FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0181, 2063 aa 1>>>pF1KSDA0181 2063 - 2063 aa - 2063 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 18.9767+/-0.000545; mu= -40.2135+/- 0.034 mean_var=842.6535+/-181.086, 0's: 0 Z-trim(123.7): 319 B-trim: 1595 in 1/60 Lambda= 0.044182 statistics sampled from 43686 (44106) to 43686 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.517), width: 16 Scan time: 24.760 The best scores are: opt bits E(85289) NP_001305169 (OMIM: 605299) nuclear receptor coact (2063) 13985 908.6 0 NP_054790 (OMIM: 605299) nuclear receptor coactiva (2063) 13985 908.6 0 XP_011527023 (OMIM: 605299) PREDICTED: nuclear rec (2068) 13965 907.3 0 XP_006723818 (OMIM: 605299) PREDICTED: nuclear rec (1975) 13395 870.9 0 XP_011527028 (OMIM: 605299) PREDICTED: nuclear rec (2057) 11780 768.0 0 XP_011527029 (OMIM: 605299) PREDICTED: nuclear rec (2056) 11754 766.4 0 XP_016883233 (OMIM: 605299) PREDICTED: nuclear rec (2051) 10674 697.5 3.8e-199 XP_016883234 (OMIM: 605299) PREDICTED: nuclear rec (2039) 10612 693.6 5.9e-198 XP_016883228 (OMIM: 605299) PREDICTED: nuclear rec (2087) 10608 693.3 7.2e-198 XP_016883229 (OMIM: 605299) PREDICTED: nuclear rec (2087) 10608 693.3 7.2e-198 XP_016883231 (OMIM: 605299) PREDICTED: nuclear rec (2082) 10606 693.2 7.8e-198 XP_016883230 (OMIM: 605299) PREDICTED: nuclear rec (2086) 10591 692.2 1.5e-197 XP_016883236 (OMIM: 605299) PREDICTED: nuclear rec (1907) 10583 691.7 2e-197 XP_016883232 (OMIM: 605299) PREDICTED: nuclear rec (2058) 10223 668.8 1.7e-190 XP_016883235 (OMIM: 605299) PREDICTED: nuclear rec (1999) 10018 655.7 1.5e-186 XP_016883238 (OMIM: 605299) PREDICTED: nuclear rec (1650) 7463 492.8 1.3e-137 XP_016883237 (OMIM: 605299) PREDICTED: nuclear rec (1651) 7463 492.8 1.3e-137 NP_001229468 (OMIM: 605299) nuclear receptor coact (1070) 6800 450.4 4.8e-125 XP_016883240 (OMIM: 605299) PREDICTED: nuclear rec (1070) 6800 450.4 4.8e-125 XP_016883239 (OMIM: 605299) PREDICTED: nuclear rec (1094) 3423 235.2 3.1e-60 XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 665 59.5 4.4e-07 XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 665 59.5 4.4e-07 XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 665 59.5 4.4e-07 XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 665 59.5 4.4e-07 XP_016857515 (OMIM: 602597) PREDICTED: B-cell CLL/ (1352) 523 50.4 0.00016 XP_005277475 (OMIM: 602597) PREDICTED: B-cell CLL/ (1352) 523 50.4 0.00016 XP_005273028 (OMIM: 602597) PREDICTED: B-cell CLL/ (1426) 523 50.4 0.00017 NP_004317 (OMIM: 602597) B-cell CLL/lymphoma 9 pro (1426) 523 50.4 0.00017 NP_624361 (OMIM: 603024,614607) AT-rich interactiv (2068) 470 47.1 0.0024 NP_006006 (OMIM: 603024,614607) AT-rich interactiv (2285) 470 47.1 0.0026 XP_016866596 (OMIM: 135900,614556,614562) PREDICTE (2256) 454 46.1 0.0053 XP_005267126 (OMIM: 135900,614556,614562) PREDICTE (2289) 452 46.0 0.0058 XP_011528517 (OMIM: 607372) PREDICTED: mediator of ( 741) 427 44.1 0.0068 XP_016884306 (OMIM: 607372) PREDICTED: mediator of ( 749) 427 44.1 0.0069 XP_011528516 (OMIM: 607372) PREDICTED: mediator of ( 762) 427 44.1 0.007 NP_001003891 (OMIM: 607372) mediator of RNA polyme ( 788) 427 44.1 0.0072 XP_011537078 (OMIM: 147920,602113) PREDICTED: hist (5525) 463 46.9 0.0075 XP_006719679 (OMIM: 147920,602113) PREDICTED: hist (5536) 463 46.9 0.0075 XP_005269219 (OMIM: 147920,602113) PREDICTED: hist (5537) 463 46.9 0.0075 NP_003473 (OMIM: 147920,602113) histone-lysine N-m (5537) 463 46.9 0.0075 XP_006719677 (OMIM: 147920,602113) PREDICTED: hist (5540) 463 46.9 0.0075 XP_011537076 (OMIM: 147920,602113) PREDICTED: hist (5549) 463 46.9 0.0075 XP_011537075 (OMIM: 147920,602113) PREDICTED: hist (5552) 463 46.9 0.0075 XP_011537074 (OMIM: 147920,602113) PREDICTED: hist (5553) 463 46.9 0.0075 XP_011537073 (OMIM: 147920,602113) PREDICTED: hist (5555) 463 46.9 0.0075 XP_011537072 (OMIM: 147920,602113) PREDICTED: hist (5556) 463 46.9 0.0075 XP_016884307 (OMIM: 607372) PREDICTED: mediator of ( 707) 423 43.8 0.0078 XP_006724327 (OMIM: 607372) PREDICTED: mediator of ( 707) 423 43.8 0.0078 XP_016884308 (OMIM: 607372) PREDICTED: mediator of ( 707) 423 43.8 0.0078 XP_006724326 (OMIM: 607372) PREDICTED: mediator of ( 717) 423 43.9 0.0079 >>NP_001305169 (OMIM: 605299) nuclear receptor coactivat (2063 aa) initn: 13985 init1: 13985 opt: 13985 Z-score: 4836.8 bits: 908.6 E(85289): 0 Smith-Waterman score: 13985; 100.0% identity (100.0% similar) in 2063 aa overlap (1-2063:1-2063) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGISLDNSG ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_001 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KSD PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KSD APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KSD LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KSD QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR 1990 2000 2010 2020 2030 2040 2050 2060 pF1KSD PASASSSTKDITSAVQSKRRKSK ::::::::::::::::::::::: NP_001 PASASSSTKDITSAVQSKRRKSK 2050 2060 >>NP_054790 (OMIM: 605299) nuclear receptor coactivator (2063 aa) initn: 13985 init1: 13985 opt: 13985 Z-score: 4836.8 bits: 908.6 E(85289): 0 Smith-Waterman score: 13985; 100.0% identity (100.0% similar) in 2063 aa overlap (1-2063:1-2063) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGISLDNSG ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_054 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KSD PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KSD APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KSD LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KSD QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR 1990 2000 2010 2020 2030 2040 2050 2060 pF1KSD PASASSSTKDITSAVQSKRRKSK ::::::::::::::::::::::: NP_054 PASASSSTKDITSAVQSKRRKSK 2050 2060 >>XP_011527023 (OMIM: 605299) PREDICTED: nuclear recepto (2068 aa) initn: 12869 init1: 12869 opt: 13965 Z-score: 4829.9 bits: 907.3 E(85289): 0 Smith-Waterman score: 13965; 99.7% identity (99.8% similar) in 2068 aa overlap (1-2063:1-2068) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGI-----IR ::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQ 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD MPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQ 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD IMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD SPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD MQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDI 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD SAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 SAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGIN 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KSD VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGH 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KSD HFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQ 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KSD INIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQ 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KSD SNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KSD VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKE 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KSD QVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLL 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KSD DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNEL 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KSD CSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAA 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KSD LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQP 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KSD STIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLS 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KSD SRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSP 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KSD LLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQ 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KSD GLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVR 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KSD SIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKET 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KSD STTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHR 1990 2000 2010 2020 2030 2040 2040 2050 2060 pF1KSD KRSSRPASASSSTKDITSAVQSKRRKSK :::::::::::::::::::::::::::: XP_011 KRSSRPASASSSTKDITSAVQSKRRKSK 2050 2060 >>XP_006723818 (OMIM: 605299) PREDICTED: nuclear recepto (1975 aa) initn: 13395 init1: 13395 opt: 13395 Z-score: 4633.8 bits: 870.9 E(85289): 0 Smith-Waterman score: 13395; 99.9% identity (100.0% similar) in 1965 aa overlap (1-1965:1-1965) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGISLDNSG ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_006 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KSD PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KSD HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KSD QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KSD APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KSD VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KSD PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KSD APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KSD LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL ::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAKMLRVPTTEW 1930 1940 1950 1960 1970 1990 2000 2010 2020 2030 2040 pF1KSD QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR >>XP_011527028 (OMIM: 605299) PREDICTED: nuclear recepto (2057 aa) initn: 10445 init1: 10445 opt: 11780 Z-score: 4077.2 bits: 768.0 E(85289): 0 Smith-Waterman score: 13849; 99.2% identity (99.2% similar) in 2068 aa overlap (1-2063:1-2057) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGI-----IR ::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPS :::::::::::::::::::::::::::::::::: ::::::::::::::: XP_011 RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLG-----------AGQANPNFMQGQVPS 490 500 510 520 540 550 560 570 580 590 pF1KSD TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQ 530 540 550 560 570 580 600 610 620 630 640 650 pF1KSD AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL 590 600 610 620 630 640 660 670 680 690 700 710 pF1KSD MPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQ 650 660 670 680 690 700 720 730 740 750 760 770 pF1KSD IMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN 710 720 730 740 750 760 780 790 800 810 820 830 pF1KSD SPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA 770 780 790 800 810 820 840 850 860 870 880 890 pF1KSD MQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDI 830 840 850 860 870 880 900 910 920 930 940 950 pF1KSD SAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 SAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGIN 890 900 910 920 930 940 960 970 980 990 1000 1010 pF1KSD LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 950 960 970 980 990 1000 1020 1030 1040 1050 1060 1070 pF1KSD PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS 1010 1020 1030 1040 1050 1060 1080 1090 1100 1110 1120 1130 pF1KSD VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1070 1080 1090 1100 1110 1120 1140 1150 1160 1170 1180 1190 pF1KSD SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGH 1130 1140 1150 1160 1170 1180 1200 1210 1220 1230 1240 1250 pF1KSD HFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQ 1190 1200 1210 1220 1230 1240 1260 1270 1280 1290 1300 1310 pF1KSD INIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQ 1250 1260 1270 1280 1290 1300 1320 1330 1340 1350 1360 1370 pF1KSD SNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVL 1310 1320 1330 1340 1350 1360 1380 1390 1400 1410 1420 1430 pF1KSD VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKE 1370 1380 1390 1400 1410 1420 1440 1450 1460 1470 1480 1490 pF1KSD QVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLL 1430 1440 1450 1460 1470 1480 1500 1510 1520 1530 1540 1550 pF1KSD DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNEL 1490 1500 1510 1520 1530 1540 1560 1570 1580 1590 1600 1610 pF1KSD CSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAA 1550 1560 1570 1580 1590 1600 1620 1630 1640 1650 1660 1670 pF1KSD LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQP 1610 1620 1630 1640 1650 1660 1680 1690 1700 1710 1720 1730 pF1KSD STIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLS 1670 1680 1690 1700 1710 1720 1740 1750 1760 1770 1780 1790 pF1KSD SRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSP 1730 1740 1750 1760 1770 1780 1800 1810 1820 1830 1840 1850 pF1KSD LLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQ 1790 1800 1810 1820 1830 1840 1860 1870 1880 1890 1900 1910 pF1KSD GLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVR 1850 1860 1870 1880 1890 1900 1920 1930 1940 1950 1960 1970 pF1KSD SIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKET 1910 1920 1930 1940 1950 1960 1980 1990 2000 2010 2020 2030 pF1KSD STTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHR 1970 1980 1990 2000 2010 2020 2040 2050 2060 pF1KSD KRSSRPASASSSTKDITSAVQSKRRKSK :::::::::::::::::::::::::::: XP_011 KRSSRPASASSSTKDITSAVQSKRRKSK 2030 2040 2050 >>XP_011527029 (OMIM: 605299) PREDICTED: nuclear recepto (2056 aa) initn: 10420 init1: 10420 opt: 11754 Z-score: 4068.3 bits: 766.4 E(85289): 0 Smith-Waterman score: 13842; 99.1% identity (99.2% similar) in 2068 aa overlap (1-2063:1-2056) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGI-----IR ::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_011 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPS ::::::::::::::::::::::::::::::::::: ::::::::::::: XP_011 RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGG------------QANPNFMQGQVPS 490 500 510 520 540 550 560 570 580 590 pF1KSD TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQ 530 540 550 560 570 580 600 610 620 630 640 650 pF1KSD AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQL 590 600 610 620 630 640 660 670 680 690 700 710 pF1KSD MPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQ 650 660 670 680 690 700 720 730 740 750 760 770 pF1KSD IMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN 710 720 730 740 750 760 780 790 800 810 820 830 pF1KSD SPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQA 770 780 790 800 810 820 840 850 860 870 880 890 pF1KSD MQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDI 830 840 850 860 870 880 900 910 920 930 940 950 pF1KSD SAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 SAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGIN 890 900 910 920 930 940 960 970 980 990 1000 1010 pF1KSD LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 950 960 970 980 990 1000 1020 1030 1040 1050 1060 1070 pF1KSD PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGS 1010 1020 1030 1040 1050 1060 1080 1090 1100 1110 1120 1130 pF1KSD VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1070 1080 1090 1100 1110 1120 1140 1150 1160 1170 1180 1190 pF1KSD SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGH 1130 1140 1150 1160 1170 1180 1200 1210 1220 1230 1240 1250 pF1KSD HFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQ 1190 1200 1210 1220 1230 1240 1260 1270 1280 1290 1300 1310 pF1KSD INIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQ 1250 1260 1270 1280 1290 1300 1320 1330 1340 1350 1360 1370 pF1KSD SNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVL 1310 1320 1330 1340 1350 1360 1380 1390 1400 1410 1420 1430 pF1KSD VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKE 1370 1380 1390 1400 1410 1420 1440 1450 1460 1470 1480 1490 pF1KSD QVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLL 1430 1440 1450 1460 1470 1480 1500 1510 1520 1530 1540 1550 pF1KSD DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNEL 1490 1500 1510 1520 1530 1540 1560 1570 1580 1590 1600 1610 pF1KSD CSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAA 1550 1560 1570 1580 1590 1600 1620 1630 1640 1650 1660 1670 pF1KSD LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQP 1610 1620 1630 1640 1650 1660 1680 1690 1700 1710 1720 1730 pF1KSD STIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLS 1670 1680 1690 1700 1710 1720 1740 1750 1760 1770 1780 1790 pF1KSD SRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSP 1730 1740 1750 1760 1770 1780 1800 1810 1820 1830 1840 1850 pF1KSD LLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQ 1790 1800 1810 1820 1830 1840 1860 1870 1880 1890 1900 1910 pF1KSD GLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVR 1850 1860 1870 1880 1890 1900 1920 1930 1940 1950 1960 1970 pF1KSD SIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKET 1910 1920 1930 1940 1950 1960 1980 1990 2000 2010 2020 2030 pF1KSD STTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHR 1970 1980 1990 2000 2010 2020 2040 2050 2060 pF1KSD KRSSRPASASSSTKDITSAVQSKRRKSK :::::::::::::::::::::::::::: XP_011 KRSSRPASASSSTKDITSAVQSKRRKSK 2030 2040 2050 >>XP_016883233 (OMIM: 605299) PREDICTED: nuclear recepto (2051 aa) initn: 10420 init1: 10420 opt: 10674 Z-score: 3696.2 bits: 697.5 E(85289): 3.8e-199 Smith-Waterman score: 13862; 99.4% identity (99.4% similar) in 2063 aa overlap (1-2063:1-2051) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATT :::::::::::::::::::::::::::::: :::::::::::::::::: XP_016 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGG------------QANPNFMQGQVPSTTATT 490 500 510 520 550 560 570 580 590 600 pF1KSD PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSG 530 540 550 560 570 580 610 620 630 640 650 660 pF1KSD VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQ 590 600 610 620 630 640 670 680 690 700 710 720 pF1KSD MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 650 660 670 680 690 700 730 740 750 760 770 780 pF1KSD MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQV 710 720 730 740 750 760 790 800 810 820 830 840 pF1KSD MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNS 770 780 790 800 810 820 850 860 870 880 890 900 pF1KSD ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHF 830 840 850 860 870 880 910 920 930 940 950 960 pF1KSD GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGISLDNSG ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_016 GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSG 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KSD PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQ 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KSD PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMV 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KSD SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KSD PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNV 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KSD AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPL 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KSD PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1250 1260 1270 1280 1290 1300 1330 1340 1350 1360 1370 1380 pF1KSD TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1310 1320 1330 1340 1350 1360 1390 1400 1410 1420 1430 1440 pF1KSD LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIE 1370 1380 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KSD LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGA 1430 1440 1450 1460 1470 1480 1510 1520 1530 1540 1550 1560 pF1KSD PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLV 1490 1500 1510 1520 1530 1540 1570 1580 1590 1600 1610 1620 pF1KSD HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHL 1550 1560 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KSD QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPA 1610 1620 1630 1640 1650 1660 1690 1700 1710 1720 1730 1740 pF1KSD APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATP 1670 1680 1690 1700 1710 1720 1750 1760 1770 1780 1790 1800 pF1KSD VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNS 1730 1740 1750 1760 1770 1780 1810 1820 1830 1840 1850 1860 pF1KSD PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTT 1790 1800 1810 1820 1830 1840 1870 1880 1890 1900 1910 1920 pF1KSD APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALPTSVRSIVTT 1850 1860 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KSD LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELLPSIAPSQNLVSKETSTTAL 1910 1920 1930 1940 1950 1960 1990 2000 2010 2020 2030 2040 pF1KSD QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSR 1970 1980 1990 2000 2010 2020 2050 2060 pF1KSD PASASSSTKDITSAVQSKRRKSK ::::::::::::::::::::::: XP_016 PASASSSTKDITSAVQSKRRKSK 2030 2040 2050 >>XP_016883234 (OMIM: 605299) PREDICTED: nuclear recepto (2039 aa) initn: 12475 init1: 10349 opt: 10612 Z-score: 3674.9 bits: 693.6 E(85289): 5.9e-198 Smith-Waterman score: 13456; 96.6% identity (96.8% similar) in 2082 aa overlap (1-2063:1-2039) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPA ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGP--------- 130 140 150 160 170 190 200 210 220 230 240 pF1KSD TVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH :::::::::::::::::::::::::: XP_016 ----------------------------------DAMDPLLSGLHIQQQSHPSGSLAPPH 180 190 250 260 270 280 290 300 pF1KSD HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 200 210 220 230 240 250 310 320 330 340 350 360 pF1KSD GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KSD PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ 320 330 340 350 360 370 430 440 450 460 470 480 pF1KSD PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMV 380 390 400 410 420 430 490 500 510 520 pF1KSD QQGNVPPNFMVMQQQPPNQGPQSLHPGLG--GMPKRLP---PG---------FS-----A ::::::::::::::::::::::::::::: . :. : : :: . XP_016 QQGNVPPNFMVMQQQPPNQGPQSLHPGLGEKSEPSNLAVAWPQITFREQIAIFSLACSKS 440 450 460 470 480 490 530 540 550 560 570 580 pF1KSD GQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQ 500 510 520 530 540 550 590 600 610 620 630 640 pF1KSD PSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGT 560 570 580 590 600 610 650 660 670 680 690 700 pF1KSD LNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGP 620 630 640 650 660 670 710 720 730 740 750 760 pF1KSD QGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQ 680 690 700 710 720 730 770 780 790 800 810 820 pF1KSD MSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDV 740 750 760 770 780 790 830 840 850 860 870 880 pF1KSD SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVT 800 810 820 830 840 850 890 900 910 920 930 940 pF1KSD LTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLE 860 870 880 890 900 910 950 960 970 980 990 1000 pF1KSD EADQPPLPGEQGISLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPP :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: XP_016 EADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPP 920 930 940 950 960 970 1010 1020 1030 1040 1050 1060 pF1KSD QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPL 980 990 1000 1010 1020 1030 1070 1080 1090 1100 1110 1120 pF1KSD NPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNP 1040 1050 1060 1070 1080 1090 1130 1140 1150 1160 1170 1180 pF1KSD SSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATP 1100 1110 1120 1130 1140 1150 1190 1200 1210 1220 1230 1240 pF1KSD QQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSP 1160 1170 1180 1190 1200 1210 1250 1260 1270 1280 1290 1300 pF1KSD ERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQ 1220 1230 1240 1250 1260 1270 1310 1320 1330 1340 1350 1360 pF1KSD THKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTN 1280 1290 1300 1310 1320 1330 1370 1380 1390 1400 1410 1420 pF1KSD AALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNV 1340 1350 1360 1370 1380 1390 1430 1440 1450 1460 1470 1480 pF1KSD PQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVS 1400 1410 1420 1430 1440 1450 1490 1500 1510 1520 1530 1540 pF1KSD PAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSK 1460 1470 1480 1490 1500 1510 1550 1560 1570 1580 1590 1600 pF1KSD EPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFV 1520 1530 1540 1550 1560 1570 1610 1620 1630 1640 1650 1660 pF1KSD TSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFI 1580 1590 1600 1610 1620 1630 1670 1680 1690 1700 1710 1720 pF1KSD NSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSS 1640 1650 1660 1670 1680 1690 1730 1740 1750 1760 1770 1780 pF1KSD PAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQ 1700 1710 1720 1730 1740 1750 1790 1800 1810 1820 1830 1840 pF1KSD NTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEK 1760 1770 1780 1790 1800 1810 1850 1860 1870 1880 1890 1900 pF1KSD GEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASA 1820 1830 1840 1850 1860 1870 1910 1920 1930 1940 1950 1960 pF1KSD GPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGSHPELL 1880 1890 1900 1910 1920 1930 1970 1980 1990 2000 2010 2020 pF1KSD PSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTE 1940 1950 1960 1970 1980 1990 2030 2040 2050 2060 pF1KSD EPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK :::::::::::::::::::::::::::::::::::::::::: XP_016 EPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK 2000 2010 2020 2030 >>XP_016883228 (OMIM: 605299) PREDICTED: nuclear recepto (2087 aa) initn: 12767 init1: 10349 opt: 10608 Z-score: 3673.4 bits: 693.3 E(85289): 7.2e-198 Smith-Waterman score: 13831; 98.5% identity (98.7% similar) in 2087 aa overlap (1-2063:1-2087) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGI-----IR ::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_016 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 430 440 450 460 470 480 480 490 500 510 520 pF1KSD RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLG--GMPKRLP---PG---------FS- :::::::::::::::::::::::::::::::::: . :. : : :: XP_016 RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGEKSEPSNLAVAWPQITFREQIAIFSL 490 500 510 520 530 540 530 540 550 560 570 pF1KSD ----AGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGP .::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACSKSGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMV 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHN 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD QMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMV 730 740 750 760 770 780 760 770 780 790 800 810 pF1KSD QFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQ 790 800 810 820 830 840 820 830 840 850 860 870 pF1KSD MMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPV 850 860 870 880 890 900 880 890 900 910 920 930 pF1KSD NKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTR 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD PAGLEEADQPPLPGEQGISLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAP ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 PAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAP 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KSD PPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KSD PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQE 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KSD SPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSAT 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD QGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSE 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD ISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSN 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KSD FATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTL 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KSD ASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNK 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD ESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEEN 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KSD KNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQD 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 1590 pF1KSD LSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQ 1570 1580 1590 1600 1610 1620 1600 1610 1620 1630 1640 1650 pF1KSD ITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFI 1630 1640 1650 1660 1670 1680 1660 1670 1680 1690 1700 1710 pF1KSD TPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPN 1690 1700 1710 1720 1730 1740 1720 1730 1740 1750 1760 1770 pF1KSD ALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVN 1750 1760 1770 1780 1790 1800 1780 1790 1800 1810 1820 1830 pF1KSD TSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVT 1810 1820 1830 1840 1850 1860 1840 1850 1860 1870 1880 1890 pF1KSD GSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP 1870 1880 1890 1900 1910 1920 1900 1910 1920 1930 1940 1950 pF1KSD GTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGS 1930 1940 1950 1960 1970 1980 1960 1970 1980 1990 2000 2010 pF1KSD HPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRR 1990 2000 2010 2020 2030 2040 2020 2030 2040 2050 2060 pF1KSD NSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK 2050 2060 2070 2080 >>XP_016883229 (OMIM: 605299) PREDICTED: nuclear recepto (2087 aa) initn: 12767 init1: 10349 opt: 10608 Z-score: 3673.4 bits: 693.3 E(85289): 7.2e-198 Smith-Waterman score: 13831; 98.5% identity (98.7% similar) in 2087 aa overlap (1-2063:1-2087) 10 20 30 40 50 60 pF1KSD MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLR 70 80 90 100 110 120 130 140 150 160 170 pF1KSD DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGI-----IR ::::::::::::::::::::::::::::::::::::::::::::::::::::: :: XP_016 DLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIFFLGIIR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQ 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 430 440 450 460 470 480 480 490 500 510 520 pF1KSD RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLG--GMPKRLP---PG---------FS- :::::::::::::::::::::::::::::::::: . :. : : :: XP_016 RNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGEKSEPSNLAVAWPQITFREQIAIFSL 490 500 510 520 530 540 530 540 550 560 570 pF1KSD ----AGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGP .::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACSKSGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMV 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHN 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD QMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMV 730 740 750 760 770 780 760 770 780 790 800 810 pF1KSD QFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQ 790 800 810 820 830 840 820 830 840 850 860 870 pF1KSD MMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPV 850 860 870 880 890 900 880 890 900 910 920 930 pF1KSD NKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTR 910 920 930 940 950 960 940 950 960 970 980 990 pF1KSD PAGLEEADQPPLPGEQGISLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAP ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 PAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAP 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KSD PPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KSD PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQE 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KSD SPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSAT 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KSD QGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSE 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KSD ISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSN 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KSD FATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTL 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KSD ASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNK 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KSD ESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEEN 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KSD KNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQD 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 1590 pF1KSD LSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQ 1570 1580 1590 1600 1610 1620 1600 1610 1620 1630 1640 1650 pF1KSD ITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFI 1630 1640 1650 1660 1670 1680 1660 1670 1680 1690 1700 1710 pF1KSD TPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPN 1690 1700 1710 1720 1730 1740 1720 1730 1740 1750 1760 1770 pF1KSD ALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSSSPAPNIQTGRPLVLSSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVN 1750 1760 1770 1780 1790 1800 1780 1790 1800 1810 1820 1830 pF1KSD TSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSKGKGKVDKIGQILLTKACKKVT 1810 1820 1830 1840 1850 1860 1840 1850 1860 1870 1880 1890 pF1KSD GSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLEKGEEQYGADGETEGQGLDTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP 1870 1880 1890 1900 1910 1920 1900 1910 1920 1930 1940 1950 pF1KSD GTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTASAGPSLPGGALPTSVRSIVTTLVPSELISAVPTTKSNHGGIASESLAGGLVEEKVGS 1930 1940 1950 1960 1970 1980 1960 1970 1980 1990 2000 2010 pF1KSD HPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRR 1990 2000 2010 2020 2030 2040 2020 2030 2040 2050 2060 pF1KSD NSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK 2050 2060 2070 2080 2063 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:31:08 2016 done: Thu Nov 3 00:31:12 2016 Total Scan time: 24.760 Total Display time: 1.780 Function used was FASTA [36.3.4 Apr, 2011]