FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0214, 757 aa 1>>>pF1KSDA0214 757 - 757 aa - 757 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7853+/-0.00113; mu= 13.4924+/- 0.068 mean_var=98.8581+/-19.394, 0's: 0 Z-trim(104.6): 22 B-trim: 9 in 1/52 Lambda= 0.128994 statistics sampled from 7997 (8002) to 7997 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.246), width: 16 Scan time: 3.160 The best scores are: opt bits E(32554) CCDS30587.1 MFN2 gene_id:9927|Hs108|chr1 ( 757) 4977 937.3 0 CCDS3228.1 MFN1 gene_id:55669|Hs108|chr3 ( 741) 3182 603.3 4.6e-172 >>CCDS30587.1 MFN2 gene_id:9927|Hs108|chr1 (757 aa) initn: 4977 init1: 4977 opt: 4977 Z-score: 5007.8 bits: 937.3 E(32554): 0 Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757) 10 20 30 40 50 60 pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK 670 680 690 700 710 720 730 740 750 pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR ::::::::::::::::::::::::::::::::::::: CCDS30 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR 730 740 750 >>CCDS3228.1 MFN1 gene_id:55669|Hs108|chr3 (741 aa) initn: 3150 init1: 2477 opt: 3182 Z-score: 3202.6 bits: 603.3 E(32554): 4.6e-172 Smith-Waterman score: 3182; 63.6% identity (87.8% similar) in 739 aa overlap (21-756:1-736) 10 20 30 40 50 60 pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT ::: .::::::: ::: :..::.:: .. :.. :.: : CCDS32 MAE-PVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEAT 10 20 30 70 80 90 100 110 120 pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK :.: ::: ..::.......:: .:. :.:::.:::::::::::::.:::.::::::::: CCDS32 YKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDK 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS :::::::: ::::: :::::: .:.:.::::.::.:.:::::::::::.::.:.:: :: CCDS32 VLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVR 100 110 120 130 140 150 190 200 210 220 230 240 pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF :.::..:: ::.:::::.:::: :::::::::::::::::::::::::::::::.::::: CCDS32 VFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHF 160 170 180 190 200 210 250 260 270 280 290 300 pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR ::::.::::.:::::::::::::::::::::.::::::::: :::.:: ::. .: .: CCDS32 FHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ ::::::::::.:: ::::::::.: ::::::..:. ::::::. :::::::::::::::: CCDS32 IFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQ 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK ::.::::: .:. ::::...::.... : : ::.. ::: :: .:..::. : : .:: CCDS32 HTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIK 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD ..:::: .:: ::..:: :::::::.. .:::.: :::.::.::..:::.:.:::..: CCDS32 EVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLAD 400 410 420 430 440 450 490 500 510 520 530 540 pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED ::. .. . ::..:..::::::....... :.: . :.:.:.:: :::.::::: CCDS32 RCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIPCKKFDLSYNLNYHKLCSDFQED 460 470 480 490 500 510 550 560 570 580 590 pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYND---QVQRPIPLTPANPSMPPLPQGSLTQE : :.:::::. ::.:::::.:..:.:.: .. :. : . ::. :. : :... .:: CCDS32 IVFRFSLGWSSLVHRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNA-SQE 520 530 540 550 560 570 600 610 620 630 640 650 pF1KSD EFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAK :.:...::::::.::::::::..::::.::..::.:...:. .:: ::.::::.:::.:: CCDS32 ELMITLVTGLASVTSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAK 580 590 600 610 620 630 660 670 680 690 700 710 pF1KSD ERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAM :::::.:::..:.:::....: :..::::::.:... :::.::::::.:...::.::: . CCDS32 ERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARL 640 650 660 670 680 690 720 730 740 750 pF1KSD NKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR :.:. :...:...::::::: :..::. ::.:.: :: CCDS32 PKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFL-PSSNEES 700 710 720 730 740 757 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:43:03 2016 done: Thu Nov 3 00:43:04 2016 Total Scan time: 3.160 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]