FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0049, 966 aa 1>>>pF1KSDA0049 966 - 966 aa - 966 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3973+/-0.000949; mu= 7.9833+/- 0.058 mean_var=168.7833+/-33.677, 0's: 0 Z-trim(111.7): 19 B-trim: 0 in 0/50 Lambda= 0.098721 statistics sampled from 12598 (12609) to 12598 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.387), width: 16 Scan time: 4.960 The best scores are: opt bits E(32554) CCDS45694.1 NBR1 gene_id:4077|Hs108|chr17 ( 966) 6477 935.2 0 CCDS77037.1 NBR1 gene_id:4077|Hs108|chr17 ( 937) 6095 880.7 0 CCDS77038.1 NBR1 gene_id:4077|Hs108|chr17 ( 837) 5386 779.7 0 >>CCDS45694.1 NBR1 gene_id:4077|Hs108|chr17 (966 aa) initn: 6477 init1: 6477 opt: 6477 Z-score: 4992.3 bits: 935.2 E(32554): 0 Smith-Waterman score: 6477; 100.0% identity (100.0% similar) in 966 aa overlap (1-966:1-966) 10 20 30 40 50 60 pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND 910 920 930 940 950 960 pF1KSD WYSQRY :::::: CCDS45 WYSQRY >>CCDS77037.1 NBR1 gene_id:4077|Hs108|chr17 (937 aa) initn: 6095 init1: 6095 opt: 6095 Z-score: 4698.5 bits: 880.7 E(32554): 0 Smith-Waterman score: 6095; 100.0% identity (100.0% similar) in 909 aa overlap (1-909:1-909) 10 20 30 40 50 60 pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND ::::::::: CCDS77 FAGPPVTAQGLWGLLSFLHLAKKCFFLKAPSEAFSWF 910 920 930 >>CCDS77038.1 NBR1 gene_id:4077|Hs108|chr17 (837 aa) initn: 5386 init1: 5386 opt: 5386 Z-score: 4153.5 bits: 779.7 E(32554): 0 Smith-Waterman score: 5555; 97.5% identity (97.5% similar) in 854 aa overlap (1-854:1-833) 10 20 30 40 50 60 pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS ::::::::::::::::::::::::::::::::::: :::: CCDS77 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMV---------------------SINS 10 20 30 70 80 90 100 110 120 pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP 400 410 420 430 440 450 490 500 510 520 530 540 pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN 460 470 480 490 500 510 550 560 570 580 590 600 pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD 580 590 600 610 620 630 670 680 690 700 710 720 pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG 700 710 720 730 740 750 790 800 810 820 830 840 pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV 760 770 780 790 800 810 850 860 870 880 890 900 pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL :::::::::::::: CCDS77 TIPEVSSVPDQIRGANNF 820 830 966 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:38:06 2016 done: Wed Nov 2 23:38:07 2016 Total Scan time: 4.960 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]