FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0161, 292 aa 1>>>pF1KSDA0161 292 - 292 aa - 292 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4325+/-0.000383; mu= 17.3457+/- 0.024 mean_var=126.9826+/-26.018, 0's: 0 Z-trim(117.2): 97 B-trim: 1355 in 2/50 Lambda= 0.113816 statistics sampled from 28953 (29057) to 28953 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.341), width: 16 Scan time: 6.030 The best scores are: opt bits E(85289) NP_001120833 (OMIM: 610872) E3 ubiquitin-protein l ( 587) 450 85.1 3.5e-16 NP_001287755 (OMIM: 610872) E3 ubiquitin-protein l ( 731) 450 85.2 4e-16 XP_011519741 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 465) 389 75.0 3.1e-13 XP_011519740 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 498) 389 75.0 3.2e-13 NP_005735 (OMIM: 605624) E3 ubiquitin-protein liga ( 557) 389 75.1 3.5e-13 XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 380 73.4 8e-13 XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 380 73.4 8e-13 XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 380 73.5 8.1e-13 XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 380 73.5 8.1e-13 XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 380 73.5 8.1e-13 XP_016861027 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 380 73.5 8.1e-13 XP_011531577 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 380 73.5 8.1e-13 XP_016861021 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 380 73.5 8.9e-13 XP_016861020 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 380 73.5 8.9e-13 NP_006312 (OMIM: 605615) E3 ubiquitin-protein liga ( 493) 380 73.5 8.9e-13 NP_001304262 (OMIM: 605615) E3 ubiquitin-protein l ( 493) 380 73.5 8.9e-13 NP_001304263 (OMIM: 605615) E3 ubiquitin-protein l ( 351) 362 70.4 5.6e-12 XP_006710421 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 588) 338 66.7 1.2e-10 XP_006710420 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 688) 338 66.8 1.3e-10 NP_699172 (OMIM: 610872) E3 ubiquitin-protein liga ( 732) 338 66.9 1.4e-10 XP_006710419 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 732) 338 66.9 1.4e-10 XP_011531575 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 432) 334 65.9 1.5e-10 XP_011531572 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 334 65.9 1.6e-10 XP_016861022 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 334 65.9 1.6e-10 XP_016861023 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 334 65.9 1.6e-10 XP_016861024 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 334 65.9 1.6e-10 XP_011531573 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 334 65.9 1.6e-10 XP_011531570 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 334 66.0 1.7e-10 XP_011531569 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 334 66.0 1.7e-10 XP_011531568 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 334 66.0 1.7e-10 XP_011531567 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 334 66.0 1.7e-10 XP_016867854 (OMIM: 212840,609948) PREDICTED: E3 u ( 488) 331 65.5 2.3e-10 XP_011513738 (OMIM: 212840,609948) PREDICTED: E3 u ( 488) 331 65.5 2.3e-10 XP_016867852 (OMIM: 212840,609948) PREDICTED: E3 u ( 866) 331 65.8 3.4e-10 NP_996999 (OMIM: 212840,609948) E3 ubiquitin-prote ( 866) 331 65.8 3.4e-10 XP_005249842 (OMIM: 212840,609948) PREDICTED: E3 u ( 923) 331 65.8 3.5e-10 NP_996994 (OMIM: 212840,609948) E3 ubiquitin-prote ( 923) 331 65.8 3.5e-10 XP_016868793 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784) 330 65.6 3.5e-10 XP_011515258 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784) 330 65.6 3.5e-10 XP_005250910 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 330 65.6 3.7e-10 XP_016868792 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 330 65.6 3.7e-10 NP_001267468 (OMIM: 607119) E3 ubiquitin-protein l ( 838) 330 65.6 3.7e-10 XP_016868791 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 330 65.6 3.7e-10 NP_904355 (OMIM: 607119) E3 ubiquitin-protein liga ( 838) 330 65.6 3.7e-10 NP_056250 (OMIM: 607119) E3 ubiquitin-protein liga ( 838) 330 65.6 3.7e-10 XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834) 311 62.9 5.2e-09 XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 is (1909) 311 63.0 5.3e-09 XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 is (2095) 311 63.0 5.6e-09 XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 is (2339) 311 63.1 6e-09 XP_011512727 (OMIM: 607489) PREDICTED: cullin-9 is (2456) 311 63.1 6.2e-09 >>NP_001120833 (OMIM: 610872) E3 ubiquitin-protein ligas (587 aa) initn: 325 init1: 141 opt: 450 Z-score: 411.6 bits: 85.1 E(85289): 3.5e-16 Smith-Waterman score: 450; 30.4% identity (57.9% similar) in 273 aa overlap (18-273:117-376) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCL : : ::: . : :. . .: : :: NP_001 EAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCL 90 100 110 120 130 140 50 60 70 80 90 100 pF1KSD KQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDP ..:..: :.:. .. ::::. : .. :. ..:. ..: .:..:......: . :: NP_001 RHYLRLEISES-RVPISCPE--CSER--LNPHDIRLLLADPPLMHKYEEFMLRRYLASDP 150 160 170 180 190 200 110 120 130 140 150 pF1KSD -CRTWCPASTC-QAVCQLQDVGLQTPQPVQCK--ACRMEFCSTCKASWHPGQGCP----- :: :::: : :: : . . :. .:. ::: :: :::.: : NP_001 DCR-WCPAPDCGYAVIAY---GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQ 210 220 230 240 250 160 170 180 190 200 210 pF1KSD ETMPITFLPGETSA-AFKMEEDDAPIKRCPKCKVYIER--DEGCAQMMCKNCKHAFCWYC ... . .::. .. .: :: ::.:..:: . : .: .: : : ::: : NP_001 RAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLC 260 270 280 290 300 310 220 230 240 250 260 270 pF1KSD LESLDDDFLLIHY-DKGPCR--NKLGHSRAS-VIWHRTQVVGIFAGFGLLLLVASPFLLL .. ..: .:: . . : .: :: . ..:. ..: .:..:. .: : ... NP_001 MKEISD----LHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVI 320 330 340 350 360 370 280 290 pF1KSD ATPFVLCCKCKCSKGDDDPLPT . : NP_001 GIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGIGVPIMLAYVYG 380 390 400 410 420 430 >>NP_001287755 (OMIM: 610872) E3 ubiquitin-protein ligas (731 aa) initn: 325 init1: 141 opt: 450 Z-score: 410.5 bits: 85.2 E(85289): 4e-16 Smith-Waterman score: 450; 30.4% identity (57.9% similar) in 273 aa overlap (18-273:117-376) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCL : : ::: . : :. . .: : :: NP_001 EAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCL 90 100 110 120 130 140 50 60 70 80 90 100 pF1KSD KQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDP ..:..: :.:. .. ::::. : .. :. ..:. ..: .:..:......: . :: NP_001 RHYLRLEISES-RVPISCPE--CSER--LNPHDIRLLLADPPLMHKYEEFMLRRYLASDP 150 160 170 180 190 200 110 120 130 140 150 pF1KSD -CRTWCPASTC-QAVCQLQDVGLQTPQPVQCK--ACRMEFCSTCKASWHPGQGCP----- :: :::: : :: : . . :. .:. ::: :: :::.: : NP_001 DCR-WCPAPDCGYAVIAY---GCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQ 210 220 230 240 250 160 170 180 190 200 210 pF1KSD ETMPITFLPGETSA-AFKMEEDDAPIKRCPKCKVYIER--DEGCAQMMCKNCKHAFCWYC ... . .::. .. .: :: ::.:..:: . : .: .: : : ::: : NP_001 RAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLC 260 270 280 290 300 310 220 230 240 250 260 270 pF1KSD LESLDDDFLLIHY-DKGPCR--NKLGHSRAS-VIWHRTQVVGIFAGFGLLLLVASPFLLL .. ..: .:: . . : .: :: . ..:. ..: .:..:. .: : ... NP_001 MKEISD----LHYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVI 320 330 340 350 360 370 280 290 pF1KSD ATPFVLCCKCKCSKGDDDPLPT . : NP_001 GIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGIGVPIMLAYVYG 380 390 400 410 420 430 >>XP_011519741 (OMIM: 605624) PREDICTED: E3 ubiquitin-pr (465 aa) initn: 303 init1: 116 opt: 389 Z-score: 358.6 bits: 75.0 E(85289): 3.1e-13 Smith-Waterman score: 389; 31.5% identity (55.2% similar) in 203 aa overlap (20-215:94-284) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQ :..: .:: .: . .: :: : .. XP_011 KLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSE 70 80 90 100 110 120 50 60 70 80 90 100 pF1KSD YVEL-LIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPC :. ...::. .:::: .: ...: . ... ... .:..: . : . XP_011 YLTTKIMEEGMGQTISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRL 130 140 150 160 170 180 110 120 130 140 150 160 pF1KSD RTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCP---ETMPITF :::: :. : ..: .::.:: : .:: .: .:: : . . XP_011 LKWCPAPDCHHVVKVQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCD 190 200 210 220 230 170 180 190 200 210 220 pF1KSD LPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKN--CKHAFCWYCLESLDDDF .::: . : :.::::.: ::.: :: .:.:.: :: ::: :: XP_011 DDSETSNWIA-----ANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHG 240 250 260 270 280 290 230 240 250 260 270 280 pF1KSD LLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKC XP_011 SAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKME 300 310 320 330 340 350 >>XP_011519740 (OMIM: 605624) PREDICTED: E3 ubiquitin-pr (498 aa) initn: 303 init1: 116 opt: 389 Z-score: 358.3 bits: 75.0 E(85289): 3.2e-13 Smith-Waterman score: 389; 31.5% identity (55.2% similar) in 203 aa overlap (20-215:127-317) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQ :..: .:: .: . .: :: : .. XP_011 KLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSE 100 110 120 130 140 150 50 60 70 80 90 100 pF1KSD YVEL-LIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPC :. ...::. .:::: .: ...: . ... ... .:..: . : . XP_011 YLTTKIMEEGMGQTISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRL 160 170 180 190 200 210 110 120 130 140 150 160 pF1KSD RTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCP---ETMPITF :::: :. : ..: .::.:: : .:: .: .:: : . . XP_011 LKWCPAPDCHHVVKVQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCD 220 230 240 250 260 170 180 190 200 210 220 pF1KSD LPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKN--CKHAFCWYCLESLDDDF .::: . : :.::::.: ::.: :: .:.:.: :: ::: :: XP_011 DDSETSNWIA-----ANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHG 270 280 290 300 310 320 230 240 250 260 270 280 pF1KSD LLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKC XP_011 SAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKME 330 340 350 360 370 380 >>NP_005735 (OMIM: 605624) E3 ubiquitin-protein ligase A (557 aa) initn: 303 init1: 116 opt: 389 Z-score: 357.7 bits: 75.1 E(85289): 3.5e-13 Smith-Waterman score: 389; 31.5% identity (55.2% similar) in 203 aa overlap (20-215:186-376) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQ :..: .:: .: . .: :: : .. NP_005 KLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGL-ECGHKFCMQCWSE 160 170 180 190 200 210 50 60 70 80 90 100 pF1KSD YVEL-LIKEGLETAISCPDAACPKQGHLQENEIECMVA-AEIMQRYKKLQFEREVLFDPC :. ...::. .:::: .: ...: . ... ... .:..: . : . NP_005 YLTTKIMEEGMGQTISCPAHGCDIL--VDDNTVMRLITDSKVKLKYQHLITNSFVECNRL 220 230 240 250 260 270 110 120 130 140 150 160 pF1KSD RTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCP---ETMPITF :::: :. : ..: .::.:: : .:: .: .:: : . . NP_005 LKWCPAPDCHHVVKVQ---YPDAKPVRCK-CGRQFCFNCGENWHDPVKCKWLKKWIKKCD 280 290 300 310 320 170 180 190 200 210 220 pF1KSD LPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKN--CKHAFCWYCLESLDDDF .::: . : :.::::.: ::.: :: .:.:.: :: ::: :: NP_005 DDSETSNWIA-----ANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHG 330 340 350 360 370 380 230 240 250 260 270 280 pF1KSD LLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKC NP_005 SAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKME 390 400 410 420 430 440 >>XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr (409 aa) initn: 339 init1: 184 opt: 380 Z-score: 351.2 bits: 73.4 E(85289): 8e-13 Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:51-243) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL : : .:. :.. ..: :: :: XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS 30 40 50 60 70 50 60 70 80 90 100 pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF : .:. .:.:.:. ...:: :: . :. . .. : . ..:.. :. : XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES 80 90 100 110 120 130 110 120 130 140 150 160 pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT ::.. : : ..:. . :::. : :: :. .: : .: XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT 140 150 160 170 180 190 170 180 190 200 210 220 pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL .. .: . .: : ::::.. ::.. :: .:.:..::: :::.:: XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS 200 210 220 230 240 250 230 240 250 260 270 280 pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE 260 270 280 290 300 310 >>XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr (409 aa) initn: 339 init1: 184 opt: 380 Z-score: 351.2 bits: 73.4 E(85289): 8e-13 Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:51-243) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL : : .:. :.. ..: :: :: XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS 30 40 50 60 70 50 60 70 80 90 100 pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF : .:. .:.:.:. ...:: :: . :. . .. : . ..:.. :. : XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES 80 90 100 110 120 130 110 120 130 140 150 160 pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT ::.. : : ..:. . :::. : :: :. .: : .: XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT 140 150 160 170 180 190 170 180 190 200 210 220 pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL .. .: . .: : ::::.. ::.. :: .:.:..::: :::.:: XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS 200 210 220 230 240 250 230 240 250 260 270 280 pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE 260 270 280 290 300 310 >>XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr (421 aa) initn: 339 init1: 184 opt: 380 Z-score: 351.1 bits: 73.5 E(85289): 8.1e-13 Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:63-255) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL : : .:. :.. ..: :: :: XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS 40 50 60 70 80 90 50 60 70 80 90 100 pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF : .:. .:.:.:. ...:: :: . :. . .. : . ..:.. :. : XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES 100 110 120 130 140 110 120 130 140 150 160 pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT ::.. : : ..:. . :::. : :: :. .: : .: XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT 150 160 170 180 190 200 170 180 190 200 210 220 pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL .. .: . .: : ::::.. ::.. :: .:.:..::: :::.:: XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS 210 220 230 240 250 260 230 240 250 260 270 280 pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE 270 280 290 300 310 320 >>XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr (421 aa) initn: 339 init1: 184 opt: 380 Z-score: 351.1 bits: 73.5 E(85289): 8.1e-13 Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:63-255) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL : : .:. :.. ..: :: :: XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS 40 50 60 70 80 90 50 60 70 80 90 100 pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF : .:. .:.:.:. ...:: :: . :. . .. : . ..:.. :. : XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES 100 110 120 130 140 110 120 130 140 150 160 pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT ::.. : : ..:. . :::. : :: :. .: : .: XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT 150 160 170 180 190 200 170 180 190 200 210 220 pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL .. .: . .: : ::::.. ::.. :: .:.:..::: :::.:: XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS 210 220 230 240 250 260 230 240 250 260 270 280 pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE 270 280 290 300 310 320 >>XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquitin-pr (421 aa) initn: 339 init1: 184 opt: 380 Z-score: 351.1 bits: 73.5 E(85289): 8.1e-13 Smith-Waterman score: 380; 29.2% identity (54.0% similar) in 202 aa overlap (16-215:63-255) 10 20 30 40 pF1KSD MTTARYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL : : .:. :.. ..: :: :: XP_016 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS 40 50 60 70 80 90 50 60 70 80 90 100 pF1KSD CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAE-IMQRYKKLQFEREVLF : .:. .:.:.:. ...:: :: . :. . .. : . ..:.. :. : XP_016 CWEQHCSVLVKDGVGVGVSCMAQDCPLR--TPEDFVFPLLPNEELREKYRRYLFRDYVES 100 110 120 130 140 110 120 130 140 150 160 pF1KSD DPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-IT ::.. : : ..:. . :::. : :: :. .: : .: XP_016 HYQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLT 150 160 170 180 190 200 170 180 190 200 210 220 pF1KSD FLPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFL .. .: . .: : ::::.. ::.. :: .:.:..::: :::.:: XP_016 KCADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGS 210 220 230 240 250 260 230 240 250 260 270 280 pF1KSD LIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCS XP_016 EYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQE 270 280 290 300 310 320 292 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:21:24 2016 done: Thu Nov 3 00:21:25 2016 Total Scan time: 6.030 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]