Result of FASTA (omim) for pF1KSDA0067
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0067, 1291 aa
  1>>>pF1KSDA0067 1291 - 1291 aa - 1291 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.3932+/-0.000439; mu= -9.5760+/- 0.027
 mean_var=378.8531+/-78.839, 0's: 0 Z-trim(121.4): 52  B-trim: 1893 in 2/56
 Lambda= 0.065893
 statistics sampled from 37876 (37936) to 37876 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.445), width:  16
 Scan time: 16.390

The best scores are:                                      opt bits E(85289)
NP_001138887 (OMIM: 604396) histone-lysine N-methy (1291) 8782 850.0       0
XP_005245698 (OMIM: 604396) PREDICTED: histone-lys (1292) 8764 848.3       0
XP_016858442 (OMIM: 604396) PREDICTED: histone-lys (1292) 8764 848.3       0
NP_036564 (OMIM: 604396) histone-lysine N-methyltr (1290) 8763 848.2       0
XP_016858443 (OMIM: 604396) PREDICTED: histone-lys ( 739) 4983 488.7 6.3e-137
XP_016858444 (OMIM: 604396) PREDICTED: histone-lys ( 397) 2495 252.0   6e-66
NP_001230420 (OMIM: 604396) histone-lysine N-methy ( 397) 2495 252.0   6e-66
NP_001153780 (OMIM: 607865) histone-lysine N-methy ( 707)  857 96.5 7.2e-19
NP_001307628 (OMIM: 607865) histone-lysine N-methy ( 707)  857 96.5 7.2e-19
NP_114121 (OMIM: 607865) histone-lysine N-methyltr ( 719)  857 96.5 7.3e-19


>>NP_001138887 (OMIM: 604396) histone-lysine N-methyltra  (1291 aa)
 initn: 8782 init1: 8782 opt: 8782  Z-score: 4527.5  bits: 850.0 E(85289):    0
Smith-Waterman score: 8782; 100.0% identity (100.0% similar) in 1291 aa overlap (1-1291:1-1291)

               10        20        30        40        50        60
pF1KSD MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD AQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRME
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD AEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD SMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD EGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQF
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD YDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTE
             1210      1220      1230      1240      1250      1260

             1270      1280      1290 
pF1KSD LTWDYNYEVGSVEGKELLCCCGAIECRGRLL
       :::::::::::::::::::::::::::::::
NP_001 LTWDYNYEVGSVEGKELLCCCGAIECRGRLL
             1270      1280      1290 

>>XP_005245698 (OMIM: 604396) PREDICTED: histone-lysine   (1292 aa)
 initn: 8762 init1: 5619 opt: 8764  Z-score: 4518.3  bits: 848.3 E(85289):    0
Smith-Waterman score: 8764; 99.8% identity (99.9% similar) in 1292 aa overlap (1-1291:1-1292)

               10        20        30        40        50        60
pF1KSD MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
              370       380       390       400       410       420

              430       440       450       460       470          
pF1KSD NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSD-LESQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::. ::::
XP_005 NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSESLESQ
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD LAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAP
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD SALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNP
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD LLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFC
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KSD LDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFI
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KSD NTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVY
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KSD ECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTD
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KSD DFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPE
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KSD ESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPV
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KSD PPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRM
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KSD EAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSK
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KSD TSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSG
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KSD SEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQ
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KSD FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290 
pF1KSD ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
       ::::::::::::::::::::::::::::::::
XP_005 ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
             1270      1280      1290  

>>XP_016858442 (OMIM: 604396) PREDICTED: histone-lysine   (1292 aa)
 initn: 8762 init1: 5619 opt: 8764  Z-score: 4518.3  bits: 848.3 E(85289):    0
Smith-Waterman score: 8764; 99.8% identity (99.9% similar) in 1292 aa overlap (1-1291:1-1292)

               10        20        30        40        50        60
pF1KSD MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
              370       380       390       400       410       420

              430       440       450       460       470          
pF1KSD NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSD-LESQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::. ::::
XP_016 NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSESLESQ
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD LAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAP
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD SALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNP
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD LLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFC
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KSD LDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFI
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KSD NTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVY
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KSD ECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTD
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KSD DFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPE
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KSD ESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPV
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KSD PPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRM
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KSD EAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSK
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KSD TSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSG
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KSD SEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQ
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KSD FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290 
pF1KSD ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
       ::::::::::::::::::::::::::::::::
XP_016 ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
             1270      1280      1290  

>>NP_036564 (OMIM: 604396) histone-lysine N-methyltransf  (1290 aa)
 initn: 8510 init1: 8510 opt: 8763  Z-score: 4517.8  bits: 848.2 E(85289):    0
Smith-Waterman score: 8763; 99.9% identity (99.9% similar) in 1291 aa overlap (1-1291:1-1290)

               10        20        30        40        50        60
pF1KSD MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD AQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRME
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD AEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD SMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD EGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQF
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD YDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_036 YDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTE
             1210      1220      1230      1240      1250          

             1270      1280      1290 
pF1KSD LTWDYNYEVGSVEGKELLCCCGAIECRGRLL
       :::::::::::::::::::::::::::::::
NP_036 LTWDYNYEVGSVEGKELLCCCGAIECRGRLL
    1260      1270      1280      1290

>>XP_016858443 (OMIM: 604396) PREDICTED: histone-lysine   (739 aa)
 initn: 4981 init1: 3157 opt: 4983  Z-score: 2579.3  bits: 488.7 E(85289): 6.3e-137
Smith-Waterman score: 4983; 99.7% identity (99.9% similar) in 739 aa overlap (1-738:1-739)

               10        20        30        40        50        60
pF1KSD MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
              370       380       390       400       410       420

              430       440       450       460       470          
pF1KSD NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSD-LESQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::. ::::
XP_016 NMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSESLESQ
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD LAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAP
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD SALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNP
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD LLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFC
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KSD LDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFI
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KSD NTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVY
       :::::::::::::::::::                                         
XP_016 NTGPEFLVGCDCKDGCRDK                                         
              730                                                  

>>XP_016858444 (OMIM: 604396) PREDICTED: histone-lysine   (397 aa)
 initn: 2495 init1: 2495 opt: 2495  Z-score: 1305.0  bits: 252.0 E(85289): 6e-66
Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)

               10        20        30        40        50        60
pF1KSD MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
       ::::::::::::::::::::                                        
XP_016 TWWKSRVEEVDGSLVRILFLVLFFSTILEAEVGGGGT                       
              370       380       390                              

>>NP_001230420 (OMIM: 604396) histone-lysine N-methyltra  (397 aa)
 initn: 2495 init1: 2495 opt: 2495  Z-score: 1305.0  bits: 252.0 E(85289): 6e-66
Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)

               10        20        30        40        50        60
pF1KSD MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRP
       ::::::::::::::::::::                                        
NP_001 TWWKSRVEEVDGSLVRILFLVLFFSTILEAEVGGGGT                       
              370       380       390                              

>>NP_001153780 (OMIM: 607865) histone-lysine N-methyltra  (707 aa)
 initn: 1181 init1: 764 opt: 857  Z-score: 459.8  bits: 96.5 E(85289): 7.2e-19
Smith-Waterman score: 1038; 31.4% identity (55.3% similar) in 722 aa overlap (571-1291:128-707)

              550       560       570       580       590       600
pF1KSD ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
                                     : :  : :: .:: .. :.   . .:.:::
NP_001 DCTFLTTENKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
       100       110       120       130       140           150   

              610       620       630       640       650       660
pF1KSD LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
        .:.   :.:  :.   ... ..:: ::::::  ::...:. :::.:: :.::: . : .
NP_001 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
           160        170       180       190       200       210  

              670       680       690       700       710       720
pF1KSD DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
       . :: . :..   :     .::. : :.::.:  ::::.   ::  : :   :    . :
NP_001 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
            220       230       240       250       260       270  

              730       740       750       760       770       780
pF1KSD TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
        .  :  .:::..:: : .:::: ::: . .  .: .. . ..::.::::.. .:::.::
NP_001 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
            280       290       300       310       320       330  

              790       800       810       820       830       840
pF1KSD CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
       :.  :::. ..: ::.:::: :::::.:::..::::.:::::: .:.:::::.:..:.  
NP_001 CSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSR-
            340       350       360       370       380       390  

              850       860       870       880       890       900
pF1KSD FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
        :. :     ::   . . ....  :..  . .. ::.                      
NP_001 -ANTEKSYGIDENGRDENTMKNI--FSKKRKLEVACSD----------------------
              400       410         420                            

              910       920       930       940       950       960
pF1KSD SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
                 :. : .                     ::      ..::      . :  
NP_001 ----------CEVEVLPL-------------------GL------ETHPRTAKTEKCP--
                  430                                440           

              970       980       990      1000       1010         
pF1KSD PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSS-FKTNEGGEGRAGGSRM
          :  . ::       :    : .. .::    . : .:... :. :        :..:
NP_001 ---PKFSNNPKELTVETKYDNISRIQYHSV----IRDPESKTAIFQHN--------GKKM
        450       460       470           480       490            

    1020      1030      1040      1050      1060      1070         
pF1KSD EAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSK
       :   .:. ..  .:.  .:  . :  ....: ..  .:: :.                  
NP_001 EF--VSSESVTPEDNDGFKPPR-EHLNSKTK-GAQKDSSSNH------------------
            500       510        520        530                    

    1080      1090      1100      1110      1120      1130         
pF1KSD TSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSG
       ..  ..  :. :      ::. ...  :   :.     : .  ..::..:...:.     
NP_001 VDEFEDNLLIES------DVIDITKYRE---ET----PPRSRCNQATTLDNQNIK-----
            540             550              560       570         

    1140      1150      1160      1170      1180      1190         
pF1KSD SEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQ
        .. . . .: . :   :..: .  . :           . .. :  :. :.    .  .
NP_001 -KAIEVQIQKPQEG---RSTACQRQQVFC----------DEELLSETKNTSSD---SLTK
           580          590                 600       610          

    1200      1210      1220      1230      1240      1250         
pF1KSD FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
       :  :  . ...::  :::.::.::::: :::.::::::.::.  :: ::::... ..: :
NP_001 FNKG--NVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKART
       620         630       640       650       660       670     

    1260      1270      1280      1290 
pF1KSD ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
       ::::::.::.:.:  ::..: ::. .:: ..:
NP_001 ELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
         680       690       700       

>>NP_001307628 (OMIM: 607865) histone-lysine N-methyltra  (707 aa)
 initn: 1181 init1: 764 opt: 857  Z-score: 459.8  bits: 96.5 E(85289): 7.2e-19
Smith-Waterman score: 1038; 31.4% identity (55.3% similar) in 722 aa overlap (571-1291:128-707)

              550       560       570       580       590       600
pF1KSD ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
                                     : :  : :: .:: .. :.   . .:.:::
NP_001 DCTFLTTENKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
       100       110       120       130       140           150   

              610       620       630       640       650       660
pF1KSD LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
        .:.   :.:  :.   ... ..:: ::::::  ::...:. :::.:: :.::: . : .
NP_001 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
           160        170       180       190       200       210  

              670       680       690       700       710       720
pF1KSD DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
       . :: . :..   :     .::. : :.::.:  ::::.   ::  : :   :    . :
NP_001 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
            220       230       240       250       260       270  

              730       740       750       760       770       780
pF1KSD TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
        .  :  .:::..:: : .:::: ::: . .  .: .. . ..::.::::.. .:::.::
NP_001 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
            280       290       300       310       320       330  

              790       800       810       820       830       840
pF1KSD CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
       :.  :::. ..: ::.:::: :::::.:::..::::.:::::: .:.:::::.:..:.  
NP_001 CSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSR-
            340       350       360       370       380       390  

              850       860       870       880       890       900
pF1KSD FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
        :. :     ::   . . ....  :..  . .. ::.                      
NP_001 -ANTEKSYGIDENGRDENTMKNI--FSKKRKLEVACSD----------------------
              400       410         420                            

              910       920       930       940       950       960
pF1KSD SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
                 :. : .                     ::      ..::      . :  
NP_001 ----------CEVEVLPL-------------------GL------ETHPRTAKTEKCP--
                  430                                440           

              970       980       990      1000       1010         
pF1KSD PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSS-FKTNEGGEGRAGGSRM
          :  . ::       :    : .. .::    . : .:... :. :        :..:
NP_001 ---PKFSNNPKELTVETKYDNISRIQYHSV----IRDPESKTAIFQHN--------GKKM
        450       460       470           480       490            

    1020      1030      1040      1050      1060      1070         
pF1KSD EAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSK
       :   .:. ..  .:.  .:  . :  ....: ..  .:: :.                  
NP_001 EF--VSSESVTPEDNDGFKPPR-EHLNSKTK-GAQKDSSSNH------------------
            500       510        520        530                    

    1080      1090      1100      1110      1120      1130         
pF1KSD TSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSG
       ..  ..  :. :      ::. ...  :   :.     : .  ..::..:...:.     
NP_001 VDEFEDNLLIES------DVIDITKYRE---ET----PPRSRCNQATTLDNQNIK-----
            540             550              560       570         

    1140      1150      1160      1170      1180      1190         
pF1KSD SEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQ
        .. . . .: . :   :..: .  . :           . .. :  :. :.    .  .
NP_001 -KAIEVQIQKPQEG---RSTACQRQQVFC----------DEELLSETKNTSSD---SLTK
           580          590                 600       610          

    1200      1210      1220      1230      1240      1250         
pF1KSD FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
       :  :  . ...::  :::.::.::::: :::.::::::.::.  :: ::::... ..: :
NP_001 FNKG--NVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKART
       620         630       640       650       660       670     

    1260      1270      1280      1290 
pF1KSD ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
       ::::::.::.:.:  ::..: ::. .:: ..:
NP_001 ELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
         680       690       700       

>>NP_114121 (OMIM: 607865) histone-lysine N-methyltransf  (719 aa)
 initn: 1181 init1: 764 opt: 857  Z-score: 459.7  bits: 96.5 E(85289): 7.3e-19
Smith-Waterman score: 1038; 31.4% identity (55.3% similar) in 722 aa overlap (571-1291:140-719)

              550       560       570       580       590       600
pF1KSD ALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPL
                                     : :  : :: .:: .. :.   . .:.:::
NP_114 DCTFLTTENKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKM-PL---NLKGENPL
     110       120       130       140       150           160     

              610       620       630       640       650       660
pF1KSD LVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCL
        .:.   :.:  :.   ... ..:: ::::::  ::...:. :::.:: :.::: . : .
NP_114 QLPIKCHFQRRHAKTN-SHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSF
         170       180        190       200       210       220    

              670       680       690       700       710       720
pF1KSD DPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFIN
       . :: . :..   :     .::. : :.::.:  ::::.   ::  : :   :    . :
NP_114 NTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTN
          230       240       250       260       270       280    

              730       740       750       760       770       780
pF1KSD TGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYE
        .  :  .:::..:: : .:::: ::: . .  .: .. . ..::.::::.. .:::.::
NP_114 FSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYE
          290       300       310       320       330       340    

              790       800       810       820       830       840
pF1KSD CNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDD
       :.  :::. ..: ::.:::: :::::.:::..::::.:::::: .:.:::::.:..:.  
NP_114 CSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSR-
          350       360       370       380       390       400    

              850       860       870       880       890       900
pF1KSD FADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEE
        :. :     ::   . . ....  :..  . .. ::.                      
NP_114 -ANTEKSYGIDENGRDENTMKNI--FSKKRKLEVACSD----------------------
            410       420         430                              

              910       920       930       940       950       960
pF1KSD SNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVP
                 :. : .                     ::      ..::      . :  
NP_114 ----------CEVEVLPL-------------------GL------ETHPRTAKTEKCP--
                440                                450       460   

              970       980       990      1000       1010         
pF1KSD PSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSS-FKTNEGGEGRAGGSRM
          :  . ::       :    : .. .::    . : .:... :. :        :..:
NP_114 ---PKFSNNPKELTVETKYDNISRIQYHSV----IRDPESKTAIFQHN--------GKKM
                470       480           490       500              

    1020      1030      1040      1050      1060      1070         
pF1KSD EAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSK
       :   .:. ..  .:.  .:  . :  ....: ..  .:: :.                  
NP_114 EF--VSSESVTPEDNDGFKPPR-EHLNSKTK-GAQKDSSSNH------------------
          510       520        530        540                      

    1080      1090      1100      1110      1120      1130         
pF1KSD TSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSG
       ..  ..  :. :      ::. ...  :   :.     : .  ..::..:...:.     
NP_114 VDEFEDNLLIES------DVIDITKYRE---ET----PPRSRCNQATTLDNQNIK-----
          550             560              570       580           

    1140      1150      1160      1170      1180      1190         
pF1KSD SEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQ
        .. . . .: . :   :..: .  . :           . .. :  :. :.    .  .
NP_114 -KAIEVQIQKPQEG---RSTACQRQQVFC----------DEELLSETKNTSSD---SLTK
         590          600       610                 620            

    1200      1210      1220      1230      1240      1250         
pF1KSD FYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGT
       :  :  . ...::  :::.::.::::: :::.::::::.::.  :: ::::... ..: :
NP_114 FNKG--NVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKART
     630         640       650       660       670       680       

    1260      1270      1280      1290 
pF1KSD ELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
       ::::::.::.:.:  ::..: ::. .:: ..:
NP_114 ELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
       690       700       710         




1291 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:45:58 2016 done: Wed Nov  2 23:46:00 2016
 Total Scan time: 16.390 Total Display time:  0.370

Function used was FASTA [36.3.4 Apr, 2011]
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