Result of FASTA (omim) for
pF1KSDA0170
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0170, 2089 aa
1>>>pF1KSDA0170 2089 - 2089 aa - 2089 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.8098+/-0.000574; mu= -25.0616+/- 0.035
mean_var=678.0279+/-147.029, 0's: 0 Z-trim(120.6): 309 B-trim: 1648 in 1/57
Lambda= 0.049255
statistics sampled from 35717 (36043) to 35717 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.423), width: 16
Scan time: 20.870
The best scores are: opt bits E(85289)
XP_016867008 (OMIM: 607593) PREDICTED: mediator of (2089) 13800 998.0 0
NP_055456 (OMIM: 607593) mediator of DNA damage ch (2089) 13800 998.0 0
XP_011513305 (OMIM: 607593) PREDICTED: mediator of (2089) 13800 998.0 0
XP_011513303 (OMIM: 607593) PREDICTED: mediator of (2089) 13800 998.0 0
XP_005249551 (OMIM: 607593) PREDICTED: mediator of (2089) 13800 998.0 0
XP_005249549 (OMIM: 607593) PREDICTED: mediator of (2110) 13800 998.0 0
XP_016867009 (OMIM: 607593) PREDICTED: mediator of (2088) 13783 996.7 0
XP_005249550 (OMIM: 607593) PREDICTED: mediator of (2109) 13783 996.7 0
XP_011513306 (OMIM: 607593) PREDICTED: mediator of (1961) 12911 934.8 0
XP_016867010 (OMIM: 607593) PREDICTED: mediator of (1899) 7302 536.2 1.3e-150
XP_005249554 (OMIM: 607593) PREDICTED: mediator of (1920) 7302 536.2 1.3e-150
XP_016867011 (OMIM: 607593) PREDICTED: mediator of (1845) 7135 524.3 4.9e-147
XP_005249555 (OMIM: 607593) PREDICTED: mediator of (1846) 7129 523.9 6.5e-147
NP_001290161 (OMIM: 208250,604283) proteoglycan 4 (1361) 667 64.6 8.8e-09
NP_001121180 (OMIM: 208250,604283) proteoglycan 4 (1363) 661 64.2 1.2e-08
NP_005798 (OMIM: 208250,604283) proteoglycan 4 iso (1404) 661 64.2 1.2e-08
NP_002448 (OMIM: 158370) mucin-2 precursor [Homo s (5289) 678 65.8 1.5e-08
XP_016855492 (OMIM: 208250,604283) PREDICTED: prot (1270) 633 62.1 4.4e-08
NP_001121182 (OMIM: 208250,604283) proteoglycan 4 (1270) 633 62.1 4.4e-08
NP_001121181 (OMIM: 208250,604283) proteoglycan 4 (1311) 633 62.2 4.5e-08
XP_016855491 (OMIM: 208250,604283) PREDICTED: prot (1311) 633 62.2 4.5e-08
XP_011510961 (OMIM: 606279) PREDICTED: target of N (1682) 596 59.6 3.4e-07
XP_005247351 (OMIM: 606279) PREDICTED: target of N (1754) 592 59.3 4.3e-07
XP_016861594 (OMIM: 606279) PREDICTED: target of N (1774) 578 58.3 8.6e-07
XP_011510953 (OMIM: 606279) PREDICTED: target of N (1726) 575 58.1 9.8e-07
XP_011510947 (OMIM: 606279) PREDICTED: target of N (1765) 572 57.9 1.2e-06
XP_005247359 (OMIM: 606279) PREDICTED: target of N (1725) 568 57.6 1.4e-06
XP_005247341 (OMIM: 606279) PREDICTED: target of N (1774) 568 57.6 1.4e-06
XP_011510941 (OMIM: 606279) PREDICTED: target of N (1773) 560 57.1 2.1e-06
XP_005247360 (OMIM: 606279) PREDICTED: target of N (1706) 558 56.9 2.2e-06
XP_016861595 (OMIM: 606279) PREDICTED: target of N (1768) 558 56.9 2.3e-06
XP_011510954 (OMIM: 606279) PREDICTED: target of N (1722) 553 56.6 2.9e-06
XP_005247342 (OMIM: 606279) PREDICTED: target of N (1773) 550 56.4 3.4e-06
XP_005247344 (OMIM: 606279) PREDICTED: target of N (1771) 549 56.3 3.6e-06
XP_016860310 (OMIM: 188840,600334,603689,604145,60 (34087) 595 60.5 3.7e-06
XP_016860309 (OMIM: 188840,600334,603689,604145,60 (34088) 595 60.5 3.7e-06
XP_011510950 (OMIM: 606279) PREDICTED: target of N (1747) 547 56.1 3.9e-06
XP_011510942 (OMIM: 606279) PREDICTED: target of N (1771) 546 56.1 4.2e-06
XP_006713635 (OMIM: 606279) PREDICTED: target of N (1719) 544 55.9 4.5e-06
XP_005247353 (OMIM: 606279) PREDICTED: target of N (1746) 543 55.9 4.8e-06
XP_006713634 (OMIM: 606279) PREDICTED: target of N (1721) 542 55.8 5e-06
XP_011510958 (OMIM: 606279) PREDICTED: target of N (1694) 540 55.6 5.4e-06
XP_016861596 (OMIM: 606279) PREDICTED: target of N (1724) 539 55.6 5.8e-06
XP_005247366 (OMIM: 606279) PREDICTED: target of N (1495) 536 55.3 6e-06
XP_005247358 (OMIM: 606279) PREDICTED: target of N (1726) 536 55.4 6.7e-06
XP_006713632 (OMIM: 606279) PREDICTED: target of N (1742) 536 55.4 6.7e-06
XP_005247356 (OMIM: 606279) PREDICTED: target of N (1744) 536 55.4 6.7e-06
XP_005247350 (OMIM: 606279) PREDICTED: target of N (1757) 536 55.4 6.8e-06
XP_005247348 (OMIM: 606279) PREDICTED: target of N (1767) 536 55.4 6.8e-06
XP_011510943 (OMIM: 606279) PREDICTED: target of N (1768) 536 55.4 6.8e-06
>>XP_016867008 (OMIM: 607593) PREDICTED: mediator of DNA (2089 aa)
initn: 13800 init1: 13800 opt: 13800 Z-score: 5319.7 bits: 998.0 E(85289): 0
Smith-Waterman score: 13800; 99.8% identity (100.0% similar) in 2089 aa overlap (1-2089:1-2089)
10 20 30 40 50 60
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT
::::::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::
XP_016 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080
pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
2050 2060 2070 2080
>>NP_055456 (OMIM: 607593) mediator of DNA damage checkp (2089 aa)
initn: 13800 init1: 13800 opt: 13800 Z-score: 5319.7 bits: 998.0 E(85289): 0
Smith-Waterman score: 13800; 99.8% identity (100.0% similar) in 2089 aa overlap (1-2089:1-2089)
10 20 30 40 50 60
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
NP_055 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
NP_055 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT
::::::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::
NP_055 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080
pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
2050 2060 2070 2080
>>XP_011513305 (OMIM: 607593) PREDICTED: mediator of DNA (2089 aa)
initn: 13800 init1: 13800 opt: 13800 Z-score: 5319.7 bits: 998.0 E(85289): 0
Smith-Waterman score: 13800; 99.8% identity (100.0% similar) in 2089 aa overlap (1-2089:1-2089)
10 20 30 40 50 60
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_011 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT
::::::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::
XP_011 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080
pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
2050 2060 2070 2080
>>XP_011513303 (OMIM: 607593) PREDICTED: mediator of DNA (2089 aa)
initn: 13800 init1: 13800 opt: 13800 Z-score: 5319.7 bits: 998.0 E(85289): 0
Smith-Waterman score: 13800; 99.8% identity (100.0% similar) in 2089 aa overlap (1-2089:1-2089)
10 20 30 40 50 60
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_011 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_011 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT
::::::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::
XP_011 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080
pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
2050 2060 2070 2080
>>XP_005249551 (OMIM: 607593) PREDICTED: mediator of DNA (2089 aa)
initn: 13800 init1: 13800 opt: 13800 Z-score: 5319.7 bits: 998.0 E(85289): 0
Smith-Waterman score: 13800; 99.8% identity (100.0% similar) in 2089 aa overlap (1-2089:1-2089)
10 20 30 40 50 60
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_005 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT
::::::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::
XP_005 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080
pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
2050 2060 2070 2080
>>XP_005249549 (OMIM: 607593) PREDICTED: mediator of DNA (2110 aa)
initn: 13800 init1: 13800 opt: 13800 Z-score: 5319.6 bits: 998.0 E(85289): 0
Smith-Waterman score: 13800; 99.8% identity (100.0% similar) in 2089 aa overlap (1-2089:22-2110)
10 20 30
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSG
:::::::::::::::::::::::::::::::::::::::
XP_005 MGHPTFPTCQQFPSRVAYFQIMEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD AHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD ILRPPKVLSPGVSHRLRDQELILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILRPPKVLSPGVSHRLRDQELILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD QRLLLAEDSEEEVDFLSERRMVKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRLLLAEDSEEEVDFLSERRMVKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD TDVEEGQQPATEEASSAARRGATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDVEEGQQPATEEASSAARRGATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD NGVVPAGVILERSQPPGEDSDTDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGVVPAGVILERSQPPGEDSDTDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD ATPVVIPMKKRKIFHGVGTRGPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATPVVIPMKKRKIFHGVGTRGPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD INSDTDDEEEVSAALTLAHLKESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INSDTDDEEEVSAALTLAHLKESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEE
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD EELPVENREAVLKDHTKIRALVRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EELPVENREAVLKDHTKIRALVRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD DINTQVEKEVPPGSAIMHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCET
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_005 DINTQVEKEVPPGSAIIHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCET
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD DAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLP
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD ISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQAT
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD QCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRE
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD SEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKE
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD TAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGE
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD SASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPK
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD VILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSP
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD RRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQK
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_005 RRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQK
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KSD HLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KSD ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVT
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KSD SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KSD PEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDR
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KSD PVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KSD VKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTS
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KSD TDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTD
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KSD RSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQP
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KSD PTSTDRPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRC
::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRC
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KSD RTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASD
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KSD LEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPS
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KSD CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLL
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KSD ETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVII
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KSD KEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTG
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940 1950
pF1KSD VVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA
1930 1940 1950 1960 1970 1980
1960 1970 1980 1990 2000 2010
pF1KSD GFFLPPDEYVVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFFLPPDEYVVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIIS
1990 2000 2010 2020 2030 2040
2020 2030 2040 2050 2060 2070
pF1KSD CCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAF
2050 2060 2070 2080 2090 2100
2080
pF1KSD VLSPLEMSST
::::::::::
XP_005 VLSPLEMSST
2110
>>XP_016867009 (OMIM: 607593) PREDICTED: mediator of DNA (2088 aa)
initn: 9126 init1: 9126 opt: 13783 Z-score: 5313.1 bits: 996.7 E(85289): 0
Smith-Waterman score: 13783; 99.8% identity (99.9% similar) in 2089 aa overlap (1-2089:1-2088)
10 20 30 40 50 60
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLE-VQSMEDEPTQ
670 680 690 700 710
730 740 750 760 770 780
pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
720 730 740 750 760 770
790 800 810 820 830 840
pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
780 790 800 810 820 830
850 860 870 880 890 900
pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
840 850 860 870 880 890
910 920 930 940 950 960
pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT
::::::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::
XP_016 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
1920 1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
1980 1990 2000 2010 2020 2030
2050 2060 2070 2080
pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
2040 2050 2060 2070 2080
>>XP_005249550 (OMIM: 607593) PREDICTED: mediator of DNA (2109 aa)
initn: 9126 init1: 9126 opt: 13783 Z-score: 5313.1 bits: 996.7 E(85289): 0
Smith-Waterman score: 13783; 99.8% identity (99.9% similar) in 2089 aa overlap (1-2089:22-2109)
10 20 30
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSG
:::::::::::::::::::::::::::::::::::::::
XP_005 MGHPTFPTCQQFPSRVAYFQIMEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSG
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD AHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD ILRPPKVLSPGVSHRLRDQELILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILRPPKVLSPGVSHRLRDQELILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD QRLLLAEDSEEEVDFLSERRMVKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRLLLAEDSEEEVDFLSERRMVKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD TDVEEGQQPATEEASSAARRGATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDVEEGQQPATEEASSAARRGATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD NGVVPAGVILERSQPPGEDSDTDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGVVPAGVILERSQPPGEDSDTDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD ATPVVIPMKKRKIFHGVGTRGPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATPVVIPMKKRKIFHGVGTRGPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD INSDTDDEEEVSAALTLAHLKESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INSDTDDEEEVSAALTLAHLKESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEE
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD EELPVENREAVLKDHTKIRALVRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EELPVENREAVLKDHTKIRALVRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD DINTQVEKEVPPGSAIMHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCET
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_005 DINTQVEKEVPPGSAIIHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCET
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD DAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLP
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD ISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQAT
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD QCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRE
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QCFLENQGLE-VQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRE
730 740 750 760 770
760 770 780 790 800 810
pF1KSD SEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKE
780 790 800 810 820 830
820 830 840 850 860 870
pF1KSD TAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGE
840 850 860 870 880 890
880 890 900 910 920 930
pF1KSD SASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPK
900 910 920 930 940 950
940 950 960 970 980 990
pF1KSD VILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSP
960 970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KSD RRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQK
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_005 RRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQK
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KSD HLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP
1080 1090 1100 1110 1120 1130
1120 1130 1140 1150 1160 1170
pF1KSD ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVT
1140 1150 1160 1170 1180 1190
1180 1190 1200 1210 1220 1230
pF1KSD SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT
1200 1210 1220 1230 1240 1250
1240 1250 1260 1270 1280 1290
pF1KSD PEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDR
1260 1270 1280 1290 1300 1310
1300 1310 1320 1330 1340 1350
pF1KSD PVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS
1320 1330 1340 1350 1360 1370
1360 1370 1380 1390 1400 1410
pF1KSD VKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTS
1380 1390 1400 1410 1420 1430
1420 1430 1440 1450 1460 1470
pF1KSD TDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTD
1440 1450 1460 1470 1480 1490
1480 1490 1500 1510 1520 1530
pF1KSD RSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQP
1500 1510 1520 1530 1540 1550
1540 1550 1560 1570 1580 1590
pF1KSD PTSTDRPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRC
::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRC
1560 1570 1580 1590 1600 1610
1600 1610 1620 1630 1640 1650
pF1KSD RTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASD
1620 1630 1640 1650 1660 1670
1660 1670 1680 1690 1700 1710
pF1KSD LEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPS
1680 1690 1700 1710 1720 1730
1720 1730 1740 1750 1760 1770
pF1KSD CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLL
1740 1750 1760 1770 1780 1790
1780 1790 1800 1810 1820 1830
pF1KSD ETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVII
1800 1810 1820 1830 1840 1850
1840 1850 1860 1870 1880 1890
pF1KSD KEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTG
1860 1870 1880 1890 1900 1910
1900 1910 1920 1930 1940 1950
pF1KSD VVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA
1920 1930 1940 1950 1960 1970
1960 1970 1980 1990 2000 2010
pF1KSD GFFLPPDEYVVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFFLPPDEYVVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIIS
1980 1990 2000 2010 2020 2030
2020 2030 2040 2050 2060 2070
pF1KSD CCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAF
2040 2050 2060 2070 2080 2090
2080
pF1KSD VLSPLEMSST
::::::::::
XP_005 VLSPLEMSST
2100
>>XP_011513306 (OMIM: 607593) PREDICTED: mediator of DNA (1961 aa)
initn: 12911 init1: 12911 opt: 12911 Z-score: 4978.6 bits: 934.8 E(85289): 0
Smith-Waterman score: 12911; 99.8% identity (99.9% similar) in 1960 aa overlap (130-2089:2-1961)
100 110 120 130 140 150
pF1KSD ILRPPKVLSPGVSHRLRDQELILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQP
::::::::::::::::::::::::::::::
XP_011 MYHRLDVSLPFVSRGPLTVEETPRVQGETQP
10 20 30
160 170 180 190 200 210
pF1KSD QRLLLAEDSEEEVDFLSERRMVKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRLLLAEDSEEEVDFLSERRMVKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSD
40 50 60 70 80 90
220 230 240 250 260 270
pF1KSD TDVEEGQQPATEEASSAARRGATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVEEGQQPATEEASSAARRGATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAG
100 110 120 130 140 150
280 290 300 310 320 330
pF1KSD NGVVPAGVILERSQPPGEDSDTDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGVVPAGVILERSQPPGEDSDTDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIP
160 170 180 190 200 210
340 350 360 370 380 390
pF1KSD ATPVVIPMKKRKIFHGVGTRGPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATPVVIPMKKRKIFHGVGTRGPGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMV
220 230 240 250 260 270
400 410 420 430 440 450
pF1KSD INSDTDDEEEVSAALTLAHLKESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INSDTDDEEEVSAALTLAHLKESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEE
280 290 300 310 320 330
460 470 480 490 500 510
pF1KSD EELPVENREAVLKDHTKIRALVRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELPVENREAVLKDHTKIRALVRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTV
340 350 360 370 380 390
520 530 540 550 560 570
pF1KSD DINTQVEKEVPPGSAIMHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCET
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_011 DINTQVEKEVPPGSAIIHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCET
400 410 420 430 440 450
580 590 600 610 620 630
pF1KSD DAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAEEGTSLTASVVADVRKSQLPAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLP
460 470 480 490 500 510
640 650 660 670 680 690
pF1KSD ISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQAT
520 530 540 550 560 570
700 710 720 730 740 750
pF1KSD QCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRE
580 590 600 610 620 630
760 770 780 790 800 810
pF1KSD SEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKE
640 650 660 670 680 690
820 830 840 850 860 870
pF1KSD TAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGE
700 710 720 730 740 750
880 890 900 910 920 930
pF1KSD SASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPK
760 770 780 790 800 810
940 950 960 970 980 990
pF1KSD VILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSP
820 830 840 850 860 870
1000 1010 1020 1030 1040 1050
pF1KSD RRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQK
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 RRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQK
880 890 900 910 920 930
1060 1070 1080 1090 1100 1110
pF1KSD HLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP
940 950 960 970 980 990
1120 1130 1140 1150 1160 1170
pF1KSD ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVT
1000 1010 1020 1030 1040 1050
1180 1190 1200 1210 1220 1230
pF1KSD SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKT
1060 1070 1080 1090 1100 1110
1240 1250 1260 1270 1280 1290
pF1KSD PEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDR
1120 1130 1140 1150 1160 1170
1300 1310 1320 1330 1340 1350
pF1KSD PVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS
1180 1190 1200 1210 1220 1230
1360 1370 1380 1390 1400 1410
pF1KSD VKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTS
1240 1250 1260 1270 1280 1290
1420 1430 1440 1450 1460 1470
pF1KSD TDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTD
1300 1310 1320 1330 1340 1350
1480 1490 1500 1510 1520 1530
pF1KSD RSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQP
1360 1370 1380 1390 1400 1410
1540 1550 1560 1570 1580 1590
pF1KSD PTSTDRPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRC
::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRC
1420 1430 1440 1450 1460 1470
1600 1610 1620 1630 1640 1650
pF1KSD RTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASD
1480 1490 1500 1510 1520 1530
1660 1670 1680 1690 1700 1710
pF1KSD LEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPS
1540 1550 1560 1570 1580 1590
1720 1730 1740 1750 1760 1770
pF1KSD CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLL
1600 1610 1620 1630 1640 1650
1780 1790 1800 1810 1820 1830
pF1KSD ETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVII
1660 1670 1680 1690 1700 1710
1840 1850 1860 1870 1880 1890
pF1KSD KEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTG
1720 1730 1740 1750 1760 1770
1900 1910 1920 1930 1940 1950
pF1KSD VVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA
1780 1790 1800 1810 1820 1830
1960 1970 1980 1990 2000 2010
pF1KSD GFFLPPDEYVVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFFLPPDEYVVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIIS
1840 1850 1860 1870 1880 1890
2020 2030 2040 2050 2060 2070
pF1KSD CCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAF
1900 1910 1920 1930 1940 1950
2080
pF1KSD VLSPLEMSST
::::::::::
XP_011 VLSPLEMSST
1960
>>XP_016867010 (OMIM: 607593) PREDICTED: mediator of DNA (1899 aa)
initn: 8042 init1: 7125 opt: 7302 Z-score: 2824.8 bits: 536.2 E(85289): 1.3e-150
Smith-Waterman score: 12153; 90.7% identity (90.9% similar) in 2089 aa overlap (1-2089:1-1899)
10 20 30 40 50 60
pF1KSD MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDTQAIDWDVEEEEETEQSSESLRCNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILFADLLCQYHRLDVSLPFVSRGPLTVEETPRVQGETQPQRLLLAEDSEEEVDFLSERRM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKSRTTSSSVIVPESDEEGHSPVLGGLGPPFAFNLNSDTDVEEGQQPATEEASSAARRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATVEAKQSEAEVVTEIQLEKDQPLVKERDNDTKVKRGAGNGVVPAGVILERSQPPGEDSD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVDDDSRPPGRPAEVHLERAQPFGFIDSDTDAEEERIPATPVVIPMKKRKIFHGVGTRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAPGLAHLQESQAGSDTDVEEGKAPQAVPLEKSQASMVINSDTDDEEEVSAALTLAHLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESQPAIWNRDAEEDMPQRVVLLQRSQTTTERDSDTDVEEEELPVENREAVLKDHTKIRAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIMHIKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 VRAHSEKDQPPFGDSDDSVEADKSSPGIHLERSQASTTVDINTQVEKEVPPGSAIIHIKK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETDAEEGTSLTASVVADVRKSQL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAEGDAGAEWAAAVLKQERAHEVGAQGGPPVAQVEQDLPISRENLTDLVVDTDTLGESTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQREGAQVPTGREREQHVGGTKDSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMLTPPQELGPSHCSFQTTGTLDEPWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMGIPKETAERVGPERGPLERETEKLLP
:::::::::::::::::::::::::::::::::::
XP_016 PPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKVMG-------------------------
790 800 810
850 860 870 880 890 900
pF1KSD ERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEI
XP_016 ------------------------------------------------------------
910 920 930 940 950 960
pF1KSD QEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG
XP_016 ------------------------------------------------------------
970 980 990 1000 1010 1020
pF1KSD QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI
:::::::::::::::
XP_016 ---------------------------------------------LLNCKMPPAEKASRI
820 830
1030 1040 1050 1060 1070 1080
pF1KSD RAAEKVSRGDQESPDACLPPAVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::
XP_016 RAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRK
840 850 860 870 880 890
1090 1100 1110 1120 1130 1140
pF1KSD TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPK
900 910 920 930 940 950
1150 1160 1170 1180 1190 1200
pF1KSD PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPE
960 970 980 990 1000 1010
1210 1220 1230 1240 1250 1260
pF1KSD TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPV
1020 1030 1040 1050 1060 1070
1270 1280 1290 1300 1310 1320
pF1KSD TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVK
1080 1090 1100 1110 1120 1130
1330 1340 1350 1360 1370 1380
pF1KSD TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE
1140 1150 1160 1170 1180 1190
1390 1400 1410 1420 1430 1440
pF1KSD QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRS
1200 1210 1220 1230 1240 1250
1450 1460 1470 1480 1490 1500
pF1KSD SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA
1260 1270 1280 1290 1300 1310
1510 1520 1530 1540 1550 1560
pF1KSD STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPPTSTDRPVTPEPTSRATRGRT
::::::::::::::::::::::::::::::::::::::: ::::.:::::::::::::::
XP_016 STDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRT
1320 1330 1340 1350 1360 1370
1570 1580 1590 1600 1610 1620
pF1KSD NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPH
1380 1390 1400 1410 1420 1430
1630 1640 1650 1660 1670 1680
pF1KSD PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQ
1440 1450 1460 1470 1480 1490
1690 1700 1710 1720 1730 1740
pF1KSD SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHK
1500 1510 1520 1530 1540 1550
1750 1760 1770 1780 1790 1800
pF1KSD PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFT
1560 1570 1580 1590 1600 1610
1810 1820 1830 1840 1850 1860
pF1KSD PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPK
1620 1630 1640 1650 1660 1670
1870 1880 1890 1900 1910 1920
pF1KSD PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALGGSLAGSA
1680 1690 1700 1710 1720 1730
1930 1940 1950 1960 1970 1980
pF1KSD AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFG
1740 1750 1760 1770 1780 1790
1990 2000 2010 2020 2030 2040
pF1KSD FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
1800 1810 1820 1830 1840 1850
2050 2060 2070 2080
pF1KSD TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSPLEMSST
1860 1870 1880 1890
2089 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:24:55 2016 done: Thu Nov 3 00:24:58 2016
Total Scan time: 20.870 Total Display time: 1.530
Function used was FASTA [36.3.4 Apr, 2011]