FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0122, 929 aa 1>>>pF1KSDA0122 929 - 929 aa - 929 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0815+/-0.000399; mu= 6.7714+/- 0.025 mean_var=269.2750+/-56.488, 0's: 0 Z-trim(120.8): 46 B-trim: 0 in 0/55 Lambda= 0.078159 statistics sampled from 36352 (36413) to 36352 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.427), width: 16 Scan time: 12.370 The best scores are: opt bits E(85289) NP_001191396 (OMIM: 300080,311900) RNA-binding pro ( 929) 6200 713.1 1.6e-204 XP_005272734 (OMIM: 300080,311900) PREDICTED: RNA- ( 994) 6200 713.2 1.6e-204 NP_005667 (OMIM: 300080,311900) RNA-binding protei ( 930) 6188 711.8 4e-204 NP_001191397 (OMIM: 300080,311900) RNA-binding pro ( 995) 6188 711.8 4.2e-204 XP_005272736 (OMIM: 300080,311900) PREDICTED: RNA- ( 917) 5213 601.8 4.9e-171 NP_690595 (OMIM: 300080,311900) RNA-binding protei ( 852) 5211 601.6 5.5e-171 XP_005272735 (OMIM: 300080,311900) PREDICTED: RNA- ( 918) 5201 600.5 1.3e-170 NP_001191395 (OMIM: 300080,311900) RNA-binding pro ( 853) 5199 600.2 1.4e-170 XP_016885374 (OMIM: 300080,311900) PREDICTED: RNA- ( 726) 4809 556.2 2.2e-157 XP_016885373 (OMIM: 300080,311900) PREDICTED: RNA- ( 727) 4797 554.8 5.5e-157 XP_006724626 (OMIM: 300080,311900) PREDICTED: RNA- ( 727) 4797 554.8 5.5e-157 XP_011542291 (OMIM: 300080,311900) PREDICTED: RNA- ( 618) 4041 469.5 2.3e-131 XP_016860995 (OMIM: 606884) PREDICTED: RNA-binding ( 568) 1770 213.4 2.6e-54 XP_016860994 (OMIM: 606884) PREDICTED: RNA-binding ( 568) 1770 213.4 2.6e-54 XP_011531563 (OMIM: 606884) PREDICTED: RNA-binding ( 741) 1770 213.5 3.1e-54 NP_005769 (OMIM: 606884) RNA-binding protein 5 [Ho ( 815) 1770 213.5 3.4e-54 XP_016860992 (OMIM: 606884) PREDICTED: RNA-binding ( 815) 1770 213.5 3.4e-54 XP_016860996 (OMIM: 606884) PREDICTED: RNA-binding ( 509) 1514 184.5 1.2e-45 XP_016860993 (OMIM: 606884) PREDICTED: RNA-binding ( 682) 1514 184.6 1.4e-45 XP_006712980 (OMIM: 606884) PREDICTED: RNA-binding ( 756) 1514 184.6 1.6e-45 XP_016860988 (OMIM: 606886) PREDICTED: RNA-binding ( 601) 592 80.6 2.6e-14 NP_001161054 (OMIM: 606886) RNA-binding protein 6 ( 601) 592 80.6 2.6e-14 XP_016860991 (OMIM: 606886) PREDICTED: RNA-binding ( 601) 592 80.6 2.6e-14 XP_005264844 (OMIM: 606886) PREDICTED: RNA-binding ( 601) 592 80.6 2.6e-14 XP_016860989 (OMIM: 606886) PREDICTED: RNA-binding ( 601) 592 80.6 2.6e-14 XP_016860990 (OMIM: 606886) PREDICTED: RNA-binding ( 601) 592 80.6 2.6e-14 XP_005264843 (OMIM: 606886) PREDICTED: RNA-binding ( 601) 592 80.6 2.6e-14 XP_016860987 (OMIM: 606886) PREDICTED: RNA-binding ( 609) 592 80.6 2.6e-14 XP_016860986 (OMIM: 606886) PREDICTED: RNA-binding ( 638) 592 80.6 2.7e-14 XP_005264842 (OMIM: 606886) PREDICTED: RNA-binding ( 642) 592 80.6 2.7e-14 XP_006712979 (OMIM: 606886) PREDICTED: RNA-binding ( 991) 592 80.8 3.7e-14 XP_005264841 (OMIM: 606886) PREDICTED: RNA-binding ( 991) 592 80.8 3.7e-14 NP_005768 (OMIM: 606886) RNA-binding protein 6 iso (1123) 592 80.9 4.1e-14 XP_011531564 (OMIM: 606884) PREDICTED: RNA-binding ( 741) 521 72.7 7.8e-12 >>NP_001191396 (OMIM: 300080,311900) RNA-binding protein (929 aa) initn: 6200 init1: 6200 opt: 6200 Z-score: 3793.0 bits: 713.1 E(85289): 1.6e-204 Smith-Waterman score: 6200; 99.9% identity (99.9% similar) in 929 aa overlap (1-929:1-929) 10 20 30 40 50 60 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIEAAQLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIEAAQLLQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQGG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGPE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD ASLEPGADSVSMQAFSRPQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQS ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: NP_001 ASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD PSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD STASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGA 850 860 870 880 890 900 910 920 pF1KSD RGSSYGVTSTESYKETLHKTMVTRFNEAQ ::::::::::::::::::::::::::::: NP_001 RGSSYGVTSTESYKETLHKTMVTRFNEAQ 910 920 >>XP_005272734 (OMIM: 300080,311900) PREDICTED: RNA-bind (994 aa) initn: 6200 init1: 6200 opt: 6200 Z-score: 3792.6 bits: 713.2 E(85289): 1.6e-204 Smith-Waterman score: 6200; 99.9% identity (99.9% similar) in 929 aa overlap (1-929:66-994) 10 20 30 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENR :::::::::::::::::::::::::::::: XP_005 HGSSSGGGWEVKRSQRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENR 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSP 100 110 120 130 140 150 100 110 120 130 140 150 pF1KSD TGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQ 160 170 180 190 200 210 160 170 180 190 200 210 pF1KSD SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK 220 230 240 250 260 270 220 230 240 250 260 270 pF1KSD PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL 280 290 300 310 320 330 280 290 300 310 320 330 pF1KSD PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN 340 350 360 370 380 390 340 350 360 370 380 390 pF1KSD VRVIKDKQTQLNRGFAFIQLSTIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRVIKDKQTQLNRGFAFIQLSTIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMAS 400 410 420 430 440 450 400 410 420 430 440 450 pF1KSD NEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTE 460 470 480 490 500 510 460 470 480 490 500 510 pF1KSD SSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRPQPGAAPGIYQQS ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_005 SSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQS 520 530 540 550 560 570 520 530 540 550 560 570 pF1KSD AEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVST 580 590 600 610 620 630 580 590 600 610 620 630 pF1KSD YQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGA 640 650 660 670 680 690 640 650 660 670 680 690 pF1KSD PSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATAD 700 710 720 730 740 750 700 710 720 730 740 750 pF1KSD AGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE 760 770 780 790 800 810 760 770 780 790 800 810 pF1KSD KLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQ 820 830 840 850 860 870 820 830 840 850 860 870 pF1KSD MKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGW 880 890 900 910 920 930 880 890 900 910 920 pF1KSD KEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ 940 950 960 970 980 990 >>NP_005667 (OMIM: 300080,311900) RNA-binding protein 10 (930 aa) initn: 3809 init1: 3809 opt: 6188 Z-score: 3785.6 bits: 711.8 E(85289): 4e-204 Smith-Waterman score: 6188; 99.8% identity (99.8% similar) in 930 aa overlap (1-929:1-930) 10 20 30 40 50 60 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND 250 260 270 280 290 300 310 320 330 340 350 pF1KSD TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTI-EAAQLL ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_005 TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD QILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD GEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD EASLEPGADSVSMQAFSRPQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQ :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_005 EASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQ 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD SPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD QSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWAR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD SLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDD 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD RPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD SGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD ISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLG 850 860 870 880 890 900 900 910 920 pF1KSD ARGSSYGVTSTESYKETLHKTMVTRFNEAQ :::::::::::::::::::::::::::::: NP_005 ARGSSYGVTSTESYKETLHKTMVTRFNEAQ 910 920 930 >>NP_001191397 (OMIM: 300080,311900) RNA-binding protein (995 aa) initn: 3809 init1: 3809 opt: 6188 Z-score: 3785.3 bits: 711.8 E(85289): 4.2e-204 Smith-Waterman score: 6188; 99.8% identity (99.8% similar) in 930 aa overlap (1-929:66-995) 10 20 30 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENR :::::::::::::::::::::::::::::: NP_001 HGSSSGGGWEVKRSQRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENR 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSP 100 110 120 130 140 150 100 110 120 130 140 150 pF1KSD TGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQ 160 170 180 190 200 210 160 170 180 190 200 210 pF1KSD SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK 220 230 240 250 260 270 220 230 240 250 260 270 pF1KSD PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL 280 290 300 310 320 330 280 290 300 310 320 330 pF1KSD PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN 340 350 360 370 380 390 340 350 360 370 380 pF1KSD VRVIKDKQTQLNRGFAFIQLSTI-EAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMA ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: NP_001 VRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMA 400 410 420 430 440 450 390 400 410 420 430 440 pF1KSD SNEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGT 460 470 480 490 500 510 450 460 470 480 490 500 pF1KSD ESSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRPQPGAAPGIYQQ :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: NP_001 ESSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQ 520 530 540 550 560 570 510 520 530 540 550 560 pF1KSD SAEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVS 580 590 600 610 620 630 570 580 590 600 610 620 pF1KSD TYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETG 640 650 660 670 680 690 630 640 650 660 670 680 pF1KSD APSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATA 700 710 720 730 740 750 690 700 710 720 730 740 pF1KSD DAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPERE 760 770 780 790 800 810 750 760 770 780 790 800 pF1KSD EKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDME 820 830 840 850 860 870 810 820 830 840 850 860 pF1KSD QMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMG 880 890 900 910 920 930 870 880 890 900 910 920 pF1KSD WKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ 940 950 960 970 980 990 >>XP_005272736 (OMIM: 300080,311900) PREDICTED: RNA-bind (917 aa) initn: 5199 init1: 5199 opt: 5213 Z-score: 3191.6 bits: 601.8 E(85289): 4.9e-171 Smith-Waterman score: 5507; 91.6% identity (91.6% similar) in 929 aa overlap (1-929:66-917) 10 20 30 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENR :::::::::::::::::::::::::::::: XP_005 HGSSSGGGWEVKRSQRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENR 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSP ::::::::::::::::::::::::::::::::::::: XP_005 SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAE----------------------- 100 110 120 130 100 110 120 130 140 150 pF1KSD TGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQ :::::: XP_005 ------------------------------------------------------IRGQLQ 160 170 180 190 200 210 pF1KSD SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK 140 150 160 170 180 190 220 230 240 250 260 270 pF1KSD PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL 200 210 220 230 240 250 280 290 300 310 320 330 pF1KSD PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN 260 270 280 290 300 310 340 350 360 370 380 390 pF1KSD VRVIKDKQTQLNRGFAFIQLSTIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRVIKDKQTQLNRGFAFIQLSTIEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMAS 320 330 340 350 360 370 400 410 420 430 440 450 pF1KSD NEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTE 380 390 400 410 420 430 460 470 480 490 500 510 pF1KSD SSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRPQPGAAPGIYQQS ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_005 SSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQS 440 450 460 470 480 490 520 530 540 550 560 570 pF1KSD AEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVST 500 510 520 530 540 550 580 590 600 610 620 630 pF1KSD YQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGA 560 570 580 590 600 610 640 650 660 670 680 690 pF1KSD PSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATAD 620 630 640 650 660 670 700 710 720 730 740 750 pF1KSD AGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREE 680 690 700 710 720 730 760 770 780 790 800 810 pF1KSD KLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQ 740 750 760 770 780 790 820 830 840 850 860 870 pF1KSD MKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGW 800 810 820 830 840 850 880 890 900 910 920 pF1KSD KEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ 860 870 880 890 900 910 >>NP_690595 (OMIM: 300080,311900) RNA-binding protein 10 (852 aa) initn: 5199 init1: 5199 opt: 5211 Z-score: 3190.7 bits: 601.6 E(85289): 5.5e-171 Smith-Waterman score: 5507; 91.6% identity (91.6% similar) in 929 aa overlap (1-929:1-852) 10 20 30 40 50 60 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEED ::::::: NP_690 SEEQSAE----------------------------------------------------- 130 140 150 160 170 180 pF1KSD EEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH :::::::::::::::::::::::::::::::::::: NP_690 ------------------------IRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH 70 80 90 100 190 200 210 220 230 240 pF1KSD LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK 110 120 130 140 150 160 250 260 270 280 290 300 pF1KSD SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND 170 180 190 200 210 220 310 320 330 340 350 360 pF1KSD TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIEAAQLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIEAAQLLQ 230 240 250 260 270 280 370 380 390 400 410 420 pF1KSD ILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 ILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQGG 290 300 310 320 330 340 430 440 450 460 470 480 pF1KSD EGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 EGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGPE 350 360 370 380 390 400 490 500 510 520 530 540 pF1KSD ASLEPGADSVSMQAFSRPQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQS ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: NP_690 ASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQS 410 420 430 440 450 460 550 560 570 580 590 600 pF1KSD PTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 PTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQ 470 480 490 500 510 520 610 620 630 640 650 660 pF1KSD SQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 SQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARS 530 540 550 560 570 580 670 680 690 700 710 720 pF1KSD LNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 LNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDR 590 600 610 620 630 640 730 740 750 760 770 780 pF1KSD PSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 PSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLS 650 660 670 680 690 700 790 800 810 820 830 840 pF1KSD GLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 GLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGI 710 720 730 740 750 760 850 860 870 880 890 900 pF1KSD STASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_690 STASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGA 770 780 790 800 810 820 910 920 pF1KSD RGSSYGVTSTESYKETLHKTMVTRFNEAQ ::::::::::::::::::::::::::::: NP_690 RGSSYGVTSTESYKETLHKTMVTRFNEAQ 830 840 850 >>XP_005272735 (OMIM: 300080,311900) PREDICTED: RNA-bind (918 aa) initn: 4270 init1: 3809 opt: 5201 Z-score: 3184.2 bits: 600.5 E(85289): 1.3e-170 Smith-Waterman score: 5495; 91.5% identity (91.5% similar) in 930 aa overlap (1-929:66-918) 10 20 30 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENR :::::::::::::::::::::::::::::: XP_005 HGSSSGGGWEVKRSQRLRRGPSSPRRPYQDMEYERRGGRGDRTGRYGATDRSQDDGGENR 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSP ::::::::::::::::::::::::::::::::::::: XP_005 SRDHDYRDMDYRSYPREYGSQEGKHDYDDSSEEQSAE----------------------- 100 110 120 130 100 110 120 130 140 150 pF1KSD TGPPGFPRDGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLRMLPQAATEDDIRGQLQ :::::: XP_005 ------------------------------------------------------IRGQLQ 160 170 180 190 200 210 pF1KSD SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPK 140 150 160 170 180 190 220 230 240 250 260 270 pF1KSD PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLL 200 210 220 230 240 250 280 290 300 310 320 330 pF1KSD PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSN 260 270 280 290 300 310 340 350 360 370 380 pF1KSD VRVIKDKQTQLNRGFAFIQLSTI-EAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMA ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_005 VRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMA 320 330 340 350 360 370 390 400 410 420 430 440 pF1KSD SNEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGT 380 390 400 410 420 430 450 460 470 480 490 500 pF1KSD ESSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRPQPGAAPGIYQQ :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: XP_005 ESSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQ 440 450 460 470 480 490 510 520 530 540 550 560 pF1KSD SAEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAEASSSQGTAANSQSYTIMSPAVLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVS 500 510 520 530 540 550 570 580 590 600 610 620 pF1KSD TYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETG 560 570 580 590 600 610 630 640 650 660 670 680 pF1KSD APSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISSLRDDERRESATA 620 630 640 650 660 670 690 700 710 720 730 740 pF1KSD DAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPERE 680 690 700 710 720 730 750 760 770 780 790 800 pF1KSD EKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDME 740 750 760 770 780 790 810 820 830 840 850 860 pF1KSD QMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMG 800 810 820 830 840 850 870 880 890 900 910 920 pF1KSD WKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ 860 870 880 890 900 910 >>NP_001191395 (OMIM: 300080,311900) RNA-binding protein (853 aa) initn: 4270 init1: 3809 opt: 5199 Z-score: 3183.4 bits: 600.2 E(85289): 1.4e-170 Smith-Waterman score: 5495; 91.5% identity (91.5% similar) in 930 aa overlap (1-929:1-853) 10 20 30 40 50 60 pF1KSD MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSYPREYGSQEGKHDYDDS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEED ::::::: NP_001 SEEQSAE----------------------------------------------------- 130 140 150 160 170 180 pF1KSD EEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH :::::::::::::::::::::::::::::::::::: NP_001 ------------------------IRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSH 70 80 90 100 190 200 210 220 230 240 pF1KSD LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPK 110 120 130 140 150 160 250 260 270 280 290 300 pF1KSD SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENAND 170 180 190 200 210 220 310 320 330 340 350 pF1KSD TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTI-EAAQLL ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_001 TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLL 230 240 250 260 270 280 360 370 380 390 400 410 pF1KSD QILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQG 290 300 310 320 330 340 420 430 440 450 460 470 pF1KSD GEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGP 350 360 370 380 390 400 480 490 500 510 520 530 pF1KSD EASLEPGADSVSMQAFSRPQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQ :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_001 EASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQ 410 420 430 440 450 460 540 550 560 570 580 590 pF1KSD SPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNA 470 480 490 500 510 520 600 610 620 630 640 650 pF1KSD QSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWAR 530 540 550 560 570 580 660 670 680 690 700 710 pF1KSD SLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDD 590 600 610 620 630 640 720 730 740 750 760 770 pF1KSD RPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQL 650 660 670 680 690 700 780 790 800 810 820 830 pF1KSD SGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGG 710 720 730 740 750 760 840 850 860 870 880 890 pF1KSD ISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLG 770 780 790 800 810 820 900 910 920 pF1KSD ARGSSYGVTSTESYKETLHKTMVTRFNEAQ :::::::::::::::::::::::::::::: NP_001 ARGSSYGVTSTESYKETLHKTMVTRFNEAQ 830 840 850 >>XP_016885374 (OMIM: 300080,311900) PREDICTED: RNA-bind (726 aa) initn: 4809 init1: 4809 opt: 4809 Z-score: 2946.7 bits: 556.2 E(85289): 2.2e-157 Smith-Waterman score: 4809; 99.9% identity (99.9% similar) in 726 aa overlap (204-929:1-726) 180 190 200 210 220 230 pF1KSD AFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKC :::::::::::::::::::::::::::::: XP_016 MHYSDPKPKINEDWLCNKCGVQNFKRREKC 10 20 30 240 250 260 270 280 290 pF1KSD FKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KSD SSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTI 100 110 120 130 140 150 360 370 380 390 400 410 pF1KSD EAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAI 160 170 180 190 200 210 420 430 440 450 460 470 pF1KSD SQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGD 220 230 240 250 260 270 480 490 500 510 520 530 pF1KSD PTGAGPEASLEPGADSVSMQAFSRPQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAV :::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::: XP_016 PTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAV 280 290 300 310 320 330 540 550 560 570 580 590 pF1KSD LKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNS 340 350 360 370 380 390 600 610 620 630 640 650 pF1KSD QYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKD 400 410 420 430 440 450 660 670 680 690 700 710 pF1KSD MERWARSLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MERWARSLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLP 460 470 480 490 500 510 720 730 740 750 760 770 pF1KSD KLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEAL 520 530 540 550 560 570 780 790 800 810 820 830 pF1KSD IRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPK 580 590 600 610 620 630 840 850 860 870 880 890 pF1KSD RRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRV 640 650 660 670 680 690 900 910 920 pF1KSD RGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ :::::::::::::::::::::::::::::::::::: XP_016 RGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ 700 710 720 >>XP_016885373 (OMIM: 300080,311900) PREDICTED: RNA-bind (727 aa) initn: 3809 init1: 3809 opt: 4797 Z-score: 2939.3 bits: 554.8 E(85289): 5.5e-157 Smith-Waterman score: 4797; 99.7% identity (99.7% similar) in 727 aa overlap (204-929:1-727) 180 190 200 210 220 230 pF1KSD AFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKC :::::::::::::::::::::::::::::: XP_016 MHYSDPKPKINEDWLCNKCGVQNFKRREKC 10 20 30 240 250 260 270 280 290 pF1KSD FKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKCGVPKSEAEQKLPLGTRLDQQTLPLGGRELSQGLLPLPQPYQAQGVLASQALSQGSEP 40 50 60 70 80 90 300 310 320 330 340 350 pF1KSD SSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTI 100 110 120 130 140 150 360 370 380 390 400 410 pF1KSD -EAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWA 160 170 180 190 200 210 420 430 440 450 460 470 pF1KSD ISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKG 220 230 240 250 260 270 480 490 500 510 520 530 pF1KSD DPTGAGPEASLEPGADSVSMQAFSRPQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPA ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: XP_016 DPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPA 280 290 300 310 320 330 540 550 560 570 580 590 pF1KSD VLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLKSELQSPTHPSSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPN 340 350 360 370 380 390 600 610 620 630 640 650 pF1KSD SQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQYYYNAQSQQYLYWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAK 400 410 420 430 440 450 660 670 680 690 700 710 pF1KSD DMERWARSLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMERWARSLNKQKENFKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDL 460 470 480 490 500 510 720 730 740 750 760 770 pF1KSD PKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEA 520 530 540 550 560 570 780 790 800 810 820 830 pF1KSD LIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEP 580 590 600 610 620 630 840 850 860 870 880 890 pF1KSD KRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTR 640 650 660 670 680 690 900 910 920 pF1KSD VRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ ::::::::::::::::::::::::::::::::::::: XP_016 VRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ 700 710 720 929 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:06:17 2016 done: Thu Nov 3 00:06:18 2016 Total Scan time: 12.370 Total Display time: 0.320 Function used was FASTA [36.3.4 Apr, 2011]