FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0140, 422 aa 1>>>pF1KSDA0140 422 - 422 aa - 422 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7606+/-0.000683; mu= 12.1299+/- 0.042 mean_var=116.0212+/-22.948, 0's: 0 Z-trim(114.3): 10 B-trim: 120 in 1/52 Lambda= 0.119071 statistics sampled from 14904 (14911) to 14904 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.458), width: 16 Scan time: 2.710 The best scores are: opt bits E(32554) CCDS7641.1 FAM53B gene_id:9679|Hs108|chr10 ( 422) 2970 520.5 1.2e-147 CCDS4204.1 FAM53C gene_id:51307|Hs108|chr5 ( 392) 432 84.5 2e-16 CCDS75091.1 FAM53A gene_id:152877|Hs108|chr4 ( 360) 323 65.7 8e-11 CCDS33939.1 FAM53A gene_id:152877|Hs108|chr4 ( 398) 323 65.8 8.7e-11 >>CCDS7641.1 FAM53B gene_id:9679|Hs108|chr10 (422 aa) initn: 2970 init1: 2970 opt: 2970 Z-score: 2764.2 bits: 520.5 E(32554): 1.2e-147 Smith-Waterman score: 2970; 99.8% identity (100.0% similar) in 422 aa overlap (1-422:1-422) 10 20 30 40 50 60 pF1KSD MVMVLSESLSTRGADSIACGTFSRELHTPKKMSQGPTLFSCGIMENDRWRDLDRKCPLQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MVMVLSESLSTRGADSIACGTFSRELHTPKKMSQGPTLFSCGIMENDRWRDLDRKCPLQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DQPSTSIWECLPEKDSSLWHREAVTACAVTSLIKDLSISDHNGNPSAPPSKRQCRSLSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DQPSTSIWECLPEKDSSLWHREAVTACAVTSLIKDLSISDHNGNPSAPPSKRQCRSLSFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSSFSLPSRANVLSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 DEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSSFSLPSRANVLSSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CDQAGLHHRFGGQPCQGVPGSAPCGQAGDTWSPDLHPVGGGRLDLQRSLSCSHEQFSFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 CDQAGLHHRFGGQPCQGVPGSAPCGQAGDTWSPDLHPVGGGRLDLQRSLSCSHEQFSFVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YCPPSANSTPASTPELARRSSGLSRSRSQPCVLNDKKVGVKRRRPEEVQEQRPSLDLAKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 YCPPSANSTPASTPELARRSSGLSRSRSQPCVLNDKKVGVKRRRPEEVQEQRPSLDLAKM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNTRAWTALLSASGPGGRTPAGTPVPEPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 AQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNTRAWTALLSASGPGGRTPAGTPVPEPLP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PSFDDHLVCQEDLSCEESDSCALDEDCGRRAEPAAAWRDRGAPGNSLCSLDGELDIEQIE :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 PSFDDHLACQEDLSCEESDSCALDEDCGRRAEPAAAWRDRGAPGNSLCSLDGELDIEQIE 370 380 390 400 410 420 pF1KSD KN :: CCDS76 KN >>CCDS4204.1 FAM53C gene_id:51307|Hs108|chr5 (392 aa) initn: 391 init1: 179 opt: 432 Z-score: 408.4 bits: 84.5 E(32554): 2e-16 Smith-Waterman score: 443; 30.4% identity (50.4% similar) in 450 aa overlap (1-422:1-392) 10 20 30 40 50 pF1KSD MVMVLSESLSTRGADSIACGTFSRELHTPKKMSQGPTLFSCG-----IMENDRWRDLDR- :. ...:.:. . : . : :: : : . . . .:: . :. :: : . CCDS42 MITLITEQLQKQTLDELKCTRFSISLPLPDHAD----ISNCGNSFQLVSEGASWRGLPHC 10 20 30 40 50 60 70 80 90 100 pF1KSD KCPLQID------QPS-TSIWECLPEKDSSLWHREAVTACAVTSLIKDLSISDHNGNPSA .: : .:: :. : . .: .: . .. : .. : : CCDS42 SCAEFQDSLNFSYHPSGLSLHLRPPSRGNS--PKEQPFSQVLRPEPPD---PEKLPVPPA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD PPSKRQCRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSS :::::.::::: ..: . ::: ::.:::...: .::. : . : .: :: CCDS42 PPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQ--SPPKRVSS 120 130 140 150 160 170 180 190 200 210 pF1KSD FSLPSRANVLSSPCDQAGLHHRFGGQPCQGVP----GSAPCG---QAGDTWSPD---LHP . . .: :: : : :: . : .. .: ::. :.: .: : : : CCDS42 LRF-LQAPSASSQCAPA---HRPYSPPFFSLALAQDSSRPCAASPQSG-SWESDAESLSP 170 180 190 200 210 220 220 230 240 250 260 270 pF1KSD VGGGR-LDLQRSLSCSHEQFSFVEYCPPSANSTPASTPELARRSSGLS---RSRSQPCVL : ..:. ::. . .: ::: :.:::.::: : :: ::::::: : CCDS42 CPPQRRFSLSPSLGPQASRFL------PSARSSPASSPELPWRPRGLRNLPRSRSQPCDL 230 240 250 260 270 280 290 300 310 320 330 pF1KSD NDKKVGVKRRRPEEVQEQRPSLDLAKMAQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNT . .:.:::::. :. .. :::::. :: : . .:. ::. ... . :: CCDS42 DARKTGVKRRHEEDPRRLRPSLDFDKMNQ--KPYSGGLCLQETAREGSSISP-------- 280 290 300 310 320 340 350 360 370 380 390 pF1KSD RAWTALLSASGPGGRTPAGTPVPEPLPPSFDDHLVCQEDLSCEESDSCALDEDCGRRAEP : ... : : :: : :. . . : . .:. : CCDS42 -PW--FMACS------------PPPLSAS------CSPTGGSSQVLSESEEEEEG----- 330 340 350 360 400 410 420 pF1KSD AAAWRDRGAPGNSLCSLD-GELDIEQIEKN :. : .. .::. : :.::.. ::.: CCDS42 AVRWGRQALSKRTLCQRDFGDLDLNLIEEN 370 380 390 >>CCDS75091.1 FAM53A gene_id:152877|Hs108|chr4 (360 aa) initn: 426 init1: 255 opt: 323 Z-score: 307.8 bits: 65.7 E(32554): 8e-11 Smith-Waterman score: 494; 29.8% identity (57.7% similar) in 359 aa overlap (1-345:1-344) 10 20 30 40 50 pF1KSD MVMVLSESLSTRGADSIACGTFSREL-HTPKKMSQGPTLFSCGIMENDRWRDLDRKCPLQ :: ...:.:.... :...: . . : .. . .... :: . ... :. .. :.. CCDS75 MVTLITEKLQSQSLDDLTCKAEAGPLQYSAETLNKSGRLFPLELNDQSPWKVFSGGPPVR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD IDQPSTSIWECLPEKDSSL------WHREAVTACAVTSLIKDLSISDHNGNPSAPPSKRQ . . . :: ... :. .. : . . .. :. .:. .:::.::. CCDS75 SQAATGPDFSFLPGLSAAAHTMGLQWQPQSPRPGAGLGAASTVDPSESTGSSTAPPTKRH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD CRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSSFSLPSR ::::: .:. ::. ::: .::::::: :::: ::::. : .. ... ::. .: CCDS75 CRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGGSATRQGSPGAVLPRSAVWSTGPT 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD ANVLSSPCDQAGLHHRFGGQPCQGVPGSAPCGQAGDTWSPDLHPVGGGRLDLQRSLSCSH . . : . .: : . .: ::.: .... :. .: : :. CCDS75 SPATPRPSSASG---GFVDSS-EGSAGSGPLWCSAESCLPST----------RRRPSLSQ 190 200 210 220 240 250 260 270 280 290 pF1KSD EQFSFVEYCPPSANSTPASTPELARRSSGLSRSRSQPCVLNDKKVGVKRRRPEEVQEQRP :... . : :.:.:.::: :. : :: : :::::::. :. :::: :... :: CCDS75 ERLAGAGTPLPWASSSPTSTPALGGRR-GLLRCRSQPCVLSGKRSRRKRRREEDARWTRP 230 240 250 260 270 280 300 310 320 330 340 pF1KSD SLDLAKMAQ--NC--QTFSSLSCLSAGTED-CGP--QSPFARHVSNTRAWTALLSASGPG :::. ::.: .: . : . :... . :: :: . : : . . .: CCDS75 SLDFLKMTQPHSCARECESRVRGLGVSLQHLSGPSSQSRGSTLNENKTPWFEMEGNLAPE 290 300 310 320 330 340 350 360 370 380 390 400 pF1KSD GRTPAGTPVPEPLPPSFDDHLVCQEDLSCEESDSCALDEDCGRRAEPAAAWRDRGAPGNS CCDS75 DFKKFKKPLLPQLRR 350 360 >>CCDS33939.1 FAM53A gene_id:152877|Hs108|chr4 (398 aa) initn: 529 init1: 279 opt: 323 Z-score: 307.1 bits: 65.8 E(32554): 8.7e-11 Smith-Waterman score: 516; 29.2% identity (55.3% similar) in 432 aa overlap (1-422:1-398) 10 20 30 40 50 pF1KSD MVMVLSESLSTRGADSIACGTFSREL-HTPKKMSQGPTLFSCGIMENDRWRDLDRKCPLQ :: ...:.:.... :...: . . : .. . .... :: . ... :. .. :.. CCDS33 MVTLITEKLQSQSLDDLTCKAEAGPLQYSAETLNKSGRLFPLELNDQSPWKVFSGGPPVR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD IDQPSTSIWECLPEKDSSL------WHREAVTACAVTSLIKDLSISDHNGNPSAPPSKRQ . . . :: ... :. .. : . . .. :. .:. .:::.::. CCDS33 SQAATGPDFSFLPGLSAAAHTMGLQWQPQSPRPGAGLGAASTVDPSESTGSSTAPPTKRH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KSD CRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSSFSLPSR ::::: .:. ::. ::: .::::::: :::: ::::. : .. ... ::. .: CCDS33 CRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGGSATRQGSPGAVLPRSAVWSTGPT 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD ANVLSSPCDQAGLHHRFGGQPCQGVPGSAPCGQAGDTWSPDLHPVGGGRLDLQRSLSCSH . . : . .: : . .: ::.: .... :. .: : :. CCDS33 SPATPRPSSASG---GFVDSS-EGSAGSGPLWCSAESCLPS----------TRRRPSLSQ 190 200 210 220 240 250 260 270 280 290 pF1KSD EQFSFVEYCPPSANSTPASTPELARRSSGLSRSRSQPCVLNDKKVGVKRRRPEEVQEQRP :... . : :.:.:.::: :. : :: : :::::::. :. :::: :... :: CCDS33 ERLAGAGTPLPWASSSPTSTPALGGRR-GLLRCRSQPCVLSGKRSRRKRRREEDARWTRP 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD SLDLAKMAQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNTRAWTALLSASGPG--GRTPA :::. ::.:. .. .:: : .: ..: .:. .: . . :: : CCDS33 SLDFLKMTQTLKNSKSL-CSLNYEDDDEDDTPVKTVLSSPCDSRGLPGITMPGCSQRGLR 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD GTPVPEPLPPSFDDHLVCQEDLSCEESDSCALDEDCGRRAE-PAAAWRDRGAPGNSLCSL .:: : : .. : : . : . .. :... : : : CCDS33 TSPVHPNLWASRES---VTSDGSRRSSGDPRDGDSVGEEGVFPRARW------------- 350 360 370 380 420 pF1KSD DGELDIEQIEKN :::.::::.: CCDS33 --ELDLEQIENN 390 422 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:12:23 2016 done: Thu Nov 3 00:12:24 2016 Total Scan time: 2.710 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]