FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0063, 202 aa
1>>>pF1KSDA0063 202 - 202 aa - 202 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9817+/-0.000295; mu= 14.7548+/- 0.018
mean_var=57.5728+/-11.891, 0's: 0 Z-trim(116.7): 20 B-trim: 0 in 0/56
Lambda= 0.169031
statistics sampled from 28055 (28075) to 28055 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.329), width: 16
Scan time: 4.780
The best scores are: opt bits E(85289)
XP_005261934 (OMIM: 615323) PREDICTED: josephin-1 ( 202) 1405 350.3 1.2e-96
XP_005261933 (OMIM: 615323) PREDICTED: josephin-1 ( 202) 1405 350.3 1.2e-96
XP_005261936 (OMIM: 615323) PREDICTED: josephin-1 ( 202) 1405 350.3 1.2e-96
XP_005261935 (OMIM: 615323) PREDICTED: josephin-1 ( 202) 1405 350.3 1.2e-96
NP_055691 (OMIM: 615323) josephin-1 [Homo sapiens] ( 202) 1405 350.3 1.2e-96
NP_001257568 (OMIM: 615324) josephin-2 isoform 1 [ ( 188) 677 172.8 3.1e-43
NP_001257569 (OMIM: 615324) josephin-2 isoform 1 [ ( 188) 677 172.8 3.1e-43
NP_612207 (OMIM: 615324) josephin-2 isoform 1 [Hom ( 188) 677 172.8 3.1e-43
XP_011524736 (OMIM: 615324) PREDICTED: josephin-2 ( 188) 677 172.8 3.1e-43
NP_001257615 (OMIM: 615324) josephin-2 isoform 1 [ ( 188) 677 172.8 3.1e-43
NP_001257570 (OMIM: 615324) josephin-2 isoform 2 [ ( 146) 331 88.3 6.4e-18
NP_004984 (OMIM: 109150,607047) ataxin-3 reference ( 361) 134 40.5 0.004
>>XP_005261934 (OMIM: 615323) PREDICTED: josephin-1 isof (202 aa)
initn: 1405 init1: 1405 opt: 1405 Z-score: 1856.1 bits: 350.3 E(85289): 1.2e-96
Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
130 140 150 160 170 180
190 200
pF1KSD NCELLLVVPEEVEAHQSWRTDV
::::::::::::::::::::::
XP_005 NCELLLVVPEEVEAHQSWRTDV
190 200
>>XP_005261933 (OMIM: 615323) PREDICTED: josephin-1 isof (202 aa)
initn: 1405 init1: 1405 opt: 1405 Z-score: 1856.1 bits: 350.3 E(85289): 1.2e-96
Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
130 140 150 160 170 180
190 200
pF1KSD NCELLLVVPEEVEAHQSWRTDV
::::::::::::::::::::::
XP_005 NCELLLVVPEEVEAHQSWRTDV
190 200
>>XP_005261936 (OMIM: 615323) PREDICTED: josephin-1 isof (202 aa)
initn: 1405 init1: 1405 opt: 1405 Z-score: 1856.1 bits: 350.3 E(85289): 1.2e-96
Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
130 140 150 160 170 180
190 200
pF1KSD NCELLLVVPEEVEAHQSWRTDV
::::::::::::::::::::::
XP_005 NCELLLVVPEEVEAHQSWRTDV
190 200
>>XP_005261935 (OMIM: 615323) PREDICTED: josephin-1 isof (202 aa)
initn: 1405 init1: 1405 opt: 1405 Z-score: 1856.1 bits: 350.3 E(85289): 1.2e-96
Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
130 140 150 160 170 180
190 200
pF1KSD NCELLLVVPEEVEAHQSWRTDV
::::::::::::::::::::::
XP_005 NCELLLVVPEEVEAHQSWRTDV
190 200
>>NP_055691 (OMIM: 615323) josephin-1 [Homo sapiens] (202 aa)
initn: 1405 init1: 1405 opt: 1405 Z-score: 1856.1 bits: 350.3 E(85289): 1.2e-96
Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
130 140 150 160 170 180
190 200
pF1KSD NCELLLVVPEEVEAHQSWRTDV
::::::::::::::::::::::
NP_055 NCELLLVVPEEVEAHQSWRTDV
190 200
>>NP_001257568 (OMIM: 615324) josephin-2 isoform 1 [Homo (188 aa)
initn: 613 init1: 482 opt: 677 Z-score: 897.1 bits: 172.8 E(85289): 3.1e-43
Smith-Waterman score: 677; 55.2% identity (79.2% similar) in 183 aa overlap (20-201:8-188)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
: .:: .:::.:: ::::.::::::.:.. :.... .::
NP_001 MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQ-LFSQEAADEIC
10 20 30 40
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
.::.:.. ..::. :.::.::::::::::::: : :::::.:: .. .:: .:.:.:.
NP_001 KRLAPDSRLNPHR-SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
:::: . : :.:::.:.::. .:.: :.::::::::. :: .: :. .: :: :
NP_001 NLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQG
110 120 130 140 150 160
190 200
pF1KSD NCELLLVVPEEVEAHQSW-RTDV
::.:::: .::: . :: :::
NP_001 LCEVLLVVTKEVEEKGSWLRTD
170 180
>>NP_001257569 (OMIM: 615324) josephin-2 isoform 1 [Homo (188 aa)
initn: 613 init1: 482 opt: 677 Z-score: 897.1 bits: 172.8 E(85289): 3.1e-43
Smith-Waterman score: 677; 55.2% identity (79.2% similar) in 183 aa overlap (20-201:8-188)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
: .:: .:::.:: ::::.::::::.:.. :.... .::
NP_001 MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQ-LFSQEAADEIC
10 20 30 40
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
.::.:.. ..::. :.::.::::::::::::: : :::::.:: .. .:: .:.:.:.
NP_001 KRLAPDSRLNPHR-SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
:::: . : :.:::.:.::. .:.: :.::::::::. :: .: :. .: :: :
NP_001 NLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQG
110 120 130 140 150 160
190 200
pF1KSD NCELLLVVPEEVEAHQSW-RTDV
::.:::: .::: . :: :::
NP_001 LCEVLLVVTKEVEEKGSWLRTD
170 180
>>NP_612207 (OMIM: 615324) josephin-2 isoform 1 [Homo sa (188 aa)
initn: 613 init1: 482 opt: 677 Z-score: 897.1 bits: 172.8 E(85289): 3.1e-43
Smith-Waterman score: 677; 55.2% identity (79.2% similar) in 183 aa overlap (20-201:8-188)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
: .:: .:::.:: ::::.::::::.:.. :.... .::
NP_612 MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQ-LFSQEAADEIC
10 20 30 40
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
.::.:.. ..::. :.::.::::::::::::: : :::::.:: .. .:: .:.:.:.
NP_612 KRLAPDSRLNPHR-SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
:::: . : :.:::.:.::. .:.: :.::::::::. :: .: :. .: :: :
NP_612 NLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQG
110 120 130 140 150 160
190 200
pF1KSD NCELLLVVPEEVEAHQSW-RTDV
::.:::: .::: . :: :::
NP_612 LCEVLLVVTKEVEEKGSWLRTD
170 180
>>XP_011524736 (OMIM: 615324) PREDICTED: josephin-2 isof (188 aa)
initn: 613 init1: 482 opt: 677 Z-score: 897.1 bits: 172.8 E(85289): 3.1e-43
Smith-Waterman score: 677; 55.2% identity (79.2% similar) in 183 aa overlap (20-201:8-188)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
: .:: .:::.:: ::::.::::::.:.. :.... .::
XP_011 MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQ-LFSQEAADEIC
10 20 30 40
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
.::.:.. ..::. :.::.::::::::::::: : :::::.:: .. .:: .:.:.:.
XP_011 KRLAPDSRLNPHR-SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
:::: . : :.:::.:.::. .:.: :.::::::::. :: .: :. .: :: :
XP_011 NLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQG
110 120 130 140 150 160
190 200
pF1KSD NCELLLVVPEEVEAHQSW-RTDV
::.:::: .::: . :: :::
XP_011 LCEVLLVVTKEVEEKGSWLRTD
170 180
>>NP_001257615 (OMIM: 615324) josephin-2 isoform 1 [Homo (188 aa)
initn: 613 init1: 482 opt: 677 Z-score: 897.1 bits: 172.8 E(85289): 3.1e-43
Smith-Waterman score: 677; 55.2% identity (79.2% similar) in 183 aa overlap (20-201:8-188)
10 20 30 40 50 60
pF1KSD MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIF
: .:: .:::.:: ::::.::::::.:.. :.... .::
NP_001 MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQ-LFSQEAADEIC
10 20 30 40
70 80 90 100 110 120
pF1KSD QRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIM
.::.:.. ..::. :.::.::::::::::::: : :::::.:: .. .:: .:.:.:.
NP_001 KRLAPDSRLNPHR-SLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD NLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGK
:::: . : :.:::.:.::. .:.: :.::::::::. :: .: :. .: :: :
NP_001 NLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQG
110 120 130 140 150 160
190 200
pF1KSD NCELLLVVPEEVEAHQSW-RTDV
::.:::: .::: . :: :::
NP_001 LCEVLLVVTKEVEEKGSWLRTD
170 180
202 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:41:44 2016 done: Wed Nov 2 23:41:44 2016
Total Scan time: 4.780 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]