FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0141, 515 aa 1>>>pF1KSDA0141 515 - 515 aa - 515 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7686+/-0.000323; mu= 13.1498+/- 0.020 mean_var=125.9209+/-25.627, 0's: 0 Z-trim(119.8): 28 B-trim: 0 in 0/53 Lambda= 0.114294 statistics sampled from 34276 (34304) to 34276 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.402), width: 16 Scan time: 10.480 The best scores are: opt bits E(85289) NP_055588 (OMIM: 615741) death ligand signal enhan ( 515) 3516 590.8 3.2e-168 XP_005268604 (OMIM: 615741) PREDICTED: death ligan ( 515) 3516 590.8 3.2e-168 XP_005268605 (OMIM: 615741) PREDICTED: death ligan ( 515) 3516 590.8 3.2e-168 NP_001136075 (OMIM: 615741) death ligand signal en ( 515) 3516 590.8 3.2e-168 XP_011536017 (OMIM: 615741) PREDICTED: death ligan ( 405) 2651 448.1 2.3e-125 XP_005268609 (OMIM: 615741) PREDICTED: death ligan ( 389) 2644 446.9 5e-125 XP_011536018 (OMIM: 615741) PREDICTED: death ligan ( 286) 1764 301.7 1.9e-81 XP_006714875 (OMIM: 615741) PREDICTED: death ligan ( 260) 1729 295.9 9.6e-80 >>NP_055588 (OMIM: 615741) death ligand signal enhancer (515 aa) initn: 3516 init1: 3516 opt: 3516 Z-score: 3141.0 bits: 590.8 E(85289): 3.2e-168 Smith-Waterman score: 3516; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL 430 440 450 460 470 480 490 500 510 pF1KSD LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG ::::::::::::::::::::::::::::::::::: NP_055 LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG 490 500 510 >>XP_005268604 (OMIM: 615741) PREDICTED: death ligand si (515 aa) initn: 3516 init1: 3516 opt: 3516 Z-score: 3141.0 bits: 590.8 E(85289): 3.2e-168 Smith-Waterman score: 3516; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL 430 440 450 460 470 480 490 500 510 pF1KSD LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG ::::::::::::::::::::::::::::::::::: XP_005 LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG 490 500 510 >>XP_005268605 (OMIM: 615741) PREDICTED: death ligand si (515 aa) initn: 3516 init1: 3516 opt: 3516 Z-score: 3141.0 bits: 590.8 E(85289): 3.2e-168 Smith-Waterman score: 3516; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL 430 440 450 460 470 480 490 500 510 pF1KSD LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG ::::::::::::::::::::::::::::::::::: XP_005 LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG 490 500 510 >>NP_001136075 (OMIM: 615741) death ligand signal enhanc (515 aa) initn: 3516 init1: 3516 opt: 3516 Z-score: 3141.0 bits: 590.8 E(85289): 3.2e-168 Smith-Waterman score: 3516; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KSD MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL 430 440 450 460 470 480 490 500 510 pF1KSD LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG ::::::::::::::::::::::::::::::::::: NP_001 LCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG 490 500 510 >>XP_011536017 (OMIM: 615741) PREDICTED: death ligand si (405 aa) initn: 2700 init1: 2647 opt: 2651 Z-score: 2371.6 bits: 448.1 E(85289): 2.3e-125 Smith-Waterman score: 2651; 97.7% identity (98.5% similar) in 394 aa overlap (1-394:1-394) 10 20 30 40 50 60 pF1KSD MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN :::::::::::::::::::::::. : . .: XP_011 FTKEPYLDEQRAVKYLWLAANNGEEVSCPNAWMCLLDFQNFSPQP 370 380 390 400 430 440 450 460 470 480 pF1KSD EAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAGTSRLPHASSTGNLGL >>XP_005268609 (OMIM: 615741) PREDICTED: death ligand si (389 aa) initn: 2644 init1: 2644 opt: 2644 Z-score: 2365.6 bits: 446.9 E(85289): 5e-125 Smith-Waterman score: 2644; 100.0% identity (100.0% similar) in 383 aa overlap (1-383:1-383) 10 20 30 40 50 60 pF1KSD MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQAADSGLREAQAFLGVL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGN ::::::::::::::::::::::: XP_005 FTKEPYLDEQRAVKYLWLAANNGPRGPAT 370 380 >>XP_011536018 (OMIM: 615741) PREDICTED: death ligand si (286 aa) initn: 1761 init1: 1761 opt: 1764 Z-score: 1583.3 bits: 301.7 E(85289): 1.9e-81 Smith-Waterman score: 1764; 97.3% identity (98.5% similar) in 260 aa overlap (1-260:1-259) 10 20 30 40 50 60 pF1KSD MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MWRLPGLLGRALPRTLGPSLWRVTPKSTSPDGPQTTSSTLLVPVPNLDRSGPHGPGTSGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRSHGWKDAFQWMSSRVSPNTLWDAISWGTLAVLALQLARQIHFQASLPAGPQRVEHCSW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSPLDRFFSSPLWHPCSSLRQHILPSPDGPAPRHTGLREPRLGQEEASAQPRNFSHNSLR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GARPQDPSEEGPGDFGFLHASSSIESEAKPAQPQPTGEKEQDKSKTLSLEEAVTSIQQLF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD QLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGLCHEHGRGTPRDISKA ::::::::::: . . .:: XP_011 QLSVSIAFNFL-VPVLGTGDTVIYKTKSLFSGSRKTIIEKQKENFRC 250 260 270 280 >>XP_006714875 (OMIM: 615741) PREDICTED: death ligand si (260 aa) initn: 1729 init1: 1729 opt: 1729 Z-score: 1552.6 bits: 295.9 E(85289): 9.6e-80 Smith-Waterman score: 1729; 100.0% identity (100.0% similar) in 260 aa overlap (256-515:1-260) 230 240 250 260 270 280 pF1KSD TLSLEEAVTSIQQLFQLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYSKAQYNAGL :::::::::::::::::::::::::::::: XP_006 MKSGDHTAAFSYFQKAAARGYSKAQYNAGL 10 20 30 290 300 310 320 330 340 pF1KSD CHEHGRGTPRDISKAVLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CHEHGRGTPRDISKAVLYYQLAASQGHSLAQYRYARCLLRDPASSWNPERQRAVSLLKQA 40 50 60 70 80 90 350 360 370 380 390 400 pF1KSD ADSGLREAQAFLGVLFTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADSGLREAQAFLGVLFTKEPYLDEQRAVKYLWLAANNGDSQSRYHLGICYEKGLGVQRNL 100 110 120 130 140 150 410 420 430 440 450 460 pF1KSD GEALRCYQQSAALGNEAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GEALRCYQQSAALGNEAAQERLRALFSMGAAAPGPSDLTVTGLKSFSSPSLCSLNTLLAG 160 170 180 190 200 210 470 480 490 500 510 pF1KSD TSRLPHASSTGNLGLLCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSRLPHASSTGNLGLLCRSGHLGASLEASSRAIPPHPYPLERSVVRLGFG 220 230 240 250 260 515 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:13:03 2016 done: Thu Nov 3 00:13:04 2016 Total Scan time: 10.480 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]