Result of FASTA (omim) for
pF1KSDA0119
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0119, 323 aa
1>>>pF1KSDA0119 323 - 323 aa - 323 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1094+/-0.000362; mu= 17.2106+/- 0.022
mean_var=67.6400+/-13.717, 0's: 0 Z-trim(112.5): 62 B-trim: 0 in 0/54
Lambda= 0.155945
statistics sampled from 21379 (21442) to 21379 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.251), width: 16
Scan time: 6.560
The best scores are: opt bits E(85289)
NP_003730 (OMIM: 603966) aldo-keto reductase famil ( 323) 2166 496.3 3.6e-140
NP_001240837 (OMIM: 603966) aldo-keto reductase fa ( 323) 2162 495.4 6.6e-140
NP_001344 (OMIM: 600449) aldo-keto reductase famil ( 323) 1924 441.8 8.7e-124
NP_995317 (OMIM: 600450,614279) aldo-keto reductas ( 323) 1904 437.3 2e-122
NP_001345 (OMIM: 600450,614279) aldo-keto reductas ( 323) 1904 437.3 2e-122
NP_001809 (OMIM: 600451,614279) aldo-keto reductas ( 323) 1841 423.2 3.6e-118
NP_005980 (OMIM: 235555,604741) 3-oxo-5-beta-stero ( 326) 1274 295.6 9.2e-80
NP_001177836 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 290) 1148 267.2 2.9e-71
XP_016871280 (OMIM: 600449) PREDICTED: aldo-keto r ( 297) 1063 248.1 1.7e-65
NP_001307956 (OMIM: 600450,614279) aldo-keto reduc ( 297) 1053 245.9 8e-65
NP_001619 (OMIM: 103880) aldose reductase isoform ( 316) 1046 244.3 2.5e-64
NP_064695 (OMIM: 604707) aldo-keto reductase famil ( 316) 990 231.7 1.5e-60
XP_011514543 (OMIM: 616336) PREDICTED: aldo-keto r ( 316) 950 222.7 7.9e-58
XP_016867713 (OMIM: 616336) PREDICTED: aldo-keto r ( 344) 926 217.3 3.6e-56
NP_001074007 (OMIM: 616336) aldo-keto reductase fa ( 344) 926 217.3 3.6e-56
NP_001189342 (OMIM: 103830) alcohol dehydrogenase ( 325) 870 204.7 2.1e-52
NP_697021 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 870 204.7 2.1e-52
NP_006057 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 870 204.7 2.1e-52
NP_001189343 (OMIM: 103830) alcohol dehydrogenase ( 325) 870 204.7 2.1e-52
NP_001240838 (OMIM: 603966) aldo-keto reductase fa ( 138) 808 190.5 1.7e-48
NP_001128713 (OMIM: 600450,614279) aldo-keto reduc ( 139) 715 169.6 3.4e-42
XP_011514718 (OMIM: 604707) PREDICTED: aldo-keto r ( 277) 649 154.9 1.7e-37
XP_005250291 (OMIM: 103880) PREDICTED: aldose redu ( 172) 596 142.9 4.6e-34
NP_001333071 (OMIM: 103880) aldose reductase isofo ( 172) 596 142.9 4.6e-34
NP_001177835 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 285) 558 134.5 2.6e-31
XP_011538794 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 533 128.8 1e-29
XP_011538793 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 533 128.8 1e-29
XP_011514719 (OMIM: 604707) PREDICTED: aldo-keto r ( 175) 418 102.8 5.3e-22
NP_036199 (OMIM: 608477) aflatoxin B1 aldehyde red ( 331) 155 43.9 0.00057
XP_011539348 (OMIM: 608477) PREDICTED: aflatoxin B ( 375) 155 43.9 0.00063
NP_003680 (OMIM: 603418) aflatoxin B1 aldehyde red ( 359) 143 41.2 0.004
NP_001186791 (OMIM: 601142) voltage-gated potassiu ( 415) 140 40.6 0.0071
XP_016858110 (OMIM: 601142) PREDICTED: voltage-gat ( 435) 140 40.6 0.0074
>>NP_003730 (OMIM: 603966) aldo-keto reductase family 1 (323 aa)
initn: 2166 init1: 2166 opt: 2166 Z-score: 2637.6 bits: 496.3 E(85289): 3.6e-140
Smith-Waterman score: 2166; 99.7% identity (100.0% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
250 260 270 280 290 300
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
:::::::::::::::::::::::
NP_003 RNLHYFNSDSFASHPNYPYSDEY
310 320
>>NP_001240837 (OMIM: 603966) aldo-keto reductase family (323 aa)
initn: 2162 init1: 2162 opt: 2162 Z-score: 2632.7 bits: 495.4 E(85289): 6.6e-140
Smith-Waterman score: 2162; 99.4% identity (100.0% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
::::.::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDSKHQCLKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
250 260 270 280 290 300
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
:::::::::::::::::::::::
NP_001 RNLHYFNSDSFASHPNYPYSDEY
310 320
>>NP_001344 (OMIM: 600449) aldo-keto reductase family 1 (323 aa)
initn: 1924 init1: 1924 opt: 1924 Z-score: 2343.3 bits: 441.8 E(85289): 8.7e-124
Smith-Waterman score: 1924; 87.9% identity (95.4% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
:::: ::::::::::::::::::::: :::.:::::.:::::::::::::::::::::::
NP_001 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
:::::::::::::::::::::::::: . ::::::::::: :::. ::::::::::: :.
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
:.:::::. : :::::..:: ::::.::::.:::::::::::::::::::::::::::::
NP_001 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::::. :::::::::::::::::::::.:.. ::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
:::::::::::::::::::::::::::::::::::::::::::::::::.:.:::::::.
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
250 260 270 280 290 300
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
::..:.. : ::. ::::.::::
NP_001 RNVRYLTLDIFAGPPNYPFSDEY
310 320
>>NP_995317 (OMIM: 600450,614279) aldo-keto reductase fa (323 aa)
initn: 1904 init1: 1904 opt: 1904 Z-score: 2319.0 bits: 437.3 E(85289): 2e-122
Smith-Waterman score: 1904; 87.0% identity (95.4% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
:::: ::::::::::::::::::::: :::.:::::..::::::::.::::::.::::::
NP_995 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
:::::::::::::::::::::::::::. ::::::::::: :::. ::::::::::: :.
NP_995 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
:.:::::. : :::::..:: ::::.:::::::::::::::::::::::.: ::::::::
NP_995 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::::. :::::::::::::::::::::.:.. ::::::::::::::
NP_995 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
:::::::::::::::::::::::::::::::::::::::::::::::::.:.:::::::.
NP_995 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
250 260 270 280 290 300
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
::..:.. : ::. ::::.::::
NP_995 RNVRYLTLDIFAGPPNYPFSDEY
310 320
>>NP_001345 (OMIM: 600450,614279) aldo-keto reductase fa (323 aa)
initn: 1904 init1: 1904 opt: 1904 Z-score: 2319.0 bits: 437.3 E(85289): 2e-122
Smith-Waterman score: 1904; 87.0% identity (95.4% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
:::: ::::::::::::::::::::: :::.:::::..::::::::.::::::.::::::
NP_001 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
:::::::::::::::::::::::::::. ::::::::::: :::. ::::::::::: :.
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
:.:::::. : :::::..:: ::::.:::::::::::::::::::::::.: ::::::::
NP_001 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::::. :::::::::::::::::::::.:.. ::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
:::::::::::::::::::::::::::::::::::::::::::::::::.:.:::::::.
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
250 260 270 280 290 300
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
::..:.. : ::. ::::.::::
NP_001 RNVRYLTLDIFAGPPNYPFSDEY
310 320
>>NP_001809 (OMIM: 600451,614279) aldo-keto reductase fa (323 aa)
initn: 1841 init1: 1841 opt: 1841 Z-score: 2242.4 bits: 423.2 E(85289): 3.6e-118
Smith-Waterman score: 1841; 84.2% identity (93.2% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
:: : : :.::::::::::::::::::::::..:.:::::::::::::::::.:::::::
NP_001 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
:::::::::::::::::::::::::: :: .:..:.::::.:::: :::::::::.: ::
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
.::::: : ::::::::: ::: .:::.::::::::::::::::::: ::::::::::
NP_001 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::.:.::::::::::::::::.::::.:: : ::::::::::::::
NP_001 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
::::::::::::::::::::::::::::::::::::::.:.::::::::.::::..:::.
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN
250 260 270 280 290 300
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
:: .: : . .::.::.::::
NP_001 RNYRYVVMDFLMDHPDYPFSDEY
310 320
>>NP_005980 (OMIM: 235555,604741) 3-oxo-5-beta-steroid 4 (326 aa)
initn: 1257 init1: 1198 opt: 1274 Z-score: 1552.9 bits: 295.6 E(85289): 9.2e-80
Smith-Waterman score: 1274; 56.2% identity (84.9% similar) in 317 aa overlap (8-323:10-326)
10 20 30 40 50
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPE-VPRSKALEVTKLAIEAGFRHIDSAHLYNN
. :.::. .:..:.:::. :. .:.. .:.::..:.::::.:..:.:
NP_005 MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH
:..:: ::: :::.:.:.:::::: .:::.: : ::.:::.:: .:. ::::::::.:.
NP_005 EHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL
::..:::.:. : ::::: .. .::.:::::: ::::::.::.:::::::::::.::
NP_005 VPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLE
::::::.::: :::::::::.. ::: ::...:::..::: ::..:. ::. .:: ::.
NP_005 NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAID
: .: .:.:....: : :.::...::::::. ::.: .::..: :.:.:.:: :.:: :.
NP_005 DALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIE
250 260 270 280 290 300
300 310 320
pF1KSD GLDRNLHYFNSDSFASHPNYPYSDEY
.:..:... . . .::.::. :::
NP_005 ALNKNVRFVELLMWRDHPEYPFHDEY
310 320
>>NP_001177836 (OMIM: 235555,604741) 3-oxo-5-beta-steroi (290 aa)
initn: 1131 init1: 1072 opt: 1148 Z-score: 1400.5 bits: 267.2 E(85289): 2.9e-71
Smith-Waterman score: 1148; 58.5% identity (85.6% similar) in 277 aa overlap (8-283:10-286)
10 20 30 40 50
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPE-VPRSKALEVTKLAIEAGFRHIDSAHLYNN
. :.::. .:..:.:::. :. .:.. .:.::..:.::::.:..:.:
NP_001 MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD EEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIH
:..:: ::: :::.:.:.:::::: .:::.: : ::.:::.:: .:. ::::::::.:.
NP_001 EHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL
::..:::.:. : ::::: .. .::.:::::: ::::::.::.:::::::::::.::
NP_001 VPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLE
::::::.::: :::::::::.. ::: ::...:::..::: ::..:. ::. .:: ::.
NP_001 NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAID
: .: .:.:....: : :.::...::::::. ::.: .::..: ::
NP_001 DALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQVARSS
250 260 270 280 290
300 310 320
pF1KSD GLDRNLHYFNSDSFASHPNYPYSDEY
>>XP_016871280 (OMIM: 600449) PREDICTED: aldo-keto reduc (297 aa)
initn: 1050 init1: 1050 opt: 1063 Z-score: 1297.0 bits: 248.1 E(85289): 1.7e-65
Smith-Waterman score: 1712; 82.0% identity (88.2% similar) in 323 aa overlap (1-323:1-297)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
:::: ::::::::::::::::::::: :::.:::::.:::::::::::::::::::::::
XP_016 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
:::::::::::::::::::::::::: . ::::::::::: :::. ::::::::::: :.
XP_016 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
:.: :.:::::::::::::::::::::::::::::
XP_016 SVK--------------------------AVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::::. :::::::::::::::::::::.:.. ::::::::::::::
XP_016 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
:::::::::::::::::::::::::::::::::::::::::::::::::.:.:::::::.
XP_016 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
220 230 240 250 260 270
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
::..:.. : ::. ::::.::::
XP_016 RNVRYLTLDIFAGPPNYPFSDEY
280 290
>>NP_001307956 (OMIM: 600450,614279) aldo-keto reductase (297 aa)
initn: 1040 init1: 1040 opt: 1053 Z-score: 1284.8 bits: 245.9 E(85289): 8e-65
Smith-Waterman score: 1692; 81.1% identity (88.2% similar) in 323 aa overlap (1-323:1-297)
10 20 30 40 50 60
pF1KSD MDSKQQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
:::: ::::::::::::::::::::: :::.:::::..::::::::.::::::.::::::
NP_001 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
:::::::::::::::::::::::::::. ::::::::::: :::. ::::::::::: :.
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
:.: ::::::::::::::::::::.: ::::::::
NP_001 SVK--------------------------AMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
130 140 150
190 200 210 220 230 240
pF1KSD GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
::::::::::::::::::. :::::::::::::::::::::.:.. ::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
:::::::::::::::::::::::::::::::::::::::::::::::::.:.:::::::.
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
220 230 240 250 260 270
310 320
pF1KSD RNLHYFNSDSFASHPNYPYSDEY
::..:.. : ::. ::::.::::
NP_001 RNVRYLTLDIFAGPPNYPFSDEY
280 290
323 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:04:12 2016 done: Thu Nov 3 00:04:14 2016
Total Scan time: 6.560 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]