Result of FASTA (omim) for
pF1KSDA0199
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0199, 1279 aa
1>>>pF1KSDA0199 1279 - 1279 aa - 1279 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4071+/-0.000369; mu= 10.4730+/- 0.023
mean_var=218.4636+/-44.192, 0's: 0 Z-trim(120.5): 106 B-trim: 0 in 0/58
Lambda= 0.086773
statistics sampled from 35777 (35905) to 35777 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.421), width: 16
Scan time: 15.080
The best scores are: opt bits E(85289)
NP_036367 (OMIM: 601510) sterol regulatory element (1279) 8711 1104.4 0
XP_016861407 (OMIM: 601510) PREDICTED: sterol regu (1279) 8711 1104.4 0
XP_011531803 (OMIM: 601510) PREDICTED: sterol regu (1279) 8711 1104.4 0
XP_005265024 (OMIM: 601510) PREDICTED: sterol regu (1278) 8692 1102.0 0
XP_016861408 (OMIM: 601510) PREDICTED: sterol regu (1049) 7120 905.1 0
XP_016861409 (OMIM: 601510) PREDICTED: sterol regu (1048) 7101 902.8 0
XP_005265025 (OMIM: 601510) PREDICTED: sterol regu (1024) 6961 885.2 0
NP_001306973 (OMIM: 601510) sterol regulatory elem (1023) 6942 882.8 0
XP_011531804 (OMIM: 601510) PREDICTED: sterol regu ( 898) 6163 785.3 0
XP_005265028 (OMIM: 601510) PREDICTED: sterol regu ( 887) 6104 777.9 0
XP_016861410 (OMIM: 601510) PREDICTED: sterol regu ( 886) 6085 775.5 0
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 299 51.0 2.7e-05
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 299 51.0 2.8e-05
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 299 51.0 3e-05
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 299 51.1 3.1e-05
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 299 51.1 3.1e-05
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 299 51.1 3.2e-05
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 299 51.1 3.2e-05
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 299 51.1 3.2e-05
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 299 51.1 3.2e-05
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 299 51.1 3.2e-05
XP_011524317 (OMIM: 257220,607623) PREDICTED: Niem (1148) 277 48.5 0.00031
XP_016881276 (OMIM: 257220,607623) PREDICTED: Niem (1256) 277 48.6 0.00033
XP_016881275 (OMIM: 257220,607623) PREDICTED: Niem (1264) 277 48.6 0.00033
XP_016881274 (OMIM: 257220,607623) PREDICTED: Niem (1273) 277 48.6 0.00034
XP_006722542 (OMIM: 257220,607623) PREDICTED: Niem (1273) 277 48.6 0.00034
NP_000262 (OMIM: 257220,607623) Niemann-Pick C1 pr (1278) 277 48.6 0.00034
XP_016881273 (OMIM: 257220,607623) PREDICTED: Niem (1281) 277 48.6 0.00034
XP_005258336 (OMIM: 257220,607623) PREDICTED: Niem (1286) 277 48.6 0.00034
XP_005258335 (OMIM: 257220,607623) PREDICTED: Niem (1295) 277 48.6 0.00034
XP_005258334 (OMIM: 257220,607623) PREDICTED: Niem (1303) 277 48.6 0.00034
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 258 45.7 0.00066
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 258 45.7 0.00066
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 258 45.7 0.00066
XP_011513630 (OMIM: 608010) PREDICTED: Niemann-Pic ( 785) 254 45.5 0.0017
NP_001095118 (OMIM: 608010) Niemann-Pick C1-like p (1332) 254 45.7 0.0025
NP_037521 (OMIM: 608010) Niemann-Pick C1-like prot (1359) 254 45.7 0.0026
NP_001077074 (OMIM: 109400,601309,605462,610828) p (1296) 243 44.3 0.0065
NP_001077075 (OMIM: 109400,601309,605462,610828) p (1296) 243 44.3 0.0065
NP_001077073 (OMIM: 109400,601309,605462,610828) p (1296) 243 44.3 0.0065
NP_001077076 (OMIM: 109400,601309,605462,610828) p (1296) 243 44.3 0.0065
NP_001077071 (OMIM: 109400,601309,605462,610828) p (1381) 243 44.3 0.0068
NP_001077072 (OMIM: 109400,601309,605462,610828) p (1446) 243 44.4 0.007
NP_000255 (OMIM: 109400,601309,605462,610828) prot (1447) 243 44.4 0.007
NP_001159764 (OMIM: 109400,155255,603673,605462) p (1146) 238 43.6 0.0092
NP_003729 (OMIM: 109400,155255,603673,605462) prot (1203) 238 43.7 0.0095
>>NP_036367 (OMIM: 601510) sterol regulatory element-bin (1279 aa)
initn: 8711 init1: 8711 opt: 8711 Z-score: 5902.5 bits: 1104.4 E(85289): 0
Smith-Waterman score: 8711; 100.0% identity (100.0% similar) in 1279 aa overlap (1-1279:1-1279)
10 20 30 40 50 60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
1210 1220 1230 1240 1250 1260
1270
pF1KSD NFGSELSLVYVPSVLEKLD
:::::::::::::::::::
NP_036 NFGSELSLVYVPSVLEKLD
1270
>>XP_016861407 (OMIM: 601510) PREDICTED: sterol regulato (1279 aa)
initn: 8711 init1: 8711 opt: 8711 Z-score: 5902.5 bits: 1104.4 E(85289): 0
Smith-Waterman score: 8711; 100.0% identity (100.0% similar) in 1279 aa overlap (1-1279:1-1279)
10 20 30 40 50 60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
1210 1220 1230 1240 1250 1260
1270
pF1KSD NFGSELSLVYVPSVLEKLD
:::::::::::::::::::
XP_016 NFGSELSLVYVPSVLEKLD
1270
>>XP_011531803 (OMIM: 601510) PREDICTED: sterol regulato (1279 aa)
initn: 8711 init1: 8711 opt: 8711 Z-score: 5902.5 bits: 1104.4 E(85289): 0
Smith-Waterman score: 8711; 100.0% identity (100.0% similar) in 1279 aa overlap (1-1279:1-1279)
10 20 30 40 50 60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
1210 1220 1230 1240 1250 1260
1270
pF1KSD NFGSELSLVYVPSVLEKLD
:::::::::::::::::::
XP_011 NFGSELSLVYVPSVLEKLD
1270
>>XP_005265024 (OMIM: 601510) PREDICTED: sterol regulato (1278 aa)
initn: 5619 init1: 5566 opt: 8692 Z-score: 5889.7 bits: 1102.0 E(85289): 0
Smith-Waterman score: 8692; 99.9% identity (99.9% similar) in 1279 aa overlap (1-1279:1-1278)
10 20 30 40 50 60
pF1KSD MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTLTERLREKISRAFYNHGLLCASYPIPIILFTGFCILACCYPLLKLPLPGTGPVEFTTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKDYSPPPVDSDRKQGEPTEQPEWYVGAPVAYVQQIFVKSSVFPWHKNLLAVDVFRSPLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAFQLVEEIRNHVLRDSSGIRSLEELCLQVTDLLPGLRKLRNLLPEHGCLLLSPGNFWQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWERFHADPDIIGTIHQHEPKTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLEN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDG
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_005 CLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPG-QRRDSGVGSGLEAQESWERLSDG
790 800 810 820 830
850 860 870 880 890 900
pF1KSD GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KSD CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQK
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KSD PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDG
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KSD AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDL
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KSD GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVC
1200 1210 1220 1230 1240 1250
1270
pF1KSD NFGSELSLVYVPSVLEKLD
:::::::::::::::::::
XP_005 NFGSELSLVYVPSVLEKLD
1260 1270
>>XP_016861408 (OMIM: 601510) PREDICTED: sterol regulato (1049 aa)
initn: 7120 init1: 7120 opt: 7120 Z-score: 4827.2 bits: 905.1 E(85289): 0
Smith-Waterman score: 7120; 100.0% identity (100.0% similar) in 1049 aa overlap (231-1279:1-1049)
210 220 230 240 250 260
pF1KSD KTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHP
::::::::::::::::::::::::::::::
XP_016 MVSYTITLVFQHYHAKFLGSLRARLMLLHP
10 20 30
270 280 290 300 310 320
pF1KSD SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
40 50 60 70 80 90
330 340 350 360 370 380
pF1KSD VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
100 110 120 130 140 150
390 400 410 420 430 440
pF1KSD IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
160 170 180 190 200 210
450 460 470 480 490 500
pF1KSD SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
220 230 240 250 260 270
510 520 530 540 550 560
pF1KSD PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
280 290 300 310 320 330
570 580 590 600 610 620
pF1KSD MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
340 350 360 370 380 390
630 640 650 660 670 680
pF1KSD DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
400 410 420 430 440 450
690 700 710 720 730 740
pF1KSD PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
460 470 480 490 500 510
750 760 770 780 790 800
pF1KSD LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
520 530 540 550 560 570
810 820 830 840 850 860
pF1KSD WDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
580 590 600 610 620 630
870 880 890 900 910 920
pF1KSD PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
640 650 660 670 680 690
930 940 950 960 970 980
pF1KSD QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
700 710 720 730 740 750
990 1000 1010 1020 1030 1040
pF1KSD VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
760 770 780 790 800 810
1050 1060 1070 1080 1090 1100
pF1KSD SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
820 830 840 850 860 870
1110 1120 1130 1140 1150 1160
pF1KSD LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
880 890 900 910 920 930
1170 1180 1190 1200 1210 1220
pF1KSD GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
940 950 960 970 980 990
1230 1240 1250 1260 1270
pF1KSD CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
1000 1010 1020 1030 1040
>>XP_016861409 (OMIM: 601510) PREDICTED: sterol regulato (1048 aa)
initn: 4028 init1: 3975 opt: 7101 Z-score: 4814.4 bits: 902.8 E(85289): 0
Smith-Waterman score: 7101; 99.9% identity (99.9% similar) in 1049 aa overlap (231-1279:1-1048)
210 220 230 240 250 260
pF1KSD KTLQTSATLKDLLFGVPGKYSGVSLYTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHP
::::::::::::::::::::::::::::::
XP_016 MVSYTITLVFQHYHAKFLGSLRARLMLLHP
10 20 30
270 280 290 300 310 320
pF1KSD SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPNCSLRAESLVHVHFKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAV
40 50 60 70 80 90
330 340 350 360 370 380
pF1KSD VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLR
100 110 120 130 140 150
390 400 410 420 430 440
pF1KSD IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVL
160 170 180 190 200 210
450 460 470 480 490 500
pF1KSD SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL
220 230 240 250 260 270
510 520 530 540 550 560
pF1KSD PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAP
280 290 300 310 320 330
570 580 590 600 610 620
pF1KSD MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPE
340 350 360 370 380 390
630 640 650 660 670 680
pF1KSD DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWP
400 410 420 430 440 450
690 700 710 720 730 740
pF1KSD PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQ
460 470 480 490 500 510
750 760 770 780 790 800
pF1KSD LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCV
520 530 540 550 560 570
810 820 830 840 850 860
pF1KSD WDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 WDAQTGDCLTRIPRPG-QRRDSGVGSGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRG
580 590 600 610 620
870 880 890 900 910 920
pF1KSD PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVY
630 640 650 660 670 680
930 940 950 960 970 980
pF1KSD QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLI
690 700 710 720 730 740
990 1000 1010 1020 1030 1040
pF1KSD VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVAARLNGSLDFFSLETHTAL
750 760 770 780 790 800
1050 1060 1070 1080 1090 1100
pF1KSD SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHT
810 820 830 840 850 860
1110 1120 1130 1140 1150 1160
pF1KSD LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHR
870 880 890 900 910 920
1170 1180 1190 1200 1210 1220
pF1KSD GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQG
930 940 950 960 970 980
1230 1240 1250 1260 1270
pF1KSD CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
990 1000 1010 1020 1030 1040
>>XP_005265025 (OMIM: 601510) PREDICTED: sterol regulato (1024 aa)
initn: 6961 init1: 6961 opt: 6961 Z-score: 4719.8 bits: 885.2 E(85289): 0
Smith-Waterman score: 6961; 100.0% identity (100.0% similar) in 1024 aa overlap (256-1279:1-1024)
230 240 250 260 270 280
pF1KSD YTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAEL
::::::::::::::::::::::::::::::
XP_005 MLLHPSPNCSLRAESLVHVHFKEEIGVAEL
10 20 30
290 300 310 320 330 340
pF1KSD IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
40 50 60 70 80 90
350 360 370 380 390 400
pF1KSD GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
100 110 120 130 140 150
410 420 430 440 450 460
pF1KSD GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
160 170 180 190 200 210
470 480 490 500 510 520
pF1KSD KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
220 230 240 250 260 270
530 540 550 560 570 580
pF1KSD VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
280 290 300 310 320 330
590 600 610 620 630 640
pF1KSD KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
340 350 360 370 380 390
650 660 670 680 690 700
pF1KSD KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
400 410 420 430 440 450
710 720 730 740 750 760
pF1KSD VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
460 470 480 490 500 510
770 780 790 800 810 820
pF1KSD EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVG
520 530 540 550 560 570
830 840 850 860 870 880
pF1KSD SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
580 590 600 610 620 630
890 900 910 920 930 940
pF1KSD RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
640 650 660 670 680 690
950 960 970 980 990 1000
pF1KSD PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
700 710 720 730 740 750
1010 1020 1030 1040 1050 1060
pF1KSD VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
760 770 780 790 800 810
1070 1080 1090 1100 1110 1120
pF1KSD VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
820 830 840 850 860 870
1130 1140 1150 1160 1170 1180
pF1KSD YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
880 890 900 910 920 930
1190 1200 1210 1220 1230 1240
pF1KSD DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
940 950 960 970 980 990
1250 1260 1270
pF1KSD PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
::::::::::::::::::::::::::::::::::
XP_005 PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
1000 1010 1020
>>NP_001306973 (OMIM: 601510) sterol regulatory element- (1023 aa)
initn: 3869 init1: 3816 opt: 6942 Z-score: 4707.0 bits: 882.8 E(85289): 0
Smith-Waterman score: 6942; 99.9% identity (99.9% similar) in 1024 aa overlap (256-1279:1-1023)
230 240 250 260 270 280
pF1KSD YTRKRMVSYTITLVFQHYHAKFLGSLRARLMLLHPSPNCSLRAESLVHVHFKEEIGVAEL
::::::::::::::::::::::::::::::
NP_001 MLLHPSPNCSLRAESLVHVHFKEEIGVAEL
10 20 30
290 300 310 320 330 340
pF1KSD IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNG
40 50 60 70 80 90
350 360 370 380 390 400
pF1KSD GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILI
100 110 120 130 140 150
410 420 430 440 450 460
pF1KSD GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSA
160 170 180 190 200 210
470 480 490 500 510 520
pF1KSD KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTV
220 230 240 250 260 270
530 540 550 560 570 580
pF1KSD VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWIGILVYTDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAP
280 290 300 310 320 330
590 600 610 620 630 640
pF1KSD KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLPENQTSPGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLA
340 350 360 370 380 390
650 660 670 680 690 700
pF1KSD KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRYISLLPVIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGD
400 410 420 430 440 450
710 720 730 740 750 760
pF1KSD VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLYKVAALGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPET
460 470 480 490 500 510
770 780 790 800 810 820
pF1KSD EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVG
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_001 EIVPLVLRGHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPG-QRRDSGVG
520 530 540 550 560
830 840 850 860 870 880
pF1KSD SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGLEAQESWERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQP
570 580 590 600 610 620
890 900 910 920 930 940
pF1KSD RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSQPTQPEPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQA
630 640 650 660 670 680
950 960 970 980 990 1000
pF1KSD PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEDEGGSPEKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEE
690 700 710 720 730 740
1010 1020 1030 1040 1050 1060
pF1KSD VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSGITALVFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDT
750 760 770 780 790 800
1070 1080 1090 1100 1110 1120
pF1KSD VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VACHLTHTVPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTV
810 820 830 840 850 860
1130 1140 1150 1160 1170 1180
pF1KSD YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIDQTMVLASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIW
870 880 890 900 910 920
1190 1200 1210 1220 1230 1240
pF1KSD DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRSTGIKFYSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQ
930 940 950 960 970 980
1250 1260 1270
pF1KSD PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
::::::::::::::::::::::::::::::::::
NP_001 PARQILVLDNAAIVCNFGSELSLVYVPSVLEKLD
990 1000 1010 1020
>>XP_011531804 (OMIM: 601510) PREDICTED: sterol regulato (898 aa)
initn: 6163 init1: 6163 opt: 6163 Z-score: 4180.7 bits: 785.3 E(85289): 0
Smith-Waterman score: 6163; 100.0% identity (100.0% similar) in 896 aa overlap (384-1279:3-898)
360 370 380 390 400 410
pF1KSD VVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPA
::::::::::::::::::::::::::::::
XP_011 MAGLSSESWSIMKNMATELGIILIGYFTLVPA
10 20 30
420 430 440 450 460 470
pF1KSD IQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTR
40 50 60 70 80 90
480 490 500 510 520 530
pF1KSD YERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YERQLAVRPSTPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVY
100 110 120 130 140 150
540 550 560 570 580 590
pF1KSD TDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPAGLRNYLAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTS
160 170 180 190 200 210
600 610 620 630 640 650
pF1KSD PGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGESPERGGPAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLP
220 230 240 250 260 270
660 670 680 690 700 710
pF1KSD VIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIPVTLRLNPREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAA
280 290 300 310 320 330
720 730 740 750 760 770
pF1KSD LGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLATGIVLVLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLR
340 350 360 370 380 390
780 790 800 810 820 830
pF1KSD GHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHLMDIECLASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQES
400 410 420 430 440 450
840 850 860 870 880 890
pF1KSD WERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WERLSDGGKAGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQP
460 470 480 490 500 510
900 910 920 930 940 950
pF1KSD EPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPRHRAVCGRSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSP
520 530 540 550 560 570
960 970 980 990 1000 1010
pF1KSD EKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKGSPSLAWAPSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITAL
580 590 600 610 620 630
1020 1030 1040 1050 1060 1070
pF1KSD VFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFLDKRIVAARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHT
640 650 660 670 680 690
1080 1090 1100 1110 1120 1130
pF1KSD VPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPCAHQKPITALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVL
700 710 720 730 740 750
1140 1150 1160 1170 1180 1190
pF1KSD ASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGGQDGAICLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKF
760 770 780 790 800 810
1200 1210 1220 1230 1240 1250
pF1KSD YSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSIQQDLGCGASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVL
820 830 840 850 860 870
1260 1270
pF1KSD DNAAIVCNFGSELSLVYVPSVLEKLD
::::::::::::::::::::::::::
XP_011 DNAAIVCNFGSELSLVYVPSVLEKLD
880 890
>>XP_005265028 (OMIM: 601510) PREDICTED: sterol regulato (887 aa)
initn: 6104 init1: 6104 opt: 6104 Z-score: 4140.8 bits: 777.9 E(85289): 0
Smith-Waterman score: 6104; 100.0% identity (100.0% similar) in 887 aa overlap (393-1279:1-887)
370 380 390 400 410 420
pF1KSD VLTKSVVSTPVDLEVKLRIAQGLSSESWSIMKNMATELGIILIGYFTLVPAIQEFCLFAV
::::::::::::::::::::::::::::::
XP_005 MKNMATELGIILIGYFTLVPAIQEFCLFAV
10 20 30
430 440 450 460 470 480
pF1KSD VGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACLPSAKPVGQPTRYERQLAVRP
40 50 60 70 80 90
490 500 510 520 530 540
pF1KSD STPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPHTITLQPSSFRNLRLPKRLRVVYFLARTRLAQRLIMAGTVVWIGILVYTDPAGLRNY
100 110 120 130 140 150
550 560 570 580 590 600
pF1KSD LAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAAQVTEQSPLGEGALAPMPVPSGMLPPSHPDPAFSIFPPDAPKLPENQTSPGESPERGG
160 170 180 190 200 210
610 620 630 640 650 660
pF1KSD PAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAEVVHDSPVPEVTWGPEDEELWRKLSFRHWPTLFSYYNITLAKRYISLLPVIPVTLRLN
220 230 240 250 260 270
670 680 690 700 710 720
pF1KSD PREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PREALEGRHPQDGRSAWPPPGPIPAGHWEAGPKGPGGVQAHGDVTLYKVAALGLATGIVL
280 290 300 310 320 330
730 740 750 760 770 780
pF1KSD VLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLLLLCLYRVLCPRNYGQLGGGPGRRRRGELPCDDYGYAPPETEIVPLVLRGHLMDIECL
340 350 360 370 380 390
790 800 810 820 830 840
pF1KSD ASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASDGMLLVSCCLAGHVCVWDAQTGDCLTRIPRPGRQRRDSGVGSGLEAQESWERLSDGGK
400 410 420 430 440 450
850 860 870 880 890 900
pF1KSD AGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGPEEPGDSPPLRHRPRGPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCG
460 470 480 490 500 510
910 920 930 940 950 960
pF1KSD RSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSRDSPGYDFSCLVQRVYQEEGLAAVCTPALRPPSPGPVLSQAPEDEGGSPEKGSPSLAW
520 530 540 550 560 570
970 980 990 1000 1010 1020
pF1KSD APSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APSAEGSIWSLELQGNLIVVGRSSGRLEVWDAIEGVLCCSSEEVSSGITALVFLDKRIVA
580 590 600 610 620 630
1030 1040 1050 1060 1070 1080
pF1KSD ARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARLNGSLDFFSLETHTALSPLQFRGTPGRGSSPASPVYSSSDTVACHLTHTVPCAHQKPI
640 650 660 670 680 690
1090 1100 1110 1120 1130 1140
pF1KSD TALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALKAAAGRLVTGSQDHTLRVFRLEDSCCLFTLQGHSGAITTVYIDQTMVLASGGQDGAI
700 710 720 730 740 750
1150 1160 1170 1180 1190 1200
pF1KSD CLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLWDVLTGSRVSHVFAHRGDVTSLTCTTSCVISSGLDDLISIWDRSTGIKFYSIQQDLGC
760 770 780 790 800 810
1210 1220 1230 1240 1250 1260
pF1KSD GASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF
820 830 840 850 860 870
1270
pF1KSD GSELSLVYVPSVLEKLD
:::::::::::::::::
XP_005 GSELSLVYVPSVLEKLD
880
1279 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:36:24 2016 done: Thu Nov 3 00:36:26 2016
Total Scan time: 15.080 Total Display time: 0.470
Function used was FASTA [36.3.4 Apr, 2011]