Result of FASTA (omim) for
pF1KSDA0120
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0120, 199 aa
1>>>pF1KSDA0120 199 - 199 aa - 199 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1380+/-0.000328; mu= 14.4621+/- 0.020
mean_var=69.4353+/-14.403, 0's: 0 Z-trim(115.1): 75 B-trim: 782 in 2/52
Lambda= 0.153916
statistics sampled from 25214 (25289) to 25214 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.297), width: 16
Scan time: 5.740
The best scores are: opt bits E(85289)
NP_001264152 (OMIM: 604634) transgelin-2 isoform b ( 199) 1356 309.7 2e-84
NP_003555 (OMIM: 604634) transgelin-2 isoform b [H ( 199) 1356 309.7 2e-84
NP_001264153 (OMIM: 604634) transgelin-2 isoform a ( 220) 1356 309.7 2.1e-84
NP_037391 (OMIM: 607953) transgelin-3 [Homo sapien ( 199) 1003 231.3 7.8e-61
NP_001008273 (OMIM: 607953) transgelin-3 [Homo sap ( 199) 1003 231.3 7.8e-61
NP_001008274 (OMIM: 607953) transgelin-3 [Homo sap ( 199) 1003 231.3 7.8e-61
NP_001001522 (OMIM: 600818) transgelin [Homo sapie ( 201) 919 212.7 3.2e-55
NP_003177 (OMIM: 600818) transgelin [Homo sapiens] ( 201) 919 212.7 3.2e-55
XP_016855734 (OMIM: 602374) PREDICTED: calponin-3 ( 288) 394 96.2 5.3e-20
NP_001272985 (OMIM: 602374) calponin-3 isoform 3 [ ( 288) 394 96.2 5.3e-20
NP_001830 (OMIM: 602374) calponin-3 isoform 1 [Hom ( 329) 394 96.3 5.9e-20
NP_004359 (OMIM: 602373) calponin-2 isoform a [Hom ( 309) 390 95.3 1e-19
NP_001290 (OMIM: 600806) calponin-1 isoform 1 [Hom ( 297) 385 94.2 2.2e-19
XP_016881778 (OMIM: 600806) PREDICTED: calponin-1 ( 363) 385 94.3 2.6e-19
XP_005259798 (OMIM: 600806) PREDICTED: calponin-1 ( 247) 371 91.1 1.6e-18
NP_001295271 (OMIM: 600806) calponin-1 isoform 2 [ ( 247) 371 91.1 1.6e-18
NP_001295270 (OMIM: 600806) calponin-1 isoform 2 [ ( 247) 371 91.1 1.6e-18
NP_958434 (OMIM: 602373) calponin-2 isoform b [Hom ( 270) 314 78.4 1.1e-14
NP_001290428 (OMIM: 602373) calponin-2 isoform c [ ( 298) 185 49.8 5.1e-06
NP_001290430 (OMIM: 602373) calponin-2 isoform d [ ( 330) 174 47.4 3e-05
NP_001272984 (OMIM: 602374) calponin-3 isoform 2 [ ( 283) 162 44.7 0.00017
>>NP_001264152 (OMIM: 604634) transgelin-2 isoform b [Ho (199 aa)
initn: 1356 init1: 1356 opt: 1356 Z-score: 1636.8 bits: 309.7 E(85289): 2e-84
Smith-Waterman score: 1356; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
130 140 150 160 170 180
190
pF1KSD NRGASQAGMTGYGMPRQIL
:::::::::::::::::::
NP_001 NRGASQAGMTGYGMPRQIL
190
>>NP_003555 (OMIM: 604634) transgelin-2 isoform b [Homo (199 aa)
initn: 1356 init1: 1356 opt: 1356 Z-score: 1636.8 bits: 309.7 E(85289): 2e-84
Smith-Waterman score: 1356; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
130 140 150 160 170 180
190
pF1KSD NRGASQAGMTGYGMPRQIL
:::::::::::::::::::
NP_003 NRGASQAGMTGYGMPRQIL
190
>>NP_001264153 (OMIM: 604634) transgelin-2 isoform a [Ho (220 aa)
initn: 1356 init1: 1356 opt: 1356 Z-score: 1636.2 bits: 309.7 E(85289): 2.1e-84
Smith-Waterman score: 1356; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:22-220)
10 20 30
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCR
:::::::::::::::::::::::::::::::::::::::
NP_001 MSAFSLALALVSSPQPPPPIGMANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD KDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD AERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENP
130 140 150 160 170 180
160 170 180 190
pF1KSD RNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL
::::::::::::::::::::::::::::::::::::::::
NP_001 RNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL
190 200 210 220
>>NP_037391 (OMIM: 607953) transgelin-3 [Homo sapiens] (199 aa)
initn: 1019 init1: 1003 opt: 1003 Z-score: 1213.2 bits: 231.3 E(85289): 7.8e-61
Smith-Waterman score: 1003; 69.8% identity (89.4% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
::::::.::::::::.:::..::::::. :..:: :: .:. .: ::: .::.:: :::
NP_037 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
:::.:::.::: :: :. ::. : :::::::::::::.::: ::. ::::::::::::::
NP_037 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
.:: :::::: ::..::..::: . :.:.:: .:...: :.::..::..:.::::::::.
NP_037 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS
130 140 150 160 170 180
190
pF1KSD NRGASQAGMTGYGMPRQIL
:.::::::::::::::::.
NP_037 NKGASQAGMTGYGMPRQIM
190
>>NP_001008273 (OMIM: 607953) transgelin-3 [Homo sapiens (199 aa)
initn: 1019 init1: 1003 opt: 1003 Z-score: 1213.2 bits: 231.3 E(85289): 7.8e-61
Smith-Waterman score: 1003; 69.8% identity (89.4% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
::::::.::::::::.:::..::::::. :..:: :: .:. .: ::: .::.:: :::
NP_001 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
:::.:::.::: :: :. ::. : :::::::::::::.::: ::. ::::::::::::::
NP_001 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
.:: :::::: ::..::..::: . :.:.:: .:...: :.::..::..:.::::::::.
NP_001 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS
130 140 150 160 170 180
190
pF1KSD NRGASQAGMTGYGMPRQIL
:.::::::::::::::::.
NP_001 NKGASQAGMTGYGMPRQIM
190
>>NP_001008274 (OMIM: 607953) transgelin-3 [Homo sapiens (199 aa)
initn: 1019 init1: 1003 opt: 1003 Z-score: 1213.2 bits: 231.3 E(85289): 7.8e-61
Smith-Waterman score: 1003; 69.8% identity (89.4% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
::::::.::::::::.:::..::::::. :..:: :: .:. .: ::: .::.:: :::
NP_001 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGK
:::.:::.::: :: :. ::. : :::::::::::::.::: ::. ::::::::::::::
NP_001 VLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGT
.:: :::::: ::..::..::: . :.:.:: .:...: :.::..::..:.::::::::.
NP_001 DMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGS
130 140 150 160 170 180
190
pF1KSD NRGASQAGMTGYGMPRQIL
:.::::::::::::::::.
NP_001 NKGASQAGMTGYGMPRQIM
190
>>NP_001001522 (OMIM: 600818) transgelin [Homo sapiens] (201 aa)
initn: 930 init1: 567 opt: 919 Z-score: 1112.3 bits: 212.7 E(85289): 3.2e-55
Smith-Waterman score: 919; 65.0% identity (87.5% similar) in 200 aa overlap (1-199:1-200)
10 20 30 40 50 60
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
:::.::.::.:::::.::::.:: .::. :..:: .:: :::::. :: .:: :::.:.
NP_001 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
10 20 30 40 50 60
70 80 90 100 110
pF1KSD VLCELINALYPEGQAPVKKIQAS-TMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEG
.: .:.:.:::.:. ::: . .:.::::::..:::.::: ::. ::.::::::.::
NP_001 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD KNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMG
:.:: :::::: ::.:::...:: . :::::: ::..:. :.:...::::::.:::::::
NP_001 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
130 140 150 160 170 180
180 190
pF1KSD TNRGASQAGMTGYGMPRQIL
.::::::::::::: ::::.
NP_001 SNRGASQAGMTGYGRPRQIIS
190 200
>>NP_003177 (OMIM: 600818) transgelin [Homo sapiens] (201 aa)
initn: 930 init1: 567 opt: 919 Z-score: 1112.3 bits: 212.7 E(85289): 3.2e-55
Smith-Waterman score: 919; 65.0% identity (87.5% similar) in 200 aa overlap (1-199:1-200)
10 20 30 40 50 60
pF1KSD MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
:::.::.::.:::::.::::.:: .::. :..:: .:: :::::. :: .:: :::.:.
NP_003 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
10 20 30 40 50 60
70 80 90 100 110
pF1KSD VLCELINALYPEGQAPVKKIQAS-TMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEG
.: .:.:.:::.:. ::: . .:.::::::..:::.::: ::. ::.::::::.::
NP_003 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD KNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMG
:.:: :::::: ::.:::...:: . :::::: ::..:. :.:...::::::.:::::::
NP_003 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
130 140 150 160 170 180
180 190
pF1KSD TNRGASQAGMTGYGMPRQIL
.::::::::::::: ::::.
NP_003 SNRGASQAGMTGYGRPRQIIS
190 200
>>XP_016855734 (OMIM: 602374) PREDICTED: calponin-3 isof (288 aa)
initn: 539 init1: 174 opt: 394 Z-score: 480.0 bits: 96.2 E(85289): 5.3e-20
Smith-Waterman score: 394; 45.9% identity (73.0% similar) in 148 aa overlap (51-198:6-147)
30 40 50 60 70 80
pF1KSD QYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKI
::: :::: .:::::: : : . :::.
XP_016 MSIGPNFQLGLKDGIILCELINKLQP---GSVKKV
10 20 30
90 100 110 120 130 140
pF1KSD QASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARD
. :.. . :.:.:..:..: . ::.. :::.. ::.:. ::. :: ::. :.:: :.
XP_016 NESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGL--AKT
40 50 60 70 80 90
150 160 170 180 190
pF1KSD DGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL
: : . : .... : :....:. :..:::::::::. :::::::.:: :..
XP_016 KG-FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYD
100 110 120 130 140
XP_016 PKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTN
150 160 170 180 190 200
>>NP_001272985 (OMIM: 602374) calponin-3 isoform 3 [Homo (288 aa)
initn: 539 init1: 174 opt: 394 Z-score: 480.0 bits: 96.2 E(85289): 5.3e-20
Smith-Waterman score: 394; 45.9% identity (73.0% similar) in 148 aa overlap (51-198:6-147)
30 40 50 60 70 80
pF1KSD QYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKI
::: :::: .:::::: : : . :::.
NP_001 MSIGPNFQLGLKDGIILCELINKLQP---GSVKKV
10 20 30
90 100 110 120 130 140
pF1KSD QASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARD
. :.. . :.:.:..:..: . ::.. :::.. ::.:. ::. :: ::. :.:: :.
NP_001 NESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGL--AKT
40 50 60 70 80 90
150 160 170 180 190
pF1KSD DGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL
: : . : .... : :....:. :..:::::::::. :::::::.:: :..
NP_001 KG-FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYD
100 110 120 130 140
NP_001 PKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTN
150 160 170 180 190 200
199 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:05:34 2016 done: Thu Nov 3 00:05:35 2016
Total Scan time: 5.740 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]