FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0174, 364 aa 1>>>pF1KSDA0174 364 - 364 aa - 364 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1782+/-0.000992; mu= 0.5002+/- 0.060 mean_var=258.0967+/-52.282, 0's: 0 Z-trim(113.5): 13 B-trim: 0 in 0/53 Lambda= 0.079833 statistics sampled from 14168 (14175) to 14168 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.435), width: 16 Scan time: 2.520 The best scores are: opt bits E(32554) CCDS59272.1 IST1 gene_id:9798|Hs108|chr16 ( 366) 2393 288.4 6.7e-78 CCDS59271.1 IST1 gene_id:9798|Hs108|chr16 ( 379) 2393 288.4 6.9e-78 CCDS10905.1 IST1 gene_id:9798|Hs108|chr16 ( 360) 1863 227.3 1.6e-59 CCDS59273.1 IST1 gene_id:9798|Hs108|chr16 ( 335) 1654 203.2 2.6e-52 CCDS59274.1 IST1 gene_id:9798|Hs108|chr16 ( 218) 1468 181.6 5.4e-46 >>CCDS59272.1 IST1 gene_id:9798|Hs108|chr16 (366 aa) initn: 1586 init1: 1550 opt: 2393 Z-score: 1512.0 bits: 288.4 E(32554): 6.7e-78 Smith-Waterman score: 2393; 99.5% identity (99.5% similar) in 366 aa overlap (1-364:1-366) 10 20 30 40 50 60 pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD 130 140 150 160 170 180 190 200 210 220 230 pF1KSD SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP--S ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : CCDS59 SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPMPS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE 310 320 330 340 350 360 360 pF1KSD ELKKKT :::::: CCDS59 ELKKKT >>CCDS59271.1 IST1 gene_id:9798|Hs108|chr16 (379 aa) initn: 1586 init1: 1550 opt: 2393 Z-score: 1511.8 bits: 288.4 E(32554): 6.9e-78 Smith-Waterman score: 2393; 99.5% identity (99.5% similar) in 366 aa overlap (1-364:14-379) 10 20 30 40 pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAG ::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MVFKLKTKEEQHSMLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAG 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD KDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 KDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD PRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD EIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGT 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD VPMPMPMPMP--SANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDD :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VPMPMPMPMPMPSANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDD 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD INADKNISSAQIVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 INADKNISSAQIVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSAS 310 320 330 340 350 360 350 360 pF1KSD EDIDFDDLSRRFEELKKKT ::::::::::::::::::: CCDS59 EDIDFDDLSRRFEELKKKT 370 >>CCDS10905.1 IST1 gene_id:9798|Hs108|chr16 (360 aa) initn: 1572 init1: 1550 opt: 1863 Z-score: 1182.2 bits: 227.3 E(32554): 1.6e-59 Smith-Waterman score: 1863; 92.6% identity (94.5% similar) in 310 aa overlap (1-307:1-310) 10 20 30 40 50 60 pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD 130 140 150 160 170 180 190 200 210 220 230 pF1KSD SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP--S ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : CCDS10 SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPMPS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV ::::::::::::::::::::::::::::::::::::::::::::. . .. .: CCDS10 ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESMTLMLIRISLLHRLLV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD -GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRF :. :: : CCDS10 LDPSQKPLQSFLPDLQITMTTLSYQSCHLCQTHYQLHLLVPAPQHLKTLTLMIFPGGLKS 310 320 330 340 350 360 >>CCDS59273.1 IST1 gene_id:9798|Hs108|chr16 (335 aa) initn: 1753 init1: 1545 opt: 1654 Z-score: 1052.5 bits: 203.2 E(32554): 2.6e-52 Smith-Waterman score: 2094; 91.0% identity (91.0% similar) in 366 aa overlap (1-364:1-335) 10 20 30 40 50 60 pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD 130 140 150 160 170 180 190 200 210 220 230 pF1KSD SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP--S ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : CCDS59 SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPMPS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV ::::::::::::: :::::::::::::::: CCDS59 ANTPFSYPLPKGP-------------------------------VDDINADKNISSAQIV 250 260 300 310 320 330 340 350 pF1KSD GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE 270 280 290 300 310 320 360 pF1KSD ELKKKT :::::: CCDS59 ELKKKT 330 >>CCDS59274.1 IST1 gene_id:9798|Hs108|chr16 (218 aa) initn: 941 init1: 941 opt: 1468 Z-score: 939.2 bits: 181.6 E(32554): 5.4e-46 Smith-Waterman score: 1468; 99.1% identity (99.1% similar) in 218 aa overlap (149-364:1-218) 120 130 140 150 160 170 pF1KSD IVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYE :::::::::::::::::::::::::::::: CCDS59 MHKLSVEAPPKILVERYLIEIAKNYNVPYE 10 20 30 180 190 200 210 220 230 pF1KSD PDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPM 40 50 60 70 80 90 240 250 260 270 280 290 pF1KSD -SANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PSANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQ 100 110 120 130 140 150 300 310 320 330 340 350 pF1KSD IVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 IVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRR 160 170 180 190 200 210 360 pF1KSD FEELKKKT :::::::: CCDS59 FEELKKKT 364 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:28:50 2016 done: Thu Nov 3 00:28:50 2016 Total Scan time: 2.520 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]