Result of FASTA (omim) for pF1KSDA0214
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0214, 757 aa
  1>>>pF1KSDA0214 757 - 757 aa - 757 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8832+/-0.000446; mu= 13.2785+/- 0.028
 mean_var=109.6996+/-22.530, 0's: 0 Z-trim(112.3): 26  B-trim: 82 in 2/53
 Lambda= 0.122454
 statistics sampled from 21132 (21151) to 21132 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.248), width:  16
 Scan time: 10.250

The best scores are:                                      opt bits E(85289)
XP_005263602 (OMIM: 601152,608507,609260,617087) P ( 757) 4977 890.8       0
XP_005263605 (OMIM: 601152,608507,609260,617087) P ( 757) 4977 890.8       0
XP_005263600 (OMIM: 601152,608507,609260,617087) P ( 757) 4977 890.8       0
NP_001121132 (OMIM: 601152,608507,609260,617087) m ( 757) 4977 890.8       0
XP_005263604 (OMIM: 601152,608507,609260,617087) P ( 757) 4977 890.8       0
NP_055689 (OMIM: 601152,608507,609260,617087) mito ( 757) 4977 890.8       0
XP_005247653 (OMIM: 608506) PREDICTED: mitofusin-1 ( 741) 3182 573.7 9.5e-163
NP_284941 (OMIM: 608506) mitofusin-1 [Homo sapiens ( 741) 3182 573.7 9.5e-163
XP_011511265 (OMIM: 608506) PREDICTED: mitofusin-1 ( 594) 2525 457.6 6.9e-128


>>XP_005263602 (OMIM: 601152,608507,609260,617087) PREDI  (757 aa)
 initn: 4977 init1: 4977 opt: 4977  Z-score: 4756.5  bits: 890.8 E(85289):    0
Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
              670       680       690       700       710       720

              730       740       750       
pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
       :::::::::::::::::::::::::::::::::::::
XP_005 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
              730       740       750       

>>XP_005263605 (OMIM: 601152,608507,609260,617087) PREDI  (757 aa)
 initn: 4977 init1: 4977 opt: 4977  Z-score: 4756.5  bits: 890.8 E(85289):    0
Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
              670       680       690       700       710       720

              730       740       750       
pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
       :::::::::::::::::::::::::::::::::::::
XP_005 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
              730       740       750       

>>XP_005263600 (OMIM: 601152,608507,609260,617087) PREDI  (757 aa)
 initn: 4977 init1: 4977 opt: 4977  Z-score: 4756.5  bits: 890.8 E(85289):    0
Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
              670       680       690       700       710       720

              730       740       750       
pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
       :::::::::::::::::::::::::::::::::::::
XP_005 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
              730       740       750       

>>NP_001121132 (OMIM: 601152,608507,609260,617087) mitof  (757 aa)
 initn: 4977 init1: 4977 opt: 4977  Z-score: 4756.5  bits: 890.8 E(85289):    0
Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
              670       680       690       700       710       720

              730       740       750       
pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
       :::::::::::::::::::::::::::::::::::::
NP_001 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
              730       740       750       

>>XP_005263604 (OMIM: 601152,608507,609260,617087) PREDI  (757 aa)
 initn: 4977 init1: 4977 opt: 4977  Z-score: 4756.5  bits: 890.8 E(85289):    0
Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
              670       680       690       700       710       720

              730       740       750       
pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
       :::::::::::::::::::::::::::::::::::::
XP_005 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
              730       740       750       

>>NP_055689 (OMIM: 601152,608507,609260,617087) mitofusi  (757 aa)
 initn: 4977 init1: 4977 opt: 4977  Z-score: 4756.5  bits: 890.8 E(85289):    0
Smith-Waterman score: 4977; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKK
              670       680       690       700       710       720

              730       740       750       
pF1KSD IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
       :::::::::::::::::::::::::::::::::::::
NP_055 IEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
              730       740       750       

>>XP_005247653 (OMIM: 608506) PREDICTED: mitofusin-1 iso  (741 aa)
 initn: 3150 init1: 2477 opt: 3182  Z-score: 3042.8  bits: 573.7 E(85289): 9.5e-163
Smith-Waterman score: 3182; 63.6% identity (87.8% similar) in 739 aa overlap (21-756:1-736)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
                           :::  .::::::: ::: :..::.::  .. :.. :.: :
XP_005                     MAE-PVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEAT
                                    10        20        30         

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       :.: ::: ..::.......:: .:.  :.:::.:::::::::::::.:::.:::::::::
XP_005 YKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDK
      40        50        60        70        80        90         

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       :::::::: ::::: :::::: .:.:.::::.::.:.:::::::::::.::.:.:: :: 
XP_005 VLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVR
     100       110       120       130       140       150         

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       :.::..:: ::.:::::.:::: :::::::::::::::::::::::::::::::.:::::
XP_005 VFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHF
     160       170       180       190       200       210         

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::.::::.:::::::::::::::::::::.:::::::::  :::.:: ::.  .: .:
XP_005 FHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNR
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::.:: ::::::::.: ::::::..:. ::::::. ::::::::::::::::
XP_005 IFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQ
     280       290       300       310       320       330         

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::.:::::  .:. ::::...::.... :  : ::.. ::: :: .:..::. : : .::
XP_005 HTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIK
     340       350       360       370       380       390         

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ..::::  .:: ::..:: :::::::..  .:::.: :::.::.::..:::.:.:::..:
XP_005 EVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLAD
     400       410       420       430       440       450         

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::.  ..  .   ::..:..::::::.......  :.: . :.:.:.::  :::.:::::
XP_005 RCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIPCKKFDLSYNLNYHKLCSDFQED
     460       470       480       490       500       510         

              550       560       570          580       590       
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYND---QVQRPIPLTPANPSMPPLPQGSLTQE
       : :.:::::. ::.:::::.:..:.:.: ..   :. : .  ::. :. :  :... .::
XP_005 IVFRFSLGWSSLVHRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNA-SQE
     520       530       540       550       560       570         

       600       610       620       630       640       650       
pF1KSD EFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAK
       :.:...::::::.::::::::..::::.::..::.:...:. .:: ::.::::.:::.::
XP_005 ELMITLVTGLASVTSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAK
      580       590       600       610       620       630        

       660       670       680       690       700       710       
pF1KSD ERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAM
       :::::.:::..:.:::....: :..::::::.:... :::.::::::.:...::.::: .
XP_005 ERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARL
      640       650       660       670       680       690        

       720       730       740       750           
pF1KSD NKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR    
        :.:. :...:...:::::::  :..::. ::.:.: ::     
XP_005 PKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFL-PSSNEES
      700       710       720       730        740 

>>NP_284941 (OMIM: 608506) mitofusin-1 [Homo sapiens]     (741 aa)
 initn: 3150 init1: 2477 opt: 3182  Z-score: 3042.8  bits: 573.7 E(85289): 9.5e-163
Smith-Waterman score: 3182; 63.6% identity (87.8% similar) in 739 aa overlap (21-756:1-736)

               10        20        30        40        50        60
pF1KSD MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDT
                           :::  .::::::: ::: :..::.::  .. :.. :.: :
NP_284                     MAE-PVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEAT
                                    10        20        30         

               70        80        90       100       110       120
pF1KSD YRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDK
       :.: ::: ..::.......:: .:.  :.:::.:::::::::::::.:::.:::::::::
NP_284 YKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDK
      40        50        60        70        80        90         

              130       140       150       160       170       180
pF1KSD VLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVS
       :::::::: ::::: :::::: .:.:.::::.::.:.:::::::::::.::.:.:: :: 
NP_284 VLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVR
     100       110       120       130       140       150         

              190       200       210       220       230       240
pF1KSD VMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHF
       :.::..:: ::.:::::.:::: :::::::::::::::::::::::::::::::.:::::
NP_284 VFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHF
     160       170       180       190       200       210         

              250       260       270       280       290       300
pF1KSD FHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDR
       ::::.::::.:::::::::::::::::::::.:::::::::  :::.:: ::.  .: .:
NP_284 FHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNR
     220       230       240       250       260       270         

              310       320       330       340       350       360
pF1KSD IFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQ
       ::::::::::.:: ::::::::.: ::::::..:. ::::::. ::::::::::::::::
NP_284 IFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQ
     280       290       300       310       320       330         

              370       380       390       400       410       420
pF1KSD HTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIK
       ::.:::::  .:. ::::...::.... :  : ::.. ::: :: .:..::. : : .::
NP_284 HTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIK
     340       350       360       370       380       390         

              430       440       450       460       470       480
pF1KSD QITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSD
       ..::::  .:: ::..:: :::::::..  .:::.: :::.::.::..:::.:.:::..:
NP_284 EVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLAD
     400       410       420       430       440       450         

              490       500       510       520       530       540
pF1KSD RCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQED
       ::.  ..  .   ::..:..::::::.......  :.: . :.:.:.::  :::.:::::
NP_284 RCTDEVNALVLQTQQEIIENLKPLLPAGIQDKLHTLIPCKKFDLSYNLNYHKLCSDFQED
     460       470       480       490       500       510         

              550       560       570          580       590       
pF1KSD IEFHFSLGWTMLVNRFLGPKNSRRALMGYND---QVQRPIPLTPANPSMPPLPQGSLTQE
       : :.:::::. ::.:::::.:..:.:.: ..   :. : .  ::. :. :  :... .::
NP_284 IVFRFSLGWSSLVHRFLGPRNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNA-SQE
     520       530       540       550       560       570         

       600       610       620       630       640       650       
pF1KSD EFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAK
       :.:...::::::.::::::::..::::.::..::.:...:. .:: ::.::::.:::.::
NP_284 ELMITLVTGLASVTSRTSMGIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAK
      580       590       600       610       620       630        

       660       670       680       690       700       710       
pF1KSD ERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAM
       :::::.:::..:.:::....: :..::::::.:... :::.::::::.:...::.::: .
NP_284 ERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARL
      640       650       660       670       680       690        

       720       730       740       750           
pF1KSD NKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR    
        :.:. :...:...:::::::  :..::. ::.:.: ::     
NP_284 PKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFL-PSSNEES
      700       710       720       730        740 

>>XP_011511265 (OMIM: 608506) PREDICTED: mitofusin-1 iso  (594 aa)
 initn: 2497 init1: 1824 opt: 2525  Z-score: 2417.0  bits: 457.6 E(85289): 6.9e-128
Smith-Waterman score: 2525; 62.7% identity (87.6% similar) in 590 aa overlap (170-756:2-589)

     140       150       160       170       180       190         
pF1KSD DGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMD
                                     ::.:.:: :: :.::..:: ::.:::::.:
XP_011                              MDKDLKAGCLVRVFWPKAKCALLRDDLVLVD
                                            10        20        30 

     200       210       220       230       240       250         
pF1KSD SPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNR
       ::: :::::::::::::::::::::::::::::::.:::::::::.::::.:::::::::
XP_011 SPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNR
              40        50        60        70        80        90 

     260       270       280       290       300       310         
pF1KSD WDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQG
       ::::::::::::.:::::::::  :::.:: ::.  .: .:::::::::::.:: :::::
XP_011 WDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQG
             100       110       120       130       140       150 

     320       330       340       350       360       370         
pF1KSD MPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSL
       :::.: ::::::..:. ::::::. ::::::::::::::::::.:::::  .:. ::::.
XP_011 MPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSV
             160       170       180       190       200       210 

     380       390       400       410       420       430         
pF1KSD HMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQITEEVERQVSTAMAEEIR
       ..::.... :  : ::.. ::: :: .:..::. : : .::..::::  .:: ::..:: 
XP_011 NLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEIC
             220       230       240       250       260       270 

     440       450       460       470       480       490         
pF1KSD RLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMID
       :::::::..  .:::.: :::.::.::..:::.:.:::..:::.  ..  .   ::..:.
XP_011 RLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQEIIE
             280       290       300       310       320       330 

     500       510       520       530       540       550         
pF1KSD GLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGP
       .::::::.......  :.: . :.:.:.::  :::.:::::: :.:::::. ::.:::::
XP_011 NLKPLLPAGIQDKLHTLIPCKKFDLSYNLNYHKLCSDFQEDIVFRFSLGWSSLVHRFLGP
             340       350       360       370       380       390 

     560       570          580       590       600       610      
pF1KSD KNSRRALMGYND---QVQRPIPLTPANPSMPPLPQGSLTQEEFMVSMVTGLASLTSRTSM
       .:..:.:.: ..   :. : .  ::. :. :  :... .:::.:...::::::.::::::
XP_011 RNAQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNA-SQEELMITLVTGLASVTSRTSM
             400       410       420        430       440       450

        620       630       640       650       660       670      
pF1KSD GILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLV
       ::..::::.::..::.:...:. .:: ::.::::.:::.:::::::.:::..:.:::...
XP_011 GIIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAKERAFKQQFVNYATEKLRMI
              460       470       480       490       500       510

        680       690       700       710       720       730      
pF1KSD ISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKKIEVLDSLQSKAKLLRN
       .: :..::::::.:... :::.::::::.:...::.::: . :.:. :...:...:::::
XP_011 VSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRN
              520       530       540       550       560       570

        740       750           
pF1KSD KAGWLDSELNMFTHQYLQPSR    
       ::  :..::. ::.:.: ::     
XP_011 KAVQLENELENFTKQFL-PSSNEES
              580        590    




757 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 00:43:04 2016 done: Thu Nov  3 00:43:06 2016
 Total Scan time: 10.250 Total Display time:  0.170

Function used was FASTA [36.3.4 Apr, 2011]
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