FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0140, 422 aa 1>>>pF1KSDA0140 422 - 422 aa - 422 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0721+/-0.000294; mu= 10.2957+/- 0.018 mean_var=122.0027+/-24.544, 0's: 0 Z-trim(121.9): 10 B-trim: 635 in 1/53 Lambda= 0.116115 statistics sampled from 39131 (39143) to 39131 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.459), width: 16 Scan time: 8.260 The best scores are: opt bits E(85289) NP_057689 (OMIM: 609372) protein FAM53C [Homo sapi ( 392) 432 82.9 1.6e-15 NP_001129119 (OMIM: 609372) protein FAM53C [Homo s ( 392) 432 82.9 1.6e-15 >>NP_057689 (OMIM: 609372) protein FAM53C [Homo sapiens] (392 aa) initn: 391 init1: 179 opt: 432 Z-score: 399.6 bits: 82.9 E(85289): 1.6e-15 Smith-Waterman score: 443; 30.4% identity (50.4% similar) in 450 aa overlap (1-422:1-392) 10 20 30 40 50 pF1KSD MVMVLSESLSTRGADSIACGTFSRELHTPKKMSQGPTLFSCG-----IMENDRWRDLDR- :. ...:.:. . : . : :: : : . . . .:: . :. :: : . NP_057 MITLITEQLQKQTLDELKCTRFSISLPLPDHAD----ISNCGNSFQLVSEGASWRGLPHC 10 20 30 40 50 60 70 80 90 100 pF1KSD KCPLQID------QPS-TSIWECLPEKDSSLWHREAVTACAVTSLIKDLSISDHNGNPSA .: : .:: :. : . .: .: . .. : .. : : NP_057 SCAEFQDSLNFSYHPSGLSLHLRPPSRGNS--PKEQPFSQVLRPEPPD---PEKLPVPPA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD PPSKRQCRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSS :::::.::::: ..: . ::: ::.:::...: .::. : . : .: :: NP_057 PPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQ--SPPKRVSS 120 130 140 150 160 170 180 190 200 210 pF1KSD FSLPSRANVLSSPCDQAGLHHRFGGQPCQGVP----GSAPCG---QAGDTWSPD---LHP . . .: :: : : :: . : .. .: ::. :.: .: : : : NP_057 LRF-LQAPSASSQCAPA---HRPYSPPFFSLALAQDSSRPCAASPQSG-SWESDAESLSP 170 180 190 200 210 220 220 230 240 250 260 270 pF1KSD VGGGR-LDLQRSLSCSHEQFSFVEYCPPSANSTPASTPELARRSSGLS---RSRSQPCVL : ..:. ::. . .: ::: :.:::.::: : :: ::::::: : NP_057 CPPQRRFSLSPSLGPQASRFL------PSARSSPASSPELPWRPRGLRNLPRSRSQPCDL 230 240 250 260 270 280 290 300 310 320 330 pF1KSD NDKKVGVKRRRPEEVQEQRPSLDLAKMAQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNT . .:.:::::. :. .. :::::. :: : . .:. ::. ... . :: NP_057 DARKTGVKRRHEEDPRRLRPSLDFDKMNQ--KPYSGGLCLQETAREGSSISP-------- 280 290 300 310 320 340 350 360 370 380 390 pF1KSD RAWTALLSASGPGGRTPAGTPVPEPLPPSFDDHLVCQEDLSCEESDSCALDEDCGRRAEP : ... : : :: : :. . . : . .:. : NP_057 -PW--FMACS------------PPPLSAS------CSPTGGSSQVLSESEEEEEG----- 330 340 350 360 400 410 420 pF1KSD AAAWRDRGAPGNSLCSLD-GELDIEQIEKN :. : .. .::. : :.::.. ::.: NP_057 AVRWGRQALSKRTLCQRDFGDLDLNLIEEN 370 380 390 >>NP_001129119 (OMIM: 609372) protein FAM53C [Homo sapie (392 aa) initn: 391 init1: 179 opt: 432 Z-score: 399.6 bits: 82.9 E(85289): 1.6e-15 Smith-Waterman score: 443; 30.4% identity (50.4% similar) in 450 aa overlap (1-422:1-392) 10 20 30 40 50 pF1KSD MVMVLSESLSTRGADSIACGTFSRELHTPKKMSQGPTLFSCG-----IMENDRWRDLDR- :. ...:.:. . : . : :: : : . . . .:: . :. :: : . NP_001 MITLITEQLQKQTLDELKCTRFSISLPLPDHAD----ISNCGNSFQLVSEGASWRGLPHC 10 20 30 40 50 60 70 80 90 100 pF1KSD KCPLQID------QPS-TSIWECLPEKDSSLWHREAVTACAVTSLIKDLSISDHNGNPSA .: : .:: :. : . .: .: . .. : .. : : NP_001 SCAEFQDSLNFSYHPSGLSLHLRPPSRGNS--PKEQPFSQVLRPEPPD---PEKLPVPPA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD PPSKRQCRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGFSTMQRSSS :::::.::::: ..: . ::: ::.:::...: .::. : . : .: :: NP_001 PPSKRHCRSLSVPVDLSRWQPVWRPAPSKLWTPIKHRGSGGGGGPQVPHQ--SPPKRVSS 120 130 140 150 160 170 180 190 200 210 pF1KSD FSLPSRANVLSSPCDQAGLHHRFGGQPCQGVP----GSAPCG---QAGDTWSPD---LHP . . .: :: : : :: . : .. .: ::. :.: .: : : : NP_001 LRF-LQAPSASSQCAPA---HRPYSPPFFSLALAQDSSRPCAASPQSG-SWESDAESLSP 170 180 190 200 210 220 220 230 240 250 260 270 pF1KSD VGGGR-LDLQRSLSCSHEQFSFVEYCPPSANSTPASTPELARRSSGLS---RSRSQPCVL : ..:. ::. . .: ::: :.:::.::: : :: ::::::: : NP_001 CPPQRRFSLSPSLGPQASRFL------PSARSSPASSPELPWRPRGLRNLPRSRSQPCDL 230 240 250 260 270 280 290 300 310 320 330 pF1KSD NDKKVGVKRRRPEEVQEQRPSLDLAKMAQNCQTFSSLSCLSAGTEDCGPQSPFARHVSNT . .:.:::::. :. .. :::::. :: : . .:. ::. ... . :: NP_001 DARKTGVKRRHEEDPRRLRPSLDFDKMNQ--KPYSGGLCLQETAREGSSISP-------- 280 290 300 310 320 340 350 360 370 380 390 pF1KSD RAWTALLSASGPGGRTPAGTPVPEPLPPSFDDHLVCQEDLSCEESDSCALDEDCGRRAEP : ... : : :: : :. . . : . .:. : NP_001 -PW--FMACS------------PPPLSAS------CSPTGGSSQVLSESEEEEEG----- 330 340 350 360 400 410 420 pF1KSD AAAWRDRGAPGNSLCSLD-GELDIEQIEKN :. : .. .::. : :.::.. ::.: NP_001 AVRWGRQALSKRTLCQRDFGDLDLNLIEEN 370 380 390 422 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:12:24 2016 done: Thu Nov 3 00:12:25 2016 Total Scan time: 8.260 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]