FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0146, 915 aa 1>>>pF1KSDA0146 915 - 915 aa - 915 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4135+/-0.000367; mu= 22.0929+/- 0.023 mean_var=93.2905+/-17.992, 0's: 0 Z-trim(115.7): 41 B-trim: 0 in 0/52 Lambda= 0.132787 statistics sampled from 26279 (26320) to 26279 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.309), width: 16 Scan time: 11.300 The best scores are: opt bits E(85289) NP_001073863 (OMIM: 615384) DNA repair-scaffolding ( 915) 6118 1182.9 0 XP_011515799 (OMIM: 615384) PREDICTED: DNA repair- ( 895) 5825 1126.8 0 XP_005251246 (OMIM: 615384) PREDICTED: DNA repair- ( 883) 5713 1105.3 0 XP_016868757 (OMIM: 615384) PREDICTED: DNA repair- ( 936) 5713 1105.4 0 XP_006716506 (OMIM: 615384) PREDICTED: DNA repair- ( 855) 5674 1097.8 0 NP_001269845 (OMIM: 615384) DNA repair-scaffolding ( 845) 5531 1070.4 0 XP_005251250 (OMIM: 615384) PREDICTED: DNA repair- ( 815) 5438 1052.6 0 XP_016868760 (OMIM: 615384) PREDICTED: DNA repair- ( 876) 5269 1020.3 0 NP_001269848 (OMIM: 615384) DNA repair-scaffolding ( 876) 5269 1020.3 0 XP_005251248 (OMIM: 615384) PREDICTED: DNA repair- ( 848) 5203 1007.6 0 XP_016868766 (OMIM: 615384) PREDICTED: DNA repair- ( 755) 4994 967.5 0 XP_011515802 (OMIM: 615384) PREDICTED: DNA repair- ( 875) 4964 961.8 0 XP_005251252 (OMIM: 615384) PREDICTED: DNA repair- ( 751) 4946 958.3 0 XP_016868767 (OMIM: 615384) PREDICTED: DNA repair- ( 751) 4946 958.3 0 XP_016868759 (OMIM: 615384) PREDICTED: DNA repair- ( 896) 4559 884.3 0 XP_016868761 (OMIM: 615384) PREDICTED: DNA repair- ( 791) 4548 882.1 0 XP_016868764 (OMIM: 615384) PREDICTED: DNA repair- ( 770) 4541 880.8 0 XP_016868763 (OMIM: 615384) PREDICTED: DNA repair- ( 772) 4541 880.8 0 XP_016868765 (OMIM: 615384) PREDICTED: DNA repair- ( 762) 4540 880.6 0 XP_005251255 (OMIM: 615384) PREDICTED: DNA repair- ( 665) 4413 856.2 0 XP_006716507 (OMIM: 615384) PREDICTED: DNA repair- ( 665) 4413 856.2 0 XP_016868758 (OMIM: 615384) PREDICTED: DNA repair- ( 916) 4299 834.5 0 XP_016868773 (OMIM: 615384) PREDICTED: DNA repair- ( 651) 4266 828.0 0 XP_016868772 (OMIM: 615384) PREDICTED: DNA repair- ( 664) 4260 826.9 0 XP_016868768 (OMIM: 615384) PREDICTED: DNA repair- ( 717) 4260 826.9 0 XP_005251256 (OMIM: 615384) PREDICTED: DNA repair- ( 604) 4064 789.3 0 XP_016868771 (OMIM: 615384) PREDICTED: DNA repair- ( 684) 4031 783.0 0 XP_016868774 (OMIM: 615384) PREDICTED: DNA repair- ( 633) 4008 778.6 0 XP_016868770 (OMIM: 615384) PREDICTED: DNA repair- ( 686) 4008 778.6 0 XP_016868769 (OMIM: 615384) PREDICTED: DNA repair- ( 686) 4008 778.6 0 XP_016868777 (OMIM: 615384) PREDICTED: DNA repair- ( 559) 3701 719.7 9.7e-207 XP_016868775 (OMIM: 615384) PREDICTED: DNA repair- ( 625) 3659 711.7 2.8e-204 XP_016868779 (OMIM: 615384) PREDICTED: DNA repair- ( 504) 3384 658.9 1.7e-188 XP_016868780 (OMIM: 615384) PREDICTED: DNA repair- ( 499) 3347 651.8 2.3e-186 XP_016868762 (OMIM: 615384) PREDICTED: DNA repair- ( 779) 3300 643.0 1.6e-183 XP_016868778 (OMIM: 615384) PREDICTED: DNA repair- ( 527) 3296 642.1 2.1e-183 XP_016868776 (OMIM: 615384) PREDICTED: DNA repair- ( 580) 3296 642.1 2.3e-183 XP_011515809 (OMIM: 615384) PREDICTED: DNA repair- ( 390) 2616 511.7 2.8e-144 >>NP_001073863 (OMIM: 615384) DNA repair-scaffolding pro (915 aa) initn: 6118 init1: 6118 opt: 6118 Z-score: 6332.3 bits: 1182.9 E(85289): 0 Smith-Waterman score: 6118; 100.0% identity (100.0% similar) in 915 aa overlap (1-915:1-915) 10 20 30 40 50 60 pF1KSD MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAHPTSCIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAHPTSCIGL 850 860 870 880 890 900 910 pF1KSD EEIELLSAGGASAEH ::::::::::::::: NP_001 EEIELLSAGGASAEH 910 >>XP_011515799 (OMIM: 615384) PREDICTED: DNA repair-scaf (895 aa) initn: 5865 init1: 5824 opt: 5825 Z-score: 6029.0 bits: 1126.8 E(85289): 0 Smith-Waterman score: 5825; 99.1% identity (99.4% similar) in 879 aa overlap (1-876:1-879) 10 20 30 40 50 60 pF1KSD MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR 790 800 810 820 830 840 850 860 870 880 890 pF1KSD SRPQCRVKVKLLQRSISSLLRFAAGEDGSYE---VKSVLGKEVGLLNCFVQSVTAHPTSC :::::::::::::::::::::::::::: : ..:.: XP_011 SRPQCRVKVKLLQRSISSLLRFAAGEDGLYSQWLIRSLLRIWKEADRRWVPEGPG 850 860 870 880 890 900 910 pF1KSD IGLEEIELLSAGGASAEH >>XP_005251246 (OMIM: 615384) PREDICTED: DNA repair-scaf (883 aa) initn: 5713 init1: 5713 opt: 5713 Z-score: 5913.1 bits: 1105.3 E(85289): 0 Smith-Waterman score: 5713; 99.6% identity (99.8% similar) in 854 aa overlap (1-854:1-854) 10 20 30 40 50 60 pF1KSD MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAHPTSCIGL ::::::::::. : XP_005 SRPQCRVKVKVGARPEHARTPSSLQHSEAVAAQHFLPAEVCRR 850 860 870 880 >>XP_016868757 (OMIM: 615384) PREDICTED: DNA repair-scaf (936 aa) initn: 5752 init1: 5711 opt: 5713 Z-score: 5912.8 bits: 1105.4 E(85289): 0 Smith-Waterman score: 5713; 99.6% identity (99.8% similar) in 854 aa overlap (1-854:1-854) 10 20 30 40 50 60 pF1KSD MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD SRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAHPTSCIGL ::::::::::. : XP_016 SRPQCRVKVKVGARPEHARTPSSLQHSEELRSEECPRKGSGVVKLFCPVRNRPPDQLHWI 850 860 870 880 890 900 >>XP_006716506 (OMIM: 615384) PREDICTED: DNA repair-scaf (855 aa) initn: 5674 init1: 5674 opt: 5674 Z-score: 5873.0 bits: 1097.8 E(85289): 0 Smith-Waterman score: 5674; 100.0% identity (100.0% similar) in 852 aa overlap (64-915:4-855) 40 50 60 70 80 90 pF1KSD AGLRTAGAAASLSEAWLRCGEGFQNTSGNPSLTAEEKTITEKHLELCPRPKQETTTSKST :::::::::::::::::::::::::::::: XP_006 MAQSLTAEEKTITEKHLELCPRPKQETTTSKST 10 20 30 100 110 120 130 140 150 pF1KSD SGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEIS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD DCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD SDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRE 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD RSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVA 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD PRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKED 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD SEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQ 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD RIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAG 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD TRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTL 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD WPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRC 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD LRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKT 580 590 600 610 620 630 700 710 720 730 740 750 pF1KSD LLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGA 640 650 660 670 680 690 760 770 780 790 800 810 pF1KSD SSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRG 700 710 720 730 740 750 820 830 840 850 860 870 pF1KSD AFSCGDCSRVVTSPVLKRHLQVFLDCRSRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AFSCGDCSRVVTSPVLKRHLQVFLDCRSRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVK 760 770 780 790 800 810 880 890 900 910 pF1KSD SVLGKEVGLLNCFVQSVTAHPTSCIGLEEIELLSAGGASAEH :::::::::::::::::::::::::::::::::::::::::: XP_006 SVLGKEVGLLNCFVQSVTAHPTSCIGLEEIELLSAGGASAEH 820 830 840 850 >>NP_001269845 (OMIM: 615384) DNA repair-scaffolding pro (845 aa) initn: 5531 init1: 5531 opt: 5531 Z-score: 5725.0 bits: 1070.4 E(85289): 0 Smith-Waterman score: 5531; 99.8% identity (100.0% similar) in 832 aa overlap (84-915:14-845) 60 70 80 90 100 110 pF1KSD EGFQNTSGNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDK ..:::::::::::::::::::::::::::: NP_001 MAQVWRRVSEHFWESETTTSKSTSGLTDITWSSSGSDLSDEDK 10 20 30 40 120 130 140 150 160 170 pF1KSD TLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSEL 50 60 70 80 90 100 180 190 200 210 220 230 pF1KSD PKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTET 110 120 130 140 150 160 240 250 260 270 280 290 pF1KSD ILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSG 170 180 190 200 210 220 300 310 320 330 340 350 pF1KSD RKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLR 230 240 250 260 270 280 360 370 380 390 400 410 pF1KSD GRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSIS 290 300 310 320 330 340 420 430 440 450 460 470 pF1KSD LAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQG 350 360 370 380 390 400 480 490 500 510 520 530 pF1KSD AASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLE 410 420 430 440 450 460 540 550 560 570 580 590 pF1KSD FTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIK 470 480 490 500 510 520 600 610 620 630 640 650 pF1KSD THLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATV 530 540 550 560 570 580 660 670 680 690 700 710 pF1KSD IYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALA 590 600 610 620 630 640 720 730 740 750 760 770 pF1KSD GAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPV 650 660 670 680 690 700 780 790 800 810 820 830 pF1KSD NSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHL 710 720 730 740 750 760 840 850 860 870 880 890 pF1KSD QVFLDCRSRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVFLDCRSRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAH 770 780 790 800 810 820 900 910 pF1KSD PTSCIGLEEIELLSAGGASAEH :::::::::::::::::::::: NP_001 PTSCIGLEEIELLSAGGASAEH 830 840 >>XP_005251250 (OMIM: 615384) PREDICTED: DNA repair-scaf (815 aa) initn: 5438 init1: 5438 opt: 5438 Z-score: 5628.9 bits: 1052.6 E(85289): 0 Smith-Waterman score: 5438; 100.0% identity (100.0% similar) in 812 aa overlap (1-812:1-812) 10 20 30 40 50 60 pF1KSD MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR :::::::::::::::::::::::::::::::: XP_005 GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRATK 790 800 810 850 860 870 880 890 900 pF1KSD SRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVKSVLGKEVGLLNCFVQSVTAHPTSCIGL >>XP_016868760 (OMIM: 615384) PREDICTED: DNA repair-scaf (876 aa) initn: 5308 init1: 5267 opt: 5269 Z-score: 5453.5 bits: 1020.3 E(85289): 0 Smith-Waterman score: 5269; 99.6% identity (99.7% similar) in 791 aa overlap (64-854:4-794) 40 50 60 70 80 90 pF1KSD AGLRTAGAAASLSEAWLRCGEGFQNTSGNPSLTAEEKTITEKHLELCPRPKQETTTSKST :::::::::::::::::::::::::::::: XP_016 MAQSLTAEEKTITEKHLELCPRPKQETTTSKST 10 20 30 100 110 120 130 140 150 pF1KSD SGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEIS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD DCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD SDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRE 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD RSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVA 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD PRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKED 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD SEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQ 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD RIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAG 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD TRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTL 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD WPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRC 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD LRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKT 580 590 600 610 620 630 700 710 720 730 740 750 pF1KSD LLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGA 640 650 660 670 680 690 760 770 780 790 800 810 pF1KSD SSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRG 700 710 720 730 740 750 820 830 840 850 860 870 pF1KSD AFSCGDCSRVVTSPVLKRHLQVFLDCRSRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVK :::::::::::::::::::::::::::::::::::::. : XP_016 AFSCGDCSRVVTSPVLKRHLQVFLDCRSRPQCRVKVKVGARPEHARTPSSLQHSEELRSE 760 770 780 790 800 810 880 890 900 910 pF1KSD SVLGKEVGLLNCFVQSVTAHPTSCIGLEEIELLSAGGASAEH XP_016 ECPRKGSGVVKLFCPVRNRPPDQLHWIGGNRASECRRGLCRTLAVAAGSVNFAMWLQGWW 820 830 840 850 860 870 >>NP_001269848 (OMIM: 615384) DNA repair-scaffolding pro (876 aa) initn: 5308 init1: 5267 opt: 5269 Z-score: 5453.5 bits: 1020.3 E(85289): 0 Smith-Waterman score: 5269; 99.6% identity (99.7% similar) in 791 aa overlap (64-854:4-794) 40 50 60 70 80 90 pF1KSD AGLRTAGAAASLSEAWLRCGEGFQNTSGNPSLTAEEKTITEKHLELCPRPKQETTTSKST :::::::::::::::::::::::::::::: NP_001 MAQSLTAEEKTITEKHLELCPRPKQETTTSKST 10 20 30 100 110 120 130 140 150 pF1KSD SGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLTDITWSSSGSDLSDEDKTLSQLQRDELQFIDWEIDSDRAEASDCDEFEDDEGAVEIS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD DCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCASCASNQSLTSDEKLSELPKPSSIEILEYSSDSEKEDDLENVLLIDSESPHKYHVQFA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD SDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDARQIMERLIDPRTKSTETILHTPQKPTAKFPRTPENSAKKKLLRGGLAERLNGLQNRE 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD RSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSAISLWRHQCISYQKTLSGRKSGVLTVKILELHEECAMQVAMCEQLLGSPATSSSQSVA 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD PRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRPGAGLKVLFTKETAGYLRGRPQDTVRIFPPWQKLIIPSGSCPVILNTYFCEKVVAKED 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD SEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEKTCEVYCPDIPLPRRSISLAQMFVIKGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQ 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD RIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIPTSTPLRDSLLDVVESQGAASWPGAGVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAG 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD TRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRACLLVQDACGMFGEVHLEFTMSKARQLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTL 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD WPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WPPAIPLKTPGRDQPCEEIKTHLPPPALCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRC 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD LRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDILQMNDLGTRCSFYATVIYQKPQLKSLLLLEQREIWLLVTDVTLQTKEERDPRLPKT 580 590 600 610 620 630 700 710 720 730 740 750 pF1KSD LLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVYVAPLCVLGSEVLEALAGAAPHSLFFKDALRDQGRIVCAERTVLLLQKPLLSVVSGA 640 650 660 670 680 690 760 770 780 790 800 810 pF1KSD SSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCELPGPVMLDSLDSATPVNSICSVQGTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRG 700 710 720 730 740 750 820 830 840 850 860 870 pF1KSD AFSCGDCSRVVTSPVLKRHLQVFLDCRSRPQCRVKVKLLQRSISSLLRFAAGEDGSYEVK :::::::::::::::::::::::::::::::::::::. : NP_001 AFSCGDCSRVVTSPVLKRHLQVFLDCRSRPQCRVKVKVGARPEHARTPSSLQHSEELRSE 760 770 780 790 800 810 880 890 900 910 pF1KSD SVLGKEVGLLNCFVQSVTAHPTSCIGLEEIELLSAGGASAEH NP_001 ECPRKGSGVVKLFCPVRNRPPDQLHWIGGNRASECRRGLCRTLAVAAGSVNFAMWLQGWW 820 830 840 850 860 870 >>XP_005251248 (OMIM: 615384) PREDICTED: DNA repair-scaf (848 aa) initn: 5203 init1: 5203 opt: 5203 Z-score: 5385.4 bits: 1007.6 E(85289): 0 Smith-Waterman score: 5203; 100.0% identity (100.0% similar) in 780 aa overlap (1-780:1-780) 10 20 30 40 50 60 pF1KSD MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPRGSRARGSKRKRSWNTECPSFPGERPLQVRRAGLRTAGAAASLSEAWLRCGEGFQNTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNPSLTAEEKTITEKHLELCPRPKQETTTSKSTSGLTDITWSSSGSDLSDEDKTLSQLQR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DELQFIDWEIDSDRAEASDCDEFEDDEGAVEISDCASCASNQSLTSDEKLSELPKPSSIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILEYSSDSEKEDDLENVLLIDSESPHKYHVQFASDARQIMERLIDPRTKSTETILHTPQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTAKFPRTPENSAKKKLLRGGLAERLNGLQNRERSAISLWRHQCISYQKTLSGRKSGVLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKILELHEECAMQVAMCEQLLGSPATSSSQSVAPRPGAGLKVLFTKETAGYLRGRPQDTV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIFPPWQKLIIPSGSCPVILNTYFCEKVVAKEDSEKTCEVYCPDIPLPRRSISLAQMFVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGLTNNSPEIQVVCSGVATTGTAWTHGHKEAKQRIPTSTPLRDSLLDVVESQGAASWPGA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVRVVVQRVYSLPSRDSTRGQQGASSGHTDPAGTRACLLVQDACGMFGEVHLEFTMSKAR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLEGKSCSLVGMKVLQKVTRGRTAGIFSLIDTLWPPAIPLKTPGRDQPCEEIKTHLPPPA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LCYILTAHPNLGQIDIIDEDPIYKLYQPPVTRCLRDILQMNDLGTRCSFYATVIYQKPQL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSLLLLEQREIWLLVTDVTLQTKEERDPRLPKTLLVYVAPLCVLGSEVLEALAGAAPHSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFKDALRDQGRIVCAERTVLLLQKPLLSVVSGASSCELPGPVMLDSLDSATPVNSICSVQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD GTVVGVDESTAFSWPVCDMCGNGRLEQRPEDRGAFSCGDCSRVVTSPVLKRHLQVFLDCR XP_005 ELRSEECPRKGSGVVKLFCPVRNRPPDQLHWIGGNRASECRRGLCRTLAVAAGSVNFAMW 790 800 810 820 830 840 915 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:14:29 2016 done: Thu Nov 3 00:14:30 2016 Total Scan time: 11.300 Total Display time: 0.220 Function used was FASTA [36.3.4 Apr, 2011]