Result of FASTA (omim) for
pF1KSDA0057
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0057, 370 aa
1>>>pF1KSDA0057 370 - 370 aa - 370 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9431+/-0.000463; mu= 18.4045+/- 0.028
mean_var=67.5170+/-13.680, 0's: 0 Z-trim(109.3): 36 B-trim: 0 in 0/51
Lambda= 0.156087
statistics sampled from 17452 (17488) to 17452 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.205), width: 16
Scan time: 6.580
The best scores are: opt bits E(85289)
NP_036420 (OMIM: 608485) translocating chain-assoc ( 370) 2499 572.2 6.6e-163
XP_011513307 (OMIM: 608485) PREDICTED: translocati ( 333) 2095 481.2 1.5e-135
NP_055109 (OMIM: 605190) translocating chain-assoc ( 374) 1342 311.7 1.8e-84
NP_001304733 (OMIM: 605190) translocating chain-as ( 343) 1234 287.3 3.5e-77
NP_001304734 (OMIM: 605190) translocating chain-as ( 288) 1067 249.6 6.4e-66
XP_016868756 (OMIM: 605190) PREDICTED: translocati ( 278) 988 231.8 1.4e-60
XP_016868755 (OMIM: 605190) PREDICTED: translocati ( 278) 988 231.8 1.4e-60
NP_859530 (OMIM: 606920) ceramide synthase 2 [Homo ( 380) 211 57.0 8.4e-08
XP_011507754 (OMIM: 606920) PREDICTED: ceramide sy ( 380) 211 57.0 8.4e-08
NP_071358 (OMIM: 606920) ceramide synthase 2 [Homo ( 380) 211 57.0 8.4e-08
XP_011507753 (OMIM: 606920) PREDICTED: ceramide sy ( 400) 211 57.0 8.8e-08
XP_011526595 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
XP_016882793 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
XP_011526593 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
XP_011526592 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
XP_011526594 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
XP_011526596 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
XP_016882792 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
NP_078828 (OMIM: 615334) ceramide synthase 4 [Homo ( 394) 208 56.3 1.4e-07
XP_011526597 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
XP_016882794 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 208 56.3 1.4e-07
NP_001317998 (OMIM: 615335) ceramide synthase 5 is ( 323) 180 49.9 9.4e-06
XP_016875691 (OMIM: 615335) PREDICTED: ceramide sy ( 334) 180 50.0 9.7e-06
NP_001268660 (OMIM: 615335) ceramide synthase 5 is ( 334) 180 50.0 9.7e-06
NP_001318000 (OMIM: 615335) ceramide synthase 5 is ( 381) 180 50.0 1.1e-05
NP_982288 (OMIM: 615336) ceramide synthase 6 isofo ( 384) 180 50.0 1.1e-05
NP_001317999 (OMIM: 615335) ceramide synthase 5 is ( 392) 180 50.0 1.1e-05
NP_001243055 (OMIM: 615336) ceramide synthase 6 is ( 392) 180 50.0 1.1e-05
NP_671723 (OMIM: 615335) ceramide synthase 5 isofo ( 392) 180 50.0 1.1e-05
XP_005269277 (OMIM: 615335) PREDICTED: ceramide sy ( 409) 180 50.0 1.1e-05
XP_016875693 (OMIM: 615335) PREDICTED: ceramide sy ( 290) 175 48.8 1.9e-05
XP_016859238 (OMIM: 615336) PREDICTED: ceramide sy ( 251) 174 48.5 2e-05
XP_016875694 (OMIM: 615335) PREDICTED: ceramide sy ( 237) 172 48.0 2.6e-05
NP_001318002 (OMIM: 615335) ceramide synthase 5 is ( 237) 172 48.0 2.6e-05
NP_001318001 (OMIM: 615335) ceramide synthase 5 is ( 248) 172 48.1 2.7e-05
>>NP_036420 (OMIM: 608485) translocating chain-associate (370 aa)
initn: 2499 init1: 2499 opt: 2499 Z-score: 3045.7 bits: 572.2 E(85289): 6.6e-163
Smith-Waterman score: 2499; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)
10 20 30 40 50 60
pF1KSD MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD ADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD QKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD AAQAWLMWRFIHSQLRHWREYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AAQAWLMWRFIHSQLRHWREYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGT
310 320 330 340 350 360
370
pF1KSD SPRTKKLKSP
::::::::::
NP_036 SPRTKKLKSP
370
>>XP_011513307 (OMIM: 608485) PREDICTED: translocating c (333 aa)
initn: 2095 init1: 2095 opt: 2095 Z-score: 2554.6 bits: 481.2 E(85289): 1.5e-135
Smith-Waterman score: 2095; 100.0% identity (100.0% similar) in 309 aa overlap (62-370:25-333)
40 50 60 70 80 90
pF1KSD CVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAV
::::::::::::::::::::::::::::::
XP_011 MYKYFIEIWPSITPTLRSGITEICDSETVHYHYGPKDLVTILFYIFITIILHAV
10 20 30 40 50
100 110 120 130 140 150
pF1KSD VQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDY
60 70 80 90 100 110
160 170 180 190 200 210
pF1KSD PHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLS
120 130 140 150 160 170
220 230 240 250 260 270
pF1KSD RLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGL
180 190 200 210 220 230
280 290 300 310 320 330
pF1KSD ARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQSAKRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQSAKRRV
240 250 260 270 280 290
340 350 360 370
pF1KSD PATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
:::::::::::::::::::::::::::::::::::::::
XP_011 PATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
300 310 320 330
>>NP_055109 (OMIM: 605190) translocating chain-associate (374 aa)
initn: 1316 init1: 1081 opt: 1342 Z-score: 1637.5 bits: 311.7 E(85289): 1.8e-84
Smith-Waterman score: 1342; 52.5% identity (81.6% similar) in 375 aa overlap (1-369:1-373)
10 20 30 40 50
pF1KSD MAFRRR-TKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVP
::.:.. ::: :..:.:::..::::: :... :.:::::.:::....:. :::...:
NP_055 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD TAD---SETVH-YHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFN
... .:.: :.:: :::.:..::....::.:::.:::.::::..:.:.::.::::::
NP_055 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD ESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHAL
::::: .:.. . .: .....:.:...: ::. ::: . ::.::::. ::::::::.
NP_055 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD PELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFY
:::::::..::.::::: :: ::: ::::::::::..:::.::.:.: .::::: .::::
NP_055 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD FADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCV
:..:. .: :: ::..: . ::. : :.::..:::::: ::: .: ::::.: :. :
NP_055 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LLLVCAAQAWLMWRFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVV
: .:..::..::.::. :::.:::. :. : .. :.. . .: :. . ::..
NP_055 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTL
310 320 330 340 350
360 370
pF1KSD KAENGTSPRTKKLKSP
.. . :::.:: ::
NP_055 TSNVADSPRNKKEKSS
360 370
>>NP_001304733 (OMIM: 605190) translocating chain-associ (343 aa)
initn: 1213 init1: 1081 opt: 1234 Z-score: 1506.6 bits: 287.3 E(85289): 3.5e-77
Smith-Waterman score: 1234; 52.3% identity (81.1% similar) in 344 aa overlap (31-369:1-342)
10 20 30 40 50 60
pF1KSD MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPT
. :.:::::.:::....:. :::...:.
NP_001 MVFLLGLMFEITAKASIIFVTLQYNVTLPA
10 20 30
70 80 90 100 110
pF1KSD AD---SETVH-YHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNE
.. .:.: :.:: :::.:..::....::.:::.:::.::::..:.:.::.:::::::
NP_001 TEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KSD SGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALP
:::: .:.. . .: .....:.:...: ::. ::: . ::.::::. ::::::::.:
NP_001 SGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFP
100 110 120 130 140 150
180 190 200 210 220 230
pF1KSD ELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYF
::::::..::.::::: :: ::: ::::::::::..:::.::.:.: .::::: .:::::
NP_001 ELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYF
160 170 180 190 200 210
240 250 260 270 280 290
pF1KSD ADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVL
..:. .: :: ::..: . ::. : :.::..:::::: ::: .: ::::.: :. ::
NP_001 SNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVL
220 230 240 250 260 270
300 310 320 330 340 350
pF1KSD LLVCAAQAWLMWRFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVVK
.:..::..::.::. :::.:::. :. : .. :.. . .: :. . ::..
NP_001 ASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTLT
280 290 300 310 320
360 370
pF1KSD AENGTSPRTKKLKSP
.. . :::.:: ::
NP_001 SNVADSPRNKKEKSS
330 340
>>NP_001304734 (OMIM: 605190) translocating chain-associ (288 aa)
initn: 1056 init1: 1016 opt: 1067 Z-score: 1304.4 bits: 249.6 E(85289): 6.4e-66
Smith-Waterman score: 1067; 53.6% identity (81.0% similar) in 289 aa overlap (82-369:1-287)
60 70 80 90 100 110
pF1KSD PQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKH
....::.:::.:::.::::..:.:.::.::
NP_001 MLVAIIIHAVIQEYMLDKINRRMHFSKTKH
10 20 30
120 130 140 150 160 170
pF1KSD SKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYW
::::::::: .:.. . .: .....:.:...: ::. ::: . ::.::::. :::::
NP_001 SKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYW
40 50 60 70 80 90
180 190 200 210 220 230
pF1KSD LHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTA
:::.:::::::..::.::::: :: ::: ::::::::::..:::.::.:.: .::::: .
NP_001 LHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHIS
100 110 120 130 140 150
240 250 260 270 280 290
pF1KSD RLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFC
:::::..:. .: :: ::..: . ::. : :.::..:::::: ::: .: ::::.:
NP_001 RLFYFSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAV
160 170 180 190 200 210
300 310 320 330 340 350
pF1KSD RLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHE
:. :: .:..::..::.::. :::.:::. :. : .. :.. . .: :. .
NP_001 RIAVLASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGV
220 230 240 250 260
360 370
pF1KSD NGVVKAENGTSPRTKKLKSP
::.. .. . :::.:: ::
NP_001 NGTLTSNVADSPRNKKEKSS
270 280
>>XP_016868756 (OMIM: 605190) PREDICTED: translocating c (278 aa)
initn: 984 init1: 944 opt: 988 Z-score: 1208.5 bits: 231.8 E(85289): 1.4e-60
Smith-Waterman score: 988; 53.3% identity (79.8% similar) in 272 aa overlap (99-369:8-277)
70 80 90 100 110 120
pF1KSD HYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSV
::..:.:.::.::::::::::: .:.. .
XP_016 MSPSQQQKINRRMHFSKTKHSKFNESGQLSAFYLFAC
10 20 30
130 140 150 160 170 180
pF1KSD IWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEI
.: .....:.:...: ::. ::: . ::.::::. ::::::::.:::::::..::.:
XP_016 VWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDI
40 50 60 70 80 90
190 200 210 220 230 240
pF1KSD PRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAW
:::: :: ::: ::::::::::..:::.::.:.: .::::: .:::::..:. .: :: :
XP_016 PRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLW
100 110 120 130 140 150
250 260 270 280 290 300
pF1KSD AAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMW
:..: . ::. : :.::..:::::: ::: .: ::::.: :. :: .:..::..::
XP_016 AVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMW
160 170 180 190 200 210
310 320 330 340 350 360
pF1KSD RFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKL
.::. :::.:::. :. : .. :.. . .: :. . ::.. .. . :::.::
XP_016 KFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTLTSNVADSPRNKKE
220 230 240 250 260 270
370
pF1KSD KSP
::
XP_016 KSS
>>XP_016868755 (OMIM: 605190) PREDICTED: translocating c (278 aa)
initn: 984 init1: 944 opt: 988 Z-score: 1208.5 bits: 231.8 E(85289): 1.4e-60
Smith-Waterman score: 988; 53.3% identity (79.8% similar) in 272 aa overlap (99-369:8-277)
70 80 90 100 110 120
pF1KSD HYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSV
::..:.:.::.::::::::::: .:.. .
XP_016 MSPSQQQKINRRMHFSKTKHSKFNESGQLSAFYLFAC
10 20 30
130 140 150 160 170 180
pF1KSD IWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEI
.: .....:.:...: ::. ::: . ::.::::. ::::::::.:::::::..::.:
XP_016 VWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDI
40 50 60 70 80 90
190 200 210 220 230 240
pF1KSD PRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAW
:::: :: ::: ::::::::::..:::.::.:.: .::::: .:::::..:. .: :: :
XP_016 PRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLW
100 110 120 130 140 150
250 260 270 280 290 300
pF1KSD AAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMW
:..: . ::. : :.::..:::::: ::: .: ::::.: :. :: .:..::..::
XP_016 AVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMW
160 170 180 190 200 210
310 320 330 340 350 360
pF1KSD RFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKL
.::. :::.:::. :. : .. :.. . .: :. . ::.. .. . :::.::
XP_016 KFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTLTSNVADSPRNKKE
220 230 240 250 260 270
370
pF1KSD KSP
::
XP_016 KSS
>>NP_859530 (OMIM: 606920) ceramide synthase 2 [Homo sap (380 aa)
initn: 105 init1: 62 opt: 211 Z-score: 261.0 bits: 57.0 E(85289): 8.4e-08
Smith-Waterman score: 211; 25.5% identity (58.8% similar) in 204 aa overlap (113-312:132-328)
90 100 110 120 130 140
pF1KSD FITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLT
:: :.. .:.. . : . :.: . ..
NP_859 LLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFY
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD NPRSLWEDYP-HVHLPFQVKFFYLCQLA-YWLHALPELYFQKVRKEEIPRQLQYICLYLV
. ...:: :: . .: : ..:. .:. :: .: . :..... .:. . ..
NP_859 DMKKVWEGYPIQSTIPSQY-WYYMIELSFYW--SLLFSIASDVKRKDFKEQIIHHVATII
170 180 190 200 210
210 220 230 240 250
pF1KSD HIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENN--EKLFSAWAAVFGVTRLF
:. ... : : : ... :. :...:...:..: .: .: ...: ..: :: .:::
NP_859 LISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLV
220 230 240 250 260 270
260 270 280 290 300 310
pF1KSD ILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHW
:: . .: . :: ::.. . :: :. :.:. :. :
NP_859 ILPFWILHCTLVYPLELYPAFFGYYF-FNSM---MGVLQLLHIFWAYLILRMAHKFITGK
280 290 300 310 320 330
320 330 340 350 360 370
pF1KSD REYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
NP_859 LVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND
340 350 360 370 380
>>XP_011507754 (OMIM: 606920) PREDICTED: ceramide syntha (380 aa)
initn: 105 init1: 62 opt: 211 Z-score: 261.0 bits: 57.0 E(85289): 8.4e-08
Smith-Waterman score: 211; 25.5% identity (58.8% similar) in 204 aa overlap (113-312:132-328)
90 100 110 120 130 140
pF1KSD FITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLT
:: :.. .:.. . : . :.: . ..
XP_011 LLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFY
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD NPRSLWEDYP-HVHLPFQVKFFYLCQLA-YWLHALPELYFQKVRKEEIPRQLQYICLYLV
. ...:: :: . .: : ..:. .:. :: .: . :..... .:. . ..
XP_011 DMKKVWEGYPIQSTIPSQY-WYYMIELSFYW--SLLFSIASDVKRKDFKEQIIHHVATII
170 180 190 200 210
210 220 230 240 250
pF1KSD HIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENN--EKLFSAWAAVFGVTRLF
:. ... : : : ... :. :...:...:..: .: .: ...: ..: :: .:::
XP_011 LISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLV
220 230 240 250 260 270
260 270 280 290 300 310
pF1KSD ILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHW
:: . .: . :: ::.. . :: :. :.:. :. :
XP_011 ILPFWILHCTLVYPLELYPAFFGYYF-FNSM---MGVLQLLHIFWAYLILRMAHKFITGK
280 290 300 310 320 330
320 330 340 350 360 370
pF1KSD REYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
XP_011 LVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND
340 350 360 370 380
>>NP_071358 (OMIM: 606920) ceramide synthase 2 [Homo sap (380 aa)
initn: 105 init1: 62 opt: 211 Z-score: 261.0 bits: 57.0 E(85289): 8.4e-08
Smith-Waterman score: 211; 25.5% identity (58.8% similar) in 204 aa overlap (113-312:132-328)
90 100 110 120 130 140
pF1KSD FITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLT
:: :.. .:.. . : . :.: . ..
NP_071 LLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFY
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD NPRSLWEDYP-HVHLPFQVKFFYLCQLA-YWLHALPELYFQKVRKEEIPRQLQYICLYLV
. ...:: :: . .: : ..:. .:. :: .: . :..... .:. . ..
NP_071 DMKKVWEGYPIQSTIPSQY-WYYMIELSFYW--SLLFSIASDVKRKDFKEQIIHHVATII
170 180 190 200 210
210 220 230 240 250
pF1KSD HIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENN--EKLFSAWAAVFGVTRLF
:. ... : : : ... :. :...:...:..: .: .: ...: ..: :: .:::
NP_071 LISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLV
220 230 240 250 260 270
260 270 280 290 300 310
pF1KSD ILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHW
:: . .: . :: ::.. . :: :. :.:. :. :
NP_071 ILPFWILHCTLVYPLELYPAFFGYYF-FNSM---MGVLQLLHIFWAYLILRMAHKFITGK
280 290 300 310 320 330
320 330 340 350 360 370
pF1KSD REYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
NP_071 LVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND
340 350 360 370 380
370 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:40:02 2016 done: Wed Nov 2 23:40:03 2016
Total Scan time: 6.580 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]