Result of FASTA (omim) for
pF1KSDA0137
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0137, 766 aa
1>>>pF1KSDA0137 766 - 766 aa - 766 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1232+/-0.000496; mu= 1.5384+/- 0.031
mean_var=652.2119+/-147.670, 0's: 0 Z-trim(120.0): 416 B-trim: 0 in 0/60
Lambda= 0.050220
statistics sampled from 34112 (34737) to 34112 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.407), width: 16
Scan time: 9.000
The best scores are: opt bits E(85289)
NP_036422 (OMIM: 608438) serine/threonine-protein ( 766) 5105 386.2 2.8e-106
NP_001130026 (OMIM: 608438) serine/threonine-prote ( 718) 4784 362.9 2.7e-99
NP_001130027 (OMIM: 608438) serine/threonine-prote ( 670) 4392 334.4 9.3e-91
XP_016860910 (OMIM: 608438) PREDICTED: serine/thre ( 549) 3674 282.3 3.8e-75
XP_016860911 (OMIM: 608438) PREDICTED: serine/thre ( 549) 3674 282.3 3.8e-75
XP_011522522 (OMIM: 608439) PREDICTED: serine/thre ( 709) 2586 203.6 2.4e-51
XP_011510540 (OMIM: 608438) PREDICTED: serine/thre ( 703) 2558 201.6 9.5e-51
XP_011522525 (OMIM: 608439) PREDICTED: serine/thre ( 709) 2489 196.6 3.1e-49
XP_016879534 (OMIM: 608439) PREDICTED: serine/thre ( 764) 2438 192.9 4.1e-48
XP_011522520 (OMIM: 608439) PREDICTED: serine/thre ( 719) 2427 192.1 7e-48
XP_016879540 (OMIM: 608439) PREDICTED: serine/thre ( 718) 2411 190.9 1.6e-47
XP_016879541 (OMIM: 608439) PREDICTED: serine/thre ( 718) 2411 190.9 1.6e-47
XP_016879542 (OMIM: 608439) PREDICTED: serine/thre ( 718) 2411 190.9 1.6e-47
NP_001271292 (OMIM: 608439) serine/threonine-prote ( 718) 2411 190.9 1.6e-47
XP_016879543 (OMIM: 608439) PREDICTED: serine/thre ( 687) 2309 183.5 2.5e-45
XP_011522531 (OMIM: 608439) PREDICTED: serine/thre ( 623) 2298 182.7 4.2e-45
XP_011522527 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522526 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522529 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522528 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522530 (OMIM: 608439) PREDICTED: serine/thre ( 668) 2298 182.7 4.4e-45
XP_011522523 (OMIM: 608439) PREDICTED: serine/thre ( 740) 2298 182.8 4.6e-45
XP_016879537 (OMIM: 608439) PREDICTED: serine/thre ( 740) 2298 182.8 4.6e-45
XP_016879538 (OMIM: 608439) PREDICTED: serine/thre ( 740) 2298 182.8 4.6e-45
XP_011522518 (OMIM: 608439) PREDICTED: serine/thre ( 772) 2298 182.8 4.7e-45
XP_011522524 (OMIM: 608439) PREDICTED: serine/thre ( 772) 2298 182.8 4.7e-45
XP_011522519 (OMIM: 608439) PREDICTED: serine/thre ( 772) 2298 182.8 4.7e-45
NP_001271262 (OMIM: 608439) serine/threonine-prote ( 772) 2298 182.8 4.7e-45
XP_011522517 (OMIM: 608439) PREDICTED: serine/thre ( 741) 2296 182.6 5.1e-45
XP_016879539 (OMIM: 608439) PREDICTED: serine/thre ( 733) 2293 182.4 5.9e-45
XP_016879548 (OMIM: 608439) PREDICTED: serine/thre ( 601) 2287 181.8 7.2e-45
NP_001317347 (OMIM: 608439) serine/threonine-prote ( 601) 2287 181.8 7.2e-45
XP_016879545 (OMIM: 608439) PREDICTED: serine/thre ( 646) 2287 181.9 7.4e-45
XP_016879546 (OMIM: 608439) PREDICTED: serine/thre ( 646) 2287 181.9 7.4e-45
XP_016879549 (OMIM: 608439) PREDICTED: serine/thre ( 538) 2285 181.6 7.5e-45
XP_016879533 (OMIM: 608439) PREDICTED: serine/thre ( 750) 2287 182.0 8e-45
XP_016879535 (OMIM: 608439) PREDICTED: serine/thre ( 750) 2287 182.0 8e-45
NP_006843 (OMIM: 608439) serine/threonine-protein ( 750) 2287 182.0 8e-45
XP_016879536 (OMIM: 608439) PREDICTED: serine/thre ( 750) 2287 182.0 8e-45
XP_016879544 (OMIM: 608439) PREDICTED: serine/thre ( 655) 2285 181.8 8.3e-45
XP_011522533 (OMIM: 608439) PREDICTED: serine/thre ( 517) 916 82.4 5.3e-15
NP_009125 (OMIM: 114480,176807,259500,604373,60926 ( 543) 360 42.1 0.0073
XP_011537101 (OMIM: 603168) PREDICTED: serine/thre (1044) 366 43.0 0.0075
NP_003556 (OMIM: 603168) serine/threonine-protein (1050) 366 43.0 0.0075
XP_016884049 (OMIM: 114480,176807,259500,604373,60 ( 584) 360 42.2 0.0076
NP_001005735 (OMIM: 114480,176807,259500,604373,60 ( 586) 360 42.2 0.0076
XP_011537100 (OMIM: 603168) PREDICTED: serine/thre (1073) 366 43.1 0.0076
XP_011528141 (OMIM: 114480,176807,259500,604373,60 ( 596) 360 42.2 0.0076
>>NP_036422 (OMIM: 608438) serine/threonine-protein kina (766 aa)
initn: 5105 init1: 5105 opt: 5105 Z-score: 2029.0 bits: 386.2 E(85289): 2.8e-106
Smith-Waterman score: 5105; 100.0% identity (100.0% similar) in 766 aa overlap (1-766:1-766)
10 20 30 40 50 60
pF1KSD MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD GHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 STNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
670 680 690 700 710 720
730 740 750 760
pF1KSD DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
730 740 750 760
>>NP_001130026 (OMIM: 608438) serine/threonine-protein k (718 aa)
initn: 4784 init1: 4784 opt: 4784 Z-score: 1903.6 bits: 362.9 E(85289): 2.7e-99
Smith-Waterman score: 4784; 100.0% identity (100.0% similar) in 718 aa overlap (49-766:1-718)
20 30 40 50 60 70
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
::::::::::::::::::::::::::::::
NP_001 MDELHSLDPRRQELLEARFTGVASGSTGST
10 20 30
80 90 100 110 120 130
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KSD IGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGD
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD HPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQK
160 170 180 190 200 210
260 270 280 290 300 310
pF1KSD LLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTD
220 230 240 250 260 270
320 330 340 350 360 370
pF1KSD GFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAE
280 290 300 310 320 330
380 390 400 410 420 430
pF1KSD NDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRI
340 350 360 370 380 390
440 450 460 470 480 490
pF1KSD NNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKK
400 410 420 430 440 450
500 510 520 530 540 550
pF1KSD ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSE
460 470 480 490 500 510
560 570 580 590 600 610
pF1KSD KEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDS
520 530 540 550 560 570
620 630 640 650 660 670
pF1KSD YGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQ
580 590 600 610 620 630
680 690 700 710 720 730
pF1KSD SQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHM
640 650 660 670 680 690
740 750 760
pF1KSD RRSNSSGNLHMAGLTASPTPPSSSIITY
::::::::::::::::::::::::::::
NP_001 RRSNSSGNLHMAGLTASPTPPSSSIITY
700 710
>>NP_001130027 (OMIM: 608438) serine/threonine-protein k (670 aa)
initn: 4392 init1: 4392 opt: 4392 Z-score: 1750.4 bits: 334.4 E(85289): 9.3e-91
Smith-Waterman score: 4392; 99.8% identity (100.0% similar) in 657 aa overlap (110-766:14-670)
80 90 100 110 120 130
pF1KSD SCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKSI
.:::::::::::::::::::::::::::::
NP_001 MAVLFLYDLKTTGKTPEKKQSESSRGRKRKAENQNESSQGKSI
10 20 30 40
140 150 160 170 180 190
pF1KSD GGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPSSSVRPNSPSPTALAFGDH
50 60 70 80 90 100
200 210 220 230 240 250
pF1KSD PIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKL
110 120 130 140 150 160
260 270 280 290 300 310
pF1KSD LEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDG
170 180 190 200 210 220
320 330 340 350 360 370
pF1KSD FAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAEN
230 240 250 260 270 280
380 390 400 410 420 430
pF1KSD DPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIN
290 300 310 320 330 340
440 450 460 470 480 490
pF1KSD NEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKE
350 360 370 380 390 400
500 510 520 530 540 550
pF1KSD NYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEK
410 420 430 440 450 460
560 570 580 590 600 610
pF1KSD EARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSY
470 480 490 500 510 520
620 630 640 650 660 670
pF1KSD GVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQS
530 540 550 560 570 580
680 690 700 710 720 730
pF1KSD QQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMR
590 600 610 620 630 640
740 750 760
pF1KSD RSNSSGNLHMAGLTASPTPPSSSIITY
:::::::::::::::::::::::::::
NP_001 RSNSSGNLHMAGLTASPTPPSSSIITY
650 660 670
>>XP_016860910 (OMIM: 608438) PREDICTED: serine/threonin (549 aa)
initn: 3674 init1: 3674 opt: 3674 Z-score: 1470.0 bits: 282.3 E(85289): 3.8e-75
Smith-Waterman score: 3674; 100.0% identity (100.0% similar) in 549 aa overlap (218-766:1-549)
190 200 210 220 230 240
pF1KSD SPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANC
::::::::::::::::::::::::::::::
XP_016 MLKLAALESNKIQDLEKKEGRIDDLLRANC
10 20 30
250 260 270 280 290 300
pF1KSD DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
40 50 60 70 80 90
310 320 330 340 350 360
pF1KSD HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
100 110 120 130 140 150
370 380 390 400 410 420
pF1KSD QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
160 170 180 190 200 210
430 440 450 460 470 480
pF1KSD RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
220 230 240 250 260 270
490 500 510 520 530 540
pF1KSD QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
280 290 300 310 320 330
550 560 570 580 590 600
pF1KSD FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
340 350 360 370 380 390
610 620 630 640 650 660
pF1KSD FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
400 410 420 430 440 450
670 680 690 700 710 720
pF1KSD LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
460 470 480 490 500 510
730 740 750 760
pF1KSD LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
:::::::::::::::::::::::::::::::::::::::
XP_016 LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
520 530 540
>>XP_016860911 (OMIM: 608438) PREDICTED: serine/threonin (549 aa)
initn: 3674 init1: 3674 opt: 3674 Z-score: 1470.0 bits: 282.3 E(85289): 3.8e-75
Smith-Waterman score: 3674; 100.0% identity (100.0% similar) in 549 aa overlap (218-766:1-549)
190 200 210 220 230 240
pF1KSD SPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANC
::::::::::::::::::::::::::::::
XP_016 MLKLAALESNKIQDLEKKEGRIDDLLRANC
10 20 30
250 260 270 280 290 300
pF1KSD DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVR
40 50 60 70 80 90
310 320 330 340 350 360
pF1KSD HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPK
100 110 120 130 140 150
370 380 390 400 410 420
pF1KSD QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
160 170 180 190 200 210
430 440 450 460 470 480
pF1KSD RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
220 230 240 250 260 270
490 500 510 520 530 540
pF1KSD QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
280 290 300 310 320 330
550 560 570 580 590 600
pF1KSD FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
340 350 360 370 380 390
610 620 630 640 650 660
pF1KSD FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
400 410 420 430 440 450
670 680 690 700 710 720
pF1KSD LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
460 470 480 490 500 510
730 740 750 760
pF1KSD LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
:::::::::::::::::::::::::::::::::::::::
XP_016 LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
520 530 540
>>XP_011522522 (OMIM: 608439) PREDICTED: serine/threonin (709 aa)
initn: 3197 init1: 1487 opt: 2586 Z-score: 1043.0 bits: 203.6 E(85289): 2.4e-51
Smith-Waterman score: 3352; 72.4% identity (84.3% similar) in 733 aa overlap (49-762:2-706)
20 30 40 50 60 70
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
:.::::::::::::::::::::.
XP_011 MMEELHSLDPRRQELLEARFTGVGV------
10 20
80 90 100 110 120 130
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
.:. :.::::.:. :.::::::: :::::::... :.:::::: :.::::.
XP_011 ------SKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAEPY-ETSQGKG
30 40 50 60 70
140 150 160 170 180 190
pF1KSD IGGRGHKISDYFEYQGGN--GSSPVRGIPPAIRS-PQNSHSHSTPSSSVRP--NSPSPTA
::::::::::. ::. :.:: :..::. :: ::.: :. : .: . . .:
XP_011 TP-RGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGLDGSAA
80 90 100 110 120 130
200 210 220 230 240 250
pF1KSD LAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQI
.. . : .: . . : .:: .. : .. :::::::::
XP_011 KEATEEQSALPTLMSVMLAKPRLDTEQLA----------QRGAGLCFTFVSANCDLRRQI
140 150 160 170 180
260 270 280 290 300 310
pF1KSD DEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFT
:::::.:::::::::.:..:::::::::: :::.. :.::::::::::::::::::::::
XP_011 DEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFT
190 200 210 220 230 240
320 330 340 350 360 370
pF1KSD EQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKA
::::::.:::::.:::: .:.:::.::::::.:::::::. . ::: ...: ::::.:.
XP_011 EQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMG--QAPPATNEQKQRKSKT
250 260 270 280 290 300
380 390 400 410 420
pF1KSD VNGAEND-PF-----VRPNLPQL-------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
:::::. : .. . : : ::::::::::::::::::::::::::::::
XP_011 -NGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
310 320 330 340 350 360
430 440 450 460 470 480
pF1KSD LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
::::::::::::::::::.::::::::::::::.:::::::::::::::::::::: :::
XP_011 LERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQR
370 380 390 400 410 420
490 500 510 520 530 540
pF1KSD YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
:.:::::::::.::::::::::::::::::::::::::::::::::::::::.:::::::
XP_011 YVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEY
430 440 450 460 470 480
550 560 570 580 590 600
pF1KSD CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
::::::::::::::::::::::::.:::::::.::::::::::::::::::::::.::::
XP_011 CEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTAC
490 500 510 520 530 540
610 620 630 640 650
pF1KSD GEIKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWS
:::::::::::::::::::. ::::.::::::::::::::::::::::::::::::::::
XP_011 GEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWS
550 560 570 580 590 600
660 670 680 690 700 710
pF1KSD VGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRK
:::::.::::::::::::::::::::::::::::::::: ::::. ::::::::::::::
XP_011 VGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRK
610 620 630 640 650 660
720 730 740 750 760
pF1KSD EDRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
:::.::.::: :::::::.:.: :... :..... ..:
XP_011 EDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
670 680 690 700
>>XP_011510540 (OMIM: 608438) PREDICTED: serine/threonin (703 aa)
initn: 4664 init1: 2541 opt: 2558 Z-score: 1032.0 bits: 201.6 E(85289): 9.5e-51
Smith-Waterman score: 4542; 91.8% identity (91.8% similar) in 766 aa overlap (1-766:1-703)
10 20 30 40 50 60
pF1KSD MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSVRPNSPSPTALAFGDHPIVQPKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRID
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD GHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAP
:::::::::::::::::::::::::::
XP_011 GHFTTVRHGASFTEQWTDGFAFQNLVK---------------------------------
310 320
370 380 390 400 410 420
pF1KSD STNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
::::::::::::::::::::::::::::::
XP_011 ------------------------------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAE
330 340 350
430 440 450 460 470 480
pF1KSD LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQR
360 370 380 390 400 410
490 500 510 520 530 540
pF1KSD YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEY
420 430 440 450 460 470
550 560 570 580 590 600
pF1KSD CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTAC
480 490 500 510 520 530
610 620 630 640 650 660
pF1KSD GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEIKITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSV
540 550 560 570 580 590
670 680 690 700 710 720
pF1KSD GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKE
600 610 620 630 640 650
730 740 750 760
pF1KSD DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
660 670 680 690 700
>>XP_011522525 (OMIM: 608439) PREDICTED: serine/threonin (709 aa)
initn: 3218 init1: 1487 opt: 2489 Z-score: 1005.0 bits: 196.6 E(85289): 3.1e-49
Smith-Waterman score: 3243; 71.0% identity (84.3% similar) in 731 aa overlap (49-762:2-706)
20 30 40 50 60 70
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
:.::::::::::::::::::::.
XP_011 MMEELHSLDPRRQELLEARFTGVGV------
10 20
80 90 100 110 120 130
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
.:. :.::::.:. :.::::::: :::::::... :.:::::: :.::::.
XP_011 ------SKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAE-PYETSQGKG
30 40 50 60 70
140 150 160 170 180 190
pF1KSD IGGRGHKISDYFEYQGGNGSSPVRGIPPAIRSPQNSHSHSTPS-SSVRPNSPSPTALAFG
:::::::::: . .:. :. . . . .. . :. :: .: .
XP_011 TP-RGHKISDYFERR---VEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPR-----LD
80 90 100 110 120
200 210 220 230 240 250
pF1KSD DHPIVQ-PKQLSFKIIQTDLTMLKLAALESNKIQDLEKKEGRIDD-LLRANCDLRRQIDE
. ..: : : ..... . . .. ... . .:. :. .:::::::::::
XP_011 TEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQANCDLRRQIDE
130 140 150 160 170 180
260 270 280 290 300 310
pF1KSD QQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQ
:::.:::::::::.:..:::::::::: :::.. :.::::::::::::::::::::::::
XP_011 QQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQ
190 200 210 220 230 240
320 330 340 350 360 370
pF1KSD WTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVN
::::.:::::.:::: .:.:::.::::::.:::::::. . ::: ...: ::::.:. :
XP_011 WTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMG--QAPPATNEQKQRKSKT-N
250 260 270 280 290 300
380 390 400 410 420
pF1KSD GAEND-PF-----VRPNLPQL-------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELE
::::. : .. . : : ::::::::::::::::::::::::::::::::
XP_011 GAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELE
310 320 330 340 350 360
430 440 450 460 470 480
pF1KSD RLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYA
::::::::::::::::.::::::::::::::.:::::::::::::::::::::: ::::.
XP_011 RLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYV
370 380 390 400 410 420
490 500 510 520 530 540
pF1KSD AVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCE
:::::::::.::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 AVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCE
430 440 450 460 470 480
550 560 570 580 590 600
pF1KSD GNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGE
::::::::::::::::::::::.:::::::.::::::::::::::::::::::.::::::
XP_011 GNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGE
490 500 510 520 530 540
610 620 630 640 650 660
pF1KSD IKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVG
:::::::::::::::::. ::::.::::::::::::::::::::::::::::::::::::
XP_011 IKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVG
550 560 570 580 590 600
670 680 690 700 710 720
pF1KSD VIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKED
:::.::::::::::::::::::::::::::::::::: ::::. ::::::::::::::::
XP_011 VIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKED
610 620 630 640 650 660
730 740 750 760
pF1KSD RFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
:.::.::: :::::::.:.: :... :..... ..:
XP_011 RIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
670 680 690 700
>>XP_016879534 (OMIM: 608439) PREDICTED: serine/threonin (764 aa)
initn: 3363 init1: 1488 opt: 2438 Z-score: 984.7 bits: 192.9 E(85289): 4.1e-48
Smith-Waterman score: 3450; 70.5% identity (82.7% similar) in 790 aa overlap (8-762:2-761)
10 20 30 40 50
pF1KSD MSVQSSSGSLEGPPSWSQLSTSPTPGSAAAARSLLNHTPPSGRPREGA--------MDEL
: .. :.:. . : . . : . :: ::::: : :.::
XP_016 MGEAQAAPAWDW-GRRPEERRGPPG-SWRPRQPP-GRPREPALPSSVTEMMEEL
10 20 30 40 50
60 70 80 90 100 110
pF1KSD HSLDPRRQELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDKESETP
::::::::::::::::::. .:. :.::::.:. :.::::::: :::
XP_016 HSLDPRRQELLEARFTGVGV------------SKGPLNSESSNQSLCSVGSLSDKEVETP
60 70 80 90
120 130 140 150 160
pF1KSD EKKQSESSRGRKRKAENQNESSQGKSIGGRGHKISDYFEYQ------GGNGSSPVRG---
::::... :.:::::: :.::::. :::::::::: . : .::. ..
XP_016 EKKQNDQ-RNRKRKAEPY-ETSQGKGTP-RGHKISDYFERRVEQPLYGLDGSAAKEATEE
100 110 120 130 140 150
170 180 190 200
pF1KSD ---IP---------PAIRSPQNSHSHST---PSSSVRPNSPSPTALAFGDHPIVQPKQLS
.: : . . : .. . :.. :::: :. . .: . ::.:
XP_016 QSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQIS
160 170 180 190 200 210
210 220 230 240 250 260
pF1KSD F--KIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKLLEKYKER
. . :.:::. :..:::..: .::::::::::::::::::::::::::::.:::::::
XP_016 IQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKER
220 230 240 250 260 270
270 280 290 300 310 320
pF1KSD LNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLV
::.:..:::::::::: :::.. :.::::::::::::::::::::::::::::.:::::.
XP_016 LNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLI
280 290 300 310 320 330
330 340 350 360 370 380
pF1KSD KQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPN
:::: .:.:::.::::::.:::::::. .::: ...: ::::.:. :::::.
XP_016 KQQERINSQREEIERQRKMLAKRKPPAM--GQAPPATNEQKQRKSKT-NGAENET-----
340 350 360 370 380
390 400 410 420 430 440
pF1KSD LPQLLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQF
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 ----LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQF
390 400 410 420 430 440
450 460 470 480 490 500
pF1KSD KDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHAC
:::::::.:::::::::::::::::::::: ::::.:::::::::.::::::::::::::
XP_016 KDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHAC
450 460 470 480 490 500
510 520 530 540 550 560
pF1KSD REYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVM
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::.:
XP_016 REYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIM
510 520 530 540 550 560
570 580 590 600 610 620
pF1KSD QIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYG-VDGMD
::::::.::::::::::::::::::::::.:::::::::::::::::::::::. ::::.
XP_016 QIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGME
570 580 590 600 610 620
630 640 650 660 670 680
pF1KSD LTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQ
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_016 LTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQ
630 640 650 660 670 680
690 700 710 720 730 740
pF1KSD ENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSG
::::::::::::: ::::. :::::::::::::::::.::.::: :::::::.:.: :..
XP_016 ENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTS
690 700 710 720 730 740
750 760
pF1KSD NLHMAGLTASPTPPSSSIITY
. :..... ..:
XP_016 SPAGAAIASTSGASNNSSSN
750 760
>>XP_011522520 (OMIM: 608439) PREDICTED: serine/threonin (719 aa)
initn: 3197 init1: 1488 opt: 2427 Z-score: 980.7 bits: 192.1 E(85289): 7e-48
Smith-Waterman score: 3327; 71.6% identity (84.1% similar) in 742 aa overlap (49-762:2-716)
20 30 40 50 60 70
pF1KSD LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
:.::::::::::::::::::::.
XP_011 MMEELHSLDPRRQELLEARFTGVGV------
10 20
80 90 100 110 120 130
pF1KSD GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
.:. :.::::.:. :.::::::: :::::::... :.:::::: :.::::.
XP_011 ------SKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAE-PYETSQGKG
30 40 50 60 70
140 150 160 170 180
pF1KSD IGGRGHKISDYFEYQGGN--GSSPVRGIPPAIRS-PQNSHSHSTPSSSVRP---------
::::::::::. ::. :.:: :..::. :: ::.: :. : .:
XP_011 TP-RGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGLDGSAA
80 90 100 110 120 130
190 200 210 220 230
pF1KSD ------NSPSPTALAFG-DHPIVQPKQLSFKIIQTDLTMLKL-----AALESNKIQDLEK
.: :: .. .: .. .::. . .:... .. :.. . .
XP_011 KEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCS
140 150 160 170 180 190
240 250 260 270 280 290
pF1KSD KEGRIDDLLR---ANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSSRE
.. .:. : ::::::::::::::.:::::::::.:..:::::::::: :::.. :.
XP_011 SQKQISIQHRQTQANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRD
200 210 220 230 240 250
300 310 320 330 340 350
pF1KSD KSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKP
::::::::::::::::::::::::::::.:::::.:::: .:.:::.::::::.::::::
XP_011 KSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKP
260 270 280 290 300 310
360 370 380 390 400 410
pF1KSD PTANNSQAPSTNSEPKQRKNKAVNGAENDPFVRPNLPQLLTLAEYHEQEEIFKLRLGHLK
:. . ::: ...: ::::.:. :::::. :::::::::::::::::::::
XP_011 PAMG--QAPPATNEQKQRKSKT-NGAENET---------LTLAEYHEQEEIFKLRLGHLK
320 330 340 350 360
420 430 440 450 460 470
pF1KSD KEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVY
:::::::::::::::::::::::::::.::::::::::::::.:::::::::::::::::
XP_011 KEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVY
370 380 390 400 410 420
480 490 500 510 520 530
pF1KSD KAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDT
::::: ::::.:::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 KAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDT
430 440 450 460 470 480
540 550 560 570 580 590
pF1KSD DTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGN
:.:::::::::::::::::::::::::::::::.:::::::.::::::::::::::::::
XP_011 DSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGN
490 500 510 520 530 540
600 610 620 630 640 650
pF1KSD ILLVDGTACGEIKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPK
::::.:::::::::::::::::::::::. ::::.:::::::::::::::::::::::::
XP_011 ILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPK
550 560 570 580 590 600
660 670 680 690 700 710
pF1KSD ISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAF
::::::::::::::.::::::::::::::::::::::::::::::::: ::::. :::::
XP_011 ISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAF
610 620 630 640 650 660
720 730 740 750 760
pF1KSD IRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
::::::::::::.::.::: :::::::.:.: :... :..... ..:
XP_011 IRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
670 680 690 700 710
766 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:10:58 2016 done: Thu Nov 3 00:10:59 2016
Total Scan time: 9.000 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]