FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0198, 496 aa 1>>>pF1KSDA0198 496 - 496 aa - 496 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7079+/-0.000414; mu= 4.9681+/- 0.025 mean_var=417.5215+/-94.795, 0's: 0 Z-trim(121.6): 1264 B-trim: 2196 in 1/56 Lambda= 0.062767 statistics sampled from 36516 (38391) to 36516 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.45), width: 16 Scan time: 10.350 The best scores are: opt bits E(85289) NP_002648 (OMIM: 604866) zinc finger protein PLAGL ( 496) 3453 327.2 6.5e-89 XP_005260493 (OMIM: 604866) PREDICTED: zinc finger ( 496) 3453 327.2 6.5e-89 XP_011527166 (OMIM: 604866) PREDICTED: zinc finger ( 496) 3453 327.2 6.5e-89 XP_011527165 (OMIM: 604866) PREDICTED: zinc finger ( 496) 3453 327.2 6.5e-89 NP_002646 (OMIM: 181030,603026) zinc finger protei ( 500) 1452 146.0 2.3e-34 XP_016869065 (OMIM: 181030,603026) PREDICTED: zinc ( 500) 1452 146.0 2.3e-34 NP_001108106 (OMIM: 181030,603026) zinc finger pro ( 500) 1452 146.0 2.3e-34 XP_011515846 (OMIM: 181030,603026) PREDICTED: zinc ( 418) 1278 130.2 1.2e-29 NP_001108107 (OMIM: 181030,603026) zinc finger pro ( 418) 1278 130.2 1.2e-29 XP_016869066 (OMIM: 181030,603026) PREDICTED: zinc ( 418) 1278 130.2 1.2e-29 NP_001275973 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275976 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275971 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001074422 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275974 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001074420 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001304091 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_006709 (OMIM: 601410,603044) zinc finger protei ( 463) 1260 128.6 3.8e-29 NP_001074423 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001304088 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275975 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001074421 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001304086 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001304090 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275977 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275972 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275978 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001304085 (OMIM: 601410,603044) zinc finger pro ( 463) 1260 128.6 3.8e-29 NP_001275967 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001275969 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001275970 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001304087 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001074424 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001304089 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001275968 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001074425 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001275966 (OMIM: 601410,603044) zinc finger pro ( 411) 1096 113.7 1e-24 NP_001303926 (OMIM: 606957) zinc finger protein 25 ( 487) 426 53.1 2.1e-06 NP_001303927 (OMIM: 606957) zinc finger protein 25 ( 487) 426 53.1 2.1e-06 NP_001303925 (OMIM: 606957) zinc finger protein 25 ( 531) 426 53.2 2.2e-06 NP_258429 (OMIM: 606957) zinc finger protein 257 i ( 563) 426 53.2 2.3e-06 NP_001255984 (OMIM: 607022) transcriptional repres ( 299) 417 52.0 2.9e-06 NP_001255979 (OMIM: 607022) transcriptional repres ( 422) 418 52.3 3.2e-06 NP_001255983 (OMIM: 607022) transcriptional repres ( 403) 417 52.2 3.4e-06 NP_001255978 (OMIM: 607022) transcriptional repres ( 460) 417 52.3 3.6e-06 NP_001255974 (OMIM: 607022) transcriptional repres ( 627) 418 52.6 4e-06 NP_001255976 (OMIM: 607022) transcriptional repres ( 573) 417 52.4 4.1e-06 NP_001255971 (OMIM: 607022) transcriptional repres ( 662) 417 52.5 4.4e-06 NP_542185 (OMIM: 607022) transcriptional repressor ( 663) 417 52.5 4.4e-06 NP_001255969 (OMIM: 607022) transcriptional repres ( 663) 417 52.5 4.4e-06 >>NP_002648 (OMIM: 604866) zinc finger protein PLAGL2 [H (496 aa) initn: 3453 init1: 3453 opt: 3453 Z-score: 1717.2 bits: 327.2 E(85289): 6.5e-89 Smith-Waterman score: 3453; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KSD MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT 430 440 450 460 470 480 490 pF1KSD SGLSSTTLPRFHQAFQ :::::::::::::::: NP_002 SGLSSTTLPRFHQAFQ 490 >>XP_005260493 (OMIM: 604866) PREDICTED: zinc finger pro (496 aa) initn: 3453 init1: 3453 opt: 3453 Z-score: 1717.2 bits: 327.2 E(85289): 6.5e-89 Smith-Waterman score: 3453; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KSD MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT 430 440 450 460 470 480 490 pF1KSD SGLSSTTLPRFHQAFQ :::::::::::::::: XP_005 SGLSSTTLPRFHQAFQ 490 >>XP_011527166 (OMIM: 604866) PREDICTED: zinc finger pro (496 aa) initn: 3453 init1: 3453 opt: 3453 Z-score: 1717.2 bits: 327.2 E(85289): 6.5e-89 Smith-Waterman score: 3453; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KSD MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT 430 440 450 460 470 480 490 pF1KSD SGLSSTTLPRFHQAFQ :::::::::::::::: XP_011 SGLSSTTLPRFHQAFQ 490 >>XP_011527165 (OMIM: 604866) PREDICTED: zinc finger pro (496 aa) initn: 3453 init1: 3453 opt: 3453 Z-score: 1717.2 bits: 327.2 E(85289): 6.5e-89 Smith-Waterman score: 3453; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KSD MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFT 430 440 450 460 470 480 490 pF1KSD SGLSSTTLPRFHQAFQ :::::::::::::::: XP_011 SGLSSTTLPRFHQAFQ 490 >>NP_002646 (OMIM: 181030,603026) zinc finger protein PL (500 aa) initn: 1642 init1: 1232 opt: 1452 Z-score: 737.9 bits: 146.0 E(85289): 2.3e-34 Smith-Waterman score: 1709; 52.0% identity (75.2% similar) in 504 aa overlap (6-496:3-500) 10 20 30 40 50 60 pF1KSD MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL : .: ...... ..: : :: :.. . . :.. :.. :::. :: NP_002 MATVIPGDLSEVRDTQKV--PSGKRKRG-ETKPRKNFPCQLCDKAFNSVEKLKVHSY 10 20 30 40 50 70 80 90 100 110 120 pF1KSD PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH . .:::.: : : :::.::::: ::::::: .: :.: ::.:::::::::.:::.:: NP_002 SHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR :::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.:. NP_002 DPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::.:: NP_002 KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA ::.:::::.::::::.: ..:. .: .:.:: ::. . : ... .: : . : ...:.. NP_002 SHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELL-SKPFTNTLQLNLYNT 240 250 260 270 280 290 310 320 330 340 350 pF1KSD HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-LP- . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: : NP_002 PFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEALC : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. : NP_002 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN 360 370 380 390 400 410 410 420 430 440 450 460 pF1KSD AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLN . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. .. NP_002 TPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIG 420 430 440 450 460 470 470 480 490 pF1KSD FGPLHSLPPVFTSGLS-STTLPRFHQAFQ .: :::: .:::.:: :::::::::::: NP_002 LGSLHSLSAAFTSSLSTSTTLPRFHQAFQ 480 490 500 >>XP_016869065 (OMIM: 181030,603026) PREDICTED: zinc fin (500 aa) initn: 1642 init1: 1232 opt: 1452 Z-score: 737.9 bits: 146.0 E(85289): 2.3e-34 Smith-Waterman score: 1709; 52.0% identity (75.2% similar) in 504 aa overlap (6-496:3-500) 10 20 30 40 50 60 pF1KSD MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL : .: ...... ..: : :: :.. . . :.. :.. :::. :: XP_016 MATVIPGDLSEVRDTQKV--PSGKRKRG-ETKPRKNFPCQLCDKAFNSVEKLKVHSY 10 20 30 40 50 70 80 90 100 110 120 pF1KSD PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH . .:::.: : : :::.::::: ::::::: .: :.: ::.:::::::::.:::.:: XP_016 SHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR :::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.:. XP_016 DPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::.:: XP_016 KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA ::.:::::.::::::.: ..:. .: .:.:: ::. . : ... .: : . : ...:.. XP_016 SHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELL-SKPFTNTLQLNLYNT 240 250 260 270 280 290 310 320 330 340 350 pF1KSD HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-LP- . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: : XP_016 PFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEALC : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. : XP_016 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN 360 370 380 390 400 410 410 420 430 440 450 460 pF1KSD AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLN . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. .. XP_016 TPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIG 420 430 440 450 460 470 470 480 490 pF1KSD FGPLHSLPPVFTSGLS-STTLPRFHQAFQ .: :::: .:::.:: :::::::::::: XP_016 LGSLHSLSAAFTSSLSTSTTLPRFHQAFQ 480 490 500 >>NP_001108106 (OMIM: 181030,603026) zinc finger protein (500 aa) initn: 1642 init1: 1232 opt: 1452 Z-score: 737.9 bits: 146.0 E(85289): 2.3e-34 Smith-Waterman score: 1709; 52.0% identity (75.2% similar) in 504 aa overlap (6-496:3-500) 10 20 30 40 50 60 pF1KSD MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL : .: ...... ..: : :: :.. . . :.. :.. :::. :: NP_001 MATVIPGDLSEVRDTQKV--PSGKRKRG-ETKPRKNFPCQLCDKAFNSVEKLKVHSY 10 20 30 40 50 70 80 90 100 110 120 pF1KSD PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH . .:::.: : : :::.::::: ::::::: .: :.: ::.:::::::::.:::.:: NP_001 SHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR :::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.:. NP_001 DPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::.:: NP_001 KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA ::.:::::.::::::.: ..:. .: .:.:: ::. . : ... .: : . : ...:.. NP_001 SHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELL-SKPFTNTLQLNLYNT 240 250 260 270 280 290 310 320 330 340 350 pF1KSD HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-LP- . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: : NP_001 PFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEALC : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. : NP_001 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN 360 370 380 390 400 410 410 420 430 440 450 460 pF1KSD AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLN . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. .. NP_001 TPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIG 420 430 440 450 460 470 470 480 490 pF1KSD FGPLHSLPPVFTSGLS-STTLPRFHQAFQ .: :::: .:::.:: :::::::::::: NP_001 LGSLHSLSAAFTSSLSTSTTLPRFHQAFQ 480 490 500 >>XP_011515846 (OMIM: 181030,603026) PREDICTED: zinc fin (418 aa) initn: 1557 init1: 1088 opt: 1278 Z-score: 653.5 bits: 130.2 E(85289): 1.2e-29 Smith-Waterman score: 1535; 55.1% identity (77.7% similar) in 421 aa overlap (89-496:1-418) 60 70 80 90 100 110 pF1KSD SLPQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQ ::::: .: :.: ::.:::::::::.:::. XP_011 MATHSPEKTHKCNYCEKMFHRKDHLKNHLH 10 20 30 120 130 140 150 160 170 pF1KSD THDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAH :::::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.: XP_011 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD SRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHV . . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::. XP_011 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM 100 110 120 130 140 150 240 250 260 270 280 290 pF1KSD KKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMY ::::.:::::.::::::.: ..:. .: .:.:: ::. . : ... .: : . : ...: XP_011 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELL-SKPFTNTLQLNLY 160 170 180 190 200 300 310 320 330 340 350 pF1KSD GAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-L .. . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: XP_011 NTPFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQ 210 220 230 240 250 260 360 370 380 390 400 pF1KSD P-KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEA : : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. XP_011 PLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDP 270 280 290 300 310 320 410 420 430 440 450 460 pF1KSD LCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGP : . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. XP_011 LNTPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANT 330 340 350 360 370 380 470 480 490 pF1KSD LNFGPLHSLPPVFTSGLS-STTLPRFHQAFQ ...: :::: .:::.:: :::::::::::: XP_011 IGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ 390 400 410 >>NP_001108107 (OMIM: 181030,603026) zinc finger protein (418 aa) initn: 1557 init1: 1088 opt: 1278 Z-score: 653.5 bits: 130.2 E(85289): 1.2e-29 Smith-Waterman score: 1535; 55.1% identity (77.7% similar) in 421 aa overlap (89-496:1-418) 60 70 80 90 100 110 pF1KSD SLPQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQ ::::: .: :.: ::.:::::::::.:::. NP_001 MATHSPEKTHKCNYCEKMFHRKDHLKNHLH 10 20 30 120 130 140 150 160 170 pF1KSD THDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAH :::::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.: NP_001 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD SRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHV . . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::. NP_001 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM 100 110 120 130 140 150 240 250 260 270 280 290 pF1KSD KKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMY ::::.:::::.::::::.: ..:. .: .:.:: ::. . : ... .: : . : ...: NP_001 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELL-SKPFTNTLQLNLY 160 170 180 190 200 300 310 320 330 340 350 pF1KSD GAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-L .. . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: NP_001 NTPFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQ 210 220 230 240 250 260 360 370 380 390 400 pF1KSD P-KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEA : : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. NP_001 PLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDP 270 280 290 300 310 320 410 420 430 440 450 460 pF1KSD LCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGP : . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. NP_001 LNTPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANT 330 340 350 360 370 380 470 480 490 pF1KSD LNFGPLHSLPPVFTSGLS-STTLPRFHQAFQ ...: :::: .:::.:: :::::::::::: NP_001 IGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ 390 400 410 >>XP_016869066 (OMIM: 181030,603026) PREDICTED: zinc fin (418 aa) initn: 1557 init1: 1088 opt: 1278 Z-score: 653.5 bits: 130.2 E(85289): 1.2e-29 Smith-Waterman score: 1535; 55.1% identity (77.7% similar) in 421 aa overlap (89-496:1-418) 60 70 80 90 100 110 pF1KSD SLPQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQ ::::: .: :.: ::.:::::::::.:::. XP_016 MATHSPEKTHKCNYCEKMFHRKDHLKNHLH 10 20 30 120 130 140 150 160 170 pF1KSD THDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAH :::::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.: XP_016 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH 40 50 60 70 80 90 180 190 200 210 220 230 pF1KSD SRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHV . . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::. XP_016 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM 100 110 120 130 140 150 240 250 260 270 280 290 pF1KSD KKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMY ::::.:::::.::::::.: ..:. .: .:.:: ::. . : ... .: : . : ...: XP_016 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELL-SKPFTNTLQLNLY 160 170 180 190 200 300 310 320 330 340 350 pF1KSD GAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-L .. . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: XP_016 NTPFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQ 210 220 230 240 250 260 360 370 380 390 400 pF1KSD P-KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEA : : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. XP_016 PLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDP 270 280 290 300 310 320 410 420 430 440 450 460 pF1KSD LCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGP : . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. XP_016 LNTPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANT 330 340 350 360 370 380 470 480 490 pF1KSD LNFGPLHSLPPVFTSGLS-STTLPRFHQAFQ ...: :::: .:::.:: :::::::::::: XP_016 IGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ 390 400 410 496 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:35:40 2016 done: Thu Nov 3 00:35:41 2016 Total Scan time: 10.350 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]