FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0214, 757 aa
1>>>pF1KSDA0214 757 - 757 aa - 757 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7853+/-0.00113; mu= 13.4924+/- 0.068
mean_var=98.8581+/-19.394, 0's: 0 Z-trim(104.6): 22 B-trim: 9 in 1/52
Lambda= 0.128994
statistics sampled from 7997 (8002) to 7997 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.246), width: 16
Scan time: 3.160
The best scores are: opt bits E(32554)
CCDS30587.1 MFN2 gene_id:9927|Hs108|chr1 ( 757) 4977 937.3 0
CCDS3228.1 MFN1 gene_id:55669|Hs108|chr3 ( 741) 3182 603.3 4.6e-172
>>CCDS30587.1 MFN2 gene_id:9927|Hs108|chr1 (757 aa)
initn: 4977 init1: 4977 opt: 4977 Z-score: 5007.8 bits: 937.3 E(32554): 0
Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)
10 20 30 40 50 60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
670 680 690 700 710 720
730 740 750
pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
:::::::::::::::::::::::::::::::::::::
CCDS30 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
730 740 750
>>CCDS3228.1 MFN1 gene_id:55669|Hs108|chr3 (741 aa)
initn: 3150 init1: 2477 opt: 3182 Z-score: 3202.6 bits: 603.3 E(32554): 4.6e-172
Smith-Waterman score: 3182; 63.6% identity (87.8% similar) in 739 aa overlap (21-756:1-736)
10 20 30 40 50 60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
::: .::::::: ::: :..::.:: .. :.. :.: :
CCDS32 MAE-PVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEAT
10 20 30
70 80 90 100 110 120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
:.: ::: ..::.......:: .:. :.:::.:::::::::::::.:::.:::::::::
CCDS32 YKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
:::::::: ::::: :::::: .:.:.::::.::.:.:::::::::::.::.:.:: ::
CCDS32 VLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
:.::..:: ::.:::::.:::: :::::::::::::::::::::::::::::::.:::::
CCDS32 VFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHF
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
::::.::::.:::::::::::::::::::::.::::::::: :::.:: ::. .: .:
CCDS32 FHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
::::::::::.:: ::::::::.: ::::::..:. ::::::. ::::::::::::::::
CCDS32 IFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
::.::::: .:. ::::...::.... : : ::.. ::: :: .:..::. : : .::
CCDS32 HTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIK
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
..:::: .:: ::..:: :::::::.. .:::.: :::.::.::..:::.:.:::..:
CCDS32 EVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLAD
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
::. .. . ::..:..::::::....... :.: . :.:.:.:: :::.:::::
CCDS32 RCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIPCKKFDLSYNLNYHKLCSDFQED
460 470 480 490 500 510
550 560 570 580 590
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYND---QVQRPIPLTPANPSMPPLPQGSLTQE
: :.:::::. ::.:::::.:..:.:.: .. :. : . ::. :. : :... .::
CCDS32 IVFRFSLGWSSLVHRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNA-SQE
520 530 540 550 560 570
600 610 620 630 640 650
pF1KSD EFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAK
:.:...::::::.::::::::..::::.::..::.:...:. .:: ::.::::.:::.::
CCDS32 ELMITLVTGLASVTSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAK
580 590 600 610 620 630
660 670 680 690 700 710
pF1KSD ERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAM
:::::.:::..:.:::....: :..::::::.:... :::.::::::.:...::.::: .
CCDS32 ERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARL
640 650 660 670 680 690
720 730 740 750
pF1KSD NKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
:.:. :...:...::::::: :..::. ::.:.: ::
CCDS32 PKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFL-PSSNEES
700 710 720 730 740
757 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:43:03 2016 done: Thu Nov 3 00:43:04 2016
Total Scan time: 3.160 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]