FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0172, 1352 aa 1>>>pF1KSDA0172 1352 - 1352 aa - 1352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2411+/-0.000524; mu= 0.1800+/- 0.033 mean_var=328.8739+/-67.925, 0's: 0 Z-trim(118.3): 319 B-trim: 1049 in 1/56 Lambda= 0.070723 statistics sampled from 30671 (31111) to 30671 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.365), width: 16 Scan time: 13.130 The best scores are: opt bits E(85289) NP_055973 (OMIM: 607704,612900) KN motif and ankyr (1352) 8808 914.2 0 XP_016870003 (OMIM: 607704,612900) PREDICTED: KN m (1352) 8808 914.2 0 NP_001243805 (OMIM: 607704,612900) KN motif and an (1352) 8808 914.2 0 NP_001243806 (OMIM: 607704,612900) KN motif and an (1352) 8808 914.2 0 XP_016870004 (OMIM: 607704,612900) PREDICTED: KN m (1352) 8808 914.2 0 XP_005251468 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_016870000 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_011516121 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_016870002 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_011516123 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_011516122 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_006716806 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_016870001 (OMIM: 607704,612900) PREDICTED: KN m (1364) 8663 899.4 0 XP_016870019 (OMIM: 607704,612900) PREDICTED: KN m (1194) 7733 804.5 0 XP_016870017 (OMIM: 607704,612900) PREDICTED: KN m (1194) 7733 804.5 0 XP_016870016 (OMIM: 607704,612900) PREDICTED: KN m (1194) 7733 804.5 0 NP_694856 (OMIM: 607704,612900) KN motif and ankyr (1194) 7733 804.5 0 XP_016870018 (OMIM: 607704,612900) PREDICTED: KN m (1194) 7733 804.5 0 XP_005251474 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_005251471 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_005251473 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_016870022 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_005251472 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_005251476 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_016870015 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_005251475 (OMIM: 607704,612900) PREDICTED: KN m (1206) 7588 789.7 0 XP_016870010 (OMIM: 607704,612900) PREDICTED: KN m (1272) 6528 681.6 9.8e-195 XP_016870011 (OMIM: 607704,612900) PREDICTED: KN m (1272) 6528 681.6 9.8e-195 XP_016870012 (OMIM: 607704,612900) PREDICTED: KN m (1272) 6528 681.6 9.8e-195 XP_016870009 (OMIM: 607704,612900) PREDICTED: KN m (1284) 6528 681.6 9.9e-195 XP_016870008 (OMIM: 607704,612900) PREDICTED: KN m (1284) 6528 681.6 9.9e-195 XP_016870014 (OMIM: 607704,612900) PREDICTED: KN m (1254) 6158 643.8 2.2e-183 XP_016870013 (OMIM: 607704,612900) PREDICTED: KN m (1266) 6158 643.8 2.3e-183 XP_016870006 (OMIM: 607704,612900) PREDICTED: KN m (1334) 6158 643.8 2.4e-183 XP_016870007 (OMIM: 607704,612900) PREDICTED: KN m (1334) 6158 643.8 2.4e-183 XP_016870005 (OMIM: 607704,612900) PREDICTED: KN m (1346) 6158 643.8 2.4e-183 XP_016870030 (OMIM: 607704,612900) PREDICTED: KN m (1114) 5453 571.8 9.3e-162 XP_016870028 (OMIM: 607704,612900) PREDICTED: KN m (1114) 5453 571.8 9.3e-162 XP_016870029 (OMIM: 607704,612900) PREDICTED: KN m (1114) 5453 571.8 9.3e-162 XP_016870026 (OMIM: 607704,612900) PREDICTED: KN m (1126) 5453 571.8 9.4e-162 XP_016870027 (OMIM: 607704,612900) PREDICTED: KN m (1126) 5453 571.8 9.4e-162 XP_016870031 (OMIM: 607704,612900) PREDICTED: KN m (1096) 5083 534.1 2.1e-150 XP_016870025 (OMIM: 607704,612900) PREDICTED: KN m (1176) 5083 534.1 2.2e-150 XP_016870023 (OMIM: 607704,612900) PREDICTED: KN m (1176) 5083 534.1 2.2e-150 XP_016870024 (OMIM: 607704,612900) PREDICTED: KN m (1176) 5083 534.1 2.2e-150 XP_016870020 (OMIM: 607704,612900) PREDICTED: KN m (1188) 5083 534.1 2.3e-150 XP_016870021 (OMIM: 607704,612900) PREDICTED: KN m (1188) 5083 534.1 2.3e-150 NP_001316380 (OMIM: 614610,616099) KN motif and an ( 851) 1100 127.6 3.8e-28 NP_001129663 (OMIM: 614610,616099) KN motif and an ( 851) 1100 127.6 3.8e-28 NP_056308 (OMIM: 614610,616099) KN motif and ankyr ( 859) 1065 124.0 4.6e-27 >>NP_055973 (OMIM: 607704,612900) KN motif and ankyrin r (1352 aa) initn: 8808 init1: 8808 opt: 8808 Z-score: 4874.0 bits: 914.2 E(85289): 0 Smith-Waterman score: 8808; 99.9% identity (100.0% similar) in 1352 aa overlap (1-1352:1-1352) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: NP_055 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::::::::::::::::::::::: NP_055 YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD 1330 1340 1350 >>XP_016870003 (OMIM: 607704,612900) PREDICTED: KN motif (1352 aa) initn: 8808 init1: 8808 opt: 8808 Z-score: 4874.0 bits: 914.2 E(85289): 0 Smith-Waterman score: 8808; 99.9% identity (100.0% similar) in 1352 aa overlap (1-1352:1-1352) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::::::::::::::::::::::: XP_016 YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD 1330 1340 1350 >>NP_001243805 (OMIM: 607704,612900) KN motif and ankyri (1352 aa) initn: 8808 init1: 8808 opt: 8808 Z-score: 4874.0 bits: 914.2 E(85289): 0 Smith-Waterman score: 8808; 99.9% identity (100.0% similar) in 1352 aa overlap (1-1352:1-1352) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: NP_001 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::::::::::::::::::::::: NP_001 YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD 1330 1340 1350 >>NP_001243806 (OMIM: 607704,612900) KN motif and ankyri (1352 aa) initn: 8808 init1: 8808 opt: 8808 Z-score: 4874.0 bits: 914.2 E(85289): 0 Smith-Waterman score: 8808; 99.9% identity (100.0% similar) in 1352 aa overlap (1-1352:1-1352) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: NP_001 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::::::::::::::::::::::: NP_001 YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD 1330 1340 1350 >>XP_016870004 (OMIM: 607704,612900) PREDICTED: KN motif (1352 aa) initn: 8808 init1: 8808 opt: 8808 Z-score: 4874.0 bits: 914.2 E(85289): 0 Smith-Waterman score: 8808; 99.9% identity (100.0% similar) in 1352 aa overlap (1-1352:1-1352) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::::::::::::::::::::::: XP_016 YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD 1330 1340 1350 >>XP_005251468 (OMIM: 607704,612900) PREDICTED: KN motif (1364 aa) initn: 8663 init1: 8663 opt: 8663 Z-score: 4794.0 bits: 899.4 E(85289): 0 Smith-Waterman score: 8663; 99.9% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_005 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::: XP_005 YAHVNFAKAQSPVSVVHLAFVNRLKSTRLVDPLPPGIDGRQILC 1330 1340 1350 1360 >>XP_016870000 (OMIM: 607704,612900) PREDICTED: KN motif (1364 aa) initn: 8663 init1: 8663 opt: 8663 Z-score: 4794.0 bits: 899.4 E(85289): 0 Smith-Waterman score: 8663; 99.9% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::: XP_016 YAHVNFAKAQSPVSVVHLAFVNRLKSTRLVDPLPPGIDGRQILC 1330 1340 1350 1360 >>XP_011516121 (OMIM: 607704,612900) PREDICTED: KN motif (1364 aa) initn: 8663 init1: 8663 opt: 8663 Z-score: 4794.0 bits: 899.4 E(85289): 0 Smith-Waterman score: 8663; 99.9% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_011 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::: XP_011 YAHVNFAKAQSPVSVVHLAFVNRLKSTRLVDPLPPGIDGRQILC 1330 1340 1350 1360 >>XP_016870002 (OMIM: 607704,612900) PREDICTED: KN motif (1364 aa) initn: 8663 init1: 8663 opt: 8663 Z-score: 4794.0 bits: 899.4 E(85289): 0 Smith-Waterman score: 8663; 99.9% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::: XP_016 YAHVNFAKAQSPVSVVHLAFVNRLKSTRLVDPLPPGIDGRQILC 1330 1340 1350 1360 >>XP_011516123 (OMIM: 607704,612900) PREDICTED: KN motif (1364 aa) initn: 8663 init1: 8663 opt: 8663 Z-score: 4794.0 bits: 899.4 E(85289): 0 Smith-Waterman score: 8663; 99.9% identity (100.0% similar) in 1332 aa overlap (1-1332:1-1332) 10 20 30 40 50 60 pF1KSD MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHTTKVNGSASGKAGDILSGDQDKEQKDPYFVETPYGYQLDLDFLKYVDDIQKGNTIKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNIQKRRKPSVPCPEPRTTSGQQGIWTSTESLSSSNSDDNKQCPNFLIARSQVTSTPISK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPLETSLPFLTIPENRQLPPPSPQLPKHNLHVTKTLMETRRRLEQERATMQMTPGEFR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPRLASFGGMGTTSSLPSFVGSGNHNPAKHQLQNGYQGNGDYGSYAPAAPTTSSMGSSIR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSPLSSGISTPVTNVSPMHLQHIREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVSQLKNQRAASQINVCGVRKRSYSAGNASQLEQLSRARRSGGELYIDYEEEEMETVEQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQRIKEFRQLTADMQALEQKIQDSSCEASSELRENGECRSVAVGAEENMNDIVVYHRGSR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIEALKEKIYRLEVQLRETT :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_011 SCKDAAVGTLVEMRNCGVSVTEAMLGVMTEADKEIELQQQTIESLKEKIYRLEVQLRETT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDREMTKLKQELQAAGSRKKVDKATMAQPLVFSKVVEAVVQTRDQMVGSHMDLVDTCVGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVETNSVGISCQPECKNKVVGPELPMNWWIVKERVEMHDRCAGRSVEMCDKSVSVEVSVC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETGSNTEESVNDLTLLKTNLNLKEVRSIGCGDCSVDVTVCSPKECASRGVNTEAVSQVEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMAVPRTADQDTSTDLEQVHQFTNTETATLIESCTNTCLSTLDKQTSTQTVETRTVAVG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGRVKDINSSTKTRSIGVGTLLSGHSGFDRPSAVKTKESGVGQININDNYLVGLKMRTIA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGPPQLTVGLTASRRSVGVGDDPVGESLENPQPQAPLGMMTGLDHYIERIQKLLAEQQTL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAENYSELAEAFGEPHSQMGSLNSQLISTLSSINSVMKSASTEELRNPDFQKTSLGKITG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NYLGYTCKCGGLQSGSPLSSQTSQPEQEVGTSEGKPISSLDAFPTQEGTLSPVNLTDDQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGLYACTNNESTLKSIMKKKDGNKDSNGAKKNLQFVGINGGYETTSSDDSSSDESSSSE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDDECDVIEYPLEEEEEEEDEDTRGMAEGHHAVNIEGLKSARVEDEMQVQECEPEKVEIR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERYELSEKMLSACNLLKNTINDPKALTSKDMRFCLNTLQHEWFRVSSQKSAIPAMVGDYI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQNKAGYTPI 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLAALAAVEAEKDMRIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLL 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD YAHVNFAKAQSPGTPRLGRKTSPGPTHRGSFD :::::::::::: XP_011 YAHVNFAKAQSPVSVVHLAFVNRLKSTRLVDPLPPGIDGRQILC 1330 1340 1350 1360 1352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:26:57 2016 done: Thu Nov 3 00:26:59 2016 Total Scan time: 13.130 Total Display time: 0.620 Function used was FASTA [36.3.4 Apr, 2011]