FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0039, 466 aa
  1>>>pF1KSDA0039 466 - 466 aa - 466 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.1993+/-0.000385; mu= -12.8280+/- 0.024
 mean_var=322.4515+/-64.369, 0's: 0 Z-trim(123.2): 3  B-trim: 0 in 0/59
 Lambda= 0.071424
 statistics sampled from 42487 (42490) to 42487 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.498), width:  16
 Scan time: 11.480

The best scores are:                                      opt bits E(85289)
NP_006582 (OMIM: 611415) DNA polymerase delta subu ( 466) 3009 323.2 9.3e-88
XP_011543036 (OMIM: 611415) PREDICTED: DNA polymer ( 448) 2881 310.0 8.4e-84
XP_005273773 (OMIM: 611415) PREDICTED: DNA polymer ( 425) 2586 279.6 1.1e-74


>>NP_006582 (OMIM: 611415) DNA polymerase delta subunit   (466 aa)
 initn: 3009 init1: 3009 opt: 3009  Z-score: 1696.5  bits: 323.2 E(85289): 9.3e-88
Smith-Waterman score: 3009; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)

               10        20        30        40        50        60
pF1KSD MADQLYLENIDEFVTDQNKIVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MADQLYLENIDEFVTDQNKIVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD ILKSNLQNCSKFSAIQCAAAVPRAPAESSSSSKKFEQSHLHMSSETQANNELTTNGHGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ILKSNLQNCSKFSAIQCAAAVPRAPAESSSSSKKFEQSHLHMSSETQANNELTTNGHGPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ASKQVSQQPKGIMGMFASKAAAKTQETNKETKTEAKEVTNASAAGNKAPGKGNMMSNFFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ASKQVSQQPKGIMGMFASKAAAKTQETNKETKTEAKEVTNASAAGNKAPGKGNMMSNFFG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD KAAMNKFKVNLDSEQAVKEEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KAAMNKFKVNLDSEQAVKEEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPPLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPPLE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVTEKVYESESCTDSEEELNMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVTEKVYESESCTDSEEELNMK
              370       380       390       400       410       420

              430       440       450       460      
pF1KSD TSSVHRPPAMTVKKEPREERKGPKKGTAALGKANRQVSITGFFQRK
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TSSVHRPPAMTVKKEPREERKGPKKGTAALGKANRQVSITGFFQRK
              430       440       450       460      

>>XP_011543036 (OMIM: 611415) PREDICTED: DNA polymerase   (448 aa)
 initn: 2881 init1: 2881 opt: 2881  Z-score: 1625.5  bits: 310.0 E(85289): 8.4e-84
Smith-Waterman score: 2881; 100.0% identity (100.0% similar) in 446 aa overlap (21-466:3-448)

               10        20        30        40        50        60
pF1KSD MADQLYLENIDEFVTDQNKIVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVT
                           ::::::::::::::::::::::::::::::::::::::::
XP_011                   MDVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVT
                                 10        20        30        40  

               70        80        90       100       110       120
pF1KSD YLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYD
             50        60        70        80        90       100  

              130       140       150       160       170       180
pF1KSD ILKSNLQNCSKFSAIQCAAAVPRAPAESSSSSKKFEQSHLHMSSETQANNELTTNGHGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILKSNLQNCSKFSAIQCAAAVPRAPAESSSSSKKFEQSHLHMSSETQANNELTTNGHGPP
            110       120       130       140       150       160  

              190       200       210       220       230       240
pF1KSD ASKQVSQQPKGIMGMFASKAAAKTQETNKETKTEAKEVTNASAAGNKAPGKGNMMSNFFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASKQVSQQPKGIMGMFASKAAAKTQETNKETKTEAKEVTNASAAGNKAPGKGNMMSNFFG
            170       180       190       200       210       220  

              250       260       270       280       290       300
pF1KSD KAAMNKFKVNLDSEQAVKEEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAMNKFKVNLDSEQAVKEEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKKR
            230       240       250       260       270       280  

              310       320       330       340       350       360
pF1KSD GKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPPLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPPLE
            290       300       310       320       330       340  

              370       380       390       400       410       420
pF1KSD PVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVTEKVYESESCTDSEEELNMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVTEKVYESESCTDSEEELNMK
            350       360       370       380       390       400  

              430       440       450       460      
pF1KSD TSSVHRPPAMTVKKEPREERKGPKKGTAALGKANRQVSITGFFQRK
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSVHRPPAMTVKKEPREERKGPKKGTAALGKANRQVSITGFFQRK
            410       420       430       440        

>>XP_005273773 (OMIM: 611415) PREDICTED: DNA polymerase   (425 aa)
 initn: 2582 init1: 2582 opt: 2586  Z-score: 1461.6  bits: 279.6 E(85289): 1.1e-74
Smith-Waterman score: 2586; 95.1% identity (97.4% similar) in 426 aa overlap (1-426:1-425)

               10        20        30        40        50        60
pF1KSD MADQLYLENIDEFVTDQNKIVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADQLYLENIDEFVTDQNKIVTYKWLSYTLGVHVNQAKQMLYDYVERKRKENSGAQLHVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLVSGSLIQNGHSCHKVAVVREDKLEAVKSKLAVTASIHVYSIQKAMLKDSGPLFNTDYD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD ILKSNLQNCSKFSAIQCAAAVPRAPAESSSSSKKFEQSHLHMSSETQANNELTTNGHGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILKSNLQNCSKFSAIQCAAAVPRAPAESSSSSKKFEQSHLHMSSETQANNELTTNGHGPP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ASKQVSQQPKGIMGMFASKAAAKTQETNKETKTEAKEVTNASAAGNKAPGKGNMMSNFFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASKQVSQQPKGIMGMFASKAAAKTQETNKETKTEAKEVTNASAAGNKAPGKGNMMSNFFG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD KAAMNKFKVNLDSEQAVKEEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAAMNKFKVNLDSEQAVKEEKIVEQPTVSVTEPKLATPAGLKKSSKKAEPVKVLQKEKKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPPLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKRVALSDDETKETENMRKKRRRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPPLE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD PVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVTEKVYESESCTDSEEELNMK
       ::::::::::::::::::::::::::::::::::::::::.  . .:.:    :. ..: 
XP_005 PVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVVLDM-QSHSLDILEHYVEMP
              370       380       390       400        410         

              430       440       450       460      
pF1KSD TSSVHRPPAMTVKKEPREERKGPKKGTAALGKANRQVSITGFFQRK
        . ..:                                        
XP_005 IQRLER                                        
     420                                             




466 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:35:24 2016 done: Wed Nov  2 23:35:25 2016
 Total Scan time: 11.480 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]