FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0221, 1129 aa 1>>>pF1KSDA0221 1129 - 1129 aa - 1129 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6919+/-0.00105; mu= 14.4146+/- 0.064 mean_var=196.6459+/-40.157, 0's: 0 Z-trim(111.6): 25 B-trim: 125 in 1/50 Lambda= 0.091460 statistics sampled from 12513 (12533) to 12513 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.385), width: 16 Scan time: 3.620 The best scores are: opt bits E(32554) CCDS74315.1 UPF1 gene_id:5976|Hs108|chr19 (1129) 7595 1015.6 0 CCDS12386.1 UPF1 gene_id:5976|Hs108|chr19 (1118) 5115 688.4 2.5e-197 CCDS3700.2 ZGRF1 gene_id:55345|Hs108|chr4 (2104) 562 87.9 2.7e-16 CCDS8187.1 IGHMBP2 gene_id:3508|Hs108|chr11 ( 993) 496 78.8 6.7e-14 CCDS6947.1 SETX gene_id:23064|Hs108|chr9 (2677) 450 73.2 9.1e-12 >>CCDS74315.1 UPF1 gene_id:5976|Hs108|chr19 (1129 aa) initn: 7595 init1: 7595 opt: 7595 Z-score: 5424.7 bits: 1015.6 E(32554): 0 Smith-Waterman score: 7595; 99.9% identity (100.0% similar) in 1129 aa overlap (1-1129:1-1129) 10 20 30 40 50 60 pF1KSD MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GPGGAGAGSAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPI ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GPGGAGAGAAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 HACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 WLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVII 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD WLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 WLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD QVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD LTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD ADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD VVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD AFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 AFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD AANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 AANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 QGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD NYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 NYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SSQGRPSSMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SSQGRPSSMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD TPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQ 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 pF1KSD PGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY 1090 1100 1110 1120 >>CCDS12386.1 UPF1 gene_id:5976|Hs108|chr19 (1118 aa) initn: 7505 init1: 5103 opt: 5115 Z-score: 3656.2 bits: 688.4 E(32554): 2.5e-197 Smith-Waterman score: 7487; 98.9% identity (99.0% similar) in 1129 aa overlap (1-1129:1-1118) 10 20 30 40 50 60 pF1KSD MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GPGGAGAGSAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPI ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GPGGAGAGAAAGQLDAQVGPEGILQNGAVDDSVAKTSQLLAELNFEEDEEDTYYTKDLPI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD HACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 HACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD WLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 WLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDAY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVII :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDS-------- 310 320 330 340 350 370 380 390 400 410 420 pF1KSD WLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ---DMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHNF 360 370 380 390 400 430 440 450 460 470 480 pF1KSD QVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLP 410 420 430 440 450 460 490 500 510 520 530 540 pF1KSD DLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 470 480 490 500 510 520 550 560 570 580 590 600 pF1KSD LTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSS 530 540 550 560 570 580 610 620 630 640 650 660 pF1KSD ADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVP 590 600 610 620 630 640 670 680 690 700 710 720 pF1KSD VVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALS 650 660 670 680 690 700 730 740 750 760 770 780 pF1KSD AFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTE 710 720 730 740 750 760 790 800 810 820 830 840 pF1KSD AANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAF 770 780 790 800 810 820 850 860 870 880 890 900 pF1KSD QGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLL 830 840 850 860 870 880 910 920 930 940 950 960 pF1KSD NYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 NYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDR 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KSD SSQGRPSSMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SSQGRPSSMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGRG 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KSD TPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMSQ 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 pF1KSD PGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY 1070 1080 1090 1100 1110 >>CCDS3700.2 ZGRF1 gene_id:55345|Hs108|chr4 (2104 aa) initn: 530 init1: 200 opt: 562 Z-score: 406.0 bits: 87.9 E(32554): 2.7e-16 Smith-Waterman score: 702; 32.2% identity (64.6% similar) in 438 aa overlap (483-902:1632-2055) 460 470 480 490 500 510 pF1KSD YHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVLQR--PLSLIQGPPGTGKT .: .. :: . . :...:.: :.::. CCDS37 TLKLASELIQVHKLNKDQATALIQIAQMMASHESIEEVKELQTHTFPITIIHGVFGAGKS 1610 1620 1630 1640 1650 1660 520 530 540 550 pF1KSD VTSATIVY---HLARQGNGP---------VLVCAPSNIAVDQLTEKIHQTGLK-VVRLCA :... .: .....: .:. . .:.:::.. . . :.. .:. CCDS37 YLLAVVILFFVQLFEKSEAPTIGNARPWKLLISSSTNVAVDRVLLGLLSLGFENFIRV-- 1670 1680 1690 1700 1710 560 570 580 590 600 610 pF1KSD KSREAIDSPVSFLALHNQIRNM-DSMPELQKLQQLKDETGELSSADEKRYRALKRTAERE : . : .:. .:: .: ... ::. :.. .: : .: . : ..: CCDS37 GSVRKIAKPILPYSLHAGSENESEQLKELHALMK-EDLTPTERVYVRKSIEQHKLGTNRT 1720 1730 1740 1750 1760 1770 620 630 640 650 660 670 pF1KSD LLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVV-LGAKQLILVGDHC :: .. :. ::.. : . ..: ...:: .: ::: ..:.. . ..:::::: CCDS37 LLKQVRVVGVTCAACPFPCMNDLKFPVVVLDECSQITEPASLLPIARFECEKLILVGDPK 1780 1790 1800 1810 1820 1830 680 690 700 710 720 730 pF1KSD QLGPVVMCKKAA-KAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQN :: :... . :: . :: :.::.:: ..: .:: :..::: :::.::. ...::.:.:.: CCDS37 QLPPTIQGSDAAHENGLEQTLFDRLCLMGHKPILLRTQYRCHPAISAIANDLFYKGALMN 1840 1850 1860 1870 1880 1890 740 750 760 770 780 790 pF1KSD GVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLLKA ::: .: ..: : . :: ..: :.: .. :. : .::. . :. .:. . CCDS37 GVTEIERSPL---LEW-LP--TLCFYNVKGLEQIERDN-SFHNVAEATFTLKLIQSLIAS 1900 1910 1920 1930 1940 1950 800 810 820 830 840 850 pF1KSD GAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVR : ..::.:: :..: : . .. . ..: . :....:::::: ::..::::::: CCDS37 GIAGSMIGVITLYKSQM-YKLCHLLSAVDFHHPDIKTVQVSTVDAFQGAEKEIIILSCVR 1960 1970 1980 1990 2000 2010 860 870 880 890 900 910 pF1KSD ANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVEGPL . . .::... .:.::::::.. ..:::: : :. ::...... CCDS37 TRQ---VGFIDSEKRMNVALTRGKRHLLIVGNLACLRKNQLWGRVIQHCEGREDGLQHAN 2020 2030 2040 2050 2060 920 930 940 950 960 970 pF1KSD NNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSSMYFQTH CCDS37 QYEPQLNHLLKDYFEKQVEEKQKKKSEKEKSKDKSHS 2070 2080 2090 2100 >>CCDS8187.1 IGHMBP2 gene_id:3508|Hs108|chr11 (993 aa) initn: 379 init1: 221 opt: 496 Z-score: 363.0 bits: 78.8 E(32554): 6.7e-14 Smith-Waterman score: 678; 31.0% identity (59.3% similar) in 565 aa overlap (389-906:86-633) 360 370 380 390 400 410 pF1KSD IIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPD--NYGDEIAIEL-----RSSVG : .. . : : :...: . ..:: CCDS81 RTGLYGRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVT 60 70 80 90 100 110 420 430 440 450 460 pF1KSD APVEVTHNFQVDF----------VWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEV . . .:.::... . ..... :...:: .. ... .. . . :.:. . CCDS81 VAFDESHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSA 120 130 140 150 160 170 470 480 490 500 510 520 pF1KSD EDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHL . . . : : : . :: :: .: :. :..:.::::::::.: . :. . CCDS81 PSPASEIH-PLTFFNTCL---DTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQA 180 190 200 210 220 230 530 540 550 560 570 pF1KSD ARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSR--EAID--SPVSFLALHN-- ..:: :: :::::::::.:.:.. ...:: .: :.:. : . :: . CCDS81 VKQGL-KVLCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSA 240 250 260 270 280 290 580 590 600 610 620 pF1KSD QI-----RNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAER---ELLMNADVICC :: ...:.. .: : : : ... . . . ::. : : : .:.:. CCDS81 QIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLA 300 310 320 330 340 350 630 640 650 660 670 680 pF1KSD TCVGAG--DPR--LAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVM : .::. : : . : ..::: .:: : : .:. : :.. ::.::: :: :... CCDS81 TNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPL-LKARKCILAGDHKQLPPTTV 360 370 380 390 400 690 700 710 720 730 740 pF1KSD CKKAAKAGLSQSLFERLVV-LGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVTAAD .::: :::: ::.:::. : : .: : :::::: :. . :. .: :.: ..: CCDS81 SHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVAR 410 420 430 440 450 460 750 760 770 780 790 pF1KSD RVKKGFD--FQWPQPDKPMFFYVTQG-------QEEIASSGTSYLNRTEAANVEKITTKL .. . . . :... : : .:. :.:. : . ... : CCDS81 HLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQA----L 470 480 490 500 510 520 800 810 820 830 840 850 pF1KSD LKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILS . ::. .:....::. : . : : . .: . :.:: :::.::::::. .::: CCDS81 VDAGVPARDIAVVSPYNLQVDLLRQSL-----VHR--HPELEIKSVDGFQGREKEAVILS 530 540 550 560 570 860 870 880 890 900 910 pF1KSD CVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVE ::.:.. .::: . ::.:::.:::: : .. . ...... . . :..:. .. CCDS81 FVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRT 580 590 600 610 620 630 920 930 940 950 960 970 pF1KSD GPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSSMYF CCDS81 AFEYLDDIVPENYSHENSQGSSHAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPA 640 650 660 670 680 690 >>CCDS6947.1 SETX gene_id:23064|Hs108|chr9 (2677 aa) initn: 581 init1: 135 opt: 450 Z-score: 324.8 bits: 73.2 E(32554): 9.1e-12 Smith-Waterman score: 626; 29.5% identity (55.2% similar) in 665 aa overlap (479-1022:1931-2578) 450 460 470 480 490 500 pF1KSD SGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKT----VLQRP----LSL : :.:..: :..: : . : . : CCDS69 QLARAVLNPNPMDFCTKDLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICL 1910 1920 1930 1940 1950 1960 510 520 530 540 pF1KSD IQGPPGTGKTVTSATIVYHL----ARQGNGP-----------VLVCAPSNIAVDQLTEKI :.:::::::. : . ..:.: :.:.. :::::::: :::.: .:: CCDS69 IHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKI 1970 1980 1990 2000 2010 2020 550 560 570 pF1KSD ------------HQTG----LKVVRLCAKS-------REAIDS----------PVSFLAL . : ...::: .. . ..:: : :. CCDS69 ILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAM 2030 2040 2050 2060 2070 2080 580 590 600 610 pF1KSD HNQIRNMD-SMPELQKLQQL--------KDETGE-LSSADEKRYRALKRTAERE------ :.. . .: .. ::.. . : ..: : .:.....: . .. : . CCDS69 HKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKT 2090 2100 2110 2120 2130 2140 620 630 640 650 660 pF1KSD ---LLMNADVICCTCVGAGDPRLAK-------MQFRSILIDESTQATEPECMVPVVLGAK ..... .:::: .: : . . : ...::. :. : : ..:.. . CCDS69 QSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCN 2150 2160 2170 2180 2190 2200 670 680 690 700 710 pF1KSD QLILVGDHCQLGPVVMCKKAAKAGLSQSL---FERLVVLGIR-------PI-RLQVQYRM .:::::: :: :.:. :: . : .::. : ::. ... :: .: ::::: CCDS69 KLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRM 2210 2220 2230 2240 2250 2260 720 730 740 750 760 770 pF1KSD HPALSAFPSNIFYEGSLQ-NGVTAADRVKKGFDFQWP-QPDKPMFFYVTQGQEEIASSGT :: . :::: :. .:. : : : : .. .:: :: . : : .:.:. .. CCDS69 HPDICLFPSNYVYNRNLKTNRQTEAIRCSS----DWPFQPY--LVFDVGDGSER--RDND 2270 2280 2290 2300 2310 780 790 800 810 820 830 pF1KSD SYLNRTEAANVEKITTKLLKAGAKP---DQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQ ::.: : : .: ::.: : .::::: :..:.. ..: ... . : CCDS69 SYINVQEIKLVMEII-KLIKDKRKDVSFRNIGIITHYKAQKT-MIQK-DLDKEFDRK--G 2320 2330 2340 2350 2360 840 850 860 870 880 pF1KSD EVEIASVDAFQGREKDFIILSCVRANEHQG-IGFLNDPRRLNVALTRARYGVIIVGNPKA .:. .:::::::.:: .:..::::: :: :::: . .::::..:::.:...:.:. .. CCDS69 PAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRT 2370 2380 2390 2400 2410 2420 890 900 910 920 930 940 pF1KSD LSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSK--P---RKLVN--TINP-GARF- : .. ::.:.. ... .... .: :.. ... : : :.:.. :: : :.: CCDS69 LMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQ 2430 2440 2450 2460 2470 2480 950 960 970 980 pF1KSD --MTTAMYDAREAI--IPGSVYDRSSQGRPSSMYFQT--------HDQIGMISAGPSHVA . .. :. : . .:.: :... .. . :::. : . CCDS69 GGLPSSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQL----QDPRLLK 2490 2500 2510 2520 2530 2540 990 1000 1010 1020 1030 1040 pF1KSD AMNIPIPFNLVM-PPMPPPGYFGQANGPAAGRGTPKGKTGRGGRQKNRFGLPGPSQTNLP :.: . .. . :.: :. :.. : : CCDS69 RMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPP 2550 2560 2570 2580 2590 2600 1050 1060 1070 1080 1090 1100 pF1KSD NSQASQDVASQPFSQGALTQGYISMSQPSQMSQPGLSQPELSQDSYLGDEFKSQIDVALS CCDS69 VRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRT 2610 2620 2630 2640 2650 2660 1129 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:45:47 2016 done: Thu Nov 3 00:45:48 2016 Total Scan time: 3.620 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]