FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0170, 2089 aa 1>>>pF1KSDA0170 2089 - 2089 aa - 2089 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.5018+/-0.00139; mu= -23.2724+/- 0.083 mean_var=544.7762+/-113.958, 0's: 0 Z-trim(112.4): 117 B-trim: 0 in 0/52 Lambda= 0.054950 statistics sampled from 13042 (13141) to 13042 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.404), width: 16 Scan time: 6.250 The best scores are: opt bits E(32554) CCDS34384.1 MDC1 gene_id:9656|Hs108|chr6 (2089) 13800 1110.7 0 >>CCDS34384.1 MDC1 gene_id:9656|Hs108|chr6 (2089 aa) initn: 13800 init1: 13800 opt: 13800 Z-score: 5928.8 bits: 1110.7 E(32554): 0 Smith-Waterman score: 13800; 99.8% identity (100.0% similar) in 2089 aa overlap (1-2089:1-2089) 10 20 30 40 50 60 pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: CCDS34 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: CCDS34 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT ::::::::::::::::::::::::::::::::::::::: ::::.::::::::::::::: CCDS34 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST 2050 2060 2070 2080 2089 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:24:54 2016 done: Thu Nov 3 00:24:55 2016 Total Scan time: 6.250 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]