FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0155, 1173 aa 1>>>pF1KSDA0155 1173 - 1173 aa - 1173 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.6125+/-0.000554; mu= -11.4873+/- 0.035 mean_var=423.1457+/-84.876, 0's: 0 Z-trim(119.2): 41 B-trim: 1162 in 1/55 Lambda= 0.062349 statistics sampled from 33019 (33067) to 33019 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.388), width: 16 Scan time: 14.550 The best scores are: opt bits E(85289) NP_055448 (OMIM: 609366) RNA polymerase-associated (1173) 7744 712.2 4.8e-204 NP_001333208 (OMIM: 609366) RNA polymerase-associa (1149) 5511 511.3 1.4e-143 >>NP_055448 (OMIM: 609366) RNA polymerase-associated pro (1173 aa) initn: 7744 init1: 7744 opt: 7744 Z-score: 3784.3 bits: 712.2 E(85289): 4.8e-204 Smith-Waterman score: 7744; 100.0% identity (100.0% similar) in 1173 aa overlap (1-1173:1-1173) 10 20 30 40 50 60 pF1KSD MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD TYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD NAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD KKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDN 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KSD EGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD ::::::::::::::::::::::::::::::::: NP_055 EGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1150 1160 1170 >>NP_001333208 (OMIM: 609366) RNA polymerase-associated (1149 aa) initn: 5747 init1: 5316 opt: 5511 Z-score: 2698.8 bits: 511.3 E(85289): 1.4e-143 Smith-Waterman score: 7536; 98.0% identity (98.0% similar) in 1173 aa overlap (1-1173:1-1149) 10 20 30 40 50 60 pF1KSD MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD TYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD LYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD NAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERE ::::::::::: ::::::::::::::::::::::::: NP_001 NAVKELELAHR------------------------QCSDLLSQAQYHVARARKQDEEERE 790 800 810 850 860 870 880 890 900 pF1KSD LRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKE 820 830 840 850 860 870 910 920 930 940 950 960 pF1KSD KKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKR 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KSD RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KSD SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KSD SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDN 1060 1070 1080 1090 1100 1110 1150 1160 1170 pF1KSD EGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD ::::::::::::::::::::::::::::::::: NP_001 EGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1120 1130 1140 1173 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:19:29 2016 done: Thu Nov 3 00:19:31 2016 Total Scan time: 14.550 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]