Result of FASTA (omim) for
pF1KSDA0064
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0064, 470 aa
1>>>pF1KSDA0064 470 - 470 aa - 470 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7208+/-0.000352; mu= 16.1155+/- 0.022
mean_var=79.7522+/-15.959, 0's: 0 Z-trim(114.9): 48 B-trim: 424 in 2/56
Lambda= 0.143616
statistics sampled from 24928 (24975) to 24928 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.293), width: 16
Scan time: 7.580
The best scores are: opt bits E(85289)
NP_055563 (OMIM: 605963) sorting nexin-17 isoform ( 470) 3046 640.8 2.3e-183
NP_001253990 (OMIM: 605963) sorting nexin-17 isofo ( 450) 2908 612.2 9e-175
NP_001253988 (OMIM: 605963) sorting nexin-17 isofo ( 458) 2747 578.9 1e-164
NP_001253989 (OMIM: 605963) sorting nexin-17 isofo ( 445) 2734 576.2 6.4e-164
XP_011531505 (OMIM: 605963) PREDICTED: sorting nex ( 256) 1667 355.0 1.4e-97
XP_016860894 (OMIM: 605963) PREDICTED: sorting nex ( 256) 1667 355.0 1.4e-97
XP_005245567 (OMIM: 611541) PREDICTED: sorting nex ( 438) 406 93.8 1e-18
NP_112180 (OMIM: 611541) sorting nexin-27 isoform ( 528) 406 93.9 1.2e-18
NP_001317652 (OMIM: 611541) sorting nexin-27 isofo ( 541) 406 93.9 1.2e-18
XP_016857906 (OMIM: 611541) PREDICTED: sorting nex ( 407) 390 90.5 9.4e-18
XP_011508327 (OMIM: 611541) PREDICTED: sorting nex ( 420) 390 90.5 9.6e-18
XP_011508326 (OMIM: 611541) PREDICTED: sorting nex ( 440) 388 90.1 1.3e-17
XP_005245568 (OMIM: 611541) PREDICTED: sorting nex ( 342) 367 85.7 2.2e-16
XP_011508328 (OMIM: 611541) PREDICTED: sorting nex ( 419) 321 76.2 1.9e-13
>>NP_055563 (OMIM: 605963) sorting nexin-17 isoform 1 [H (470 aa)
initn: 3046 init1: 3046 opt: 3046 Z-score: 3412.9 bits: 640.8 E(85289): 2.3e-183
Smith-Waterman score: 3046; 100.0% identity (100.0% similar) in 470 aa overlap (1-470:1-470)
10 20 30 40 50 60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
370 380 390 400 410 420
430 440 450 460 470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
430 440 450 460 470
>>NP_001253990 (OMIM: 605963) sorting nexin-17 isoform 4 (450 aa)
initn: 2908 init1: 2908 opt: 2908 Z-score: 3258.7 bits: 612.2 E(85289): 9e-175
Smith-Waterman score: 2908; 99.8% identity (100.0% similar) in 450 aa overlap (21-470:1-450)
10 20 30 40 50 60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
.:::::::::::::::::::::::::::::::::::::::
NP_001 MAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
10 20 30 40
70 80 90 100 110 120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
350 360 370 380 390 400
430 440 450 460 470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
410 420 430 440 450
>>NP_001253988 (OMIM: 605963) sorting nexin-17 isoform 2 (458 aa)
initn: 2747 init1: 2747 opt: 2747 Z-score: 3078.3 bits: 578.9 E(85289): 1e-164
Smith-Waterman score: 2934; 97.4% identity (97.4% similar) in 470 aa overlap (1-470:1-458)
10 20 30 40 50 60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
:::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCR------------LRKEYGANVLPAFP
10 20 30 40
70 80 90 100 110 120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
350 360 370 380 390 400
430 440 450 460 470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
410 420 430 440 450
>>NP_001253989 (OMIM: 605963) sorting nexin-17 isoform 3 (445 aa)
initn: 2859 init1: 2734 opt: 2734 Z-score: 3063.9 bits: 576.2 E(85289): 6.4e-164
Smith-Waterman score: 2813; 94.7% identity (94.7% similar) in 470 aa overlap (1-470:1-445)
10 20 30 40 50 60
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP
::::::::::::::::::::: ::::::::::::::
NP_001 MHFSIPETESRSGDSGGSAYV-------------------------LRKEYGANVLPAFP
10 20 30
70 80 90 100 110 120
pF1KSD PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLE
340 350 360 370 380 390
430 440 450 460 470
pF1KSD SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
400 410 420 430 440
>>XP_011531505 (OMIM: 605963) PREDICTED: sorting nexin-1 (256 aa)
initn: 1667 init1: 1667 opt: 1667 Z-score: 1872.7 bits: 355.0 E(85289): 1.4e-97
Smith-Waterman score: 1667; 100.0% identity (100.0% similar) in 256 aa overlap (215-470:1-256)
190 200 210 220 230 240
pF1KSD PYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVTKEQH
::::::::::::::::::::::::::::::
XP_011 MENRVGLNLLYAQTVSDIERGWILVTKEQH
10 20 30
250 260 270 280 290 300
pF1KSD RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
40 50 60 70 80 90
310 320 330 340 350 360
pF1KSD GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
100 110 120 130 140 150
370 380 390 400 410 420
pF1KSD TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
160 170 180 190 200 210
430 440 450 460 470
pF1KSD TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
220 230 240 250
>>XP_016860894 (OMIM: 605963) PREDICTED: sorting nexin-1 (256 aa)
initn: 1667 init1: 1667 opt: 1667 Z-score: 1872.7 bits: 355.0 E(85289): 1.4e-97
Smith-Waterman score: 1667; 100.0% identity (100.0% similar) in 256 aa overlap (215-470:1-256)
190 200 210 220 230 240
pF1KSD PYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVTKEQH
::::::::::::::::::::::::::::::
XP_016 MENRVGLNLLYAQTVSDIERGWILVTKEQH
10 20 30
250 260 270 280 290 300
pF1KSD RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLP
40 50 60 70 80 90
310 320 330 340 350 360
pF1KSD GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTI
100 110 120 130 140 150
370 380 390 400 410 420
pF1KSD TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDA
160 170 180 190 200 210
430 440 450 460 470
pF1KSD TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
220 230 240 250
>>XP_005245567 (OMIM: 611541) PREDICTED: sorting nexin-2 (438 aa)
initn: 269 init1: 174 opt: 406 Z-score: 457.2 bits: 93.8 E(85289): 1e-18
Smith-Waterman score: 438; 25.8% identity (57.9% similar) in 399 aa overlap (4-397:63-430)
10 20 30
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHC
:.:. . ...: .:.::... : :
XP_005 PPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPR--YKHVEQNGEKFVVYNVYMAGRQLC
40 50 60 70 80 90
40 50 60 70 80 90
pF1KSD RVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLG
:: .. ::..:..:.. ..: .: : :::. ... ::. ::.:.. : . ..:
XP_005 SKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIG
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD SSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLP
:. .. :: ..... . : .: :.: : .: : : : .. :..: .:.:::. .
XP_005 ESDIMQEFLSESDENYNGVS--DVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMD
160 170 180 190 200
160 170 180 190 200 210
pF1KSD DDLIGYFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDD
. ..::.:: : . :::::: :.:. . . . : : : . ..
XP_005 STTVNYFALF-----EVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEE
210 220 230 240 250 260
220 230 240 250 260 270
pF1KSD DVM--ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYG
... .: .... .. :.:.:...:.: . .:. ::..: :. . .: . .: . :.
XP_005 EILLNDNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYN
270 280 290 300 310 320
280 290 300 310 320
pF1KSD YLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVP
. : :. : .: :... . ....:. ::.. .:. .:. :
XP_005 EIIFPHCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-------
330 340 350 360 370
330 340 350 360 370 380
pF1KSD LPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKS
.:. : . . ::: .. . .:: : .: .: :.. . :: .:
XP_005 ----DTDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKE
380 390 400 410 420
390 400 410 420 430 440
pF1KSD GGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPS
.: .: :
XP_005 --NIFQMARSQQRDVAT
430
>>NP_112180 (OMIM: 611541) sorting nexin-27 isoform 2 [H (528 aa)
initn: 269 init1: 174 opt: 406 Z-score: 456.0 bits: 93.9 E(85289): 1.2e-18
Smith-Waterman score: 436; 25.7% identity (58.1% similar) in 389 aa overlap (4-387:166-525)
10 20 30
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHC
:.:. . ...: .:.::... : :
NP_112 PPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPR--YKHVEQNGEKFVVYNVYMAGRQLC
140 150 160 170 180 190
40 50 60 70 80 90
pF1KSD RVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLG
:: .. ::..:..:.. ..: .: : :::. ... ::. ::.:.. : . ..:
NP_112 SKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIG
200 210 220 230 240 250
100 110 120 130 140 150
pF1KSD SSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLP
:. .. :: ..... . : .: :.: : .: : : : .. :..: .:.:::. .
NP_112 ESDIMQEFLSESDENYNGV--SDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMD
260 270 280 290 300 310
160 170 180 190 200 210
pF1KSD DDLIGYFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDD
. ..::.:: : . :::::: :.:. . . . : : : . ..
NP_112 STTVNYFALFEVI-----SHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEE
320 330 340 350 360
220 230 240 250 260 270
pF1KSD DVM--ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYG
... .: .... .. :.:.:...:.: . .:. ::..: :. . .: . .: . :.
NP_112 EILLNDNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYN
370 380 390 400 410 420
280 290 300 310 320
pF1KSD YLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVP
. : :. : .: :... . ....:. ::.. .:. .:. :
NP_112 EIIFPHCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-------
430 440 450 460 470
330 340 350 360 370 380
pF1KSD LPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKS
.:. : . . ::: .. . .:: : .: .: :.. . :: .:
NP_112 ----DTDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKE
480 490 500 510 520
390 400 410 420 430 440
pF1KSD GGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPS
NP_112 EY
>>NP_001317652 (OMIM: 611541) sorting nexin-27 isoform 1 (541 aa)
initn: 269 init1: 174 opt: 406 Z-score: 455.8 bits: 93.9 E(85289): 1.2e-18
Smith-Waterman score: 438; 25.8% identity (57.9% similar) in 399 aa overlap (4-397:166-533)
10 20 30
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHC
:.:. . ...: .:.::... : :
NP_001 PPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPR--YKHVEQNGEKFVVYNVYMAGRQLC
140 150 160 170 180 190
40 50 60 70 80 90
pF1KSD RVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLG
:: .. ::..:..:.. ..: .: : :::. ... ::. ::.:.. : . ..:
NP_001 SKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIG
200 210 220 230 240 250
100 110 120 130 140 150
pF1KSD SSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLP
:. .. :: ..... . : .: :.: : .: : : : .. :..: .:.:::. .
NP_001 ESDIMQEFLSESDENYNGVS--DVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMD
260 270 280 290 300 310
160 170 180 190 200 210
pF1KSD DDLIGYFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDD
. ..::.:: : . :::::: :.:. . . . : : : . ..
NP_001 STTVNYFALF-----EVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEE
320 330 340 350 360
220 230 240 250 260 270
pF1KSD DVM--ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYG
... .: .... .. :.:.:...:.: . .:. ::..: :. . .: . .: . :.
NP_001 EILLNDNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYN
370 380 390 400 410 420
280 290 300 310 320
pF1KSD YLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVP
. : :. : .: :... . ....:. ::.. .:. .:. :
NP_001 EIIFPHCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-------
430 440 450 460 470
330 340 350 360 370 380
pF1KSD LPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKS
.:. : . . ::: .. . .:: : .: .: :.. . :: .:
NP_001 ----DTDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKE
480 490 500 510 520
390 400 410 420 430 440
pF1KSD GGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPS
.: .: :
NP_001 --NIFQMARSQQRDVAT
530 540
>>XP_016857906 (OMIM: 611541) PREDICTED: sorting nexin-2 (407 aa)
initn: 291 init1: 174 opt: 390 Z-score: 439.7 bits: 90.5 E(85289): 9.4e-18
Smith-Waterman score: 420; 25.8% identity (57.8% similar) in 384 aa overlap (9-387:48-404)
10 20 30
pF1KSD MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYS
.:.:: . . .::... : : ::
XP_016 GGGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVYNVYMAGRQLCSKRYR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KSD QLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETF
.. ::..:..:.. ..: .: : :::. ... ::. ::.:.. : . ..: :. .
XP_016 EFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIM
80 90 100 110 120 130
100 110 120 130 140 150
pF1KSD NSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIG
. :: ..... . : .: :.: : .: : : : .. :..: .:.:::. . . ..
XP_016 QEFLSESDENYNGVS--DVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KSD YFSLFLVREKEDGAFSFVRKLQEFELPY-VSVTSLRSQEYKIVLRKSYWDSAYDDDVM--
::.:: : . :::::: :.:. . . . : : : . .....
XP_016 YFALFEVI-----SHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLN
200 210 220 230 240 250
220 230 240 250 260 270
pF1KSD ENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFD
.: .... .. :.:.:...:.: . .:. ::..: :. . .: . .: . :. . :
XP_016 DNDLAVTYFFHQAVDDVKKGYIKA-EEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFP
260 270 280 290 300
280 290 300 310 320 330
pF1KSD ACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREG--SFRVTRMRCWRVTSSVPLPSGS
:. : .: :... . ....:. ::.. .:. .:. : .
XP_016 HCACDSRRKG-HVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW-----------D
310 320 330 340 350
340 350 360 370 380 390
pF1KSD TSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKSGGSIR
:. : . . ::: .. . .:: : .: .: :.. . :: .:
XP_016 TDEEG-------MAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKEEY
360 370 380 390 400
400 410 420 430 440 450
pF1KSD KMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPSTDASA
470 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:42:14 2016 done: Wed Nov 2 23:42:15 2016
Total Scan time: 7.580 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]