FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0222, 1163 aa 1>>>pF1KSDA0222 1163 - 1163 aa - 1163 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.0103+/-0.00125; mu= -16.4620+/- 0.073 mean_var=666.3229+/-162.301, 0's: 0 Z-trim(114.8): 191 B-trim: 833 in 1/52 Lambda= 0.049686 statistics sampled from 15168 (15358) to 15168 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.472), width: 16 Scan time: 5.150 The best scores are: opt bits E(32554) CCDS74234.1 ZNF516 gene_id:9658|Hs108|chr18 (1163) 8082 595.7 2.1e-169 CCDS32984.1 ZNF536 gene_id:9745|Hs108|chr19 (1300) 1000 88.1 1.5e-16 >>CCDS74234.1 ZNF516 gene_id:9658|Hs108|chr18 (1163 aa) initn: 8082 init1: 8082 opt: 8082 Z-score: 3154.9 bits: 595.7 E(32554): 2.1e-169 Smith-Waterman score: 8082; 100.0% identity (100.0% similar) in 1163 aa overlap (1-1163:1-1163) 10 20 30 40 50 60 pF1KSD MDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAPLGEMRASEGLDACASPTKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAPLGEMRASEGLDACASPTKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SQFERKKDLELHVHQAHKPFKCRLCSYATLREESLLSHIERDHITAQGPGSGEACVENGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SQFERKKDLELHVHQAHKPFKCRLCSYATLREESLLSHIERDHITAQGPGSGEACVENGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KTGSKNRPKSELDPIATINNVVQEEVIVAGLSLYEVCAKCGNLFTNLDSLNAHNAIHRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KTGSKNRPKSELDPIATINNVVQEEVIVAGLSLYEVCAKCGNLFTNLDSLNAHNAIHRRV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EASRTRAPAEEGAEGPSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQAWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 EASRTRAPAEEGAEGPSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQAWQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LATRGKVAEPAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKRKREQDAPAAQGPPRKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LATRGKVAEPAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKRKREQDAPAAQGPPRKR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD ASGPGDPAPAGHLDPRSAARPNRRAAATTGQGKSSECFECGKIFRTYHQMVLHSRVHRRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ASGPGDPAPAGHLDPRSAARPNRRAAATTGQGKSSECFECGKIFRTYHQMVLHSRVHRRA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RRERDSDGDRAARARCGSLSEGDSASQPSSPGSACAAADSPGSGLADEAAEDSGEEGAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RRERDSDGDRAARARCGSLSEGDSASQPSSPGSACAAADSPGSGLADEAAEDSGEEGAPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PAPGGQPRRCCFSEEVTSTELSSGDQSHKMGDNASERDTGESKAGIAASVSILENSSRET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PAPGGQPRRCCFSEEVTSTELSSGDQSHKMGDNASERDTGESKAGIAASVSILENSSRET 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD SRRQEQHRFSMDLKMPAFHPKQEVPVPGDGVEFPSSTGAEGQTGHPAEKLSDLHNKEHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SRRQEQHRFSMDLKMPAFHPKQEVPVPGDGVEFPSSTGAEGQTGHPAEKLSDLHNKEHSG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GGKRALAPDLMPLDLSARSTRDDPSNKETASSLQAALVVHPCPYCSHKTYYPEVLWMHKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GGKRALAPDLMPLDLSARSTRDDPSNKETASSLQAALVVHPCPYCSHKTYYPEVLWMHKR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD IWHRVSCNSVAPPWIQPNGYKSIRSNLVFLSRSGRTGPPPALGGKECQPLLLARFTRTQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 IWHRVSCNSVAPPWIQPNGYKSIRSNLVFLSRSGRTGPPPALGGKECQPLLLARFTRTQV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PGGMPGSKSGSSPLGVVTKAASMPKNKESHSGGPCALWAPGPDGYRQTKPCHGQEPHGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PGGMPGSKSGSSPLGVVTKAASMPKNKESHSGGPCALWAPGPDGYRQTKPCHGQEPHGAA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD TQGPLAKPRQEASSKPVPAPGGGGFSRSATPTPTVIARAGAQPSANSKPVEKFGVPPAGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TQGPLAKPRQEASSKPVPAPGGGGFSRSATPTPTVIARAGAQPSANSKPVEKFGVPPAGA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPLPPREPPSKAAQELRTLATCAAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPLPPREPPSKAAQELRTLATCAAGS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD RGDAALQAQPGVAGAPPVLHSIKQEPVAEGHEKRLDILNIFKTYIPKDFATLYQGWGVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RGDAALQAQPGVAGAPPVLHSIKQEPVAEGHEKRLDILNIFKTYIPKDFATLYQGWGVSG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD PGLEHRGTLRTQARPGEFVCIECGKSFHQPGHLRAHMRAHSVVFESDGPRGSEVHTTSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PGLEHRGTLRTQARPGEFVCIECGKSFHQPGHLRAHMRAHSVVFESDGPRGSEVHTTSAD 1090 1100 1110 1120 1130 1140 1150 1160 pF1KSD APKQGRDHSNTGTVQTVPLRKGT ::::::::::::::::::::::: CCDS74 APKQGRDHSNTGTVQTVPLRKGT 1150 1160 >>CCDS32984.1 ZNF536 gene_id:9745|Hs108|chr19 (1300 aa) initn: 1224 init1: 377 opt: 1000 Z-score: 410.7 bits: 88.1 E(32554): 1.5e-16 Smith-Waterman score: 1254; 38.3% identity (62.1% similar) in 622 aa overlap (25-606:121-727) 10 20 30 40 50 pF1KSD MDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMR : :. : . : .::: : :.: :: ::: CCDS32 EVDTSLNGRVDLQQFLNGQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMR 100 110 120 130 140 150 60 70 80 90 100 pF1KSD KHTGEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGH----EPEAGEAPLGE---MRA ::::::.:::::::::.::::::::.:.:. :.: .:. : . : : .: CCDS32 THTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRD 160 170 180 190 200 210 110 120 130 140 150 160 pF1KSD SEGLDACASPTKSASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAP .. . .: . . . .. : . . : : .. . . ... .: :: CCDS32 KQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAP 220 230 240 250 260 270 170 180 190 200 210 220 pF1KSD GEAKAAVQCSFCKSQFERKKDLELHVHQAHKPFKCRLCSYATLREESLLSHIERDHITAQ . :. .:.:::..:.....:. :.. :::.:: ::..:. .:: :.::.:. ::::. CCDS32 A---AGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAE 280 290 300 310 320 230 240 250 260 270 280 pF1KSD GP-GSGEACVENGKPELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFK . :.: :: : : .:: ::::::.:::.::::.::.::. ::.: :.::::::: CCDS32 SAQGQGP----NGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFK 330 340 350 360 370 380 290 300 310 320 330 340 pF1KSD EPWFLKNHMKAHGPKTGSKNRPKSELDP-IATINNVVQEEVIVAGLSLYEVCAKCGNLFT ::::::::::.: : . :: :: :: . . . ...:. . : : : . : . CCDS32 EPWFLKNHMKVHLNKLSVKN--KSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTP 390 400 410 420 430 440 350 360 370 380 390 pF1KSD NLDSLNAHNAIH-------RRVEA-SRTRAPAEEGAEG-PSDTKQFFLQCLNLRPSAAGD . .:. . .. .. :: .. .: :.: : :. .: :::: : .. CCDS32 DKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSS 450 460 470 480 490 500 400 410 420 430 440 450 pF1KSD SCPGTQAGRRVAELDPVNSYQAWQLATRGKVAEPA----EY-LKYGAWDEALAGDVAFDK ::. ..::.::::::::::: .:: . : . :. :. . : . : ::: CCDS32 CIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANAGVLFDK 510 520 530 540 550 560 460 470 480 490 500 pF1KSD DRREYVLVSQEKRKREQDAPAAQGPPRKRASGPGDPAPAGHLDPRSAARP------NRRA ..::::::. . : : :: : .: :. .::: ..: :. CCDS32 EKREYVLVGADGSK--QKMPADLVHSTKVGSQRDLPS---KLDPLESSRDFLSHGLNQTL 570 580 590 600 610 510 520 530 540 550 pF1KSD AATT-GQG----KSSECFECGKIFRTYHQMVLHSRVHRRARRERDSDGDRAA---RARCG . : : : .:: .::..::::::.:.:::::.: :. .. :: ... : : CCDS32 EYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEE-DGLHVGLDERRGSG 620 630 640 650 660 670 560 570 580 590 600 610 pF1KSD SLSEGDSASQPSSPGSACAAADSP-GSGLADE--AAEDSGEEGAPEPAPGGQPRRCCFSE : .:..:.:. ..:::. .. .: :.::.. : ::: . ..: . :. CCDS32 SDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGV 680 690 700 710 720 730 620 630 640 650 660 670 pF1KSD EVTSTELSSGDQSHKMGDNASERDTGESKAGIAASVSILENSSRETSRRQEQHRFSMDLK CCDS32 QQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLK 740 750 760 770 780 790 1163 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 00:46:29 2016 done: Thu Nov 3 00:46:30 2016 Total Scan time: 5.150 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]