Result of FASTA (omim) for
pF1KSDA0049
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0049, 966 aa
1>>>pF1KSDA0049 966 - 966 aa - 966 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7917+/-0.00037; mu= 5.7000+/- 0.023
mean_var=181.3261+/-36.056, 0's: 0 Z-trim(119.5): 34 B-trim: 0 in 0/56
Lambda= 0.095245
statistics sampled from 33544 (33578) to 33544 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.394), width: 16
Scan time: 12.490
The best scores are: opt bits E(85289)
NP_114068 (OMIM: 166945) next to BRCA1 gene 1 prot ( 966) 6477 902.9 0
NP_005890 (OMIM: 166945) next to BRCA1 gene 1 prot ( 966) 6477 902.9 0
XP_016880131 (OMIM: 166945) PREDICTED: next to BRC ( 966) 6477 902.9 0
XP_011523115 (OMIM: 166945) PREDICTED: next to BRC ( 966) 6477 902.9 0
NP_001278500 (OMIM: 166945) next to BRCA1 gene 1 p ( 937) 6095 850.4 0
NP_001278501 (OMIM: 166945) next to BRCA1 gene 1 p ( 837) 5386 753.0 1.5e-216
XP_016880132 (OMIM: 166945) PREDICTED: next to BRC ( 896) 4064 571.3 7.5e-162
XP_006721966 (OMIM: 166945) PREDICTED: next to BRC ( 896) 4064 571.3 7.5e-162
XP_016880133 (OMIM: 166945) PREDICTED: next to BRC ( 896) 4064 571.3 7.5e-162
>>NP_114068 (OMIM: 166945) next to BRCA1 gene 1 protein (966 aa)
initn: 6477 init1: 6477 opt: 6477 Z-score: 4818.1 bits: 902.9 E(85289): 0
Smith-Waterman score: 6477; 100.0% identity (100.0% similar) in 966 aa overlap (1-966:1-966)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
910 920 930 940 950 960
pF1KSD WYSQRY
::::::
NP_114 WYSQRY
>>NP_005890 (OMIM: 166945) next to BRCA1 gene 1 protein (966 aa)
initn: 6477 init1: 6477 opt: 6477 Z-score: 4818.1 bits: 902.9 E(85289): 0
Smith-Waterman score: 6477; 100.0% identity (100.0% similar) in 966 aa overlap (1-966:1-966)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
910 920 930 940 950 960
pF1KSD WYSQRY
::::::
NP_005 WYSQRY
>>XP_016880131 (OMIM: 166945) PREDICTED: next to BRCA1 g (966 aa)
initn: 6477 init1: 6477 opt: 6477 Z-score: 4818.1 bits: 902.9 E(85289): 0
Smith-Waterman score: 6477; 100.0% identity (100.0% similar) in 966 aa overlap (1-966:1-966)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
910 920 930 940 950 960
pF1KSD WYSQRY
::::::
XP_016 WYSQRY
>>XP_011523115 (OMIM: 166945) PREDICTED: next to BRCA1 g (966 aa)
initn: 6477 init1: 6477 opt: 6477 Z-score: 4818.1 bits: 902.9 E(85289): 0
Smith-Waterman score: 6477; 100.0% identity (100.0% similar) in 966 aa overlap (1-966:1-966)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
910 920 930 940 950 960
pF1KSD WYSQRY
::::::
XP_011 WYSQRY
>>NP_001278500 (OMIM: 166945) next to BRCA1 gene 1 prote (937 aa)
initn: 6095 init1: 6095 opt: 6095 Z-score: 4534.7 bits: 850.4 E(85289): 0
Smith-Waterman score: 6095; 100.0% identity (100.0% similar) in 909 aa overlap (1-909:1-909)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
:::::::::
NP_001 FAGPPVTAQGLWGLLSFLHLAKKCFFLKAPSEAFSWF
910 920 930
>>NP_001278501 (OMIM: 166945) next to BRCA1 gene 1 prote (837 aa)
initn: 5386 init1: 5386 opt: 5386 Z-score: 4008.9 bits: 753.0 E(85289): 1.5e-216
Smith-Waterman score: 5555; 97.5% identity (97.5% similar) in 854 aa overlap (1-854:1-833)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::: ::::
NP_001 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMV---------------------SINS
10 20 30
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
520 530 540 550 560 570
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
580 590 600 610 620 630
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
640 650 660 670 680 690
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
700 710 720 730 740 750
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
760 770 780 790 800 810
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::
NP_001 TIPEVSSVPDQIRGANNF
820 830
>>XP_016880132 (OMIM: 166945) PREDICTED: next to BRCA1 g (896 aa)
initn: 4059 init1: 4059 opt: 4064 Z-score: 3026.7 bits: 571.3 E(85289): 7.5e-162
Smith-Waterman score: 5875; 92.8% identity (92.8% similar) in 966 aa overlap (1-966:1-896)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRL-----------
250 260 270 280
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
:
XP_016 -----------------------------------------------------------P
290
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
300 310 320 330 340 350
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
360 370 380 390 400 410
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
420 430 440 450 460 470
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
480 490 500 510 520 530
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
540 550 560 570 580 590
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
600 610 620 630 640 650
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
660 670 680 690 700 710
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
720 730 740 750 760 770
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
780 790 800 810 820 830
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
840 850 860 870 880 890
pF1KSD WYSQRY
::::::
XP_016 WYSQRY
>>XP_006721966 (OMIM: 166945) PREDICTED: next to BRCA1 g (896 aa)
initn: 4059 init1: 4059 opt: 4064 Z-score: 3026.7 bits: 571.3 E(85289): 7.5e-162
Smith-Waterman score: 5875; 92.8% identity (92.8% similar) in 966 aa overlap (1-966:1-896)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRL-----------
250 260 270 280
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
:
XP_006 -----------------------------------------------------------P
290
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
300 310 320 330 340 350
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
360 370 380 390 400 410
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
420 430 440 450 460 470
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
480 490 500 510 520 530
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
540 550 560 570 580 590
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
600 610 620 630 640 650
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
660 670 680 690 700 710
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
720 730 740 750 760 770
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
780 790 800 810 820 830
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
840 850 860 870 880 890
pF1KSD WYSQRY
::::::
XP_006 WYSQRY
>>XP_016880133 (OMIM: 166945) PREDICTED: next to BRCA1 g (896 aa)
initn: 4059 init1: 4059 opt: 4064 Z-score: 3026.7 bits: 571.3 E(85289): 7.5e-162
Smith-Waterman score: 5875; 92.8% identity (92.8% similar) in 966 aa overlap (1-966:1-896)
10 20 30 40 50 60
pF1KSD MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGEYEEALKMAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNFLKA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRL-----------
250 260 270 280
310 320 330 340 350 360
pF1KSD EKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLP
:
XP_016 -----------------------------------------------------------P
290
370 380 390 400 410 420
pF1KSD LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLT
300 310 320 330 340 350
430 440 450 460 470 480
pF1KSD LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDP
360 370 380 390 400 410
490 500 510 520 530 540
pF1KSD FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPSEESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKN
420 430 440 450 460 470
550 560 570 580 590 600
pF1KSD VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASERELYIPSVDLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIE
480 490 500 510 520 530
610 620 630 640 650 660
pF1KSD KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLD
540 550 560 570 580 590
670 680 690 700 710 720
pF1KSD AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDEEEEDELKDE
600 610 620 630 640 650
730 740 750 760 770 780
pF1KSD VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG
660 670 680 690 700 710
790 800 810 820 830 840
pF1KSD ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPV
720 730 740 750 760 770
850 860 870 880 890 900
pF1KSD TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAYKAL
780 790 800 810 820 830
910 920 930 940 950 960
pF1KSD FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAGPPVTAQPIISEDQTAALMAHLFEMGFCDRQLNLRLLKKHNYNILQVVTELLQLNNND
840 850 860 870 880 890
pF1KSD WYSQRY
::::::
XP_016 WYSQRY
966 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:38:07 2016 done: Wed Nov 2 23:38:09 2016
Total Scan time: 12.490 Total Display time: 0.280
Function used was FASTA [36.3.4 Apr, 2011]