FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0222, 1163 aa
1>>>pF1KSDA0222 1163 - 1163 aa - 1163 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.0103+/-0.00125; mu= -16.4620+/- 0.073
mean_var=666.3229+/-162.301, 0's: 0 Z-trim(114.8): 191 B-trim: 833 in 1/52
Lambda= 0.049686
statistics sampled from 15168 (15358) to 15168 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.472), width: 16
Scan time: 5.150
The best scores are: opt bits E(32554)
CCDS74234.1 ZNF516 gene_id:9658|Hs108|chr18 (1163) 8082 595.7 2.1e-169
CCDS32984.1 ZNF536 gene_id:9745|Hs108|chr19 (1300) 1000 88.1 1.5e-16
>>CCDS74234.1 ZNF516 gene_id:9658|Hs108|chr18 (1163 aa)
initn: 8082 init1: 8082 opt: 8082 Z-score: 3154.9 bits: 595.7 E(32554): 2.1e-169
Smith-Waterman score: 8082; 100.0% identity (100.0% similar) in 1163 aa overlap (1-1163:1-1163)
10 20 30 40 50 60
pF1KSD MDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAPLGEMRASEGLDACASPTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAPLGEMRASEGLDACASPTKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SQFERKKDLELHVHQAHKPFKCRLCSYATLREESLLSHIERDHITAQGPGSGEACVENGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SQFERKKDLELHVHQAHKPFKCRLCSYATLREESLLSHIERDHITAQGPGSGEACVENGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KTGSKNRPKSELDPIATINNVVQEEVIVAGLSLYEVCAKCGNLFTNLDSLNAHNAIHRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 KTGSKNRPKSELDPIATINNVVQEEVIVAGLSLYEVCAKCGNLFTNLDSLNAHNAIHRRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EASRTRAPAEEGAEGPSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQAWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EASRTRAPAEEGAEGPSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQAWQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LATRGKVAEPAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKRKREQDAPAAQGPPRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LATRGKVAEPAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKRKREQDAPAAQGPPRKR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD ASGPGDPAPAGHLDPRSAARPNRRAAATTGQGKSSECFECGKIFRTYHQMVLHSRVHRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ASGPGDPAPAGHLDPRSAARPNRRAAATTGQGKSSECFECGKIFRTYHQMVLHSRVHRRA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD RRERDSDGDRAARARCGSLSEGDSASQPSSPGSACAAADSPGSGLADEAAEDSGEEGAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RRERDSDGDRAARARCGSLSEGDSASQPSSPGSACAAADSPGSGLADEAAEDSGEEGAPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAPGGQPRRCCFSEEVTSTELSSGDQSHKMGDNASERDTGESKAGIAASVSILENSSRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PAPGGQPRRCCFSEEVTSTELSSGDQSHKMGDNASERDTGESKAGIAASVSILENSSRET
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD SRRQEQHRFSMDLKMPAFHPKQEVPVPGDGVEFPSSTGAEGQTGHPAEKLSDLHNKEHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SRRQEQHRFSMDLKMPAFHPKQEVPVPGDGVEFPSSTGAEGQTGHPAEKLSDLHNKEHSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD GGKRALAPDLMPLDLSARSTRDDPSNKETASSLQAALVVHPCPYCSHKTYYPEVLWMHKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GGKRALAPDLMPLDLSARSTRDDPSNKETASSLQAALVVHPCPYCSHKTYYPEVLWMHKR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD IWHRVSCNSVAPPWIQPNGYKSIRSNLVFLSRSGRTGPPPALGGKECQPLLLARFTRTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 IWHRVSCNSVAPPWIQPNGYKSIRSNLVFLSRSGRTGPPPALGGKECQPLLLARFTRTQV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD PGGMPGSKSGSSPLGVVTKAASMPKNKESHSGGPCALWAPGPDGYRQTKPCHGQEPHGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PGGMPGSKSGSSPLGVVTKAASMPKNKESHSGGPCALWAPGPDGYRQTKPCHGQEPHGAA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD TQGPLAKPRQEASSKPVPAPGGGGFSRSATPTPTVIARAGAQPSANSKPVEKFGVPPAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TQGPLAKPRQEASSKPVPAPGGGGFSRSATPTPTVIARAGAQPSANSKPVEKFGVPPAGA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD GFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPLPPREPPSKAAQELRTLATCAAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPLPPREPPSKAAQELRTLATCAAGS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RGDAALQAQPGVAGAPPVLHSIKQEPVAEGHEKRLDILNIFKTYIPKDFATLYQGWGVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RGDAALQAQPGVAGAPPVLHSIKQEPVAEGHEKRLDILNIFKTYIPKDFATLYQGWGVSG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD PGLEHRGTLRTQARPGEFVCIECGKSFHQPGHLRAHMRAHSVVFESDGPRGSEVHTTSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PGLEHRGTLRTQARPGEFVCIECGKSFHQPGHLRAHMRAHSVVFESDGPRGSEVHTTSAD
1090 1100 1110 1120 1130 1140
1150 1160
pF1KSD APKQGRDHSNTGTVQTVPLRKGT
:::::::::::::::::::::::
CCDS74 APKQGRDHSNTGTVQTVPLRKGT
1150 1160
>>CCDS32984.1 ZNF536 gene_id:9745|Hs108|chr19 (1300 aa)
initn: 1224 init1: 377 opt: 1000 Z-score: 410.7 bits: 88.1 E(32554): 1.5e-16
Smith-Waterman score: 1254; 38.3% identity (62.1% similar) in 622 aa overlap (25-606:121-727)
10 20 30 40 50
pF1KSD MDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMR
: :. : . : .::: : :.: :: :::
CCDS32 EVDTSLNGRVDLQQFLNGQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMR
100 110 120 130 140 150
60 70 80 90 100
pF1KSD KHTGEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGH----EPEAGEAPLGE---MRA
::::::.:::::::::.::::::::.:.:. :.: .:. : . : : .:
CCDS32 THTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRD
160 170 180 190 200 210
110 120 130 140 150 160
pF1KSD SEGLDACASPTKSASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAP
.. . .: . . . .. : . . : : .. . . ... .: ::
CCDS32 KQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAP
220 230 240 250 260 270
170 180 190 200 210 220
pF1KSD GEAKAAVQCSFCKSQFERKKDLELHVHQAHKPFKCRLCSYATLREESLLSHIERDHITAQ
. :. .:.:::..:.....:. :.. :::.:: ::..:. .:: :.::.:. ::::.
CCDS32 A---AGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAE
280 290 300 310 320
230 240 250 260 270 280
pF1KSD GP-GSGEACVENGKPELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFK
. :.: :: : : .:: ::::::.:::.::::.::.::. ::.: :.:::::::
CCDS32 SAQGQGP----NGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFK
330 340 350 360 370 380
290 300 310 320 330 340
pF1KSD EPWFLKNHMKAHGPKTGSKNRPKSELDP-IATINNVVQEEVIVAGLSLYEVCAKCGNLFT
::::::::::.: : . :: :: :: . . . ...:. . : : : . : .
CCDS32 EPWFLKNHMKVHLNKLSVKN--KSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTP
390 400 410 420 430 440
350 360 370 380 390
pF1KSD NLDSLNAHNAIH-------RRVEA-SRTRAPAEEGAEG-PSDTKQFFLQCLNLRPSAAGD
. .:. . .. .. :: .. .: :.: : :. .: :::: : ..
CCDS32 DKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSS
450 460 470 480 490 500
400 410 420 430 440 450
pF1KSD SCPGTQAGRRVAELDPVNSYQAWQLATRGKVAEPA----EY-LKYGAWDEALAGDVAFDK
::. ..::.::::::::::: .:: . : . :. :. . : . : :::
CCDS32 CIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANAGVLFDK
510 520 530 540 550 560
460 470 480 490 500
pF1KSD DRREYVLVSQEKRKREQDAPAAQGPPRKRASGPGDPAPAGHLDPRSAARP------NRRA
..::::::. . : : :: : .: :. .::: ..: :.
CCDS32 EKREYVLVGADGSK--QKMPADLVHSTKVGSQRDLPS---KLDPLESSRDFLSHGLNQTL
570 580 590 600 610
510 520 530 540 550
pF1KSD AATT-GQG----KSSECFECGKIFRTYHQMVLHSRVHRRARRERDSDGDRAA---RARCG
. : : : .:: .::..::::::.:.:::::.: :. .. :: ... : :
CCDS32 EYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEE-DGLHVGLDERRGSG
620 630 640 650 660 670
560 570 580 590 600 610
pF1KSD SLSEGDSASQPSSPGSACAAADSP-GSGLADE--AAEDSGEEGAPEPAPGGQPRRCCFSE
: .:..:.:. ..:::. .. .: :.::.. : ::: . ..: . :.
CCDS32 SDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGV
680 690 700 710 720 730
620 630 640 650 660 670
pF1KSD EVTSTELSSGDQSHKMGDNASERDTGESKAGIAASVSILENSSRETSRRQEQHRFSMDLK
CCDS32 QQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLK
740 750 760 770 780 790
1163 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:46:29 2016 done: Thu Nov 3 00:46:30 2016
Total Scan time: 5.150 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]