FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0201, 858 aa 1>>>pF1KSDA0201 858 - 858 aa - 858 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7619+/-0.000496; mu= 4.1892+/- 0.031 mean_var=162.2545+/-32.453, 0's: 0 Z-trim(113.3): 43 B-trim: 1194 in 1/53 Lambda= 0.100688 statistics sampled from 22612 (22647) to 22612 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.266), width: 16 Scan time: 12.780 The best scores are: opt bits E(85289) NP_006635 (OMIM: 610703) heat shock protein 105 kD ( 858) 5657 834.8 0 XP_016875850 (OMIM: 610703) PREDICTED: heat shock ( 851) 5552 819.5 0 NP_001273433 (OMIM: 610703) heat shock protein 105 ( 860) 5420 800.3 0 XP_011533189 (OMIM: 610703) PREDICTED: heat shock ( 853) 5315 785.1 0 XP_011533190 (OMIM: 610703) PREDICTED: heat shock ( 780) 4227 627.0 1e-178 NP_001273434 (OMIM: 610703) heat shock protein 105 ( 782) 4227 627.0 1e-178 XP_016875852 (OMIM: 610703) PREDICTED: heat shock ( 807) 3466 516.5 2e-145 NP_001273432 (OMIM: 610703) heat shock protein 105 ( 814) 3466 516.5 2e-145 XP_016875851 (OMIM: 610703) PREDICTED: heat shock ( 809) 3229 482.1 4.5e-135 XP_005266293 (OMIM: 610703) PREDICTED: heat shock ( 816) 3229 482.1 4.6e-135 NP_002145 (OMIM: 601113) heat shock 70 kDa protein ( 840) 2545 382.7 3.8e-105 XP_016875853 (OMIM: 610703) PREDICTED: heat shock ( 736) 2036 308.8 6.1e-83 NP_005336 (OMIM: 140550) heat shock 70 kDa protein ( 641) 941 149.7 4.1e-35 NP_005337 (OMIM: 603012) heat shock 70 kDa protein ( 641) 941 149.7 4.1e-35 NP_005518 (OMIM: 140559) heat shock 70 kDa protein ( 641) 933 148.5 9.2e-35 XP_011541100 (OMIM: 600816) PREDICTED: heat shock ( 646) 923 147.1 2.5e-34 NP_006588 (OMIM: 600816) heat shock cognate 71 kDa ( 646) 923 147.1 2.5e-34 NP_002146 (OMIM: 140555) heat shock 70 kDa protein ( 643) 920 146.6 3.4e-34 NP_068814 (OMIM: 140560) heat shock-related 70 kDa ( 639) 897 143.3 3.5e-33 NP_005338 (OMIM: 138120) 78 kDa glucose-regulated ( 654) 882 141.1 1.6e-32 NP_694881 (OMIM: 600816) heat shock cognate 71 kDa ( 493) 875 140.0 2.5e-32 NP_004125 (OMIM: 182170,600548,616854) stress-70 p ( 679) 789 127.6 1.9e-28 NP_057383 (OMIM: 610369) heat shock 70 kDa protein ( 509) 670 110.3 2.4e-23 XP_016872586 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 410 72.6 1e-11 XP_016872585 (OMIM: 601746) PREDICTED: hypoxia up- ( 999) 410 72.6 1e-11 NP_001124463 (OMIM: 601746) hypoxia up-regulated p ( 999) 410 72.6 1e-11 NP_006380 (OMIM: 601746) hypoxia up-regulated prot ( 999) 410 72.6 1e-11 XP_005271449 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 410 72.6 1e-11 XP_005271450 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 410 72.6 1e-11 XP_016872584 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 410 72.6 1e-11 XP_005271451 (OMIM: 601746) PREDICTED: hypoxia up- (1000) 410 72.6 1e-11 NP_008879 (OMIM: 601100) heat shock 70 kDa protein ( 471) 229 46.2 0.00043 >>NP_006635 (OMIM: 610703) heat shock protein 105 kDa is (858 aa) initn: 5657 init1: 5657 opt: 5657 Z-score: 4451.7 bits: 834.8 E(85289): 0 Smith-Waterman score: 5657; 100.0% identity (100.0% similar) in 858 aa overlap (1-858:1-858) 10 20 30 40 50 60 pF1KSD MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH 790 800 810 820 830 840 850 pF1KSD QNGECYPNEKNSVNMDLD :::::::::::::::::: NP_006 QNGECYPNEKNSVNMDLD 850 >>XP_016875850 (OMIM: 610703) PREDICTED: heat shock prot (851 aa) initn: 5552 init1: 5552 opt: 5552 Z-score: 4369.3 bits: 819.5 E(85289): 0 Smith-Waterman score: 5552; 99.8% identity (99.8% similar) in 845 aa overlap (1-845:1-845) 10 20 30 40 50 60 pF1KSD MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH 790 800 810 820 830 840 850 pF1KSD QNGECYPNEKNSVNMDLD :: : XP_016 QNDSCGIVNSY 850 >>NP_001273433 (OMIM: 610703) heat shock protein 105 kDa (860 aa) initn: 5420 init1: 5420 opt: 5420 Z-score: 4265.6 bits: 800.3 E(85289): 0 Smith-Waterman score: 5420; 100.0% identity (100.0% similar) in 822 aa overlap (37-858:39-860) 10 20 30 40 50 60 pF1KSD DVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSN :::::::::::::::::::::::::::::: NP_001 GPAAHWVESFQKAREEGSGSGTWRGRWRRRSVISFGSKNRTIGVAAKNQQITHANNTVSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY 790 800 810 820 830 840 850 pF1KSD PNEKNSVNMDLD :::::::::::: NP_001 PNEKNSVNMDLD 850 860 >>XP_011533189 (OMIM: 610703) PREDICTED: heat shock prot (853 aa) initn: 5315 init1: 5315 opt: 5315 Z-score: 4183.2 bits: 785.1 E(85289): 0 Smith-Waterman score: 5315; 99.8% identity (99.8% similar) in 809 aa overlap (37-845:39-847) 10 20 30 40 50 60 pF1KSD DVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSN :::::::::::::::::::::::::::::: XP_011 GPAAHWVESFQKAREEGSGSGTWRGRWRRRSVISFGSKNRTIGVAAKNQQITHANNTVSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNDSCG 790 800 810 820 830 840 850 pF1KSD PNEKNSVNMDLD XP_011 IVNSY 850 >>XP_011533190 (OMIM: 610703) PREDICTED: heat shock prot (780 aa) initn: 4227 init1: 4227 opt: 4227 Z-score: 3329.7 bits: 627.0 E(85289): 1e-178 Smith-Waterman score: 4979; 90.9% identity (90.9% similar) in 858 aa overlap (1-858:1-780) 10 20 30 40 50 60 pF1KSD MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN :::::::::::::::::::::::: XP_011 LLTKLKETAENSLKKPVTDCVISV------------------------------------ 130 140 190 200 210 220 230 240 pF1KSD YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL :::::::::::::::::: XP_011 ------------------------------------------LGTAFDPFLGGKNFDEKL 150 160 250 260 270 280 290 300 pF1KSD VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 170 180 190 200 210 220 310 320 330 340 350 360 pF1KSD MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 230 240 250 260 270 280 370 380 390 400 410 420 pF1KSD DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 290 300 310 320 330 340 430 440 450 460 470 480 pF1KSD SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 350 360 370 380 390 400 490 500 510 520 530 540 pF1KSD KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 410 420 430 440 450 460 550 560 570 580 590 600 pF1KSD QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 470 480 490 500 510 520 610 620 630 640 650 660 pF1KSD NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 530 540 550 560 570 580 670 680 690 700 710 720 pF1KSD DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 590 600 610 620 630 640 730 740 750 760 770 780 pF1KSD QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 650 660 670 680 690 700 790 800 810 820 830 840 pF1KSD RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH 710 720 730 740 750 760 850 pF1KSD QNGECYPNEKNSVNMDLD :::::::::::::::::: XP_011 QNGECYPNEKNSVNMDLD 770 780 >>NP_001273434 (OMIM: 610703) heat shock protein 105 kDa (782 aa) initn: 4227 init1: 4227 opt: 4227 Z-score: 3329.7 bits: 627.0 E(85289): 1e-178 Smith-Waterman score: 4742; 90.5% identity (90.5% similar) in 822 aa overlap (37-858:39-782) 10 20 30 40 50 60 pF1KSD DVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSN :::::::::::::::::::::::::::::: NP_001 GPAAHWVESFQKAREEGSGSGTWRGRWRRRSVISFGSKNRTIGVAAKNQQITHANNTVSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ :::::::::::::::::: NP_001 ETAENSLKKPVTDCVISV------------------------------------------ 130 140 190 200 210 220 230 240 pF1KSD DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA :::::::::::::::::::::::: NP_001 ------------------------------------LGTAFDPFLGGKNFDEKLVEHFCA 150 160 170 250 260 270 280 290 300 pF1KSD EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF 180 190 200 210 220 230 310 320 330 340 350 360 pF1KSD EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL 240 250 260 270 280 290 370 380 390 400 410 420 pF1KSD NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA 300 310 320 330 340 350 430 440 450 460 470 480 pF1KSD PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT 360 370 380 390 400 410 490 500 510 520 530 540 pF1KSD HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT 420 430 440 450 460 470 550 560 570 580 590 600 pF1KSD DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL 480 490 500 510 520 530 610 620 630 640 650 660 pF1KSD GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL 540 550 560 570 580 590 670 680 690 700 710 720 pF1KSD RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY 600 610 620 630 640 650 730 740 750 760 770 780 pF1KSD AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK 660 670 680 690 700 710 790 800 810 820 830 840 pF1KSD TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY 720 730 740 750 760 770 850 pF1KSD PNEKNSVNMDLD :::::::::::: NP_001 PNEKNSVNMDLD 780 >>XP_016875852 (OMIM: 610703) PREDICTED: heat shock prot (807 aa) initn: 5256 init1: 3454 opt: 3466 Z-score: 2732.0 bits: 516.5 E(85289): 2e-145 Smith-Waterman score: 5165; 94.6% identity (94.6% similar) in 845 aa overlap (1-845:1-801) 10 20 30 40 50 60 pF1KSD MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTD------------ 490 500 510 520 550 560 570 580 590 600 pF1KSD QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA :::::::::::::::::::::::::::: XP_016 --------------------------------ANEKKVDQPPEAKKPKIKVVNVELPIEA 530 540 550 610 620 630 640 650 660 pF1KSD NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 560 570 580 590 600 610 670 680 690 700 710 720 pF1KSD DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 620 630 640 650 660 670 730 740 750 760 770 780 pF1KSD QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 680 690 700 710 720 730 790 800 810 820 830 840 pF1KSD RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH 740 750 760 770 780 790 850 pF1KSD QNGECYPNEKNSVNMDLD :: : XP_016 QNDSCGIVNSY 800 >>NP_001273432 (OMIM: 610703) heat shock protein 105 kDa (814 aa) initn: 3454 init1: 3454 opt: 3466 Z-score: 2732.0 bits: 516.5 E(85289): 2e-145 Smith-Waterman score: 5270; 94.9% identity (94.9% similar) in 858 aa overlap (1-858:1-814) 10 20 30 40 50 60 pF1KSD MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTD------------ 490 500 510 520 550 560 570 580 590 600 pF1KSD QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA :::::::::::::::::::::::::::: NP_001 --------------------------------ANEKKVDQPPEAKKPKIKVVNVELPIEA 530 540 550 610 620 630 640 650 660 pF1KSD NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 560 570 580 590 600 610 670 680 690 700 710 720 pF1KSD DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 620 630 640 650 660 670 730 740 750 760 770 780 pF1KSD QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 680 690 700 710 720 730 790 800 810 820 830 840 pF1KSD RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH 740 750 760 770 780 790 850 pF1KSD QNGECYPNEKNSVNMDLD :::::::::::::::::: NP_001 QNGECYPNEKNSVNMDLD 800 810 >>XP_016875851 (OMIM: 610703) PREDICTED: heat shock prot (809 aa) initn: 5019 init1: 3217 opt: 3229 Z-score: 2545.9 bits: 482.1 E(85289): 4.5e-135 Smith-Waterman score: 4928; 94.3% identity (94.3% similar) in 809 aa overlap (37-845:39-803) 10 20 30 40 50 60 pF1KSD DVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSN :::::::::::::::::::::::::::::: XP_016 GPAAHWVESFQKAREEGSGSGTWRGRWRRRSVISFGSKNRTIGVAAKNQQITHANNTVSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT :::::::::::::::::::::::::::::::::::::::::: XP_016 HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTD------------------ 490 500 510 520 530 550 560 570 580 590 600 pF1KSD DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL :::::::::::::::::::::::::::::::::: XP_016 --------------------------ANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL 540 550 560 610 620 630 640 650 660 pF1KSD GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL 570 580 590 600 610 620 670 680 690 700 710 720 pF1KSD RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY 630 640 650 660 670 680 730 740 750 760 770 780 pF1KSD AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK 690 700 710 720 730 740 790 800 810 820 830 840 pF1KSD TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNDSCG 750 760 770 780 790 800 850 pF1KSD PNEKNSVNMDLD XP_016 IVNSY >>XP_005266293 (OMIM: 610703) PREDICTED: heat shock prot (816 aa) initn: 3217 init1: 3217 opt: 3229 Z-score: 2545.9 bits: 482.1 E(85289): 4.6e-135 Smith-Waterman score: 5033; 94.6% identity (94.6% similar) in 822 aa overlap (37-858:39-816) 10 20 30 40 50 60 pF1KSD DVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSN :::::::::::::::::::::::::::::: XP_005 GPAAHWVESFQKAREEGSGSGTWRGRWRRRSVISFGSKNRTIGVAAKNQQITHANNTVSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQT :::::::::::::::::::::::::::::::::::::::::: XP_005 HGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTD------------------ 490 500 510 520 530 550 560 570 580 590 600 pF1KSD DAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL :::::::::::::::::::::::::::::::::: XP_005 --------------------------ANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQL 540 550 560 610 620 630 640 650 660 pF1KSD GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFL 570 580 590 600 610 620 670 680 690 700 710 720 pF1KSD RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHY 630 640 650 660 670 680 730 740 750 760 770 780 pF1KSD AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK 690 700 710 720 730 740 790 800 810 820 830 840 pF1KSD TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECY 750 760 770 780 790 800 850 pF1KSD PNEKNSVNMDLD :::::::::::: XP_005 PNEKNSVNMDLD 810 858 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:37:52 2016 done: Thu Nov 3 00:37:54 2016 Total Scan time: 12.780 Total Display time: 0.270 Function used was FASTA [36.3.4 Apr, 2011]