FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0070, 597 aa 1>>>pF1KSDA0070 597 - 597 aa - 597 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8978+/-0.000416; mu= 16.0291+/- 0.026 mean_var=80.5524+/-16.748, 0's: 0 Z-trim(112.5): 31 B-trim: 1086 in 2/48 Lambda= 0.142901 statistics sampled from 21468 (21498) to 21468 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.252), width: 16 Scan time: 8.720 The best scores are: opt bits E(85289) NP_005539 (OMIM: 601421,613641,613916) lysine--tRN ( 597) 3958 826.2 0 NP_001123561 (OMIM: 601421,613641,613916) lysine-- ( 625) 3835 800.8 0 XP_016878706 (OMIM: 601421,613641,613916) PREDICTE ( 441) 2956 619.5 7.1e-177 XP_011508013 (OMIM: 610956,611105) PREDICTED: aspa ( 482) 270 65.8 3.8e-10 XP_006711490 (OMIM: 610956,611105) PREDICTED: aspa ( 594) 270 65.9 4.5e-10 NP_060592 (OMIM: 610956,611105) aspartate--tRNA li ( 645) 270 65.9 4.9e-10 NP_001280241 (OMIM: 603084,615281) aspartate--tRNA ( 401) 153 41.6 0.006 XP_016858978 (OMIM: 603084,615281) PREDICTED: aspa ( 468) 153 41.7 0.0068 NP_001340 (OMIM: 603084,615281) aspartate--tRNA li ( 501) 153 41.7 0.0072 >>NP_005539 (OMIM: 601421,613641,613916) lysine--tRNA li (597 aa) initn: 3958 init1: 3958 opt: 3958 Z-score: 4410.9 bits: 826.2 E(85289): 0 Smith-Waterman score: 3958; 99.8% identity (100.0% similar) in 597 aa overlap (1-597:1-597) 10 20 30 40 50 60 pF1KSD MAAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLSQATAAATNHTT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD MVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYG 490 500 510 520 530 540 550 560 570 580 590 pF1KSD LPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGSSV ::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: NP_005 LPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 550 560 570 580 590 >>NP_001123561 (OMIM: 601421,613641,613916) lysine--tRNA (625 aa) initn: 3835 init1: 3835 opt: 3835 Z-score: 4273.5 bits: 800.8 E(85289): 0 Smith-Waterman score: 3835; 99.5% identity (100.0% similar) in 578 aa overlap (20-597:48-625) 10 20 30 40 pF1KSD MAAVQAAEVKVDGSEPKLSKNELKRRLKAEKKVAEKEAKQKELSEKQLS ..:::::::::::::::::::::::::::: NP_001 SWAEWGHRELRLGQLAPFTAPHKDKSFSDQRSELKRRLKAEKKVAEKEAKQKELSEKQLS 20 30 40 50 60 70 50 60 70 80 90 100 pF1KSD QATAAATNHTTDNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QATAAATNHTTDNGVGPEEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFI 80 90 100 110 120 130 110 120 130 140 150 160 pF1KSD QKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEF 140 150 160 170 180 190 170 180 190 200 210 220 pF1KSD IHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQ 200 210 220 230 240 250 230 240 250 260 270 280 pF1KSD RYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNE 260 270 280 290 300 310 290 300 310 320 330 340 pF1KSD LDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHD 320 330 340 350 360 370 350 360 370 380 390 400 pF1KSD LMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLP 380 390 400 410 420 430 410 420 430 440 450 460 pF1KSD ETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIM 440 450 460 470 480 490 470 480 490 500 510 520 pF1KSD SPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFI 500 510 520 530 540 550 530 540 550 560 570 580 pF1KSD DENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLE 560 570 580 590 600 610 590 pF1KSD STTVGSSV :::::.:: NP_001 STTVGTSV 620 >>XP_016878706 (OMIM: 601421,613641,613916) PREDICTED: l (441 aa) initn: 2956 init1: 2956 opt: 2956 Z-score: 3296.4 bits: 619.5 E(85289): 7.1e-177 Smith-Waterman score: 2956; 99.8% identity (100.0% similar) in 441 aa overlap (157-597:1-441) 130 140 150 160 170 180 pF1KSD KVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQG :::::::::::::::::::::::::::::: XP_016 MANSRNYKSEEEFIHINNKLRRGDIIGVQG 10 20 30 190 200 210 220 230 240 pF1KSD NPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFII 40 50 60 70 80 90 250 260 270 280 290 300 pF1KSD RSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKM 100 110 120 130 140 150 310 320 330 340 350 360 pF1KSD LVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHIT 160 170 180 190 200 210 370 380 390 400 410 420 pF1KSD GSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDI 220 230 240 250 260 270 430 440 450 460 470 480 pF1KSD CVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERF 280 290 300 310 320 330 490 500 510 520 530 540 pF1KSD ELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAG 340 350 360 370 380 390 550 560 570 580 590 pF1KSD WGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGSSV ::::::::::::::::::::::::::::::::::::::::::::::::.:: XP_016 WGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV 400 410 420 430 440 >>XP_011508013 (OMIM: 610956,611105) PREDICTED: aspartat (482 aa) initn: 179 init1: 120 opt: 270 Z-score: 303.1 bits: 65.8 E(85289): 3.8e-10 Smith-Waterman score: 270; 32.4% identity (60.3% similar) in 179 aa overlap (185-358:129-301) 160 170 180 190 200 210 pF1KSD QVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLP : :: : ::. : ::. : . :: XP_011 SAASVKKILCEAPVESVVQVSGTVISRPAGQENP-KMPTGEIEIKVKTAELLNAC-KKLP 100 110 120 130 140 150 220 230 240 250 260 pF1KSD HL--HFGLKDKETRYRQRYLDLILNDFVRQ-KFIIRSKIITYIRSFLDEL-GFLEIETP- .: : . : . :::: : .: : .. .::... .: .: .: ::..:::: XP_011 FEIKNFVKKTEALRLQYRYLD--LRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL ... :::: : :.. : . .:. ....:.:::.:: ....: .:.:: XP_011 LFKRTPGGA--KEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRP 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP ..:::: .. :...: .. . : .. XP_011 DRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDK 280 290 300 310 320 330 >>XP_006711490 (OMIM: 610956,611105) PREDICTED: aspartat (594 aa) initn: 258 init1: 120 opt: 270 Z-score: 301.7 bits: 65.9 E(85289): 4.5e-10 Smith-Waterman score: 346; 26.8% identity (53.7% similar) in 441 aa overlap (185-571:129-554) 160 170 180 190 200 210 pF1KSD QVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLP : :: : ::. : ::. : . :: XP_006 SAASVKKILCEAPVESVVQVSGTVISRPAGQENP-KMPTGEIEIKVKTAELLNAC-KKLP 100 110 120 130 140 150 220 230 240 250 260 pF1KSD HL--HFGLKDKETRYRQRYLDLILNDFVRQ-KFIIRSKIITYIRSFLDEL-GFLEIETP- .: : . : . :::: : .: : .. .::... .: .: .: ::..:::: XP_006 FEIKNFVKKTEALRLQYRYLD--LRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL ... :::: : :.. : . .:. ....:.:::.:: ....: .:.:: XP_006 LFKRTPGGA--KEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRP 220 230 240 250 260 270 330 340 350 360 370 pF1KSD THNPEFTTCEFYMAYADYHDLMEITEKMVSG---------MVKHITGSYK---VTYHPDG ..:::: .. :...: .. . : ... .: : .. .:: : XP_006 DRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDK 280 290 300 310 320 330 380 390 400 410 420 pF1KSD PE---GQAYDVDFTPPFR--RINMVEE-LEKALG----MKLPETNLF----ETEETRKIL :. :. .:.. :: .:..... : : : . .:: . . : :.. XP_006 PDTRFGMKI-IDISDVFRNTEIGFLQDALSKPHGTVKAICIPEGAKYLKRKDIESIRNFA 340 350 360 370 380 390 430 440 450 460 470 pF1KSD DD---IC--VAKA-VECPPPRTT--ARLLDKLVGEFLEVTCINPTFI--CDHPQIMS--- : : ..: .:: : . : : . :: :. . : :. ..:. . XP_006 ADHFNQCSLLGKLRLECADLLETRGVVLRDPTLFSFLWVVDF-PLFLPKEENPRELESAH 400 410 420 430 440 450 480 490 500 510 520 pF1KSD -PLAKWHRS---------KEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKA :.. : : :.. .....: . .:: .. .... :: .. : XP_006 HPFTAPHPSDIHLLYTEPKKARSQHYDLVLNGNEIGGGSIRIHNAELQRYILATLLK--- 460 470 480 490 500 530 540 550 560 570 580 pF1KSD AGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKE .: :. .. ::.:: :: .: ..:.::. ..: : .:..:. :: XP_006 --EDVKML--SHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFPKSFRGHDLM 510 520 530 540 550 560 590 pF1KSD NVATTDTLESTTVGSSV XP_006 SNTPDSVPPEELKPYHIRVSKPTDSKAERAH 570 580 590 >>NP_060592 (OMIM: 610956,611105) aspartate--tRNA ligase (645 aa) initn: 258 init1: 120 opt: 270 Z-score: 301.2 bits: 65.9 E(85289): 4.9e-10 Smith-Waterman score: 270; 32.4% identity (60.3% similar) in 179 aa overlap (185-358:129-301) 160 170 180 190 200 210 pF1KSD QVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLP : :: : ::. : ::. : . :: NP_060 SAASVKKILCEAPVESVVQVSGTVISRPAGQENP-KMPTGEIEIKVKTAELLNAC-KKLP 100 110 120 130 140 150 220 230 240 250 260 pF1KSD HL--HFGLKDKETRYRQRYLDLILNDFVRQ-KFIIRSKIITYIRSFLDEL-GFLEIETP- .: : . : . :::: : .: : .. .::... .: .: .: ::..:::: NP_060 FEIKNFVKKTEALRLQYRYLD--LRSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDL ... :::: : :.. : . .:. ....:.:::.:: ....: .:.:: NP_060 LFKRTPGGA--KEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRP 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP ..:::: .. :...: .. . : .. NP_060 DRQPEFTQIDIEMSFVDQTGIQSLIEGLLQYSWPNDKDPVVVPFPTMTFAEVLATYGTDK 280 290 300 310 320 330 >>NP_001280241 (OMIM: 603084,615281) aspartate--tRNA lig (401 aa) initn: 232 init1: 114 opt: 153 Z-score: 174.0 bits: 41.6 E(85289): 0.006 Smith-Waterman score: 293; 24.6% identity (56.9% similar) in 357 aa overlap (222-571:75-393) 200 210 220 230 240 250 pF1KSD KKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKII ...:: .: .:: .. . : ..: : NP_001 ISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDL-RTSTSQAVFRLQSGIC 50 60 70 80 90 100 260 270 280 290 300 310 pF1KSD TYIRSFLDELGFLEIETP-MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVG .: : . ::.::.:: ... :.. ..: .. : :. .:.::..: . . NP_001 HLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKN---NAYLAQSPQLYKQMCICA 110 120 130 140 150 160 320 330 340 350 360 pF1KSD GIDRVYEIGRQFRNEGIDL-THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSY ...:. :: :: : . : ::. .. ::. .:: :. :.... ::. . : NP_001 DFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAF-NYH-YHEVMEEIADTMVQIFKG-L 170 180 190 200 210 370 380 390 400 410 420 pF1KSD KVTYHPDGPEGQAYDVDFT-PPFRRINMVEELE--KALGMKLPETNLFETEETRKILDDI . .. : :. . .: ::. .. . .:: .::.: : :... .: ::. NP_001 QERFQT---EIQTVNKQFPCEPFKFLEPTLRLEYCEALAM-LREAGVEMGDE-----DDL 220 230 240 250 260 430 440 450 460 470 480 pF1KSD CVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICD-HPQIMSPLAKWHRSKEG-LTE . . .::.:.... . .: : .: . :. .. .. NP_001 STPN--------------EKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSN 270 280 290 300 310 490 500 510 520 530 540 pF1KSD RFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPT ...:. .:: .. ...:: ::. :.: .. : : . . . ....: :: NP_001 SYDMFMRGEEILSGAQRIHDP----QLLTERALHHGI-DLEKI---KAYIDSFRFGAPPH 320 330 340 350 360 550 560 570 580 590 pF1KSD AGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGSSV :: :.:..::.:.. .:.... .:: NP_001 AGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 370 380 390 400 >>XP_016858978 (OMIM: 603084,615281) PREDICTED: aspartat (468 aa) initn: 232 init1: 114 opt: 153 Z-score: 173.0 bits: 41.7 E(85289): 0.0068 Smith-Waterman score: 328; 23.3% identity (55.1% similar) in 477 aa overlap (123-571:24-460) 100 110 120 130 140 150 pF1KSD DPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGV : .. : .:.:..::.: : : :: . XP_016 MIQSQEKPDRVLVRVRDLTIQKADEVVWVRARVHTSRAKG-KQCFLVLRQQQF 10 20 30 40 50 160 170 180 190 200 210 pF1KSD KLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHM ..:... .. :.. .... .. . .:. :.: :... : .. : ... XP_016 NVQALVAVGDHASKQ-MVKFAANINKESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYV 60 70 80 90 100 110 220 230 240 250 pF1KSD L----PHLHFGLKD-----------------KETRYRQRYLDLILNDFVRQKFIIRSKII . :.: . : : ..:: .: .:: .. . : ..: : XP_016 ISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDL-RTSTSQAVFRLQSGIC 120 130 140 150 160 170 260 270 280 290 300 310 pF1KSD TYIRSFLDELGFLEIETP-MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVG .: : . ::.::.:: ... :.. ..: .. : :. .:.::..: . . XP_016 HLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKN---NAYLAQSPQLYKQMCICA 180 190 200 210 220 320 330 340 350 360 pF1KSD GIDRVYEIGRQFRNEGIDL-THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSY ...:. :: :: : . : ::. .. ::. .:: :. :.... ::. . : XP_016 DFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAF-NYH-YHEVMEEIADTMVQIFKG-L 230 240 250 260 270 280 370 380 390 400 410 420 pF1KSD KVTYHPDGPEGQAYDVDFT-PPFRRINMVEELE--KALGMKLPETNLFETEETRKILDDI . .. : :. . .: ::. .. . .:: .::.: : :... .: ::. XP_016 QERFQ---TEIQTVNKQFPCEPFKFLEPTLRLEYCEALAM-LREAGVEMGDE-----DDL 290 300 310 320 330 430 440 450 460 470 480 pF1KSD CVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICD-HPQIMSPLAKWHRSKEG-LTE . . .::.:.... . .: : .: . :. .. .. XP_016 STPN--------------EKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSN 340 350 360 370 380 490 500 510 520 530 540 pF1KSD RFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPT ...:. .:: .. ...:: ::. :.: .. : : . . . ....: :: XP_016 SYDMFMRGEEILSGAQRIHDP----QLLTERALHHGI-DLEKI---KAYIDSFRFGAPPH 390 400 410 420 430 550 560 570 580 590 pF1KSD AGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGSSV :: :.:..::.:.. .:.... .:: XP_016 AGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 440 450 460 >>NP_001340 (OMIM: 603084,615281) aspartate--tRNA ligase (501 aa) initn: 232 init1: 114 opt: 153 Z-score: 172.5 bits: 41.7 E(85289): 0.0072 Smith-Waterman score: 328; 23.3% identity (55.1% similar) in 477 aa overlap (123-571:57-493) 100 110 120 130 140 150 pF1KSD DPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGV : .. : .:.:..::.: : : :: . NP_001 ERYGISSMIQSQEKPDRVLVRVRDLTIQKADEVVWVRARVHTSRAKG-KQCFLVLRQQQF 30 40 50 60 70 80 160 170 180 190 200 210 pF1KSD KLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHM ..:... .. :.. .... .. . .:. :.: :... : .. : ... NP_001 NVQALVAVGDHASKQ-MVKFAANINKESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYV 90 100 110 120 130 140 220 230 240 250 pF1KSD L----PHLHFGLKD-----------------KETRYRQRYLDLILNDFVRQKFIIRSKII . :.: . : : ..:: .: .:: .. . : ..: : NP_001 ISLAEPRLPLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVIDL-RTSTSQAVFRLQSGIC 150 160 170 180 190 200 260 270 280 290 300 310 pF1KSD TYIRSFLDELGFLEIETP-MMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVG .: : . ::.::.:: ... :.. ..: .. : :. .:.::..: . . NP_001 HLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKN---NAYLAQSPQLYKQMCICA 210 220 230 240 250 260 320 330 340 350 360 pF1KSD GIDRVYEIGRQFRNEGIDL-THNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSY ...:. :: :: : . : ::. .. ::. .:: :. :.... ::. . : NP_001 DFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAF-NYH-YHEVMEEIADTMVQIFKG-L 270 280 290 300 310 370 380 390 400 410 420 pF1KSD KVTYHPDGPEGQAYDVDFT-PPFRRINMVEELE--KALGMKLPETNLFETEETRKILDDI . .. : :. . .: ::. .. . .:: .::.: : :... .: ::. NP_001 QERFQ---TEIQTVNKQFPCEPFKFLEPTLRLEYCEALAM-LREAGVEMGDE-----DDL 320 330 340 350 360 430 440 450 460 470 480 pF1KSD CVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICD-HPQIMSPLAKWHRSKEG-LTE . . .::.:.... . .: : .: . :. .. .. NP_001 STPN--------------EKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDPRNPKQSN 370 380 390 400 410 490 500 510 520 530 540 pF1KSD RFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPT ...:. .:: .. ...:: ::. :.: .. : : . . . ....: :: NP_001 SYDMFMRGEEILSGAQRIHDP----QLLTERALHHGI-DLEKI---KAYIDSFRFGAPPH 420 430 440 450 460 550 560 570 580 590 pF1KSD AGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGSSV :: :.:..::.:.. .:.... .:: NP_001 AGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 470 480 490 500 597 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 23:48:11 2016 done: Wed Nov 2 23:48:12 2016 Total Scan time: 8.720 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]