FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0200, 1016 aa 1>>>pF1KSDA0200 1016 - 1016 aa - 1016 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.9068+/-0.00103; mu= -6.7377+/- 0.062 mean_var=388.0388+/-79.087, 0's: 0 Z-trim(115.2): 48 B-trim: 0 in 0/55 Lambda= 0.065108 statistics sampled from 15716 (15757) to 15716 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.484), width: 16 Scan time: 4.960 The best scores are: opt bits E(32554) CCDS34315.1 MAML1 gene_id:9794|Hs108|chr5 (1016) 6904 663.2 7.4e-190 CCDS54805.1 MAML3 gene_id:55534|Hs108|chr4 (1138) 1021 110.7 1.8e-23 >>CCDS34315.1 MAML1 gene_id:9794|Hs108|chr5 (1016 aa) initn: 6904 init1: 6904 opt: 6904 Z-score: 3522.0 bits: 663.2 E(32554): 7.4e-190 Smith-Waterman score: 6904; 100.0% identity (100.0% similar) in 1016 aa overlap (1-1016:1-1016) 10 20 30 40 50 60 pF1KSD MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA 910 920 930 940 950 960 970 980 990 1000 1010 pF1KSD YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ 970 980 990 1000 1010 >>CCDS54805.1 MAML3 gene_id:55534|Hs108|chr4 (1138 aa) initn: 882 init1: 366 opt: 1021 Z-score: 534.9 bits: 110.7 E(32554): 1.8e-23 Smith-Waterman score: 1797; 35.8% identity (63.4% similar) in 1075 aa overlap (12-981:66-1104) 10 20 30 40 pF1KSD MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARY :.:.::.:.::::.::: ::::: .:: :: CCDS54 TPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRY 40 50 60 70 80 90 50 60 70 80 90 100 pF1KSD EAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHG . .. :.:::::. : .:.:: .. .::..: .. :. : .::.. ... CCDS54 QQAQVEQLELERRDTVSLYQRTLEQRAKKSGAG----TGKQQHPSKPQQDAEAASAEQRN 100 110 120 130 140 150 110 120 130 140 150 pF1KSD RPATHLHDTVKRNLDSATSPQNGDQQNGY--GDLFPGHKKTRREAPLGV-AI----SSNG . :..::::.:..: :: ::::::: :.. : :. :.. :. :: :. CCDS54 HTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMP 160 170 180 190 200 210 160 170 180 190 200 210 pF1KSD LPPASPLGQSD-KPSGADALQSSGKHSLGL-DSLNKK-RLADSSLHLNGGSNPSESFPLS :: :::: : : ::: ::.:: :. :: ..:.:. :: . .: .:: :. .:: . CCDS54 LPSASPLHQLDLKPSL--PLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTIL 220 230 240 250 260 220 230 240 250 260 270 pF1KSD LNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLF .:.:::::..: :. :. .. .:..:. :.:::.:::.:::.:: .::..:..::: CCDS54 QSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLF 270 280 290 300 310 320 280 290 300 310 320 330 pF1KSD NEDFEEKKDPESSGSATQTPLAQD-INIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPS ::::::::.:: : ::.:::.:. ..:.. : . : . ..::::.: .:.: : : CCDS54 NEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPF---S 330 340 350 360 370 380 340 350 360 370 380 pF1KSD SAPVSTDSPSLGGSQTLFHTSGQPR---ADNP-SPNLMPASAQAQNAQRALAGVVL-PS- .. ..:. ::.... . . ...: ...: .:: : . .: : : .: :. CCDS54 TVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPN--QAHTPGQAPPRPGNGYLLNPAA 390 400 410 420 430 440 390 400 410 pF1KSD -------QGPGG--ASELSSAHQLQQIAAKQKR-------------------EQMLQNPQ .:: . .:..: :.::.:.::.:.. .:. :. : CCDS54 VTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ 450 460 470 480 490 500 420 430 440 450 460 470 pF1KSD QATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPR : .: :.:. :: : . . ::: :: : : :.:.. .. : .:. . CCDS54 QQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKT 510 520 530 540 550 560 480 490 500 510 520 530 pF1KSD PGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQ--GSPGSGQ . :: .:.:....:: .::. :: :.: ..: :::::::.:..:: .: : .. CCDS54 TMNNYLPQNHMNMINQQP-NNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANP 570 580 590 600 610 620 540 550 560 pF1KSD SKPALMAYLPQQL------------------------SHISHEQNSLFLMKPKP-GNMP- .: :: :. :: .:.:..:. :.::: : :.: CCDS54 NKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPM 630 640 650 660 670 680 570 580 590 600 610 620 pF1KSD -FRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVS--VASSHNSSP-YLSSQQQAAVMKQH . .: ::::.: ..: .. . .. ::. . :... ..: .:.:: :::.:: CCDS54 AYAALPSHGQEQHPVGLP-RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMK-- 690 700 710 720 730 740 630 640 650 660 670 680 pF1KSD QLLLDQQKQREQQQKHL----QQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGS :.:.::. : .:::. :.:: :.::..::::. : : :: : :. .: .. CCDS54 QMLIDQRAQLIEQQKQQFLREQRQQQQQQQQQILAEQQLQ--QSHL---PRQHLQPQRNP 750 760 770 780 790 690 700 710 720 730 pF1KSD FP-QQVGQFTGSS---AAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSG .: :::.:: :: ::: .. .: .: :.. : ...: .::.. . ... : .. CCDS54 YPVQQVNQFQGSPQDIAAVRSQAALQSMRTS--RLMAQNAGMMGIGPSQ-NPGTMATAAA 800 810 820 830 840 850 740 750 760 770 780 790 pF1KSD QQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQA----TNGHAHIPRQTNVGQNTS :.. :.: . .. : ..:.:..:.::.. : : :. :...:. ::: ::... CCDS54 QSEMGLAPY-STTPTSQPGMYNMSTGMTQML-QHPNQSGMSITHNQAQGPRQPASGQGVG 860 870 880 890 900 910 800 810 820 830 840 pF1KSD VSAAYGQNSLGSSGLSQQHN--KGTLNPGLTKPPVP-RVSPAMGG--QNS-SWQHQGMPN . ...::. : .:...::: :: .. .: .: .: :.. :: :.. :::.... . CCDS54 MVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQG 920 930 940 950 960 970 850 860 870 880 890 900 pF1KSD LSGQTPGNSNVSPFTAASSFHMQQ-QAHL-KMSSPQ-FSQAV--PNRPMAPMSSAAAVG- . :.: : ...::. ..:. .: : .: :. :: .::.: : . . ::.: CCDS54 MPGRTSG--ELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGR 980 990 1000 1010 1020 910 920 930 940 950 pF1KSD SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQM---GGRAGLHC ...: . .:: :: : . ::: . : . :::: ::.:. :. : CCDS54 QMMPSLPGQQGTSQARPMV--------MSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQ 1030 1040 1050 1060 1070 1080 960 970 980 990 1000 1010 pF1KSD TQAYPVRTAGQELPFAYSGQ-PGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ .::: :.: :.. . :::. ::: CCDS54 SQAYE-RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP 1090 1100 1110 1120 1130 1016 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:37:07 2016 done: Thu Nov 3 00:37:08 2016 Total Scan time: 4.960 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]