878387 (OMIM: 600385) PREDICTED: adenylate c ( 734) 4832 948.2 0
NP_001272986 (OMIM: 600385) adenylate cyclase type ( 734) 4832 948.2 0
NP_065433 (OMIM: 103071) adenylate cyclase type 2 (1091) 3793 746.7 1.7e-214
NP_001185521 (OMIM: 600292) adenylate cyclase type (1077) 3461 682.2 4.2e-195
NP_001185497 (OMIM: 600292) adenylate cyclase type (1077) 3461 682.2 4.2e-195
NP_640340 (OMIM: 600292) adenylate cyclase type 4 (1077) 3461 682.2 4.2e-195
XP_011512244 (OMIM: 103071) PREDICTED: adenylate c (1045) 2218 441.1 1.6e-122
NP_001186571 (OMIM: 600293,606703) adenylate cycla ( 911) 1809 361.7 1.1e-98
NP_899200 (OMIM: 600293,606703) adenylate cyclase (1261) 1809 361.8 1.5e-98
XP_006719273 (OMIM: 600294,616287) PREDICTED: aden (1168) 1795 359.0 9e-98
NP_056085 (OMIM: 600294,616287) adenylate cyclase (1168) 1795 359.0 9e-98
XP_011530795 (OMIM: 600291) PREDICTED: adenylate c (1140) 1587 318.7 1.2e-85
XP_016858678 (OMIM: 600291) PREDICTED: adenylate c (1139) 1586 318.5 1.4e-85
NP_001307542 (OMIM: 600291) adenylate cyclase type (1145) 1585 318.3 1.6e-85
NP_004027 (OMIM: 600291) adenylate cyclase type 3 (1144) 1582 317.7 2.4e-85
XP_016858681 (OMIM: 600291) PREDICTED: adenylate c ( 904) 1405 283.3 4.3e-75
XP_016858682 (OMIM: 600291) PREDICTED: adenylate c ( 903) 1402 282.8 6.4e-75
XP_016858679 (OMIM: 600291) PREDICTED: adenylate c (1098) 1135 231.0 3e-59
XP_016858676 (OMIM: 600291) PREDICTED: adenylate c (1163) 1008 206.3 8.2e-52
XP_011530793 (OMIM: 600291) PREDICTED: adenylate c (1164) 1008 206.3 8.2e-52
XP_016868495 (OMIM: 103070) PREDICTED: adenylate c (1155) 966 198.2 2.3e-49
XP_016868496 (OMIM: 103070) PREDICTED: adenylate c ( 646) 962 197.3 2.3e-49
XP_006716564 (OMIM: 103070) PREDICTED: adenylate c (1185) 966 198.2 2.4e-49
XP_005250826 (OMIM: 103070) PREDICTED: adenylate c (1221) 964 197.8 3.2e-49
NP_001106 (OMIM: 103070) adenylate cyclase type 8 (1251) 964 197.8 3.3e-49
XP_006713547 (OMIM: 600293,606703) PREDICTED: aden ( 845) 913 187.9 2.2e-46
XP_011510663 (OMIM: 600293,606703) PREDICTED: aden ( 845) 913 187.9 2.2e-46
XP_016861129 (OMIM: 600293,606703) PREDICTED: aden ( 845) 913 187.9 2.2e-46
XP_006713546 (OMIM: 600293,606703) PREDICTED: aden ( 919) 913 187.9 2.3e-46
XP_016861128 (OMIM: 600293,606703) PREDICTED: aden ( 920) 913 187.9 2.3e-46
XP_016861127 (OMIM: 600293,606703) PREDICTED: aden ( 920) 913 187.9 2.3e-46
XP_011510662 (OMIM: 600293,606703) PREDICTED: aden ( 923) 913 187.9 2.4e-46
XP_005247135 (OMIM: 600293,606703) PREDICTED: aden ( 936) 913 187.9 2.4e-46
XP_011510661 (OMIM: 600293,606703) PREDICTED: aden ( 953) 913 187.9 2.4e-46
XP_005247134 (OMIM: 600293,606703) PREDICTED: aden (1286) 913 187.9 3.2e-46
XP_011530796 (OMIM: 600291) PREDICTED: adenylate c (1120) 879 181.3 2.7e-44
XP_016858677 (OMIM: 600291) PREDICTED: adenylate c (1149) 879 181.3 2.8e-44
XP_011530794 (OMIM: 600291) PREDICTED: adenylate c (1150) 879 181.3 2.8e-44
>>NP_001105 (OMIM: 600385) adenylate cyclase type 7 isof (1080 aa)
initn: 7282 init1: 7282 opt: 7282 Z-score: 7630.2 bits: 1423.6 E(85289): 0
Smith-Waterman score: 7282; 100.0% identity (100.0% similar) in 1080 aa overlap (1-1080:1-1080)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN
1030 1040 1050 1060 1070 1080
>>XP_016878384 (OMIM: 600385) PREDICTED: adenylate cycla (1080 aa)
initn: 7282 init1: 7282 opt: 7282 Z-score: 7630.2 bits: 1423.6 E(85289): 0
Smith-Waterman score: 7282; 100.0% identity (100.0% similar) in 1080 aa overlap (1-1080:1-1080)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKFQGLGLN
1030 1040 1050 1060 1070 1080
>>XP_011521142 (OMIM: 600385) PREDICTED: adenylate cycla (1086 aa)
initn: 7102 init1: 6962 opt: 7260 Z-score: 7607.1 bits: 1419.3 E(85289): 0
Smith-Waterman score: 7260; 99.4% identity (99.4% similar) in 1086 aa overlap (1-1080:1-1086)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD RMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 RMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
1030 1040 1050 1060 1070 1080
1080
pF1KSD QGLGLN
::::::
XP_011 QGLGLN
>>XP_011521140 (OMIM: 600385) PREDICTED: adenylate cycla (1086 aa)
initn: 7102 init1: 6962 opt: 7260 Z-score: 7607.1 bits: 1419.3 E(85289): 0
Smith-Waterman score: 7260; 99.4% identity (99.4% similar) in 1086 aa overlap (1-1080:1-1086)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD RMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 RMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
1030 1040 1050 1060 1070 1080
1080
pF1KSD QGLGLN
::::::
XP_011 QGLGLN
>>XP_011521139 (OMIM: 600385) PREDICTED: adenylate cycla (1086 aa)
initn: 7102 init1: 6962 opt: 7260 Z-score: 7607.1 bits: 1419.3 E(85289): 0
Smith-Waterman score: 7260; 99.4% identity (99.4% similar) in 1086 aa overlap (1-1080:1-1086)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD RMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 RMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
1030 1040 1050 1060 1070 1080
1080
pF1KSD QGLGLN
::::::
XP_011 QGLGLN
>>XP_011521138 (OMIM: 600385) PREDICTED: adenylate cycla (1086 aa)
initn: 7102 init1: 6962 opt: 7260 Z-score: 7607.1 bits: 1419.3 E(85289): 0
Smith-Waterman score: 7260; 99.4% identity (99.4% similar) in 1086 aa overlap (1-1080:1-1086)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD RMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 RMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
1030 1040 1050 1060 1070 1080
1080
pF1KSD QGLGLN
::::::
XP_011 QGLGLN
>>XP_011521141 (OMIM: 600385) PREDICTED: adenylate cycla (1086 aa)
initn: 7102 init1: 6962 opt: 7260 Z-score: 7607.1 bits: 1419.3 E(85289): 0
Smith-Waterman score: 7260; 99.4% identity (99.4% similar) in 1086 aa overlap (1-1080:1-1086)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD RMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 RMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
1030 1040 1050 1060 1070 1080
1080
pF1KSD QGLGLN
::::::
XP_011 QGLGLN
>>XP_011521137 (OMIM: 600385) PREDICTED: adenylate cycla (1086 aa)
initn: 7102 init1: 6962 opt: 7260 Z-score: 7607.1 bits: 1419.3 E(85289): 0
Smith-Waterman score: 7260; 99.4% identity (99.4% similar) in 1086 aa overlap (1-1080:1-1086)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD RMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 RMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
1030 1040 1050 1060 1070 1080
1080
pF1KSD QGLGLN
::::::
XP_011 QGLGLN
>>XP_011521144 (OMIM: 600385) PREDICTED: adenylate cycla (1086 aa)
initn: 7102 init1: 6962 opt: 7260 Z-score: 7607.1 bits: 1419.3 E(85289): 0
Smith-Waterman score: 7260; 99.4% identity (99.4% similar) in 1086 aa overlap (1-1080:1-1086)
10 20 30 40 50 60
pF1KSD MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHQAILGMAFLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAWEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQLASDCSPKEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMCQAIKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEAT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISER
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASSKTRALCEPLP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCCGQGLGNLTKP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKKFKKEHEEFET
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHENQELERQHAH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYDIWGNTVNVAS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD RMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 RMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFVCTDTAKF
1030 1040 1050 1060 1070 1080
1080
pF1KSD QGLGLN
::::::
XP_011 QGLGLN
>>XP_016878385 (OMIM: 600385) PREDICTED: adenylate cycla (886 aa)
initn: 5792 init1: 5652 opt: 5950 Z-score: 6235.0 bits: 1165.1 E(85289): 0
Smith-Waterman score: 5950; 99.3% identity (99.3% similar) in 886 aa overlap (201-1080:1-886)
180 190 200 210 220 230
pF1KSD TPSVRVGLQLLANAVIFLCGNLTGAFHKHQMQDASRDLFTYTVKCIQIRRKLRIEKRQQE
::::::::::::::::::::::::::::::
XP_016 MQDASRDLFTYTVKCIQIRRKLRIEKRQQE
10 20 30
240 250 260 270 280 290
pF1KSD NLLLSVLPAHISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLLSVLPAHISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQNVSILYADIVGFTQ
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD LASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKM
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD GLDMCQAIKQVREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLDMCQAIKQVREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGV
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD PGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRP
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD KGDAALKMRASVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGDAALKMRASVRMTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTP
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD DRSMSPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRSMSPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPI
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD PRARHDFACASLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRARHDFACASLIFVCILLVHVLLMPRTAALGVSFGLVACVLGLVLGLCFATKFSRCCPA
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD RGTLCTISERVETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGTLCTISERVETQPLLRLTLAVLTIGSLLTVAIINLPLMPFQVPELPVGNETGLLAASS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD KTRALCEPLPYYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTRALCEPLPYYTCSCVLGFIACSVFLRMSLEPKVVLLTVALVAYLVLFNLSPCWQWDCC
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD GQGLGNLTKPNGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQGLGNLTKPNGTTSGTPSCSWKDLKTMTNFYLVLFYITLLTLSRQIDYYCRLDCLWKKK
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD FKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFASVPDFKV
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD FYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHE
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD NQELERQHAHIGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQELERQHAHIGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYD
760 770 780 790 800 810
1020 1030 1040 1050 1060
pF1KSD IWGNTVNVASRMESTGELGKIQV------TEETCTILQGLGYSCECRGLINVKGKGELRT
::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_016 IWGNTVNVASRMESTGELGKIQVSLPFQVTEETCTILQGLGYSCECRGLINVKGKGELRT
820 830 840 850 860 870
1070 1080
pF1KSD YFVCTDTAKFQGLGLN
::::::::::::::::
XP_016 YFVCTDTAKFQGLGLN
880
1080 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:34:14 2016 done: Wed Nov 2 23:34:16 2016
Total Scan time: 12.830 Total Display time: 0.380
Function used was FASTA [36.3.4 Apr, 2011]