FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0202, 429 aa 1>>>pF1KSDA0202 429 - 429 aa - 429 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0686+/-0.000574; mu= -4.5056+/- 0.035 mean_var=270.9594+/-56.893, 0's: 0 Z-trim(115.3): 168 B-trim: 1475 in 2/53 Lambda= 0.077915 statistics sampled from 25459 (25629) to 25459 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.3), width: 16 Scan time: 8.440 The best scores are: opt bits E(85289) NP_055961 (OMIM: 608418) septin-8 isoform b [Homo ( 429) 2787 327.0 5.8e-89 NP_001092281 (OMIM: 608418) septin-8 isoform a [Ho ( 483) 2787 327.0 6.4e-89 NP_001092282 (OMIM: 608418) septin-8 isoform c [Ho ( 442) 2780 326.2 1e-88 XP_005271984 (OMIM: 608418) PREDICTED: septin-8 is ( 482) 2780 326.2 1.1e-88 NP_001287728 (OMIM: 608418) septin-8 isoform f [Ho ( 427) 2760 323.9 4.7e-88 XP_005271985 (OMIM: 608418) PREDICTED: septin-8 is ( 481) 2760 324.0 5.2e-88 NP_001287727 (OMIM: 608418) septin-8 isoform e [Ho ( 440) 2753 323.2 8.4e-88 XP_016864743 (OMIM: 608418) PREDICTED: septin-8 is ( 480) 2753 323.2 9e-88 NP_001092283 (OMIM: 608418) septin-8 isoform d [Ho ( 369) 2397 283.1 8.1e-76 XP_011541590 (OMIM: 608418) PREDICTED: septin-8 is ( 423) 2397 283.1 9e-76 XP_005271988 (OMIM: 608418) PREDICTED: septin-8 is ( 423) 2397 283.1 9e-76 XP_016864747 (OMIM: 608418) PREDICTED: septin-8 is ( 382) 2390 282.3 1.4e-75 XP_016864744 (OMIM: 608418) PREDICTED: septin-8 is ( 422) 2390 282.4 1.6e-75 XP_016864750 (OMIM: 608418) PREDICTED: septin-8 is ( 367) 2370 280.1 6.6e-75 XP_016864745 (OMIM: 608418) PREDICTED: septin-8 is ( 421) 2370 280.1 7.4e-75 XP_016864746 (OMIM: 608418) PREDICTED: septin-8 is ( 421) 2370 280.1 7.4e-75 XP_016864749 (OMIM: 608418) PREDICTED: septin-8 is ( 380) 2363 279.3 1.2e-74 XP_016864748 (OMIM: 608418) PREDICTED: septin-8 is ( 380) 2363 279.3 1.2e-74 XP_016863893 (OMIM: 612887) PREDICTED: septin-11 i ( 425) 2230 264.4 4.1e-70 NP_060713 (OMIM: 612887) septin-11 isoform 2 [Homo ( 429) 2230 264.4 4.1e-70 XP_016863892 (OMIM: 612887) PREDICTED: septin-11 i ( 429) 2230 264.4 4.1e-70 XP_016863891 (OMIM: 612887) PREDICTED: septin-11 i ( 435) 2229 264.3 4.5e-70 XP_016863889 (OMIM: 612887) PREDICTED: septin-11 i ( 439) 2229 264.3 4.5e-70 XP_016863890 (OMIM: 612887) PREDICTED: septin-11 i ( 439) 2229 264.3 4.5e-70 NP_001293076 (OMIM: 612887) septin-11 isoform 1 [H ( 439) 2229 264.3 4.5e-70 XP_006724813 (OMIM: 300683) PREDICTED: septin-6 is ( 427) 2170 257.6 4.4e-68 NP_665798 (OMIM: 300683) septin-6 isoform A [Homo ( 427) 2170 257.6 4.4e-68 NP_665799 (OMIM: 300683) septin-6 isoform A [Homo ( 427) 2170 257.6 4.4e-68 NP_665801 (OMIM: 300683) septin-6 isoform D [Homo ( 429) 2170 257.6 4.4e-68 XP_006724811 (OMIM: 300683) PREDICTED: septin-6 is ( 431) 2170 257.6 4.4e-68 NP_055944 (OMIM: 300683) septin-6 isoform B [Homo ( 434) 2170 257.6 4.4e-68 XP_011529620 (OMIM: 300683) PREDICTED: septin-6 is ( 469) 2170 257.7 4.7e-68 XP_005262457 (OMIM: 300683) PREDICTED: septin-6 is ( 491) 2170 257.7 4.9e-68 XP_011529619 (OMIM: 300683) PREDICTED: septin-6 is ( 526) 2170 257.7 5.1e-68 NP_848699 (OMIM: 611737) septin-10 isoform 2 [Homo ( 431) 2094 249.1 1.6e-65 NP_001308429 (OMIM: 611737) septin-10 isoform 6 [H ( 427) 2087 248.3 2.8e-65 NP_001308444 (OMIM: 611737) septin-10 isoform 21 [ ( 422) 2085 248.1 3.3e-65 XP_011509001 (OMIM: 611737) PREDICTED: septin-10 i ( 521) 2087 248.4 3.3e-65 NP_001308443 (OMIM: 611737) septin-10 isoform 20 [ ( 439) 2085 248.1 3.4e-65 NP_653311 (OMIM: 611737) septin-10 isoform 1 [Homo ( 454) 2085 248.1 3.4e-65 NP_001308442 (OMIM: 611737) septin-10 isoform 19 [ ( 441) 2078 247.3 5.8e-65 NP_001308441 (OMIM: 611737) septin-10 isoform 18 [ ( 450) 2078 247.3 5.9e-65 XP_006712380 (OMIM: 611737) PREDICTED: septin-10 i ( 488) 2078 247.3 6.3e-65 XP_011509000 (OMIM: 611737) PREDICTED: septin-10 i ( 529) 2078 247.4 6.7e-65 XP_011509005 (OMIM: 611737) PREDICTED: septin-10 i ( 535) 2078 247.4 6.8e-65 NP_001308427 (OMIM: 611737) septin-10 isoform 4 [H ( 544) 2078 247.4 6.9e-65 NP_001308438 (OMIM: 611737) septin-10 isoform 15 [ ( 412) 2066 245.9 1.4e-64 NP_001308430 (OMIM: 611737) septin-10 isoform 7 [H ( 408) 2059 245.1 2.4e-64 XP_011509002 (OMIM: 611737) PREDICTED: septin-10 i ( 502) 2059 245.2 2.8e-64 XP_006714322 (OMIM: 612887) PREDICTED: septin-11 i ( 372) 1972 235.3 2e-61 >>NP_055961 (OMIM: 608418) septin-8 isoform b [Homo sapi (429 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 1718.1 bits: 327.0 E(85289): 5.8e-89 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 370 380 390 400 410 420 pF1KSD LRKDKDKKN ::::::::: NP_055 LRKDKDKKN >>NP_001092281 (OMIM: 608418) septin-8 isoform a [Homo s (483 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 1717.4 bits: 327.0 E(85289): 6.4e-89 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 370 380 390 400 410 420 pF1KSD LRKDKDKKN ::::::::: NP_001 LRKDKDKKNRSDIGAHQPGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWRE 430 440 450 460 470 480 >>NP_001092282 (OMIM: 608418) septin-8 isoform c [Homo s (442 aa) initn: 2780 init1: 2780 opt: 2780 Z-score: 1713.7 bits: 326.2 E(85289): 1e-88 Smith-Waterman score: 2780; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 370 380 390 400 410 420 pF1KSD LRKDKDKKN :::::::: NP_001 LRKDKDKKKASGWSSIYSVTIP 430 440 >>XP_005271984 (OMIM: 608418) PREDICTED: septin-8 isofor (482 aa) initn: 2780 init1: 2780 opt: 2780 Z-score: 1713.2 bits: 326.2 E(85289): 1.1e-88 Smith-Waterman score: 2780; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 370 380 390 400 410 420 pF1KSD LRKDKDKKN :::::::: XP_005 LRKDKDKKKSDIGAHQPGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWREG 430 440 450 460 470 480 >>NP_001287728 (OMIM: 608418) septin-8 isoform f [Homo s (427 aa) initn: 2027 init1: 2027 opt: 2760 Z-score: 1701.8 bits: 323.9 E(85289): 4.7e-88 Smith-Waterman score: 2760; 99.5% identity (99.5% similar) in 429 aa overlap (1-429:1-427) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: NP_001 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDE--RPI 70 80 90 100 110 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 360 370 380 390 400 410 pF1KSD LRKDKDKKN ::::::::: NP_001 LRKDKDKKN 420 >>XP_005271985 (OMIM: 608418) PREDICTED: septin-8 isofor (481 aa) initn: 2027 init1: 2027 opt: 2760 Z-score: 1701.0 bits: 324.0 E(85289): 5.2e-88 Smith-Waterman score: 2760; 99.5% identity (99.5% similar) in 429 aa overlap (1-429:1-427) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_005 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDE--RPI 70 80 90 100 110 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 360 370 380 390 400 410 pF1KSD LRKDKDKKN ::::::::: XP_005 LRKDKDKKNRSDIGAHQPGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWRE 420 430 440 450 460 470 >>NP_001287727 (OMIM: 608418) septin-8 isoform e [Homo s (440 aa) initn: 2020 init1: 2020 opt: 2753 Z-score: 1697.3 bits: 323.2 E(85289): 8.4e-88 Smith-Waterman score: 2753; 99.5% identity (99.5% similar) in 428 aa overlap (1-428:1-426) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: NP_001 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDE--RPI 70 80 90 100 110 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 360 370 380 390 400 410 pF1KSD LRKDKDKKN :::::::: NP_001 LRKDKDKKKASGWSSIYSVTIP 420 430 440 >>XP_016864743 (OMIM: 608418) PREDICTED: septin-8 isofor (480 aa) initn: 2020 init1: 2020 opt: 2753 Z-score: 1696.8 bits: 323.2 E(85289): 9e-88 Smith-Waterman score: 2753; 99.5% identity (99.5% similar) in 428 aa overlap (1-428:1-426) 10 20 30 40 50 60 pF1KSD MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAATDLERFSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPI ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_016 MNTLFNTTFETEEASHHEACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDE--RPI 70 80 90 100 110 130 140 150 160 170 180 pF1KSD VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKERELHEKFEHLKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQSQALHATSQQP 360 370 380 390 400 410 pF1KSD LRKDKDKKN :::::::: XP_016 LRKDKDKKKSDIGAHQPGMSLSSSKVMMTKASVEPLNCSSWWPAIQCCSCLVRDATWREG 420 430 440 450 460 470 >>NP_001092283 (OMIM: 608418) septin-8 isoform d [Homo s (369 aa) initn: 2397 init1: 2397 opt: 2397 Z-score: 1482.1 bits: 283.1 E(85289): 8.1e-76 Smith-Waterman score: 2397; 100.0% identity (100.0% similar) in 369 aa overlap (61-429:1-369) 40 50 60 70 80 90 pF1KSD PDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEACVRLRPQTYDL :::::::::::::::::::::::::::::: NP_001 MNTLFNTTFETEEASHHEACVRLRPQTYDL 10 20 30 100 110 120 130 140 150 pF1KSD QESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRI 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD HVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSN 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD GVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENH 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD CDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKR 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD KEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRE 280 290 300 310 320 330 400 410 420 pF1KSD LEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKN ::::::::::::::::::::::::::::::::::::::: NP_001 LEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKN 340 350 360 >>XP_011541590 (OMIM: 608418) PREDICTED: septin-8 isofor (423 aa) initn: 2397 init1: 2397 opt: 2397 Z-score: 1481.3 bits: 283.1 E(85289): 9e-76 Smith-Waterman score: 2397; 100.0% identity (100.0% similar) in 369 aa overlap (61-429:1-369) 40 50 60 70 80 90 pF1KSD PDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEACVRLRPQTYDL :::::::::::::::::::::::::::::: XP_011 MNTLFNTTFETEEASHHEACVRLRPQTYDL 10 20 30 100 110 120 130 140 150 pF1KSD QESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRI 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD HVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSN 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD GVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENH 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD CDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKR 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD KEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRRE 280 290 300 310 320 330 400 410 420 pF1KSD LEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKN ::::::::::::::::::::::::::::::::::::::: XP_011 LEEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKNRSDIGAHQPGMSLSSSKVMMT 340 350 360 370 380 390 XP_011 KASVEPLNCSSWWPAIQCCSCLVRDATWREGFL 400 410 420 429 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:38:32 2016 done: Thu Nov 3 00:38:34 2016 Total Scan time: 8.440 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]